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Ultrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case 70 year old male BIB ambulance confused, hypotensive, chest pain BP 70/30, P 120 Undifferentiated Hypotension myocardial infarction GI bleed trauma sepsis tamponade pulmonary embolus pneumothorax dehydration anaphylaxis overdose cardiomyopathy spinal shock Case Undifferentiated Hypotension Hypovolemic Cardiogenic Distributive Obstructive Neurogenic dehydration GI bleed trauma poor oral intake gastroenteritis MI myocarditis toxins/drugs valve insufficiency sepsis anaphylaxis drugs/toxins PE tamponade pneumothorax IPH spinal cord injury brain injury Types of Shock Undifferentiated Hypotension Heart Lungs Volume status Physical Exam Undifferentiated Hypotension Skin color Skin temperature Lung sounds Heart sounds JVD Mucus membranes Vital signs Physical Exam Undifferentiated Hypotension

Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

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Page 1: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

Ultrasound in Shock States

Gavin Budhram, MDBaystate Medical Center

Case

• 70 year old male BIB ambulance

• confused, hypotensive, chest pain

• BP 70/30, P 120

Undifferentiated Hypotension

• myocardial infarction

• GI bleed

• trauma

• sepsis

• tamponade

• pulmonary embolus

• pneumothorax

• dehydration

• anaphylaxis

• overdose

• cardiomyopathy

• spinal shock

CaseUndifferentiated Hypotension

Hypovolemic Cardiogenic Distributive Obstructive Neurogenic

dehydrationGI bleedtraumapoor oral intakegastroenteritis

MImyocarditistoxins/drugsvalve insufficiency

sepsisanaphylaxisdrugs/toxins

PEtamponadepneumothoraxIPH

spinal cord injurybrain injury

Types of ShockUndifferentiated Hypotension

• Heart

• Lungs

• Volume status

Physical ExamUndifferentiated Hypotension

• Skin color

• Skin temperature

• Lung sounds

• Heart sounds

• JVD

• Mucus membranes

• Vital signs

Physical ExamUndifferentiated Hypotension

Page 2: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

• physical exam is subjective

• physical exam unobtainable

• vital signs unreliable

Ultrasound provides direct, objective, and visual evidence of a patient’s circulatory status.

Physical ExamUndifferentiated Hypotension

Clinical AlgorithmUndifferentiated Hypotension

4 Problems can drop pressure

Undifferentiated Hypotension

Clinical Algorithm

Pump Fails

1

Undifferentiated Hypotension

Clinical Algorithm

Congestive Heart Failure

Valve Disease

Myocardial Infarction

Undifferentiated Hypotension

Clinical Algorithm

2

Pipe Leaks

Undifferentiated Hypotension

Clinical Algorithm

Trauma

Ruptured AAA

Ectopic Pregnancy

Page 3: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

Undifferentiated Hypotension

Clinical Algorithm

3

Pipes Enlarge

Undifferentiated Hypotension

Clinical Algorithm

Sepsis

Anaphylaxis

Neurogenic Shock

Undifferentiated Hypotension

Clinical Algorithm

4

Pipes Obstructed

Undifferentiated Hypotension

Clinical Algorithm

Pulmonary Embolus

Pericardial Effusion

Tension Pneumothorax

• 184 patients in shock (SBP<100 or shock index >1), assigned to ultrasound vs no ultrasound

• Ultrasound group: smaller number viable diagnosis at 15 min (4 vs 2)

• Initial diagnosis included final correct diagnosis in 80% (ultrasound) vs 50% (no ultrasound)

Jones et al. Randomized, controlled trial of immediate versus delayed goal-directed ultrasound to identify the cause of non traumatic hypotension in emergency department patients, Crit Care Med 2004

Clinical AlgorithmUndifferentiated Hypotension

• 220 patients in shock randomly assigned to standard care vs. ultrasound to guide management. Followed for 28 days

