TWICE MONTHLY BIBLIOGRAPHY ON PROSTAGLANDINS - BIOLOGY - LATE JUNE PREPARED BY SHEFFIELD UNIVERSITY, BIOMEDICAL INFORMATlON SERVICE

SHEFFIELD SlO 2TN

1. BOOKS, REVIEWS, SYMPOSIA Armour CL, Black JL (Eels) Alan R. Liss Inc, 1988, 447 pages, ISBN 0 8451 5113 4, S84JJO Hardbound Mechanisms in Asthma. Pharmacology, Physiology, and Management. Progress in Clinical and Biological Research, Vol.263. Satellite Symp on Asthma at the 10th Intar- national Congress of Pharmacology (Air- ways 87), Ayers Rock, Australia, August 3@ September 2, 1987. Includes ssctions on:- pole of eicosanoids in airway smooth muscle tone. Effect of PAF-a&her in non-human primates.

J CEL.L BIOCHEM 1988, Suppl 12E 32-113 UCLA Symposia on Molecular and Cellular Biology Cell Activation and Signal Initia- tion: Receptor and Phospholipasa control of lnositol Phosphate, PAF and Eicosanoid Production.

Gittenbergerdegroct AC, Strengers JLM// Rijksuniv Leiden, Dept Anat & Embtyol, Anat Embryo1 Lab, Wassenaaseweg 62. Postbus 9602,23CQ RC L&den. Netherlands INT J CARDIOL 1988, 19 (2) 153 Histopathology of the arterial duct (Ductus arteriosus) with and without treatment with prostaglandin-El (Review)

Braquet P. Mangold HK, Vargaftif BB (Eds). S Karger AG, 1988, 1% Pp, ISBN ISBN: 3-no554669-6, $1 IO.WSFR 165.WDM 198.00 Hardbound Biologically Active Ether Lipids - Progress in Biochemical Pharmacology, Vol 22. Includes chapters on:- PAP m cellular im- munology: Platelet-activating factor and the cardiovascular system _ involvement in car- diac anaphylaxis

Banner G. Carretero OA, Kuppers H, McGtff JC (Eds)// Birkhauser Vedag AG, 1987, 390 pages, sfr SE.--. ISBN: 3-7643-1922- 4 (Basel); O-8176-1922-4 (Boston) Vasodepressor Hormones in Hypetten- sion: Prostaglandins and Kallikrein-Kinins: This volume is a compilation of material that was presented at a satellite sympostum to the 1986 Meeting of the International Society of Hypertension. The Symposium addresses hy- pertension from the point of view of vascdepressor hormones, rather than the more usual one of supposition that the many and various vascconstrictor / vasopressor sys-

terns are primaty agents. The book is ar- ranged between 23 chapters nominally con- cerned with “Prostaglandins” and 17 with the “Kallikrem-hinm System”; the division is not of course absolute, as there k interdepen- dence between these two systems, as well as with other factors such as atrial natnuretic peptide and the renin-angtotensin system. in

both normal cardwascular homeostasis and in hypertension. In this context the so-called angiotensin I converting enzyme or kmmase II and its tnhibitols receive welcome, detailed and critical attention.

There are a number of chapters that identify the interrelationships of the vasodepressor agents, and hypotheses are presented that highlight areas for future study. For example, the argument that circulating materials. pos- sibly of renal origin such as kinins. pros- taglandins and hypotensive liplds. may have

systemic roles, as opposed to purely in- tt-arenal actions, is well aired, although the controvemy cannot in reality be said to be resolved. In addition there are some faseinat- ing observations that touch upon the ccm- plex physiological and pathological interplay behveen renal dopamine, atrial natriuretic factor, calcium inactive and active renin, ksl- likrein, angiotensin I convening enzyme and dietary factors. Each chapter is well referenced and this volume, as well as being an up-to-date analysis and critique of the field, IS an excel- lent literature source. In summary this book contains material that is relevant to the physiology, pharmacology, bioehemistty, cell biology and molecular biology of hyperten- sion. A minor adverse comment may be levelled at the standard of reproduction with some of the figures being less than crystal clear, and there are rather mere typographic errors than one might expect from a volume that contains so many excellent chapters. These latter comments are in a sense ex- cusable, since the editors and pubhshen clearly wished to achteve speedy publication of a symposium in an area that is advancing so rapidly. Review by Pmf I Henderson, Dept Anim Biol. Univ Sheflield

2. GENERAL Rock JA et al// CONTRJB GYNECOL OBSTEI 1987, 16 13843 Fluid volume and prostanoid concentra- tion during the proliferative and periovulatory phase of the menstrual cycle (19 ref)

3. PROSTAGLANDINS E AND F Nakhla AM// Columbia Univ, Ccl1 Phys & Surg, St Lukes Roosevelt Hosp Ctr. Dept Med, New York, NY 10019, USA LIFE SC1 198J3,42 (21) 2155 Calcitonin stimulates adenylate cyclasa ac- tivity, the accumulation of cyclic adenosine 3’,5’ monophosphate and the releasa of prostaglandin E2 in rat intes- tinal mucosa.

Venkovs K, Radomimv R/f Bulgarian Acad Sei. Inst Physiol, Dept Exptl Pharmacol, BU- 1113 Sofia, Bulgaria PHARMACOL RES COMMUN 1988, 20 (4) 277 Contractile responses of isolated guinea- pig vas deferens to trains of electrical stimuli and influence of prostaglandin E2.

Brinks GJ, Dapper JH, P’rederick M, Eg berink J, Kwee B/I Organon Sri Dev Grp, Pharmaceut Res & Dev Lab. Oss, Nether- lands DRUG DEVELOP IND PHARM 1988, 14 (4) 489 Formulation of a concentrated dispersion as a carrier for the delivery of prostaglan- din E2 in the cervical canal.

Jivegard L, Thune A, Svanvik J/i Sahlgrcrts Hasp, Dept Surg 1, S 41345 Gothenburg, Sweden ACTA PHYSIOL. SCAND 1988. 132 (4) 549

lntraluminal prostaglandin E2 affects a gallbladder function by activation of in- tramural nerves in the anaesthetized cat.

Pate JL, Nephew KP// Ohio State Univ. Dept Daily Sei, Columbus, Oh 43210, USA BIOL REPROD 1988,38 (3) 568 Effects of in vivo and in vitro administra- tion of prostaglandin FPalpha on lipoprotein utilization in cultured bovine luteal cells.

Jespetsen B, Pedersen EB, Madsen M. Chris- tensen P. Eiskjar H, Leyssac PP, Sorensen SS// Aarhus Univ, Asrhus Kommune Hasp, Dept Med C, DK-8000 Asthus C. Denmark EUR J CLIN INVEST 1988. 18 (2) 202 Disturbed relationship between urinary prostaglandin E2 excretion, plasma ar- ginine vasopressin and renal water excre- tion after oral water loading in early hepatic cirrhosis.

