Upload
sorina-madalina
View
217
Download
0
Embed Size (px)
Citation preview
8/18/2019 The Accidental Discovery of Insulin
1/15
8/18/2019 The Accidental Discovery of Insulin
2/15
#$ Definition of %nsulin&$ !oles of %nsulin
'$ (he accidental discovery of %nsulin)$ Diseases*$ Synthetic insulin+$ (he obel -ri.e/$ Bibliogra"hy
Contens
8/18/2019 The Accidental Discovery of Insulin
3/15
1. Definition of %nsulin
• Insulin is a hormone produced in thepancreas which regulates the amountof glucose in the blood.
8/18/2019 The Accidental Discovery of Insulin
4/15
2.Roles of Insulin
Insulin regulateshow the body usesand stores glucose
and fat
Insulin helps cellsto take in glucose
to be used forenergy.
If the body hassu cient energy,insulin signals the
liver to take upglucose and store
it as glycogen
8/18/2019 The Accidental Discovery of Insulin
5/15
3.The accidental discovery of Insulin
• In 1921 two researchers, Fredanting and !harles est were
looking for a cure for diabetes"• #hey start to perform their
e$periments using animals
8/18/2019 The Accidental Discovery of Insulin
6/15
%.#he accidental discovery of Insulin
• #o test theirtheory antingand est used
1& dogs.
8/18/2019 The Accidental Discovery of Insulin
7/15
%.#he accidental discovery of Insulin
• #hey made thedogs diabetic andthen investigatedtreatments for thediabetes.
• #he result of their
research hassaved the lives ofmillions of people.
8/18/2019 The Accidental Discovery of Insulin
8/15
The islets ofLangerhans are theregions ofthe "ancreas thatcontain its endocrine
8/18/2019 The Accidental Discovery of Insulin
9/15
)$Diseases• (y"e # diabetes : t he body1s o2n
immune cells attac3 the insulin
"roducing beta cells of the "ancreas$• (his leads to an absolute insulindeficiency
8/18/2019 The Accidental Discovery of Insulin
10/15
)$Diseases
(y"e &:•
body fails to• "roduce the re4uiredamount of insulin
8/18/2019 The Accidental Discovery of Insulin
11/15
)$Diseases
%nsulinoma:the "ancreas is"roducing too
much insulin
8/18/2019 The Accidental Discovery of Insulin
12/15
'.(ynthetic Insulin• (ynthetic insulin is made in
laboratories and is used by thosewitch body can)t produce insulin"
8/18/2019 The Accidental Discovery of Insulin
13/15
+$(he obel -ri.e
• #he news of thesuccessful treatmentof diabetes withinsulin rapidly spread"
• In 192% the *obel!ommittee decided to
award anting andest the *obel +ri e
in +hysiology or
-edicine.
8/18/2019 The Accidental Discovery of Insulin
14/15
/$ Bibliogra"hy
• http //www.nobelpri e.org/educational/medicine/insulin/discovery0insulin.html
• http //themedicalbiochemistrypage.org/insulin.php
http://www.nobelprize.org/educational/medicine/insulin/discovery-insulin.htmlhttp://www.nobelprize.org/educational/medicine/insulin/discovery-insulin.htmlhttp://www.nobelprize.org/educational/medicine/insulin/discovery-insulin.htmlhttp://themedicalbiochemistrypage.org/insulin.phphttp://themedicalbiochemistrypage.org/insulin.phphttp://themedicalbiochemistrypage.org/insulin.phphttp://themedicalbiochemistrypage.org/insulin.phphttp://www.nobelprize.org/educational/medicine/insulin/discovery-insulin.htmlhttp://www.nobelprize.org/educational/medicine/insulin/discovery-insulin.htmlhttp://www.nobelprize.org/educational/medicine/insulin/discovery-insulin.html
8/18/2019 The Accidental Discovery of Insulin
15/15
Thank you for yourattention