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CLINICAL APPLICATIONS LESSON PLAN THE PURITAN BENNETT™ 980 VENTILATOR

THE PURITAN BENNETT™ 980 VENTILATOR · Puritan BennettTM 980 Series Ventilator Operator’s Manual Leak Sync Addendum Page B-2 2. Oto J et al. A Comparison of Leak Compensation

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Page 1: THE PURITAN BENNETT™ 980 VENTILATOR · Puritan BennettTM 980 Series Ventilator Operator’s Manual Leak Sync Addendum Page B-2 2. Oto J et al. A Comparison of Leak Compensation

CLINICAL APPLICATIONS LESSON PLAN

THE PURITAN BENNETT™ 980 VENTILATOR

Page 2: THE PURITAN BENNETT™ 980 VENTILATOR · Puritan BennettTM 980 Series Ventilator Operator’s Manual Leak Sync Addendum Page B-2 2. Oto J et al. A Comparison of Leak Compensation

OVERVIEW

This guide is provided as a convenience companion document to the Operator’s Manual. It is not intended to replace the Operator’s Manual, which should always be available while using the ventilator. It is important to familiarize yourself with all information in the Operator’s Manual relevant to your institution’s use of the ventilator, including on-screen help, instructions, warnings and cautions.

Page 3: THE PURITAN BENNETT™ 980 VENTILATOR · Puritan BennettTM 980 Series Ventilator Operator’s Manual Leak Sync Addendum Page B-2 2. Oto J et al. A Comparison of Leak Compensation

Puritan Bennett™ Leak Sync Software

Noninvasive Ventilation

Volume Control Plus

Pressure Control

Puritan Bennett™ BiLevel Software

Puritan Bennett™ PAV™ *+ Software

Tube Compensation Software

Volume Support

Puritan Bennett™ NeoMode 2.0 Software

Puritan Bennett™ Proximal Flow Sensor

CONTENTS

3 3 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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PURITAN BENNETT™ LEAK SYNC SOFTWARE

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Patient interface

ETT (cuffed, deflated cuff or cuffless)

Trach tube (cuffed, deflated cuff or cuffless)

Mask or other external interface

Breathing circuit system

PROBLEM: WHERE DO LEAKS COME FROM?

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Auto-triggering

Late cycling-off of pressure support and volume support breaths

Overestimation of delivered tidal volume/flow

The possible need for frequent manual adjustments

PROBLEM: COMMON LEAK CHALLENGES

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Year Author Key Results

2010 Mahmoud1 An air leak of 40% indicated the displayed VT was underestimated by 1.2 mL/kg, thus by about 24% of target VT (generally 5 mL/kg).

2001 Main2 Leaks larger than 20% resulted in inconsistent tidal volume delivery and gross overestimation of compliance (C) and resistance (R) regardless of ventilator mode.

1. Mahmoud RA, Proquitté H, Fawzy N, Bührer C, Schmalisch G. Tracheal tube airleak in clinical practice and impact on tidal volume measurement in ventilated neonates. Pediatr Crit Care Med. 2011;12(2):197-202.

2. Main E, Castle R, Stocks J, James I, Hatch D. The influence of endotracheal tube leak on the assessment of respiratory function in ventilated children. Intensive Care Med. 2001;27(11):1788-1797.

Studies show that air leaks occur in up to 70% of children and can lead to significant clinical consequences, including1,2:

Inconsistent ventilatory delivery1

Unreliable lung function testing2

Inappropriate clinical assessment due to error in monitored volume1

Increased work of breathing due to trigger asynchronies2

PROBLEM: LEAKS

7 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

Page 8: THE PURITAN BENNETT™ 980 VENTILATOR · Puritan BennettTM 980 Series Ventilator Operator’s Manual Leak Sync Addendum Page B-2 2. Oto J et al. A Comparison of Leak Compensation

Leak Sync software may reduce leak-related ventilation and monitoring problems* during both inspiration and exhalation.1

1. Oto J et al. A Comparison of Leak Compensation in Acute Care Ventilators During Noninvasive and Invasive Ventilation: A Lung Model Study Respir Care 2013;58(12):2027–2037 (Puritan Bennett™ 840 Leak comp software was in the study).