Panosysn AG, Dadayan MA, Gabnelyan ES// Minist Publ Hlth ARSSR, Med Radio1 Res Inst, Erevan, Armenia, USSR BULL EXP BIOL MED-ENGL TR 1987. 104 (10) 1417 Cucurbitacin R gluccside as a regulator of steroid and prostaglandin E2 production and specific modulator of the hypothalamohypophyseo-adrenocortical system.

Richards D, Rutherford RB// Univ Connec- ticut, Sch Dent Med, Dept Periodontoi, Far- mington, Ct 06032, USA ARCH ORAL BlOL 1988.33 (4) 237 The effects of interleukin-1 on col- lagenolytic activity and prostaglandin-E secretion by human periodontal-ligament and gingival fibroblast.

Rand J, Dahlen SE, Sydbom A, Lindbom 1.. Hedqvist P/i Kamlinskn Inst. Dcpt Physiol. S- 10401 Stockholm, Sweden PROC NATL ACAD SC1 1988.85 (7) 2315 Enhancement of acute allergic inflamma- tion by indomethacin is reversed by pros- taglandin E2: Apparent correlation with in vivo modulation of mediator release.

Hahlin M, Dennefors B, Johanson C, Ham- berger U/ Gothenburg Univ. Dept Obstet bt Gynecol, W1345 Gothenburg, Sweden J CLlN ENDOCRINOL METAB 1988. 66 (5) 909 Luteotropic effects of prostaglandin E2 on the human corpus luteum of the menstrual cycle and of early pregnancy

Flach AJ, Eliason JA// Vet Adm Med Ctr, Div Ophthalmol, 4150 Clement. 112A Mailstop, San Francisco, Ca 94121, USA J OCUL PHARMACOL 1988.4 (I) 13 Topical prostaglandin E2 effects on nor- mal human intraocular pressure.

Bhasker KR, Bamea A’// * tintv Texas, Hlth Sci Ctr, Dept Obstct & Gynecol, 5323 Harry Hines Blvd, Dallas, TX 75235, USA ENDOCRINOLOGY 1988,122 (5) 2143 Progesterone augments ccpper-pros- taglandin E2 stimulation of the releass of gonadotropin-releasing hormone from ex- plants of the median eminence of imma-

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ture female rats: An estrogen-dependent process.

Srngh M. Madan MU/ Nat1 Dairy Res Inst, Div Dairy Cattle Physiol, Kamal 132001, Haxysna, India INDIAN J ANIM XI 1988,58 (4) 424 Postpartum prostaglandin-F (PGF) levels and short-term variations during oestrus in buffaloes.

Soycola E, Verona OP*// *Tuskegee Univ, Sch Vet Mcd, Dcpt Physiol & Pharmacol, Tuskegee, Al 36088, USA THERIOGENOLOGY 1988,29 (4) 791 In vitro release of PGRalpha from the caprine uterus and the effect of ovarian steroids.

Okuda K, Gaonna WA, Sam K// Obihiro Univ Agr & Vet Med, Dept Vet Obstet & Gynecol, Obihiro, Hokkaido 080, Japan THERIOGENOLOGY 1988,29 (4) 823 Effects of gonadotropin releasing hor- mone and prostaglandin F2alpha on the reproductive performance in postpartum COWS.

Meinen K, Lange R, Breinl H// St Lukas Klin, Gyn Geb Abt, D 5650 Solingn 1, W Germany GEBURTSH FRAUENHEILK 1988,48 (4) 268 lntramyometrical application of PGF2alpha in the management of severe atonic haemorrhage (German)

4. PRECUFSORS Ito Y, Barcelli U’, Yamashita W, Weiss M ( Glasgreenwalt P, Pollak VE// *Univ Cincin- nati, Med Ctr. Depr Med, Div Nephml, 5363 MSB, 231 Bethesda Ave, Cincinnati, Oh 45267, USA METABOLISM 1988,37 (4) 352 Fish oil has beneficial effects on lipids and renal disease of nephrotic rats.

Rustemeijer C, Bile HJG, Beukhof J& Schouten JA, Mulder C, Danker AJM// Free Univ Amsterdam Hasp, Dept Internal Med, POB 7057, 1007 MB AmrIerdam, Nether- lands CURR THER RFiS 1988,43 (4) 559 The effect of fish oil mnoentrate on serum lipids and lipoproteins in patients on main- tenance hemodialysis.

Miranda JA, Herruzo AJ’, Montoyz F, Huete A, Mallol MC, Delaorden AF// ‘Vir- gen Nieves Reg Hasp, Dept Obstetr & Gynecol, Ave Constitut 100, E 18014 Granada, Spain INT J GYNAECOL OBSTEI 1988, 26 (2) 209 Induction of deed fetus labor with 15-(S)- methyl prostaglandin F2alpha.

5. Arachidooic Acid Ohtsuka T, Ozawa M, Katayama T, lshibashi S// Hiroshima Univ, Sch Med. Dept Physiol Chem, Minami ku. Hiroshima 734, Japan ARCH BIOCHEM BIOPHYS 1988. 262 (2) 416

Synergism of phosphorylation of 45K oroteinlsl and araohidonate release in the induotidn of superoxide anion production in guinea pi9 polymorphonuclear leukocytes.

Lagente V, Desquand S, Hadvary P, Cirino M, Lellouch-Tubiana A, Lefon J, Vargaftig BB// INSERM, U285, Inst Pasteur, Unite Pharmacol Cellulaire, 25 Rue Dr Roux, F- 75015 Paris, France BRIT J PHARMACOL 1988,94 (1) 27 Interference of the Paf antagonist Ro lg- 3704 with Paf and antigen-induced broncho-constriction in the guinea pig.

Evans ‘IW, Dent G, Rogers DF, Aursudkij B, Chung KF, Barnes PJ*// ‘Brompton Hosp, lnst Cardiothorac, Dept Clin Phar- macol, Fulham Rd. London SW3 6HP, England BRIT J PHARMACOL 1988,94 (1) 164 Effect of Paf antagonist, WEB 2086, on air- way microvascular leakage in the guinea- pig and platelet aggregation in man.

Robertson DA, Wang DY, Lee CO, Levi R*// ‘Cornell Univ, Med Ctr, Coil Med, Deut Pharmacol. IMO York Ave. New York. NY‘ 10021, USA J PHARMACOL EXP THER 1988, 245 (1) 124 Negative inotropic effect of platelet-activat- ing factor - Association with a decrease in intracellular sodium activity.

Willuweit B, Aktories K’// ‘Univ Giessen Klinikum, Rudolf Buchheim Inst Pharmakol, Frankfurter Str 107, D-6300 Giessen, W Ger- many NAUNYN-SCHMIED ARCH PHAR- MACOL 1988.337 (3) 354 Heparin and heparinoids impair adrenaline and platelet-activating factor but not thrombin-induced inhibition of adenylate cyclase and stimulation of GTP hydrolysis in human platelet membranes.