• Significantly less fluids and more dobutamine used in ultrasound group (49 vs 66ml/kg)

• Improved 28 day survival in US group (66% vs 55%), better urine output, less AKI, more days free of renal support

Kanji et al. Limited echocardiography-guided therapy in subacute shock is associated with change in management and improved outcomes. J Crit Care 2014

Clinical AlgorithmUndifferentiated Hypotension

Page 4: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

IVCdilatedcollapsednormal

Clinical AlgorithmUndifferentiated Hypotension

IVCUndifferentiated Hypotension

IVC Size (cm) Respiratory Changes RA Pressure (cm)

<1.5 Total collapse 0-5

1.5-2.5 >50% collapse 5-10

1.5-2.5 <50% collapse 11-15

>2.5 <50% collapse 16-20

>2.5 No change >20

IVC Estimates of Right Atrial Pressure

IVCUndifferentiated Hypotension

collapsed dilated

•hypovolemic•distributive

•cardiogenic•obstructive

IVCUndifferentiated Hypotension

echopericardial fluidLV functionRV function

dilatedcollapsednormal

IVCdilatedcollapsednormal

Clinical AlgorithmUndifferentiated Hypotension

hyperdynamic hypodynamic

•hypovolemic•obstructive•distributive

•cardiogenic

LV function

EchocardiographyUndifferentiated Hypotension

Page 5: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

EchocardiographyUndifferentiated Hypotension

EchocardiographyUndifferentiated Hypotension

EchocardiographyUndifferentiated Hypotension

EchocardiographyUndifferentiated Hypotension

thoracic scan

echopericardial fluidLV functionRV function

dilatedcollapsednormal

IVCdilatedcollapsednormal

pneumothoraxpulmonary edema

Clinical AlgorithmUndifferentiated Hypotension

Thoracic ScanUndifferentiated Hypotension

Page 6: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

B-lines No B-lines

•cardiogenic •hypovolemic•distributive•obstructive

Thoracic ScanUndifferentiated Hypotension

thoracic scan

echopericardial fluidLV functionRV function

dilatedcollapsednormal

IVCdilatedcollapsednormal

abdominal scanFAST examaortaDVT

Clinical AlgorithmUndifferentiated Hypotension

pneumothoraxpulmonary edema

FASTUndifferentiated Hypotension

AortaUndifferentiated Hypotension

IVC Echo Thoracic

Hypovolemic Collapsed Hyperdynamic No B-lines

Cardiogenic Dilated Hypodynamic B-lines

Distributive Collapsed Hyperdynamic No B-lines

Obstructive Dilated Hyperdynamic No B-lines

Ultrasound AlgorithmUndifferentiated Hypotension

Cases

Page 7: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

Case #1

Chest PainCase #1

58 y/o male colleague c/o chest pain during a shift

Diaphoretic, pale

BP 75/40, P 130

EKG nondiagnostic

Abdomen significantly tender

Chest PainCase #1

Chest PainCase #1

Case #1

Chest PainCase #1

Chest Pain

Page 8: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

Chest PainCase #1

Chest PainCase #1

Fluid/blood resuscitated

CT showed splenic laceration

IR for embolization

History of trauma 3 days ago, forgotten

Abdominal Pain

IVC Echo Thoracic

Hypovolemic Collapsed Hyperdynamic No B-lines