*Compared to when Leak Sync is off

SOLUTION: PURITAN BENNETT™ LEAK SYNC SOFTWARE

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Reduces auto-triggering and delayed cycling1

Leak compensates the data values for VTI (displayed as VTL) and VTE

Servo-controls breath delivery based on leak-compensated values

Works in VC+ and VS

SOLUTION: PURITAN BENNETT™ LEAK SYNC SOFTWARE

9 9 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

1. Oto J et al. A Comparison of Leak Compensation in Acute Care Ventilators During Noninvasive and Invasive Ventilation: A Lung Model Study Respir Care 2013;58(12):2027–2037 (Puritan Bennett™ 840 Leak comp software was in the study).

Page 10: THE PURITAN BENNETT™ 980 VENTILATOR · Puritan BennettTM 980 Series Ventilator Operator’s Manual Leak Sync Addendum Page B-2 2. Oto J et al. A Comparison of Leak Compensation

Name: “Leak Compensation” changed to “Leak Sync”

VC+ and VS added

Defaults to ON with NIV and neonatal

PURITAN BENNETT™ LEAK SYNC SOFTWARE UPDATES

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May reduce manual adjustments

of sensitivity settings1

Improves triggering and cycling2

Leak compensates the data values for inspiratory and expiratory volumes to

make them more relevant to the clinical

situation1

Allows for VC+ and VS

Enables avoidance of nuisance alarms

May provide reassurance of appropriate

level of ventilatory support by servo-

controlling volume-targeted breath types

from a leak-compensated VTI (displayed at VTL) data value1

POTENTIAL BENEFITS OF PURITAN BENNETT™ LEAK SYNC SOFTWARE

11 11 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

1. Puritan BennettTM 980 Series Ventilator Operator’s Manual Leak Sync Addendum Page B-2

2. Oto J et al. A Comparison of Leak Compensation in Acute Care Ventilators During Noninvasive and Invasive Ventilation: A Lung Model Study Respir Care 2013;58(12):2027–2037 (Puritan Bennett™ 840 Leak comp software was in the study).

Page 12: THE PURITAN BENNETT™ 980 VENTILATOR · Puritan BennettTM 980 Series Ventilator Operator’s Manual Leak Sync Addendum Page B-2 2. Oto J et al. A Comparison of Leak Compensation

Menu tab/setup/more settings

Enabled or disabled

Enabled by default with neonatal patient type and also when NIV is selected

Set DSENS in L/min

PURITAN BENNETT™ LEAK SYNC SOFTWARE SETUP

12 12 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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LS on vent setup button

DSENS = L/min (not %)

VTL and VTE = estimated patient values

Graphic displays estimated lung flows

Data displayed:

VLEAK

%LEAK

LEAK (leak rate@PEEP)

DISPLAY CHANGES WITH LEAK SYNC SOFTWARE ENABLED

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The Puritan Bennett™ 840 ventilator with Leak Compensation software outperformed all other ventilators included in the studies.1

Invasive ventilation The Puritan Bennett™ 840 ventilator outperformed all other

ventilators in this study by requiring fewer breaths to achieve

synchronization during increasing and decreasing leaks.1

Noninvasive ventilation

The study demonstrated wide variations between the ability

of ventilators to compensate for an air leak during noninvasive

ventilation.1

The Puritan Bennett™ 840 and Philips RespironicsTM* V60

ventilators were the only ventilators in this study that adapted

well to increasing or decreasing leaks.1

1. Oto J, Marchese A, Kacmarek M. A comparison of leak compensation in acute care ventilators during invasive ventilation: a lung model study. Respir Care. 2013;58:2027-2037.

PERFORMANCE

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Defaults on: NIV or Neonatal

Defaults off: INV/Pediatric or Adult

Adjusts within ~ 3 breaths

VTL and VTE compensated display

Flow/volume graphics leak compensated

Bias flow automatically adjusted

HOW PURITAN BENNETT™ LEAK SYNC SOFTWARE WORKS

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Capabilities

Neonate, pediatric and adult invasive and non-invasively

Dynamic compensation of leaks during invasive and noninvasive ventilation

Limitations

Leak Sync software not active with:

Tube compensation (TC)

Proportional Assist™* Ventilation (PAV™ *+ software)

CAPABILITIES AND LIMITATIONS

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NONINVASIVE VENTILATION

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Mechanical ventilation may lead to significant asynchrony.1

Leaks may impact patient tolerance to NIV.2

Leaks may result in monitoring errors, breath management issues, and trigger and cycle asynchrony.2

1. Mahmoud RA, Proquitté H, Fawzy N, Bührer C, Schmalisch G. Tracheal tube airleak in clinical practice and impact on tidal volume measurement in ventilated neonates. Pediatr Crit Care Med. 2011;12(2):197-202.