Valone FH// Vet Adm Med Ctr, Dept Med, San Francisco, Ca 94121, USA THROMB RES 1988,50 (1) 103 Platelet-activating factor binding and meta- bolism during human platelet aggregation.

Holub BJ, Celi B, Skeaff CM// Univ Guelph, Dept Nutr Sci, Guelph, Ontano, Canada NlG 2Wl THROMB RES 1988,50 (1) 135 The alkenylacyl class of ethanolamine phospholipid represents a major form of eimsapentaenoic acid (EPA)-containing phospholipid in the platelets of human subjects consuming a fish oil concentrate.

Pimtzhy E, Colliez P. Guilmard C, Schaever- beke J, Mencia-Huerta JM. Braquet P// Inst Henri Beaufour, Za Courtaboeuf, 72 Ave Tmp, F 91952 Les Ulis, France BRJT J EXP PATHOL 1988,69 (2) 291 Protection of platelet-activating factor-in- duced acute renal failure by BN 52021.

Dadd RH. Kleinjan JE, Asman SM// Univ Calif Berkeley, Div Entomol & Parasitol, Berkeley, Ca 94720, USA ENVIRON ENTOMOL 196817 (2) 172 Eicosapentaenoic acid in mosquito tis- sues: Differences between wild and laboratory-reared adults.

Clark RM, Hundreiser KFZl/ Univ Connec- ticut, Dept Nutr Sci, Stem. Ct 06268, USA J PEDIAT GASTROENIEROL NUTR 1%X8,7 (3) 469 Correlation between changes in the mn- centrations of linoleate and arachidonate in human milk (Letter)

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Specker BL. Wey HE, Miller Dll Umv Cin- cinatti, Med Ctr, Dept Pediat, Div Neonatal. Cincinatti, Oh 45267, USA J PEDIAT GASTROENTEROL NUTR 1988, 7 (3) 470 Author’s Reply.

Tokumura A, Terao M, Okamoto M. Yoshida K, Tsukatani W/ Univ Tokushima, Fat Pharmaceut Sci, l-78-1 Shomachi, Tokushima 770, Japan EUR J PHARMACOL 1988,148 (3) 353 Study of platelet activating factor and its antagonists on rat colon strip with a new method avoiding tachyphylaxis.

Bachelet M, Adolfs MJP, Masliah J, Bcreziat G, Vargaftig BB, Bonta IU/ Inst Pasteur, IN- SERM. lJ2E5. 25 Rue Dr Roux, F-75724 Paris 15, France EUR J PHARMACOL 1988,149 (1-2) 73 Interaction between PAF-acether and drugs that stimulate cyclic AMP in guinea- pig alveolar macrophages.

Martins MA, Martins PMRS, Neto HCCF, Bozza FT, Dias PMFL, Cordeim RSB’. Var- gaftig BB// l lnst Oswald0 Cruz, Depr Fis & Farmacodinam. Aw Bras& C&a Postal 926, BR-4365 Rio de Janeiro, Brazil EUR J PHARMACOL 1988, 149 (1-2) 89 Intravenous injections of PAF-acether in- duce platelet aggregation in rats.

Susplugastaillade C. Susplugas P, Michel FN Fat Pharm Montpellier, Pharmacognosie Lab, 15 Ave Charles Flahault, F-34060 Montpellier, France PHARM ACTA HELV 1988,63 (2) 59 Anti-inflammatory activity of’ Reseda phyteuma L. ether-extract - effects on arachidonic-acid metabolism (German)

Bazan HEP// Lxxisiana State Univ, Med Ctr, Ctr Eye, 2020 Gravier St, Suite E, New Or- leans, La 70112, USA J OCUL PHARMACOL 1988,4 (1) 43 Effects of lipoxygenase inhibitors on the arachidonic acid cascade in the rabbit cor- nea after injury.

Rola-Pleszczynski M, Pouliot C, Turcolte S. Pignol B, Braquet P, Bouvrette I.// Univ Sherbrooke, Fat Med, Dept Pediat, Div Im- munol, 3001 N 12th Ave, Sherbrooke, Quebec, Canada JlH 5N4 J IMMUNOL 1988.140 (10) 3547 Immune regulation by platelet-activating factor. I. Induction of suooressor ~811 ac- tivity in human monocytes and GD8+ T cells and of helper cell activity in CD4+ T cells.

Worthen GS, Seccombe JF, Clay KL, Guthrie LA, Johnston RB// Nat1 Jewish Ctr Immunol L Resp Med, Dept Med, 1400 Jack- son St, Denver, Co 80206, USA J IMMUNOL 1988, 140 (10) 3553 The priming of neutrophils by lipopclysac- charide for oroduction of intracellular platelet-activat/ng factor: Potential- role in mediation of enhanced superoxide secfe- tlon.

Vivier E, Salem P, Dulioust A, Prascuth D. Metczeau P, Benveniste J, ?homas Y’// l Univ Paris Sud, INSERM. U2Do. 32 Rue Camets. F-92140 Clamart, France EUR J IMMUNOL 1988,18 (3) 42.5 Immunoregulatory functions of PAF- acether. 2. Decrease of CD2 and CD3 an- tigen expresslon.

McGee R, Sansom MSP. Usherwood PNIUI Med Coil Ohio. Dept Pharmacol, CS 10008, Toledo, Oh 43699, USA J MEMBRANE BIOL 1988,102 (1) 21 Characterization of a delayed rectifier K+ channel in NGlC#-15 neuroblastoma X glioma cells: Gating kinetics and the ef- fects of enrichment of membrane phos- pholipids with arachidonic acid.

Baba Y, Morita I’, Susami T, Kurcda T, Murota S-I// *Tokyo Med & Dent Univ. Fat Dent, lnst Stomatognath Sci, l-545 Yushima. Bunkyo ku, Tokyo 113. Japan BIOCHIM BIOPHYS ACTA 1988, 960 (1) 67 Comparison of arachidonic acid metabo- lism between myofibroblasts and fibroblasts isolated from rat palatal mucoperiosteum.

Yanoshita R, Kudo 1. lkizawa K. Chang HW, Kobayashi S, Ohno M, Nojima S, Inoue K // Univ Tokyo, Fat Phannaceut Sci, Bunkyo ku, Tokyo llj, Japan J BIOCHEM TOKYO 1988,103 (5) 815 Hydrolysis of platelet activating factor and its methylated analogs by acetyl- hydrolases.

Kroegel C// Univ London, Bmmpton Hosp. lnsr Cardiothorac. Deot Clin Pharmcol. Ful- ham Rd, London iW3’6HP, England KLIN WOCHENSCHR 198& 66 (9) 373 The potential pathophysiological role of platelet-activating factor in human dis- eases.

