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PREMIUM QUALITY FEED-ENHANCER
GENEX SOWSPECIES
PIGS
Supporting the reproductive cycle
GENEX
ESSENTIALS OILS
PLANT EXTRACTS
ORGANIC ACIDS PhyLLOSILICATES
Background
Today’s farming production systems are more intensive and
much more is expected from farm animals. The modern
sow is a totally different animal to that of 25-30 years
ago. Genetic improvements have led to highly prolific
sows with the ability to produce greater numbers of
piglets each cycle. Every aspect of a sow’s management
must be correct in order to obtain the maximum number
of piglets. These piglets need to be healthy, viable and
have good birth weights in order to achieve maximum
profitability. Farmers must manage the bacterial challenge
from the environment to safeguard their profits.
Common threats to a farm’s profitability are E. coli and
other pathogens. Genex Sow protects against these
harmful bacteria which are often consumed via the feed.
Genex Sow uses a unique blend of organic acids, essential oils and plants extracts, which means that the effect of Genex Sow is not via a simple pH reduction effect.
Organic acids are used to control potentially pathogenic bacteria. Genex Sow is formulated using a unique blend of organic acids combined with a stable carrier. It’s the types of acids used in Genex Sow that make the difference.
By combining all of these components, Genex Sow provides excellent protection against feed borne pathogens.
This unique blend of active ingredients used in Genex Sow is born of intensive R&D. It is not just the ingredients themselves that gives the product its unique properties. It is the ratio of those ingredients and balance between them which combine to achieve the optimal synergistic effect. By examining the potential of each material and considering how it may enhance the efficacy of the other components, the researchers at Optivite designed the ultimate formulation that makes Genex Sow so effective.
• Multiplesynergisticassociations:bacteriostatic and bactericide effect in feed.
• Protectsintestinalmucosaandvillifromharmful bacterial consumed via the feed.
• Helpstheanimalachievetheoptimalintestinal microbial balance by reducing exposure to contaminated feed.
• Supportsanimalhealthanddigestive function.
• Phyllosilicatecarrierknowntoadsorbmycotoxins and endotoxins.
• Phyllosilicatecarrierenablesslowrelease of active components
The benefits of reducing pathogenic infection:GESTATION
• Increasedlittersize
• Increasedbirthweight
• Improvedconceptionrates/lessreturns
• Decreasedbirthweightvariability
• Lessrunts
LACTATION
• Betterearlyperformance
• Increasedweaningweights
• Decreasedvariationinweaningweights
GENEX SOW do?What does
Organic acids – Their effect on lactobacilli bacteria
A similar process also takes place in lactic acid producing bacteria – lactobacilli. However, our acids target the harmful bacteria not the beneficial bacteria that contribute to a healthy gut.
GENEX SOW:
HOW DOES GENEX SOW WORK?
The ScienceThe pathogenic challengeBacteria such as E. coli are a major threat to sows and their piglets. There are many possible sources of infection of which feed can be a main route.
Intestinal wall microvilli, microscopic cellular membrane protrusions that are responsible for a wide variety of functions including absorption of nutrients, can be seriously damaged by E. coli and other pathogens. This can lead to the malabsorption of nutrients reducing the efficiency of digestion and inhibiting animal performance.
Organic acidsThe effect of Genex Sow is not a simple pH reduction by the acids. Genex Sow is formulated using a unique blend of organic acids combined with a stable carrier that make a difference.
Why use organic acids?Organic acids are used to control potentially pathogenic bacteria because of their ability to penetrate the bacterial cell wall of Gram-negative bacteria. Once the cell has been compromised the organic acids catastrophically disrupt cell metabolism, thus killing the bacteria.
Genex Sow vs. E. coli in finished feed
Organic acids – their effect on Gram-negative enterobacteria e.g. E. coli:
Organic acids (AH) consist of two components, negatively charged anions (A-) and positively charged hydrogen ions or cations (H+).
=Hydrogen/Cations (Positivelycharged)
= Anions (Negatively charged)
KEY:
STEP 1 – The acid penetrates the cell wall
AH move into the cell & split up acidifying the internal cell environment.In order to maintain the neutrality of the internal environment, the cell moves to step 2.
STEP 1 – The acid penetrates the cell wall
Lactobacilliareacidtolerant,soareableto cope with a greater pH shift.
STEP 2 – Removal of cations
The cell uses energy to power the proton pumps which move H+ out of the cell.
STEP 2 – Removal of cations
LessenergyusedinmovingH+outofthecell.