2. Vignaux L, Vargas F, Roeseler J, et al. Patient-ventilator asynchrony during non-invasive ventilation for acute respiratory failure: a multicenter study. Intensive Care Med. 2009;35(5):840-846.

PROBLEM: INVASIVE AND NONINVASIVE VENTILATION PRESENT CHALLENGES

18 18 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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NIV ventilation selection

Use with mask or other leak-prone patient interface

Works with various modes/breath types

Leak Sync software enabled

SOLUTION: NON-INVASIVE VENTILATION (NIV) WITH PURITAN BENNETT™ LEAK SYNC SOFTWARE

19 19 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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Help patients tolerate NIV so they can continue using NIV

Help avoid complications associated with intubation/artificial airways1

1. Epstein S. Should a Patient Be Extubated and Placed on Noninvasive Ventilation After Failing a Spontaneous Breathing Trial? Respir Care 2010;55(2):198–206

POTENTIAL BENEFITS OF NIV WITH PURITAN BENNETT™ LEAK SYNC SOFTWARE

20 20 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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Setup button

Menu tab/vent

NIV

Shows applicable settings

CPAP mode is available

Flow trigger

↑TI SPONT limit

DSENS defaults to OFF

NIV SETUP

21 21 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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NIV-compatible selection of mode and breath types (NEO CPAP added) is available

Volume alarms are disabled to reduce nuisance alarms

Leak Sync software automatically enabled

HOW NIV SOFTWARE WORKS

22 22 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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Capabilities

Stable respiratory drive

Neonatal

Pediatric

Adult

Limitations

Not available with:

Tube compensation (TC)

BiLevel

VC+ and VS

Proportional Assist™* Ventilation Plus (PAV™ *+ software) breath types

Only flow triggering is available.

NIV CAPABILITIES AND LIMITATIONS

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VOLUME CONTROL PLUS

Page 25: THE PURITAN BENNETT™ 980 VENTILATOR · Puritan BennettTM 980 Series Ventilator Operator’s Manual Leak Sync Addendum Page B-2 2. Oto J et al. A Comparison of Leak Compensation

PROBLEM: FIXED FLOW PATTERNS MAY RESULT IN DISCOMFORT AND ASYNCHRONY

25 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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VC+ breaths deliver a variable flow.

The ventilator manages inspiratory pressure to achieve the desired tidal volume target.

SOLUTION: VOLUME CONTROL PLUS (VC+)

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Unlike standard VC, VC+:

Provides variable flow delivery and volume

Uses the lowest pressure necessary for volume delivery

Escalates pressure if volume delivery decreases

Active valve accommodates breathing variations.

POTENTIAL BENEFITS OF VC+

27 27 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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Select:

Gender and height or predicted body weight (PBW)

Invasive vent type

AC or SIMV mode

VC+ mandatory breath type

Adjust all available settings.

Set all appropriate alarms.

VC+ SETUP

28 28 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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Variable flow with active exhalation valve

Titration of pressure

1 – 3 cmH2O/breath

Alarm strategy

↑PPEAK limit (determines max target pressure)

↓PPEAK limit

Volume not delivered

↑ VTI limit

HOW VC+ SOFTWARE WORKS AND ALARM STRATEGY

29 29 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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Check that TI is long enough.

Check that Rise Time is fast enough.

Check that the set tidal volume is not too high in comparison with the ↑PPEAK limit.

Check for auto-PEEP causing ↑PPEAK limit and resolve.

TROUBLESHOOTING INADEQUATE VT DELIVERY

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Capabilities

Neonate, pediatric and adult

Leak Sync software compatible

Limitations

Invasive only

High effort may result in regulating of pressure down to undesirable levels.

Leaks without Leak Sync software enabled may result in regulating of pressure down to undesirable levels.

CAPABILITIES AND LIMITATIONS

31 31 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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PRESSURE CONTROL

Page 33: THE PURITAN BENNETT™ 980 VENTILATOR · Puritan BennettTM 980 Series Ventilator Operator’s Manual Leak Sync Addendum Page B-2 2. Oto J et al. A Comparison of Leak Compensation

Fixed flow patterns in VC may result in discomfort and asynchrony.