Katusic ‘ZS, Shepherd JT, Vanhoutte PM’// *Mayo Clin & Mayo Fdn, Dept Phyaiol & Biophys, Rochester, Mn 55905, USA SROKE 1988,19 (4) 476 Endotheliumdependent contractions to calcium ionophore A23187, arachidonic acid, and acetylcholine in canine basilar arteries.

Jie MSFLK Lao HB. Zheng YFII Univ Hong Kong, Dept Chem. Pokfulam Rd, Hong Kong, Hong Kong J AMER OIL CHEM SOC 1988,65 (4) 597 Lipids in chiness medicine. Characteriza- tion of all cis 5,11,14, 17-eicosatetraenoic acid in Biota orientallis seed oil and a study of oxo/furanoid esters derived from Biota oil.

6. Leukotrienes Phan SH, McGarry BM, Loeffler KM, Kunkel SUI Univ Michigan, Seh Med. Dept Pathol, Box 0602. 1301 Catherine St, Ann Arbor. Mi 48109, USA BIOCHEMISTRY-USA 1988,27 (8) 2846 Binding of leukotriens C4 to rat lung fibroblasts and stimulation of collagen syn- thesis in vitro.

Hamasaki T. Sakano T, Kobayashi M, Sakura N, Usui T, Ueda K// Huoshima Univ, Sch Med, Dept Pediat. Kasumi l-3-3, Minami ku, Hiroshima 734, Japan CLIN CHIM ACTA 1988, 173 (2) 235 Impaired production of leukotrienes by peripheral blood polymorphonuclear leukocytes from children with chronic renal failure (Letter)

Barcelli UO. Beach DC, Pollak VE// Univ Cincinnati, Med Ctr, Dept Internal Med. Div Nephml. 5363 MSB. 231 Bethesda Ave, Cin- cinnati. Oh 45267, USA

LIPIDS 1988.23 (4) 309 The influence of n-6 and n-3 fatty acids on kidney phospholipid composition and on eicosanoid production in aging rats.

Ingram CD, Brash AR*// *Vanderbilt Univ, Med Ctr, Seh Med, Dept Pharmacol, Div Clin Phannaeol, Nashville, Tn 37232, USA LIPIDS 1988,23 (4) 340 Characterization of HETEs and related con- jugated dienes by UV spectroscopy.

Snyder DW, Liberate NJ, McCarthy MM/f Eli Lilly & Co, Lilly Res Lab, Pulm Res Grp, Indianapolis, In 46285, USA J PHARMACOL METHODS 1988, 19 (3) 219 Conscious guinea-pig aeroml model for evaluation of peptide leukotriene an- tagonists.

Secrest RJ, Ohlstein EH, Chapnick BM’II *St Louis Univ, Sch Med. Dept Phannacol, 1402 S Grand Blvd, Sr Louis, MO 63104, USA J PHARMACOL EXP THER 1988, 245 (1) 47 Relationship between LTD4-induced en- dotheliumdependent vasomotor relaxa- tion and cGMP.

Hisayama T, Takayanagi I’, Nakazato F. Hirano K/i ‘Toho Univ, Sch Phannaceut Sci, Dept Chem Pharmacol, 2-2-l Miyama, Funabashi, Chiba 274, Japan NAUNYN-SCHMlED ARCH PHAR- MACOL 1988,337 (3) 2% Epithelium selectively controls hypersen- sitization of the response of smooth muscle to leukotriene D4 by endogenous prostanoid(s) in guinea-pig trachea.

Mita H, Yui Y, Yasueda H, Shida T/l Nat1 Sagamihara Hasp, Clin Res Ctr Rheumatoal- lergol, 8-l Sakuradai, Sagamihara, Kanagawa 228, Japan INT ARCH ALLERGY APPL IMMUNOL 1988,85 ( 4) 422 Effect of deuterium oxide on leukotriene C4 generation in immunologically stimu- lated human leukocytes.

Ahmed T, D’Bmt J. Wasserman M. Muccitel- Ii R, Robinson M. Tucker S, Marchetre B// Univ Miami, Mt Sinai Med Ctr, Sch Med, Div Pulm Dis. Miami Beach, R 33140. USA 3 APPL, PHYSIOL 1988,64 (4) 1700 Effect of verapamil on pulmonary and eicosanoid responses to endotoxin in awake sheep.

Sakagami Y/l NIPPON SHOKAKIBYO GAKKAI ZAS- SHI 1987 AUG, 84 (8) 1702 Synthesis of leukotriene 84 by rat Kupffer cells (Japanese)

Mahauthaman R, Howell Cl. Spur BW. Youl- ten LIF, Clark TJH, Lessof MH. Lee TH*// ‘Guys Hwp, United Med & Dent Sch Guys & St Thomass Hosp. Dept Med, London SE1 9RT, England J ALLERG CLIN IMMUNOL 1988, 81 (4) 6% The generation and cellular distribution of leukotrieneC4 in human eosinophils stimulated by unopsonized zymosan and glucan particles.

Lam S, Chan H, Leriche JC. Chanyeung IM. Salari H// Univ British Columbia, Vancouver Gen Hasp, Dept Med, Ulv Resp, 2775 Heather St, Vancouver. BC, Canada VSZ 3.15

820

J ALLERG CLIN IMMUNOL 1988.81 (4) 711 Release of leukotrienes in patients with bronchial asthma.

Albazzaz MK, Pate1 KR*// *Western Infirm, Depr Resp Med, Glasgow Gil 6NT, Scotland THORAX 1988,43 (4) 306-11 Effect of azelastine on bronchoconstriction induced by histamine and Ieukotriene C4 in patients with extrlnslc asthma.

Chegini N, Rae CV’// ‘Univ Louisville. Ctr Hlth Sei, Sch Med, Dept Obstet & Gynecol. 438 MDR Bldg, Louisville, Ky 40292, USA ENDOCRINOLOGY 1988,122 (5) 1732 Quantitative light microscopic autoradiographic study on [SH]leukotriene C4 binding to nonpregnant bovine uterine tissue.

Mene P, Dunn MJ’// ‘Univ Hasp Cleveland, Dept Med, Div Nephrol, 2074 Abington Rd. Cleveland, Oh 44106, USA CIRC RES 1988,62 (5) 916 Eicosanoids and control of mesangial cell contraction.

Secrest RJ, Chapnick BM*// *St Louis Umv. Seh Med, Dept Pharmacol, 1402 S Grand Blvd. St Louis, MO 63104, USA CIRC RJZS 1988,62 (5) 983 Endothelialdependent relaxation induced by leukotrienes C4, 04, and E4 in isolated canine arteries.

