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Profile of Cervical Cancer in England: Incidence, Mortality and Survival 2012 (October)

Trends in incidence and mortality, England 1989 to 2010

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Page 1: Trends in incidence and mortality, England 1989 to 2010

Profile of Cervical Cancerin England:

Incidence, Mortality and Survival

2012 (October)

Page 2: Trends in incidence and mortality, England 1989 to 2010

Trends in incidence and mortality, England 1989 to 2010

Page 3: Trends in incidence and mortality, England 1989 to 2010

Funnel plot of incidence by SHA, 2005-2009

North East

North West

Yorkshire and The Humber

East Midlands

West Midlands

East of England

LondonSouth East Coast

6.0

7.0

8.0

9.0

10.0

11.0

12.0

0 1 1 2 2 3 3 4 4

ASIR

Rat

e pe

r 100

,000

Fem

ale

Popu

latio

n

Age Standardised Female Population (millions)

Data

Average

2SD limits

3SD limits

Page 4: Trends in incidence and mortality, England 1989 to 2010

Funnel plot of incidence by Cancer Network, 2005-2009

Avon, Somerset& Wiltshire East Midlands

Essex

Greater Midlands

Humber & Yorkshire Coast

Lancashire & South Cumbria

Merseyside & Cheshire

North East London

North London

North of England

North Trent

North West London

Pan Birmingham

South West London

Surrey, West Sussex & Hampshire

Sussex

Thames Valley

Yorkshire

5.0

6.0

7.0

8.0

9.0

10.0

11.0

12.0

13.0

14.0

15.0

0 1 2

ASIR

Rat

e pe

r 10

0,00

0 Fe

mal

e Po

pula

tion

Age Standardised Female Population (millions)

Data

Average

2SD limits

3SD limits

Page 5: Trends in incidence and mortality, England 1989 to 2010

Map of incidence by Cancer Network, 2005-2009

Page 6: Trends in incidence and mortality, England 1989 to 2010

Age-specific incidence rates and number of cases diagnosed by five year age group, England 2009

Page 7: Trends in incidence and mortality, England 1989 to 2010

Trends in incidence in women under 40, England 1989 to 2009

Page 8: Trends in incidence and mortality, England 1989 to 2010

Scatter plot of incidence against measure of deprivation by PCT, 2005-2009

0

2

4

6

8

10

12

14

16

18

20

0% 5% 10% 15% 20% 25% 30% 35% 40%

ASIR

PER

100

,000

fem

ale

popu

latio

n

Deprivation (proportion of people income deprived)

Page 9: Trends in incidence and mortality, England 1989 to 2010

Funnel plot of mortality by SHA, 2006-2010

North West

East of England

South East Coast

1.5

1.7

1.9

2.1

2.3

2.5

2.7

2.9

3.1

0 1 2 3 4 5 6 7

ASM

R pe

r 100

,000

Fem

ale

Popu

latio

n

Age Standardised Female Population (millions)

Data

England Average

2SD limits

3SD limits

Page 10: Trends in incidence and mortality, England 1989 to 2010

Funnel plot of mortality by Cancer Network, 2006-2010

Anglia

Greater Manchester & Cheshire

Humber & Yorkshire CoastMerseyside & Cheshire

South West London

Surrey, West Sussex & Hampshire

1.0

1.5

2.0

2.5

3.0

3.5

0 1 2 3

ASM

R pe

r 10

0,00

0 Fe

mal

e Po

pula

tion

Age Standardised Female Population (millions)

Data

England Average

2SD limits

3SD limits

Page 11: Trends in incidence and mortality, England 1989 to 2010

Map of mortality by Cancer Network, 2006-2010

Page 12: Trends in incidence and mortality, England 1989 to 2010

Age-specific mortality rates and number of deaths by five year age group, England 2008-2010

Page 13: Trends in incidence and mortality, England 1989 to 2010

Trends in mortality in women under 40, England 1988-1990 to 2008-2010

Page 14: Trends in incidence and mortality, England 1989 to 2010

Scatter plot of mortality against measure of deprivation by PCT, 2006-2010

0

1

2

3

4

5

6

0% 5% 10% 15% 20% 25% 30% 35% 40%

ASM

R pe

r 100

,000

fem

ale

popu

lati

on

Deprivation (proportion of people income deprived)

Page 15: Trends in incidence and mortality, England 1989 to 2010

Trends in one and five-year relative survival, England 1987-1989 to 2007-2009/2003-2005

Page 16: Trends in incidence and mortality, England 1989 to 2010

Funnel plot of one-year relative survival by Cancer Network, 2007-2009

75

80

85

90

95

0 100 200 300 400 500

% R

elati

ve S

urvi

val

Precision of Survival Estimate

Data

Average

2SD limits

3SD limits

Page 17: Trends in incidence and mortality, England 1989 to 2010

Funnel plot of five-year relative survival by Cancer Network, 2003-2005

Humber & Yorkshire Coast

50

55

60

65

70

75

80

85

0 100 200 300 400 500

% R

elati

ve S

urvi

val

Precision of Survival Estimate

Data

Average

2SD limits

3SD limits

Page 18: Trends in incidence and mortality, England 1989 to 2010

Age-specific relative survival, England 2007-2009 (one-year) and 2003-2005 (five-year)

Page 19: Trends in incidence and mortality, England 1989 to 2010

Trends in age-specific one-year relative survival, England 1987-1989 to 2007-2009

Page 20: Trends in incidence and mortality, England 1989 to 2010

Trends in age-specific five-year relative survival, England 1988-1990 to 2003-2005

Page 21: Trends in incidence and mortality, England 1989 to 2010

Relative survival by deprivation, England 2007-2009 (one-year) and 2003-2005 (five-year)

50

55

60

65

70

75

80

85

90

95

100

All Females 1 - Most Affluent

2 3 4 5 - Most Deprived

% R

elati

ve Su

rviv

al

One-year

Five-year

Page 22: Trends in incidence and mortality, England 1989 to 2010

Number of cases by morphology, England 1988-2009

0

500

1000

1500

2000

2500

3000

1988

1989

1990

1991

1992

1993

1994

1995

1996

1997

1998

1999

2000

2001

2002

2003

2004

2005

2006

2007

2008

2009

Year of Diagnosis

Squamous

Adenocarcinoma

Unclassified EpithelialAdenosquamous

Neuroendocrine

Other Epithelial

Other

Page 23: Trends in incidence and mortality, England 1989 to 2010

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

All Ages

20-24 25-29 30-34 35-39 40-44 45-49 50-54 55-59 60-64 65-69 70-74 75-79 80-84 85+

Squamous

Adenocarcinoma

Unclassified EpithelialAdenosquamous

Neuroendocrine

Other Epithelial

Other

Distribution of morphology by age group, England 2005-2009

Page 24: Trends in incidence and mortality, England 1989 to 2010

Distribution of morphology by deprivation, England 2005-2009

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Most Affluent

2 3 4 Most Deprived

Squamous

Adenocarcinoma

Unclass. Epithelial

Adenosquamous

Neuroendocrine

Other Epithelial

Other