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The 7 steps of Homology modeling
1: Template recognition and initial alignment
1: Template recognition and initial alignment
2: Alignment correction
1: Template recognition and initial alignment
2: Alignment correction
1: Template recognition and initial alignment
2: Alignment correction
3: Backbone generation
1: Template recognition and initial alignment
2: Alignment correction
3: Backbone generation
4: Loop modeling
4: Loop modeling
Known structure GVCMYIEA---LDKYACNC
Your sequence GECFMVKDLSNPSRYLCKC
1: Template recognition and initial alignment
2: Alignment correction
3: Backbone generation
4: Loop modeling
5: Sidechain modeling
1: Template recognition and initial alignment
2: Alignment correction
3: Backbone generation
4: Loop modeling
5: Sidechain modeling
6: Model optimization
1: Template recognition and initial alignment
2: Alignment correction
3: Backbone generation
4: Loop modeling
5: Sidechain modeling
6: Model optimization
7: Model validation
1: Template recognition and initial alignment
2: Alignment correction
3: Backbone generation
4: Loop modeling
5: Sidechain modeling
6: Model optimization
7: Model validation
8: Iteration
8: Iteration
8: Iteration
8: Iteration
Model!
1: Template recognition and initial alignment
2: Alignment correction
3: Backbone generation
4: Loop modeling
5: Sidechain modeling
6: Model optimization
7: Model validation
8: Iteration
8: Iteration
8: Iteration
8: Iteration
7 steps of homology modeling
1: Template recognition and initial alignment2: Alignment correction3: Backbone generation4: Loop modeling5: Side-chain modeling6: Model optimization7: Model validation8: Iteration
Alignment
Modeling
Correction
