UnivErSiTy LabS · The definitive source for lab products, news and developments Canadian Publications Mail Product Sales Agreement 40063567 Labs Go Green Second-hand Equipment David

Spring 2010 www.labbusinessmag.com

The definitive source for lab products, news and developments

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UnivErSiTy LabSLearn Lessons in the New 3 Rs Reduce, Re-use, Recycle

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Lab business Spring 2010 3

12 Celebrating 25 yearsSince our humble beginnings 25 years ago, we’ve been there through all of the industry’s advances and achievements.

20 Lab SpotlightSaskatoon’s VIDO-InterVac is getting a $140- million facelift: a new CL3 facility that represents the largest vaccine research investment ever in Canada.

25 Suzuki CommentDavid Suzuki says you can’t have healthy people without a healthy environment.

29 Tech WatchAutomation

34 Sitting WithMeet Christine Nielsen, new Executive Director of the Canadian Society for Medical Laboratory Science (CSMLS).

SPrinG 2010 www.labbusinessmag.com


also inside

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On THE COvEr: architects from HOK, took Carleton University’s Steacie Superlab from a dated, wasteful space to a modern, efficient teaching lab.

Photo Credit: HOK

COvEr STOry it is estimated that laboratories use anywhere from five to 10 times more energy than the average office building. Some labs across Canada, and in particular, university labs, and the people who build them, are already working hard to reduce over-con-sumption of energy. “Sustainability,” from the early stages of construction right through to everyday use, is becoming a central theme in the industry.

Spring 2010 www.labbusinessmag.com


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UnivErSiTy LabSLearn Lessons in the New 3 Rs Reduce, Re-use, Recycle

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How do you keep your business afloat in unchartered waters?

Follow your (perhaps, ill-fated) competitor

Take advice from a neighbour/psychic/mother in-law

Visit the

Access over 1,000 biosphere studies from world-leading publishers such as....

However, this requires a source of guidance or intelligence.The LAB Business Research store provides affordable access to a wealth of detailed and commerically-focussed studies published by world-leading publishers who offer the first and last word in healthcare industry insight.

You need to make informed decisons in business.

VISIT

march_2010-matt.indd 1 19/03/2010 10:51:54


Serving Canadian Laboratories and Lab Suppliers

since 1985

Publisher Christopher J. Forbes & CEO [email protected]

Executive Theresa Rogers Editor [email protected]

Editor Bernadette Johnson [email protected]

Staff Writer Jason Hagerman

Contributors James A. Kaufman David Suzuki

Art Tammy White Director [email protected]

Secretary/ Susan A. Browne Treasurer [email protected]

Sales Beth Kukkonen Manager [email protected]

National Janet Jeffery Account Executive [email protected]

Account Michael Valentino Co-ordinator [email protected]

Communications Nicole Burnie Associate [email protected]

Production Roberta Dick Manager [email protected]

Production Joanna Forbes Co-ordinator [email protected]

Lab Business is published 4 times per year by Jesmar Communications Inc., 30 East Beaver Creek Rd., Suite 202, Richmond Hill, Ontario L4B 1J2. 905.886.5040 Fax: 905.886.6615 www.labbusinessmag.com One year subscription: Canada $35.00, US $35.00 and foreign $95. Single copies $9.00. Please add GST where applicable. Lab Business Subscription and circulation enquiries: Garth Atkinson, [email protected] Fax: 905.509.0735 Subscriptions to business address only. On occasion, our list is made available to organizations whose products or services may be of interest to you. If you’d rather not receive information, write to us at the address above or call 905.509.3511 The contents of this publication may not be reproduced either in part or in whole without the written consent of the publisher. GST Registration #R124380270.