VC+ may not always provide a consistent delivered pressure.

TWO PROBLEMS

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PC breaths deliver variable flow and volume.

The inspiratory pressure target remains constant.

SOLUTION: PRESSURE CONTROL (PC)

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Mean airway pressure more consistent while allowing more natural breathing.

POTENTIAL BENEFITS OF PC

35 35 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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Enter the patient’s gender and height or predicted body weight (PBW).

Select INV or NIV.

Touch AC or SIMV mode.

Touch the PC mandatory breath type.

Adjust all available settings.

Set all appropriate alarms.

PC SETUP

36 36 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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The user determines whether to set Inspiratory Time, I:E Ratio or Expiratory Time as the primary setting.

Changes in the preset rate will not alter the primary variable set in the timing padlocked area.

HOW TO USE THE TIMING PADLOCKS

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Mandatory, assisted/controlled pressure-based breath

INV or NIV

The user sets inspiratory time, inspiratory pressure/PEEP and pressure rise.

The ventilator manages flow to meet the patient’s needs and control pressure delivery.

HOW PC SOFTWARE WORKS

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Capabilities

May be used with neonate, pediatric and adult patients.

May be combined with Leak Sync.

Limitations

Tidal volume is variable.

CAPABILITIES AND LIMITATIONS

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PURITAN BENNETT™ BILEVEL SOFTWARE

Page 41: THE PURITAN BENNETT™ 980 VENTILATOR · Puritan BennettTM 980 Series Ventilator Operator’s Manual Leak Sync Addendum Page B-2 2. Oto J et al. A Comparison of Leak Compensation

The limitations of volume control may lead to additional sedation.1

Inverse ratios and monitoring are limitations in traditional PCV.

1. Pohlman M. Excessive tidal volume from breath stacking during lung-protective ventilation for acute lung injury. Crit Care Med. 2008;36:3019–3023.

TWO PROBLEMS

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Mandatory-assisted and spontaneous-assisted pressure-based breath types

Active valve

Strategies for boosting mean airway pressure

Normal I:E or extended inverse available (>4:1)

SOLUTION: PURITAN BENNETT™ BILEVEL SOFTWARE

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Flow and volume variable

Active valve

Conventional or APRV style of breath timing

Potential for improved oxygenation1

Potential for reduction in sedation1

1. Putensen C. et al. Long-Term Effects of Spontaneous Breathing During Ventilatory Support in Patients with Acute Lung Injury. Am J Respir Crit Care Med Vol 164. pp 43–49, 2001

POTENTIAL CLINICAL BENEFITS OF PURITAN BENNETT™ BILEVEL SOFTWARE

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Enter gender and height or predicted body weight (PBW).

Touch Invasive.

Touch BiLevel mode.

Adjust available settings. Note:

PH: Above ambient, not above PEEP; must be set at least 5 above PL

Spontaneous Type: TC or PS

Set all appropriate alarms.

PURITAN BENNETT™ BILEVEL SOFTWARE SETUP

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User determines the primary setting. Options:

TH (Time High)

TH ratio to TL (Time High to Time Low ratio)

TL (Time Low)

Changes in set frequency will not alter the primary variable set in the timing padlocked area.

PURITAN BENNETT™ BILEVEL SOFTWARE SETUP: TIMING PADLOCK TO LOCK ‘RELEASE TIME’

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PH: Pressure during the TH period

PL: Pressure during the TL period

When TH:TL > 4:1, with the TL period locked, changes in set f will change the TH, but the TL will remain constant regardless of patient effort period to accommodate the new f setting while maintaining the set TL period.

PURITAN BENNETT™ BILEVEL SOFTWARE SETUP

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Two pressure levels, breath availability and active valve

Conventional or APRV breath timing

Alarm strategy

PPEAK (peak pressure) may be 1 to 2 cmH2O higher than set pressure

HOW PURITAN BENNETT™ BILEVEL SOFTWARE WORKS

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Pressure support

Works on PL and PH

PL + PS = target pressure

May be left at “0” cmH20

Tube Compensation

PURITAN BENNETT™ BILEVEL SOFTWARE: SPONTANEOUS SUPPORT OPTIONS

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Capabilities

Neonate, pediatric, adult

APRV inverse ratio settings

Support Spont breaths with PS, TC

Limitations

Only invasive

Limited respiratory mechanics

CAPABILITIES AND LIMITATIONS

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PH – High Pressure

TH – High Pressure Time

Habashi NM. Other approaches to open-lung ventilation: airway pressure release ventilation. Crit Care Med. 2005;33(3 Suppl):S228-40.