Gut J, Trudell JR*. Jamleson GCII ‘Stan- ford Univ. Med Ctr, Seh Med, Dept Anes- thesia, Stanford, Ca 94305, USA BIOMED ENVIRON MASS SPECIROM 1988, 15 (9 ) 509 Leukotriene biosynthesis: Direct chemical ionization mass spectrometry of under- ivatized arachidonic acid metabolites.

Rooney SA, Gobran LIII Yale Univ. Sch Med. Dept Pediat. Div Perinatal Med. POB 3333, New Haven, Ct 06510, USA BIOCHIM BIOPHYS ACI‘A 1988. 960 (1) 98 Adenosine and leukotrienes have a regulatory role in lung surfactant secretion in the newborn rabbit.

Ophir D. Fink A, Eliraz A. Tabachnik E. Benrwich z// Kaplan Hasp, Dept Otolaryn- gol, IL 76100 Rehovot. Israel ARCH OTOLAR-HEAD NECK SURGERY 1988. 114 (5) 522 Allergen-induced leukotriene production of nasal mucosa and peripheral blood leukocytes.

7. Rostacyclin Voss BL, Hamilton KK. Samara ENS, McKee PA// Univ Oklahoma, Hlth Sci Ctr, Dept Uml, POB 26901, 5SP330. Oklahoma City, Ok 73190, USA TRANSPLANTATION 1988,45 (4) 793 Cyclosporine suppression of endothelial prostacyclin generation: A possible mechanism for nephrotoxicity.

Hardy CC, Braddinl! P. Robinson C. Holeate Sl’// -Southampton ?ien Hasp, Southam&n SO9 4XY, England J APPL PHYSIOL 1988,64 (4) 1567 Bronchooonstrictor and an- tibronchoconstrictor properties of inhaled prostacyclin in asthma.

Aitokalliotallberg AM, Viinikka LU, Ylikorkala RO’// l Univ Helsinki, Depr Obstet & Gynecol, Haartmaninakatu 2, SF M)29O Helsinki 29, Finland CANCER RES 1988,48 (9) 2396 Increased synthesis of prostacyclin and thromboxane in human ovarian malignan-

CY.

Rustin MHA, Bull HA, Machin SI. Isenberg DA, Snaith ML, Dowd PM// Middlesex Hasp, Depr Dermatol. Mortimer St. London WlN ?AA, England J INVEST DERMATOL 1988. W (5) 744 Effects of the lupus anticoagulent in patients with systemic lupus erythematosus on endothelial cell pros- tacyclin release and procoagulant activity.

Goerg KJ. Wanitschke R Becker U, Meyer zum Buschenfelde KH// Univ Maim, Depr Inrernal Med 1. Med Clin 1, Langenbeckstr 1, D-6.500 Maim, W Germany EUR J CLIN INVEST 19% 18 (2) 124 Effect of the stable prostacyclin analogue iloprost on water and electrolyte transfer of the rat ileum and colin in vivo.

Virgolini I// Vienna LJalv, Med 2 Klin, Nuke Med Abr, Gamisongasse 13, A 1090 Vienna, Austria WIEN KLIN WOCHENSCHR 1988, 100 (7) 216 Identification of high-affinity PGl2 binding sites in human thyroid gland (German)

Wollersheim H. Thien TN Univ Hosp St Rad- boud, Dept Med. DIV Cien Internal Med, Geen Grootpl Zuid 8, POB 9101, 6.500 HB Nijmegen, Netherlands ANGlOLOGY 1988.39 (3) Pt I, 227 Hemodynamic effects of prostacyclin in- fusions in healthy volunteers.

de Nucci G, Gryglewski RJ, Warner ‘ID, Vane JR# William Harvey Res Inst, St Bar- tholomews Hosp Med Coil, Charterhouse Sq. Iundon EClM 6BQ, England PROC NATL ACAD SC1 1988,85 (7) 2334 Receptor-mediated release of endothelium- derived relaxing factor and prostacyclin from bovine aortic endothelial cells is coupled.

El Tahir KEH, Hamad EA, Ageel AM, Nasif MAA, Gadksrim EA// King Saud Univ, Coil Pharm. Dept Pharmacol, POB 2457, Riyadh 11451, Saudi Arabia ARCH INr PHARMACODYN THER 1988,292 (MAR ) 182 Effects of sesame and cod liver oils on prostacyclin synthesis by the rat thoracic aorta.

Steel SA. Pearce JM// St Georges Hosp. Sch Med. Dept Obstet & Gynaecol, Fetal Wel- fare Lab, London SWl7, England J ROY SOC MED 1988,81 (4) 214 Specific therapy in severe fetal intrauterine growth retardation: failure of prostacyclin.

Windeck R, Brodde OE// Univ &en, Gesamthsch Klinikum, Med Klin & Poliklin. KIin Endokrinol Abt, Hufelandstr 55, D-4300 Lessen 1. W Germany MED KLIN 1988,83 (8-9) 289 Stimulation of renin-aldosterone-system

by infusion of prostacyclin in hyporeninemic hypoaldosteronism (Ger- man)

8. Tbromboxanes Kaufman RP. Klausner JM. Anner H, Fein- gold H, Kobzik L, Valeri CR, Shepro D, Hechtman HB’II *Brigham & Womens Hosp. Depr Surg, 75 Francis St, Boston, Ma 02115. USA J TRAUMA 1988,28 (4) 458 Inhibition of thromboxane (TX) synthesis by free radical scavengers.

Jacobs TP et al// CENT NERV SYST TRAUMA 1987. 4 (2) 95-118 Thromboxane and 5HETE increase after experimental spinal cord injury in rabbits.

MaIs DE, DeHoll D, Sightler H, Halushka PV// Med Univ S Carolina, Dept Cell & Molec Phannacol & Exptl Therapeut, 171 Ashley Ave, Charleston, SC 29425, USA EUR J PHARMACOL 1988,148 (3) 309 Different pharmacologic activities for 13- azapinane thromboxane AZ analogs in platelets and blood vessels.

Lim LK, Khirabadi BS, Braquet P, Ramwell PW, Foegh ML*// *Georgetown Univ Hasp, Dept Surg, Div Transplantat. Washington, DC 2ooO7, USA TRANSPLANT PROC 1988,20 (2) 254 Effect of the Blipoxygenase inhibitors EP 10045 and EP 10161 on cardiac graft cel- lular infiltrate and thromboxane formation.

Lim LK Alijani MR Helfrich GB, Foegh ML*// ‘Georgetown Umv Hosp. Dept Surg, Div Transplantat, Washington, DC 2ooO7. USA TRANSPLANT PROC 1988,20 (2) 258 Correlation of renal inflammatory cell in- filtrate with thromboxane.

Morel DR Lcwenstein E, Nguyenduy T, Robinson DR, Repine JE, Chenoweth DE, Zapol WM*// ‘Massachusetts Gen Hosp, Dept Anesthesia. Boston, Ma 02114, USA CIRC FiES 1988.62 (5) 905 Acute pulmonary vasoconstriction and thromboxane release during protamine reversal of heparin anticoagulation in awake sheep. Evidence for the role of reac- tive oxygen metabolites following nonim- munological complement activation.

