2007

Urea derivativesQ 0640 Synthesis and Bioassay Evaluation of 1-[4-(Methyleneaminooxymethyl)phenyl]-

-3-(2,6-difluorobenzoyl)ureas. — The reaction of isocyanate (I) with a variety of anilines (II) affords the title ureas (III) (14 examples), soluble in most organic solvents. Some derivatives show excellent insecticidal activity against Mythimna separata and a moderate one against Nephotettix cincticeps. Compound (IIIf) exhibits acaricidal ef-fects against Tetranychus urticae. — (CHEN, L.; OU, X.-M.; MAO, C.-H.; SHANG, J.; HUANG, R.-Q.; BI, F.-C.; WANG*, Q.-M.; Bioorg. Med. Chem. 15 (2007) 11, 3678-3683; State Key Lab. Elem.-Org. Chem., Nankai Univ., Tianjin 300071, Peop. Rep. China; Eng.) — Klein

37- 089