DESCRIBE CHANGES THAT MAY IMPACT OXYGENATION

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PURITAN BENNETT™ PAV™*+ SOFTWARE

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Levine et al. Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans. NEJM. 2008;358:1327-1335.

PROBLEM: WHEN THE VENTILATOR CONTROLS BREATHS INSTEAD OF THE PATIENT, ATROPHY OF DIAPHRAGM FIBERS HAPPENS RAPIDLY DUE TO DISUSE

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24% of mechanically ventilated patients exhibit patient-ventilator asynchrony in >10% of their respiratory efforts.

Thille A. Patient-ventilator asynchrony during assisted mechanical ventilation. Intensive Care Med. 2006;32:1512.

PROBLEM: PATIENT-VENTILATOR ASYNCHRONY IS PREVALENT

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Asynchrony

Sedation

Prolonged ventilation time1

Possible muscle atrophy2 and VAP3

Weaning is delayed

1. Kollef M et al. The use of continuous intravenous sedation is associated with prolongation of mechanical ventilation. Chest. 1998;114:541–548.

2. Levine S et al. Rapid Disuse Atrophy of Diaphragm Fibers in Mechanically Ventilated Humans. NEJM. 2008;358:1327- 1335.

3. Rello J et al. Epidemiology and outcomes of ventilator-associated pneumonia in a large US database. Chest. 2002;122:2115-2121.

PROBLEM: ASYNCHRONY MAY LEAD TO THE USE OF SEDATION

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24% of ICU patients exhibit asynchrony in greater than 10% of their breaths.1

Asynchrony is associated with 18 extra days on the ventilator: duration of mechanical ventilation 7 (3-20) days vs. 25 (9-42) days p=0.005 ventilation (days; IQR).1

Average cost per day in the ICU for a patient receiving mechanical ventilation is $4,000.2

1. Thille A et al. Patient-ventilator asynchrony during assisted mechanical ventilation. Intensive Care Med. 2006;32:1512.

2. Dasta J et al. Daily cost of an intensive care unit day: the contribution of mechanical ventilation. Crit Care Med. 2005;33:1266-1271.

24% [ ]

18 days [ ]

$72,000 [ ]

PROBLEM: ASSOCIATED ASYNCHRONY COSTS

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Monitors patient’s demand breath by breath

Monitors compliance and resistance

Allows variable volume, flow, inspiratory time and pressure

Promotes natural breathing*

*Compared to VC, VC+ and PS

SOLUTION: PURITAN BENNETT™ PAV™*+ SOFTWARE

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Encourages use of the diaphragm1

Increases support as the patient’s demand increases

Improves patient-ventilator synchrony1,2

May help the clinician better manage a patient’s work of breathing3

1. Xirouchaki N. et al. Proportional assist ventilation with load-adjustable gain factors in critically ill patients: comparison with pressure support. Int Care Med. 2008;34(11):2026-2034.

2. Costa R. A physiologic comparison of proportional assist ventilation with load-adjustable gain factors (PAV+) versus pressure support ventilation (PSV) Intensive Care Med (2011) 37:1494–1500

3. Eumorfia Kondili, George Prinianakis, Christina Alexopoulou, Eleftheria Vakouti, Maria Klimathianaki, Dimitris Georgopoulos Respiratory Load compensation during mechanical ventilation-proportional assist ventilation with load-adjustable gain factors versus pressure support Intensive Care Med DOI 10.1007/s00134-006-0110-0

POTENTIAL BENEFITS OF PURITAN BENNETT™ PAV™*+ SOFTWARE

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Enter gender and height or predicted body weight (≥25 kg).

Touch:

Invasive vent type

SPONT mode

PAV™*+

Select % Support, PEEP and FiO2.

Select tube type.

Adjust the tube ID (6-10 mm ID).

Adjust the alarms.