9. METABOLITES Koh T, Nakai Y’, Kinoshita F, lmura H// l Kyoto Univ, Sch Med, Dept Med, Div 2, Kyoto 606, Japan EUR J PHARMACOL 1988,149 (l-2) 131 Serotonin involvement in the inhibition of luteinizing hormone (LH) release induced by prostaglandin 02 (PGM) in castrated male rats.

Buko VU// Acad Sci BESSR. Inst Biochem. Gmdno. Belorussia, USSR UKR BIOKHIM ZH SSSR 1988,60 (2) 84 Effect of ethanol on prostaglandin metabo- lism in the rat liver (Russian)

Brambalfa Nil Univ Parr Harcourt, Coil Hlth Sci, Drpt Pharmcol, PMB 5323, Port Har- four,, Nigeria EUR J OBSIET GYN REPROD BlOL 1988,27 (4 ) 319 Luteolytic potency of PGD and PGF- Palpha derivatives.

10. RELATED ENZYMES Schmidt KH, Steinhilber D. Moser U. Roth HJ// Univ Tubingen, Dept Surg, D-7100 Tubingen 1, W Germany IN-I- ARCH ALLERGY APPL IMMUNOI. 1988.85 ( 4) 441 L-ascorbic acid modulates 5-lipoxygenase activity in human polymorphonuclear leukocytes.

Davidson, D/i Long Is1 Jewish Hillside Med Ctr. Schneider Childrens Hosp. Div Neonatal Perinatal Med, New Hyde Pk. NY 11042. USA J APPL PHYSIOL 1988,64 (4) 1676 Pulmonary hemodynamics at birth: effect of acute cyclooxygenase inhibition in lambs.

Verbey NIJ, Vanhaeringen NJ, Dejong PTVM N Netherlands Ophthalm Res In!% POB 12141, 1100 AC Amsterdam, Nether- lands CURR EYE RES 1988,7 (4) 361 Modulation of immunogenic keratitis in rabbits by topical administration of in- hibitors of lipoxygenase and cyclooxygenase.

Nagy JT, Foris G, Fulop T. Paragh G. Plot- nikoff NPII Univ Med Sch Debrecen, Dept Med 1, Debrecen, Hungary LIFE SC1 1988,42 (22) 2299 Activation of the lipoxygenase pathway in the methionine enkephalin induced respiratory burst in human polymor- phonuclear leukocytes.

Wagerle LC, Mishra OPN Univ Penn, Sch Med. Dept Physiol, A201 Richards Bldg, Philadelphia, Pa 191oJ, USA CIRC RES 1988,62 (5) 1019 Mechanism of CO2 response in cerebral arteries of the newborn pig: Role of phos- pholipase, cyclooxygenase, and lipoxygenase pathways.

Najid A, Beneytout J-L’, Iablanc J-P. Tiiier M, Rigaud M/i ‘Univ Llmoges. UFR Pharm. Biochim Lab, 2 Rue Docteur Kaymond Marcland, F-87025 Limoges, France BIOCHIM BIOPHYS AlTTA 1988. 960 (1) 26 Evidence for an arachidonic acid 5-, 8- and 15lipoxygenase in Lupinus albus seeds.

11. PRODUCTION AND RELEASE Robblee NM, Famworth ER Bird RP’N *Ludwig Inst Cant Res, Toronto Branch. 9 Earl St. ‘I’oronto, Ontario, Canada M4Y 1M4 LIPIDS 1988,23 (4) 334 Phospholipid profile and production of prostanoids by murine colonic epithelium: Effect of dietary fat.

Boughton-Smith NK, Wallace JL. Morris GP, Whittle BJR// Wellcome Res Labs, Dept Mediator Pharmacol, Beckenham BR3 3BS. England BRIT J PHARMACOL 1988,94 (1) 65 The effect of anti-inflammatory drugs on eiwsanoid formation in a chronic model of inflammatory bowel disease in the rat.

Jaiswal N, Malik KU*// ‘Univ Tennessee, Clr Hlth Sci, Coil Med, 874 Union Ave. Memphis, Tn 38163, USA J PHARMACOL EXP THER 1988, 245 (1) 59

821

Prostaglandin synthesis elicited by cholinergic stimuli is mediated by activa- tion of M2 muscarinic receptors in rabbit heart.

Tsang BK, Arodu J, LI M, Amsworth L, Srrikandakumar A, Downey BR// Ottawa Civic Hosp, Loch Ins.1 Med Res, Dept Obstet 8; Gynecol & Physiol, Ottawa, Ontario, Canada KlY 4E9 BIOL REPROD 1988,38 (3) 627 Gonadotropic regulation of prostaglandin production by ovarian follicular ceils of the pig.

Kirschenbaum MA, Chaudhan Ail Vet Adm Med Ctr, Nephrol Sccl lllN, 5901 E 7th St, Long Beach, Ca 90822, USA EiUR I PlIARMACOL 1988, 148 (3) 335 Lack’ of effect of captopril on preglomerular renal microvascular pros- tanoid biosynthesis.

Pusco B. Salafshy B, Ellenberger B, Li L-H// Univ Illinoa. Coil Med, Dcpt Biomed Sci, 1601 Parkview Ave. Rockford, II 61107, USA J PARASITOL 19888. 74 (2) 253 Schistosoma mansoni: Correlations be- tween mouse strain, skin eicosanoid production, and cercarial skin penetration.

Troyer DA. Gonzalez OF, Douglas JG. Kxls- berg JI// Univ ‘Texas, Hlth %I Ctr, Dept Path@ San Anlonio, TX 782S4, USA BIOCHEM J 1988,251 (3) ‘9f17-912 Phorbol ester inhibits arginine vasopressin activation of phospholipase C and promotes contraction of, and prostaglan- din production by, cultured mesangial CellS

12. EFFECTS Circen IC. l‘adayyon M/i Univ Sussex. Dept Biochem, BrIghton BNl 9QG. E Sussex, England LIFt: SC1 1988.-Q (21) 2123 Opiate-prostaglandin interactions in the regulation of insulin secretion from rat is- lets of Langerhans in vitro.

Ohno K. Sakal T. Fukushima M. Narmmya S’. Fujiwara M/l ‘Kyoto Univ. Fat Med. Dept Pharmacol, Sakyo Ku, Kyoto 606, Japan J PHARMACOL EXP THER 1988, 245 (1) 294 Site and mechanism of growth inhibition by prostaglandins. 4. Effect of cyclopen- tenone prostaglandins on call cycle progression of Gl-enriched HeLa-S3 cells.