Cardiogenic Dilated Hypodynamic B-lines

Distributive Collapsed Hyperdynamic No B-lines

Obstructive Dilated Hyperdynamic No B-lines

Case #1

Case #2

AMS, Hypothermia

• 45 y/o female found down in her home

• confused, lethargic

• T91, BP 70/30, P140, O2 100%, RR 35

Case #2

• IV access established, fluids bolused

• EKG

• Blood drawn

• Warming started

AMS, HypothermiaCase #2

Page 9: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

AMS, HypothermiaCase #2

AMS, HypothermiaCase #2

AMS, HypothermiaCase #2

AMS, HypothermiaCase #2

• FSBS critical high

• Lab glucose 1200, CO2 6

• Fluids, insulin gtt, antibiotics, admitted MICU

AMS, HypothermiaCase #2

IVC Echo Thoracic

Hypovolemic Collapsed Hyperdynamic No B-lines

Cardiogenic Dilated Hypodynamic B-lines

Distributive Collapsed Hyperdynamic No B-lines

Obstructive Dilated Hyperdynamic No B-lines

AMS, HypothermiaCase #2

Page 10: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

Case #3

Weakness, Hypoxia

• 22 y/o male, no PMHx, c/o severe weakness, DOE.

• Has been huffing “Dust-Off” for the last 3 months, 6 cans daily

Case #3

• Vitals: pulse 90, BP 90/70, O2 85% RA, afebrile

• Lungs: occasional crackles, appears mildly dyspneic

• CV: RRR

Weakness, HypoxiaCase #3

Weakness, HypoxiaCase #3

Weakness, HypoxiaCase #3

Weakness, HypoxiaCase #3

Page 11: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

Weakness, HypoxiaCase #3

• Toxic myocarditis—hydrocarbons

• EF 6%

• Eventually improved over months

Weakness, HypoxiaCase #3

Weakness, Hypoxia

IVC Echo Thoracic

Hypovolemic Collapsed Hyperdynamic No B-lines

Cardiogenic Dilated Hypodynamic B-lines

Distributive Collapsed Hyperdynamic No B-lines

Obstructive Dilated Hyperdynamic No B-lines

Case #3

Case #4

74 y/o male, recent hip fracture, weakness and hypotension

62/34, P 86, 99% 4LNC, RR20

WeakCase #4

Patient arrested shortly after arrival to the emergency department

WeakCase #4

Page 12: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

WeakCase #4

Empiric thrombolytics initiatedIV fluids, norepinephrine,

BP, pulse stabilized. Admitted to intensive care unit

WeakCase #4

IVC Echo Thoracic

Hypovolemic Collapsed Hyperdynamic No B-lines

Cardiogenic Dilated Hypodynamic B-lines

Distributive Collapsed Hyperdynamic No B-lines

Obstructive Dilated Hyperdynamic No B-lines

WeakCase #4

Case #5

43 y/o female with metastatic breast CA (lungs, ribs), DVT on enoxaparin

3 days of worsening lethargy, vomiting, dehydrationT 97.9, P 139, BP 96/68, O2 95%

Presumed pneumonia

Pt received 2LNS, P 140, BP 95/70

Page 13: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

Moderate-large pericardial effusion

P150, BP 70/30

700cc bloody fluid aspiratedVitals normalized post procedure

IVC Echo Thoracic

Hypovolemic Collapsed Hyperdynamic No B-lines

Cardiogenic Dilated Hypodynamic B-lines

Distributive Collapsed Hyperdynamic No B-lines

Obstructive Dilated Hyperdynamic No B-lines

Case #6

Chest Pain, Hypotension

• 72 y/o male sent from NH for CP, hypotension.