PURITAN BENNETT™ PAV™*+ SOFTWARE SETUP

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↑PPEAK

↑VTI limit

↓VE or ↓VT

PURITAN BENNETT™ PAV™*+ SOFTWARE KEY ALARMS

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PA to PAV™*+ description

Default support starts at 70% Support

Two graphs and WOB bar

Enhanced calculation of compliance and resistance

PURITAN BENNETT™ PAV™*+ SOFTWARE CHANGES

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Measures values that create work

Assesses compliance and resistance (4 - 10 breaths with an automatic plateau)

Measures flow and volume every 5 msec

Uses the “equation of motion”

HOW PURITAN BENNETT™ PAV™*+ SOFTWARE WORKS: MEASUREMENTS

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% Support, PEEP and O2%

Tube size and type

Monitors:

Compliance, resistance and PEEPI

Work of breathing bar

WOBTOT and WOBPT

Elastic and resistance work

Estimated lung pressure shadow trace

Flow and volume waveforms

HOW PURITAN BENNETT™ PAV™*+ SOFTWARE WORKS: SETTINGS AND MONITORED PARAMETERS

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High inspired tidal volume (↑VTI)

High circuit pressure (↑PPEAK)

PAV STARTUP TOO LONG

PAV R&C NOT ASSESSED

Set all other traditional alarms

PURITAN BENNETT™ PAV™*+ SOFTWARE ALARM STRATEGY

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PAV™*+ software measures work variables.

The primary settings are % Support, PEEP and O2%.

The software amplifies patient efforts to offset the total work of breathing.

The software adjusts delivered pressure within the same breath.

The breath stops when patient inspiratory flow ceases.

Delivered pressure adjusts dynamically to patient effort.

SUMMARY OF HOW PURITAN BENNETT™ PAV™*+ SOFTWARE WORKS

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Capabilities

Intact respiratory drive

25 kg (55 lb.) or greater

6.0 I.D. tube or greater

Limitations

Apnea

Oversedation

Abnormal respiratory drive

Leaks

<25 kg (55 lb.)

Severe air trapping

Pneumatic nebulizer

Not available with NIV

CAPABILITIES AND LIMITATIONS

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TUBE COMPENSATION

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An endotracheal or tracheostomy tube can impose an increased work of breathing.1

Pressure Support limitations:

Fixed delivery pressure approach

T-Piece trials reduce the monitoring capabilities.

1. Maeda Y. Does the tube-compensation function of two modern mechanical ventilators provide effective work of breathing relief? Critical Care 2003, 7:R92-R97

PROBLEM: IMPOSED WOB FROM A TRACH OR AN ET TUBE

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Tube Compensation (TC) assists the patient in overcoming the flow resistance of the artificial airway.

TC software supports spontaneous breaths.

Only to the point of overcoming the artificial airways

TC may reduce the work of breathing.1

1. Maeda Y. Does the tube-compensation function of two modern mechanical ventilators provide effective work of breathing relief? Critical Care 2003, 7:R92-R97

SOLUTION: TUBE COMPENSATION (TC)

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Provide variable pressure with variable effort.

Reduce the imposed work associated with artificial airways.1

Allow for enhanced monitoring compared to the T-Piece approach.

1. Maeda Y. Does the tube-compensation function of two modern mechanical ventilators provide effective work of breathing relief? Critical Care 2003, 7:R92-R97

POTENTIAL BENEFITS OF TUBE COMPENSATION

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Select TC for spontaneous type.

In particular, mention:

% Support: 10% to 100%

Tube I.D.

Tube type

↑PPEAK

↑VTI

TUBE COMPENSATION SETUP

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Supports spontaneous breathing in SPONT, BiLevel and SIMV.

TC checks the flow rate every 5 ms.

TC uses flow, the % Support setting and a look-up table to determine delivered pressure.

% Support settings are from 10% to 100% (in 5% increments).

HOW TUBE COMPENSATION SOFTWARE WORKS

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↑PPEAK

↑Inspired tidal volume

All of typical alarms

TC-SPECIFIC ALARM STRATEGY

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Capabilities

Intact respiratory drive

7.0 kg (15.4 lb.) or greater

4.5 I.D. tube or bigger

Limitations

Oversedation

NeoMode <7.0 kg (15.4 lb.)

<4.5 I.D. tube

Apnea

CAPABILITIES AND LIMITATIONS

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VOLUME SUPPORT

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Pressure support does not provide a target tidal volume.

Pressure support does not down-regulate pressure automatically.