Nakamura II, Seto Y. Motoyoshi S, Kadokawa T, Sunahara N// Dainippon Phar- maceut Co Ltd. Rcs Labs. Dept Pharmacol, 33-94 En&l. Suita. Osaka 564, Japan J PHARMACOL EXP TIIER 1988. 245 (1) 336 Recombinant human tumor necrosis fac- tor causes long-lasting and prostaglandin- mediated fever, with little tolerance, in rab- bits

Duda G, Huesken JE. Harmon JW*// *Vet Adm Med Ctr, Dept Surg, Washington. DC 20122, USA 3 SURG RES 1988, u(4) 371 Effects of prostaglandins on esophageal blood flow.

eta S/l

NIPPON SHOKAKIBYO GAKKAI ZAS- SHI lY87 AUG. 84 (8) 1699

The effect of cimetidine on prostaglandin mediated autodefensive mechanism of rat gastric mucosa (Japanese)

Kstsuura G, Gottschall PE. Dahl RR_ Arimura A*// *Tulane Univ. Hebert Ctr, US Japan Biomed Res Labs, Belle Chasse. La 70037. USA ENDOCRINOLOGY 1988,122 (5) 1773 Adrenocorticotropin release induced by in- tracerebroventricular injection of recom- binant human interleukin-1 in rats: Pos- sible involvement of prostaglandin.

Sautereau D, Raze C*l/ ‘Fat Med Xavier Bichat, INSERM, U239. 16 rue I1 Huchard, F 75018 Paris, France GA%IROEN CLIN BIOL 1988. 12 (3) 222 Central effects of prostaglandins on the digestive tract (French)

13. PROSTAGLANDINS IN MEDICINE Egarter C, Husslein P// Vienna Umv. Frauenklin 1, Sp&algassc 23, A 1090 Vienna. Austria ZBL GYNAKOL 1988, I IO (6) 345 Sensitivity test before induction of labour using prostaglandin-E2 vaginal tablets.

14. PROSTAGLANDINS AS DRUGS Reichel F, Scvcikova E, Stumpf J// Rcs lnst Feed Supplements & Vet Drugs. Pohori Chotoun, CS-25449 Jilove. Czechoslovakia BIOL CHEM ZLVOCISNE VYROBY 1988, 24 SI, 4 Oestrop:;;minj SPOFA (cloprostenol) in the animal reproduction (Czech/Slovak)

Kudlac E// Vet Umv Bmo. Dept Farm Amm Reprod & Surg. Palackeho l-3. CS-62142 Bmo, Czechoslovaliia BIOL CHEM ZIVOCISNE VYROBY 1988, 24 SI, 8 The principles of sexual function control in cattle (Czech/Slovak)

Polak L. Jiran E/l Minist Agr & Food CSR. Ctr State Vet, Tesnuv 65, CS-11006 Praha I. Czechoslovakia BIOL CHEM ZIVOCISNE VYROBY 1988, 24 SI. 12 Sexual cycle control in heifers and cows by means of prostaglandin-F2-alpha- analogue under field conditions in the Czech Socialist Republic (Czech/Slovak)

Sevcik B, Mostechy .I, Polak I.. Rychtank V/i Rcs Inst Feed Supplrments & Vet Drugs, Pohori Chouton. C‘S25449 Jlkxe, Clcchos- lovakia BIOL CHEM ZIVOCISNE VYROBY 1988, 24 SI. 15 Oestrophan inj (SPOFA) - Czechoslovak preparation for reproduction control in wholesale commercial (Czech/Slovak)

breeding

Mostechy J. Cap& K, Kubelka V. Palecek J. Stanek J. Stlbor 1. Vesely I// Prague Inst Chem Tcchnol. Suchbatarova 1905. CS-16628 Prague 6, Czechoslovakia BIOL CHEM ZIVOCISNE VYROBY 1988. 24 SI. 19 Synthesis of oestrophan inj (SPOFA) - the preparation for synchronization of estrus in cattle (Czech/Slovak)

Kral J. Dvorak M, Sevcik B, Bilek P, Routa V. Bortelova J// Res Inst Feed Supplements & Ver Drugs, Pohori Chotoun. CS-25449 Jilove. Czech&vakia BIOL CHEM ZIVOCISNE WROBY 1988. 24 SI, 22 Checking on biological activity of oestrophan (SPOFA) in heifers (Czech/Slovak)

Sevcik B, Strakova J, Dvorak M. Svoboda T. Nastuneak J, Rob O// Res Inst Feed Supple- ments & Vet Drugs, Pohori Chotoun, CS- 25449 Jilove. Czechoslovakm BIOL CHEM ZIVOCISNE WROBY 1988. 24 SI. 28 Toxicity and tolerance of oestrophan inj (SPOFA) (Czech/Slovak)

Plchova D, Plcha J. Sevclk B/i Rcs Inst tiecdb Supplements & Vet Drugs, Pohori Chotoun. CS-25449 Jilove, Czechoslovakia BIOL CHEM ZIVOCISNE VYROBY 1988. 24 SI. 36 Endocrine profile after prostaglandin and its analogues administration (Czech/Slovak)

Pichova D, Picha J. Sevcik B. Novotny L.. Mika J. Olsa T// Res Inst Feed Supplements & Vet Drugs, Pohon Chotoun. CS-25449 Jilovc. Czechoslovakia UIOL CHEM ZIVOCISNE VYROBY 1088. 24 SI, 46 Progesterone determination in milk fat and its variation during the sexual cycle and after oestrophan inj (SPOFA) ad- ministration (Czech/Slovak)

Kudlac E. Nedbalkova J. Sludencik Bi; Vet Univ Bmo, Dept Farm Amm Rcprod & surg, Palackeno l-3. CS-61242 Bmo, Czechoslovakia BIOL CHEM ZIVOCISNE WROBY 1988. 24 SI. 51 Synchronization of estrus in heifers by means of the synthetic analogue of PGFP- alpha-oestrophan inj (SPOFA) (Czech/Slovak)

Rwhel F. Caslavka J. Mojzls J. Svab I ,‘/ Rcs lnst Feed Supplements & Vcl Drugs, Pohori Chotoun. CS-25449 Jilove, Czechoslovakm BIOL. CHEM ZIVOCISNl‘ VYROBY 198X. 24 SI, s5 Verification of the preparation oestrophan inj (SPOFA) under the field conditions of estrus synchronization in cattle (Czech/Slovak)

Kudlac E, Vnel M. Vlceh Z. Vmkler A. Vaclavik F/i Vet Umv Bmo. Dept Farm Anim Reprod d Surg, Palacheno l-3. C% 61212 Bmo. Czechoslovakia BIOL CHEM ZIVOCISNE: VYROBY 198x. 24 SI, 58 Therapeutic effect of oestrophan (syn- thetic analogue of prostaglandin-F2-alpha - cloprostenol) in cattle with some fertility disorders (Czech/Slovak)

