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1. What are the characteristics of microemulsions?
2. Why do we need to use homogenizers in the preparation of emulsion?
3. How can you identify the phase behaviour of microemulsion?
4. Different the methods of preparation of pharmaceutical emulsion.
5. How can microemulsion enhances to make a stable IV preparation?
6. Prophylactic antibiotic treatment is used to minimise the risk of endocarditis in patients with hypertrophic cardiomyopathy. Your team have been asked to formulate a new
microemulsion oral drug formulation for clindamycin hydrochloride that can maintain therapeutic drug levels form 6-8 hours. You have been ask by the company to have justification of your decision for formulating it into microemulsion with other formulation scientists in your organisation.
i. How can microemulsion increase the stability and effectiveness of the formulated drug as oral medication? Explain your answer
ii. What are the stability test necessary for the development of oral microemulsion dosage form?