PROBLEM: LIMITATIONS OF PRESSURE SUPPORT

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Clinician can set a target tidal volume.

Automated pressure delivery is based on inspired volume.

VS provides variable flow.

SOLUTION: VOLUME SUPPORT (VS)

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Encourages the use of the diaphragm

Automatically decreases support pressure if target tidal volume is exceeded (1 – 3 cmH2O)

Increases pressure if the patient’s ability to take an adequate breath is compromised (1 – 3 cmH2O)

1. Sassoon C. Assist–Control Mechanical Ventilation Attenuates Ventilator-induced Diaphragmatic Dysfunction. Am J Respir Crit Care Med Vol 170. pp 626–632, 2004

POTENTIAL BENEFITS OF VOLUME SUPPORT

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Feature Volume Support Pressure Support

Lowest pressure for the set volume Yes No

Escalates if needed Yes No

Adjusts for changes in Raw and C Yes No

COMPARING VOLUME SUPPORT TO PRESSURE SUPPORT

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Select SPONT mode

Select VS for spontaneous type

Select:

VT SUPP

Trigger setting

Oxygen %

Rise %

ESENS

PEEP

↑VTI

↑PPEAK

VOLUME SUPPORT SETUP

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VS varies the inspiratory pressure to deliver the operator-set target tidal volume.

During VS, the inspiratory pressure target cannot be lower than PEEP + 1.5 cmH2O and cannot exceed the ↑PPEAK limit - 3 cmH2O.

Pressure adjust a max of +/- 3 cmH2O/breath if needed.

Test breath at startup. “VS startup” is displayed in the GUI’s prompt area.

HOW VOLUME SUPPORT SOFTWARE WORKS

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↑PPEAK limit (determines max target pressure)

Volume not delivered

↑VTI limit

VS-SPECIFIC ALARM STRATEGY

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Capabilities

Neonatal to adult

Spontaneously breathing patients

Invasive ventilation only

SPONT mode only

Limitations

Oversedation

Apnea

High effort may result in regulating of pressure down to undesirable levels.

Leaks without Leak Sync software enabled may result in regulating of pressure down.

NIV

CAPABILITIES AND LIMITATIONS

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PURITAN BENNETT™ NEOMODE 2.0 SOFTWARE

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Small tidal volume requirements

Ability to use AC and SIMV to ventilate with NIV

Auto-triggering and delayed cycling1

Management of nuisance alarms with CPAP

Reducing excessive oxygen exposure

Excessive tidal volume delivery

1. Oto J et al. A Comparison of Leak Compensation in Acute Care Ventilators During Noninvasive and Invasive Ventilation: A Lung Model Study Respir Care 013;58(12):2027–2037.

GENERAL PROBLEM

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Puritan Bennett™ Leak Sync software

A wide spectrum of modes both INV and NIV

Volume targeted availability down to 2.0 mL

Assist Control (VC, VC+ and PC)

SIMV (VC, VC+ - Dual Mode and PC)

BiLevel software

Spontaneous

Volume Support – Dual Mode

Pressure Support

Assist Control (VC, PC)

SIMV (VC, PC)

Spontaneous (PS)

CPAP

POTENTIAL SOLUTION: PURITAN BENNETT™ NEOMODE 2.0 SOFTWARE

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A NIV CPAP-specific mode with nuisance alarm management

A configurable temporary elevate oxygen feature

Enhanced monitoring of C20/C and mL/kg

POTENTIAL SOLUTION: PURITAN BENNETT™ NEOMODE 2.0 SOFTWARE

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One machine for all patient sizes

Possible reduced use of invasive ventilation

Automatic management of leaks

Reduced alarms in the NICU with NCPAP

Better management of oxygen exposure

Intended delivered volume managed by monitoring

C20/C

PBW/kg

POTENTIAL SOLUTION/BENEFITS OF PURITAN BENNETT™ NEOMODE 2.0 SOFTWARE

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Install the neonatal adapter door and the single patient use neonatal expiratory filter.

Connect a neonatal breathing circuit to the ventilator.

Select the neonatal breathing circuit type in Short Self-Test (SST).

Neonatal-specific settings and safety boundaries are activated.

PURITAN BENNETT™ NEOMODE 2.0 SOFTWARE SETUP

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Select actual patient weight

Range for neonates is 0.3 kg to 7.0 kg (0.66 lb. to 15 lb.)