Relchel F. Sevcik f3, Scvclkova IX, Caslavka J. Svab I, Mojzis J/i Rcs Inst Feed Supplements 6r Vet Drugs, Pohori Chotoun. CS-‘5449 Jllove, Czechoslovakia BIOL CHEM ZIVOCISNE VYROBY 19%. 24 SI. 67 The use of oestrophan inj SPOFA (pros- taglandin-F2-alpha-synthetic analogue - cloprostenol) in therapy of some reproduc- tion disorders in cattle (Czech/Slovak)

B’2

Sevcik B, Km1 J. Strskovs J, Bilek P, Nas- tunesk J// Res Inst Feed Supplements % Vet Drugs, Pohori Chouton, CS-25449 Jilove, Czechoslovakia BIOL CHEM ZIVOCISNE VYROBY 1988, 24 SI, 72 Therapeutic use of oestrophan inj SPOFA (cloprostenol) in cows affected with anestrus and endometritis (Czech/Slovak)

KudIac E, Vlcek z// Vet Univ Bmo. Dept Farm Anim Reprcd dt Surg, Palackeho 1-3, CS-62142 Bmo, Czechoslovakia BIOL CHEM ZIVOCISNE VYROBY 1988, ?4 SI. 76 New methods of ovarian cyst syndrome therapy in cows using the preparation oestrophan inj (SPOFA) (Czech/Slovak)

Jiran E, Polak L, Francirek A, Sailer K // Dist Vet Stn, Bmna Nad Labem, CS~COO3 Usti, Czechoslovakia BIOL CHEM ZIVOCISNE WROBY 1988, 24 SI, 80 Induction and synchronization of parturi- tions in cows (Czech/Slovak)

Kudlac IY/ Vet Univ Bmo, Dept Farm Anim Reprod & Surg, Palackeho 1-3, CS-62142 Bmo, Czechoslovakia BIOL CHEM ZIVOCISNE VYROBY 1988, 24 SI, 84 Endocrinology of a parturition and our ex- perience in its induction in cattle and swines (Czech/Slovak)

Kudlac E. Plachy A, Kmjzl I, Kotman J// Vet Univ Bmo, Dept Farm Anim Reprod & Surg, Palackeho 1-3, CS-62142 Brno, Czechoslovakia BIOL CHEM ZIVOCISNE VYROBY 1988, 24 SI, 88 induction and synchronization of parturi- tions in sows by means of synthetic PGF2- alphaoestrophan (SPOFA) (Czech/Slovak)

the distal esophagus in healthy volunteers (German)

15. INHIBITORS OF SYNTHESIS Tariq M// King Saud Univ, Coil Pharm, Dept Pharmacol, POB 2457, Riyadh 11451, Saudi Arabia RE!.S COMMUN CHEM PATHOL PHARM 1988,60 (1 ) 19 Effect of some new prostaglandin syn- thetase inhibitors on the endotoxin-in- duced mortality and biochemical changes in experimental animals.

Gambino MC, Passaghe S, Chen ZM, Bucchi F, Gori G, Latini R, Degaetano G, Cerletti C’// l Ist Mario Negri. Consotzio Mario Negri Sud, Ctr Ric Biomed & Farmacol, 66OM S Maria Imbaro, Chieti, Italy J PHARMACOL EXP THER 1988, 245 (1) 287 Selectivity of oral aspirin as an inhibitor of platelet vs vascular cyclooxygenase ac- tivity is reduced by portacaval shunt in rats.

Nardone PA, Slotman GJ, Vezeridis MP// Univ Massachusetts, Sch Med, Dept Internal Med, Worcester, Ma 94550, USA J SURG RFS 1988,44 (4) 425 Ketoconazole: a thromboxane synthetaoe and blipoxygenase inhibitor with an- timetastatic activity in BlS-FlO melanoma.

Greven J, Fajam A// Rhein Westfal TH Aachen, Fat Med, Pharmakol Abt, D-SIW Aachen, W Germany PFLUGERS ARCH-EUR J PHYSIOL 1988, 411 (5 ) 579 Effect of inhibitors of prostaglandin syn- thesis on the furosemide action in the loop of Henle of rat kidney.

18. TECHNIQUES O’Brien JR Etherineton MD, Salmon GPII

Podany J, Stejskal J, Jelenek L, Stefan MN St Marys Iiosp, Ceni Lab, Portsmouth PO3

Univ Agr Bmo, Dept Anat, Znmedelska 1, 6Ao England

CS-66265 Bmo, Czechoslovakia THdOMB ms 1988 50 (I) 237

BIOL CHEM ZIVOCISNE VYROBY 1988, DN,9693, a phosphodiesterase inhibitor,

24 SI, 94 compared with prostaglandin El and pros-

Clinical evaluation of oestrophan inj tacyclin in four platelet ‘function’ tests.

(SPOFA) used for synchronization (induc- tion) of parturitions in SOWS (Czech/Slovak)

Hayashi Y er sl,,

TANPAKUSHITSU KAKUSAN KOSO

Kudlac E, Chvatal 0, Elze K// Vet Univ 1987 SEP, (31 Suppl) 90-8 Enzyme immunoassay of prostaglandins

Bmo, Dept Farm Anim Reprod & Surg, (Japanese) Palackeho 1-3, CS-62142 Brno, Czechos- lovakia BIOL CHEM ZIVOCISNE WROBY 1988,

Kohi F, Agrawal DK, Cheng JB, Bewtra A,

24 SI, 98 Townley RG, Olesch JW// Creighton Univ, Sch Med, Ctr Allerg Dis, Omaha, Ne 68178,

The therapeutic use of oestrophan inj USA (SPOFA) in mares with anestrus LIw scI 192k, 42 (22) 2241 (Czech/Slovak) The develooment of a sensitive and

Schwartz KB. Zero B, Burton P. Hunt J, Pen- specific radioreceptor assay for

nellv L. Sevelius H// Syntex Res Corp. Inst leukotriene 84.

Clii Med, 3401 Hillvie& Ave, Palo Alto, Ca 94304, USA ATHEROSCLEROSIS 1988.71 (1) 9 Reduction of serum lipoproteins in man by the oral administration of a prostaglan- din anatcgue (enprostil)

Bsunack AR, Froese G, Demo1 P, Wargenau M. Ruoff HJ, Weihrauch TR// Bayer AG, Pharmaceut Res Ctr, Dept Med, Aprather Weg, D 5600 Wuppertal 1, W Germany Z GASTROENTBROL 19% 26 (4) 199 Effect of rioprostil, an oral prostaglandin- El (PGEI) analogue, on lower esophageal sphincter pressure and on the motility of

Roston DA, Wijayaratne Rc/ Searle Res & Dev, 4901 Searle Pliwy, Skokie, II 60077, USA ANAL CHEM 1988,60 (9) 948 Pdimensional liquid chromatographic method for resolution of prostaglandin enantiomers.

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