Tumor Board: Multidisciplinary Approach to Rare Breast Lesions

Moderator: Aysegul A. Sahin, MD

Panelists:

Bruce Haffty

Kelly K. Hunt

Liane Philpotts

Kalliopi P. Siziopikou

Debu Tripathy

ASBD-SIS 2014 World Congress on Breast Healthcare

• 48-year old female presents with a palpable breast mass.

• She has a strong family history of breast cancer.

• Physical examination reveals a 2.5 cm mass, not fixed to overlying skin or underlying chest wall.

Case #1

Case #1

Courtesy of Dr. W. Yang

Case #1

Courtesy of Dr. W. Yang

Case #1

CNB reveals spindle cell malignant neoplasm

cytokeratin

Case #2

48-year old woman had a stereotactic CNB of pleomorphic calcifications identified on screening mammogram.

Case #2

Dx: Pleomorphic Lobular Carcinoma in situ

Case #2

E-cadherin

Case #2

Case #3

• 68-year old woman with history of myocardial infarct was found to have punctate calcifications associated with 1 cm left breast density on annual screening mammogram.

• Stereotactic CNB revealed invasive ductal carcinoma grade 2, ER+, PR+, Her2 -.

Case #3

• Segmental resection and SLN biopsy was performed.

• 1.1 cm IDC, grade 2, no LVI

• Margins free (closest margin 0.5 cm)