STEP 3–Celldies
As the cell is using all of its available energy moving H+ out of the cell normal cell function is impaired.Inhibition of DNA replacement occurs leading to cell death.
STEP 3–Cellsurvives
The energy expended is low meaning more energy is available for normal cell function and viability.
2000
1500
1000
500
0
04
8HOURS
CONTROL
COU
NT
PER
GRA
M O
F SA
MPL
E
2448GENEX
E. coli adheres to the intestinal mucosa causing the destruction of intestinal microvilli
(After Dr David Dean, Institute of Cell & Molecular Biosciences, University of Newcastle, UK)
Healthy microvilli
Challenged microvilli
Untreated cells (control)(Afetr Burt & Reinders, Letters in Applied Microbiology (2003) 36: 162–167)
Cells damaged after treatment with essential oil
The essential oils in Genex• Stimulate feed intake
• Damage microorganism cell wall structure - Cell contents lost - Disrupts cell homeostasis/genetic material replication - Allows more organic acid into cell
• Prevent flagella formation - Limits movement - Limits growth & multiplication
The plant extracts in Genex• Natural surfactants
- Coats bacteria - Damages bacterial cell wall - Cell contents lost - Allows more organic acid into cell - Enhances essential oil effect
By combining all of these components, Genex Sow provides excellent protection against pathogens, including E. coli.
10
No. OFTRIALS
11.09
CONTROLNo. PIGS
BORN ALIVE
11.53
GENEX SOWNo. PIGS
BORN ALIVE
+ 0.44
IMPROVEMENT(No)
BIRTH WEIGHT(kg)
COEFFICIENT OFVARIATION (%)
1.35
15.91
BEFORE
1.53
12.90
GENEX SOW
+ 0.18
3.01
IMPROVEMENT
< 0.001
0.252
P VALUE
WEANING WEIGHT(kg)
COEFFICIENT OFVARIATION (%)
5.52
16.09
BEFORE
6.33
11.81
GENEX SOW
+ 0.81
4.28
IMPROVEMENT
< 0.001
0.049
P VALUE
o
10
20
30
40
50
6o
70
80
POST
WEA
NIN
G G
AIN
(g/d
)M
ORT
ALIT
Y (%
)
0.1
0
0.2
0.3
0.4
0.5
0.6 30
25
20
15
10
5
0
DAY
25 W
EIG
HT
(kg)
WEA
NIN
G W
EIG
HT
(kg)
4.51
100 200 300 400 500 600
1.2 1.4 1.6 1.8 2
5
5.5
6
6.5
7
BIRTH WEIGHT (kg)0.8 0.8 - 1 1-1.25 1.25-1.5 1.5-1.8 >1.8
BIRTH WEIGHT (kg)
3.5 4.5 5.5 6.5 7.5 8.5 9.5 10.5WEANING WEIGHT (kg) DAILY LIVE WEIGHT GAIN POST WEANING (g/d)
20
0
40
60
80
100
120
140
160
DAYS
: BIR
TH TO
SLA
UG
HTE
R
Using
Benefits of GENEX SOW
GENEX SOW
• Increasedpigletsperlitter
• Increasedbirthweight
• Fasterpigletgrowth
• Heavierweaningweights
• Improvedlitteruniformity
• Moreproductivesows
Reduces microbial challenge from feed which can give
Effect on weaning weight
Inclusion rates
Effect on birth weight
Effects on numbers born alive
By using Genex Sow in feed as part of an overall bacterial control strategy, the following has been observed.
To control bacterial levels (in particular E. coli) in feed as part of an overall reduction strategy offers a number of benefits.
Leads to increased birth weight, reducing piglet mortality
(Broekman,85)
(Bilkei, 99)
(Cole & Varley, 2000)
(Cole & Varley, 2000)
Improved weaning weights improves post weaning gain
Improving weaning weights
Faster to slaughter
4kg/t
DRY / GESTATING SOWS
4kg/t
LACTATING SOWS WHEN ENCOUNTERING A SEVERE CHALLENGE
PLEASE CONSULT YOUR OPTIVITE NUTRITIONIST
GENEX SOW:
The SupportOptivite distributor countries
ContactOptivite Manton Wood Enterprise Park Worksop, S80 2RS, UK www.optivite.com
Email: [email protected] [email protected]
t: +44 (0)1909 537380 f: +44 (0)1909 478919
Optivite provides cutting-edge, science based products plus the support you need. Optivite’s nutritionists and animal husbandry specialists are available with expert advice, service and product knowledge, with regional sales and technical support people on-hand to assist with day-to-day challenges. What’s more, our global distributor network is here to guide you to the right product choices wherever you are in the world.