Select INV or NIV and modes

Includes A/C, SIMV, Spont, BiLevel and CPAP

Breath type VC, VC+ or PC

All other specific settings

Configurable elevated FiO2

Leak Sync software automatically enabled

PURITAN BENNETT™ NEOMODE 2.0 SOFTWARE SETUP

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When in NeoMode 2.0 mode, if NIV CPAP is used:

VE TOT, VTE SPONT and ↑VTI alarms are not available.

VE and VTE displays are not available.

TA can be adjusted but defaults to off to avoid inadvertent alarms.

Adjust the DSENS alarm.

HOW NEOMODE 2.0 SOFTWARE WORKS: ALARM STRATEGIES IN CPAP

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Indications:

0.3 kg (0.66 lb.) and above

VT 2 mL and above

Neonatal breathing circuit

Neonatal adapter door and neonatal expiratory filter

Limitations:

Pediatric or adult breathing circuit

>7.0 kg (15 lb.) PBW

CAPABILITIES AND LIMITATIONS OF PURITAN BENNETT™ NEOMODE 2.0 SOFTWARE

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PURITAN BENNETT™ PROXIMAL FLOW SENSOR

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Circuit volume affecting graphs

Calibrations during ventilation

Water contamination of Proximal Flow Sensor

PROBLEMS: ACCURATE GRAPHICS AND PROXIMAL FLOW SENSOR ISSUES

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Measures flow and volume reflected at the patient wye

Displays both proximal flow and proximal pressure

Uses proximal flow values in the display of graphics.

Requires no manual calibration

Weight 6.6 g; dead space <1 mL

SOLUTION: PURITAN BENNETT™ PROXIMAL FLOW SENSOR AND MONITORING SOFTWARE

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Improved graphics for patient management

Improved patient data

POTENTIAL BENEFITS OF THE PURITAN BENNETT™ PROXIMAL FLOW SENSOR

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Proximal Flow Hardware

Proximal Flow Sensor

PURITAN BENNETT™ PROXIMAL FLOW OPTION COMPONENTS

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To disable or enable the Proximal Flow Option:

1. Touch the Configure wrench icon

2. Touch the Options tab

3. Touch the Prox tab

4. Touch the Enabled or Disabled button

5. Touch Accept

Periodic expiratory phase purging occurs regularly for accurate measurements.

PURITAN BENNETT™ PROXIMAL FLOW SENSOR SETUP: ENABLING/DISABLING THE SENSOR

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Installed during the SST (prompts are given)

Two connections:

Install monitoring end at the patient circuit wye

Install connector end on the ventilator’s front panel behind a clear door

Neonatal invasive ventilation only

PROXIMAL FLOW SENSOR SETUP WITH PURITAN BENNETT™ NEOMODE 2.0 SOFTWARE

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Alarms respond to values monitored with the flow sensor

Breaths are controlled from the internal flow sensors (prox flow values are for monitoring only)

Prox inoperative

PURITAN BENNETT™ PROXIMAL FLOW SENSOR SETUP: ALARM STRATEGY

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Measures flows, pressures and tidal volumes

Requires NeoMode 2.0 software option

Purge and auto-zero

Waveform Monitoring: PCIRCY

VY

VTY

Monitored data: VTIY

VTLY

VTEY

VTE SPONTY

VTE MANDY

VETOTY

LEAKY

HOW THE PURITAN BENNETT™ NEONATAL PROXIMAL FLOW SENSOR WORKS

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Patient + Circuit Patient

COMPARING THE VALUES FOR LEAK AND LEAKY

101 101 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

Page 102: THE PURITAN BENNETT™ 980 VENTILATOR · Puritan BennettTM 980 Series Ventilator Operator’s Manual Leak Sync Addendum Page B-2 2. Oto J et al. A Comparison of Leak Compensation

Capabilities

Measuring flows, pressures and tidal volumes of invasively ventilated neonatal patients

PBW of 0.3 kg (0.66 lb) to 7.0 kg (15.4 lb) using ET tube sizes from 2.5 mm to 4.0 mm

Limitations

Non-invasive (NIV)

Pediatric and adult

ET >4.0 mm

PBW >7.0 kg (15.4 lb)

Nebulized medications

CAPABILITIES AND LIMITATIONS

102 102 Puritan BennettTM 980 Ventilator Clinical Applications Lesson Plan | June 1, 2015

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