• Previous MI with stenting

Case #6

• BP: 70/30, P 105, RR 24, O2 89%, T 95

• Awake but confused, tachycardic, decreased breath sounds, skin warm & dry

• EKG nondiagnostic

Chest Pain, HypotensionCase #6

Chest Pain, HypotensionCase #6

Page 14: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

Chest Pain, HypotensionCase #6

Chest Pain, HypotensionCase #6

Chest Pain, HypotensionCase #6

Chest Pain, HypotensionCase #6

• Fluids bolused, central access, broad antibiotics

• Troponin negative, WBC 24

• admitted to MICU

Chest Pain, HypotensionCase #6

Case #7

Page 15: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

• 72 y/o male with hypotension, acute chest discomfort

• P 160, BP 80/40, O2 95% RA

CP, hypotensionCase #7

CP, hypotensionCase #7

CP, hypotensionCase #7

CP, hypotensionCase #7

CP, hypotensionCase #7

CP, hypotensionCase #7

Page 16: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

Dyspnea, Hypotension, CPCase #7

IVC Echo Thoracic

Hypovolemic Collapsed Hyperdynamic No B-lines

Cardiogenic Dilated Hypodynamic B-lines

Distributive Collapsed Hyperdynamic No B-lines

Obstructive Dilated Hyperdynamic No B-lines

Case #8

HypotensionCase #8

• 72 y/o male with hypotension, sent from NH

• P 160, BP 80/40, O2 95% RA

HypotensionCase #8

HypotensionCase #8

HypotensionCase #8

Page 17: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

HypotensionCase #8

HypotensionCase #8

• Fluids started, BP improved, converted spontaneously

• WBC 30, UA with copious bacteria

HypotensionCase #8

Case #9

Cough, Fever, Hypoxia

• 89 y/o female, h/o CHF, presented with 1 week subjective fevers, worsening SOB, productive cough.

• No CP, chronic baseline leg swelling

Case #9

• Vitals: P92, BP 130/58, O2 81%, T98.2.

• Appears dyspneic, speaking in short phrases, lungs with wheezes, crackles. RRR. Trace symmetric pedal edema.

• Initial presumption pneumonia

Cough, Fever, HypoxiaCase #9

Page 18: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

Cough, Fever, HypoxiaCase #9

• Started on antibiotics, admission arranged.

• Sign out: pt becoming hypotensive, bp 80/50. Unsure if fluids/no fluids.

• Pneumonia vs pulmonary edema

Cough, Fever, HypoxiaCase #9

Cough, Fever, HypoxiaCase #9

Cough, Fever, HypoxiaCase #9

Cough, Fever, HypoxiaCase #9

• Placed on bipap, inotropes

• Pressure improved, bed changed to CCU service.

Cough, Fever, HypoxiaCase #9

Page 19: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

IVC Echo Thoracic

Hypovolemic Collapsed Hyperdynamic No B-lines

Cardiogenic Dilated Hypodynamic B-lines

Distributive Collapsed Hyperdynamic No B-lines

Obstructive Dilated Hyperdynamic No B-lines

Cough, Fever, HypoxiaCase #9

Case #10

Weakness, Hypotension

• 83 y/o female, increasing weakness, dizziness x1 week

• PMHx: multiple previous MI’s

• Vitals: P 90, BP 75/30, RR 25, T 98, O2 92%RA

Case #10

Weakness, HypotensionCase #10

Weakness, HypotensionCase #10

Weakness, HypotensionCase #10

Page 20: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

Dyspnea on Exertion, Hypoxia

• More NH information: large amount of diarrhea

• Guaiac positive

• Hypovolemic with pre-existing LV systolic dysfunction

Case #10

Case #11

Near Syncope

• 67 yo male with dizziness, near syncope, acute L. testicular pain 1 hour PTA while playing cards

• BP 80/30 P115 O2 95% T98

• Abd soft, L. scrotum purple and tender

Case #11

Near SyncopeCase #11

Near SyncopeCase #11

Near SyncopeCase #11

Page 21: Ultrasound in Shock States - Undifferentiated Hypotension.pdfUltrasound in Shock States Gavin Budhram, MD Baystate Medical Center Case • 70 year old male BIB ambulance • confused,

Near Syncope

• Vascular surgery paged, pt to OR

• Large ruptured retroperitoneal aneurysm

• Arrested in surgery

Case #11

Case #12

82 y/o male with known CAD, with 3 hours severe CP and SOB

P130, R 35, BP 90/40, O2 78%Dyspneic, bilateral crackles, tachy/regular

Labs: Hgb 4.9, Hct 15.9Guaiac +

High-output failureEventually needed 6U PRBCs, cauterized bleeding gastric

ulcer

Summary

• Organized approach to critical patients

• Evolving field for ultrasound

• Requires a new way of thinking

Final Thoughts