PUBLICATIONS MAIL AGREEMENT NO. 40063567RETURN UNDELIVERABLE CANADIAN ADDRESSES TOCIRCULATION DEPT.202-30 EAST BEAVER CREEK RDRICHMOND HILL, ON L4B 1J2email: [email protected]

Jesmar CommuniCations inC. Publisher of

Lab business MagazineLab business Cards

bio business Magazine

Printed in Canada

hen you factor in editorial deadlines and the fact i knew what i wanted to say—to tell you about our plans for 2010—i had this column written months ago.

none of that matters as much now. Life has thrown us a curveball.as you may know, my dear friend and fellow editor, bernadette Johnson, has been

absent from these pages since she had a baby early last year. in addition, her husband, Tom, diagnosed with a brain tumour in 2007, learned about six months ago that a new tumour had begun growing. Determined in their fight, it inspired us to do everything we could to help. We have held bake sales and auctions, and this year, we’ll be partnering with the brain Tumour Foundation of Canada in a big way: portions of ad sales will be donated to the foundation. We hope these research dollars will help everyone affected by a brain tumour in their fight. Charity has always been a large part of the Jesmar culture, but never has it hit so close to home.

now, Tom has passed away after a courageous fight with that second tumour.Tom, it was a privilege to have known you and witnessed the joy you brought to

bernadette. it is a privilege to know that because of you, others with brain tumours will also have a fighting chance. it is a privilege for me to write this column where i can talk to people whose research, no matter what the field, makes a difference and touches lives on a daily basis.

events like this really do make you think about what truly matters in life—the love, health and happiness we experience with each other. To all who have touched my life, thank you.

Theresa [email protected]

in Loving Memory

W

editor’s note

new to our website this year—a research store and news feed! our research store provides access to a wealth of relevant, timely and robust intelligence

from world-leading sources. More than 1,500 recent reports are available, tailored specifically to biotech, pharma and healthcare industries—enabling you to make better strategic and operational decisions and continue to be commercially agile. Go to www.labbusinessmag.com/researchstore to browse all of the reports, or click on the various tabs to explore company profiles and the latest industry news.

6 Spring 2010 Lab business

I started Jesmar Communications 25 years ago. i have to sit and let that number sink in. Twenty-five years.

sometimes it seems like just days have passed, and sometimes it seems like eons. it must be the latter, because the world is a very different place than it was when i sat deciding on the banner that the company would fly under. Those days, the radio would be singing the tune of ‘We are the World’ or the ‘Theme song from Miami Vice’. Watercooler talk would have centred around movies like Back to the Future and Rocky IV and how Michael J. Fox won best actor for Family Ties. a new house would have cost $100,000 and i could have filled up my gas tank at 43 cents/litre. Yes, a lot certainly has changed.

We started out doing Lab Business Cards. These “bingo” reply cards were sent to our circulation and required putting a stamp on the card, handwriting in the information and mailing the cards back. in 1989, we evolved to Lab Business Literature Review, a booklet of “lit reviews” running 12 pages long. as we delved into editorial content, this quickly this grew into something more complete. This was the first real incarnation of LAB

Business magazine. advertising started coming in thanks to some great folks like aaron Wolkoff, ed Godman and bruce smith, professionals who were willing to take a chance on a fledgling publication, and whose kindness will never be forgot-ten. Bio Business was added to speak to the life sciences industry in 1998 with top-notch editors joining our team.

as we move forward, we are commit-ted to sending you the most up-to-date and meaningful Lab and bio news and applications. in both print and now online, we are happy to continue serving the most important and vital industries in Canada.

Publisher & Ceo Chris Forbes

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publisher’s note


Green Report news beat

Trent university’s Dr. suresh narine, an internationally

renowned expert in the field of biomaterials, has been awarded one of two $1.25 million ontario Research Chairs in Green Chemistry and engineering by the ontario Research Chairs selection Panel.

The award celebrates the scien-tific expertise emerging at Trent university with the recent launch of both the Trent biomaterials Research Program and the Centre of Knowledge in the environment. as ontario Research Chair, narine will receive funding of $250,000 a year for five years.

“i am deeply honoured by this selection,” says narine, who came to Trent from the university of alberta in september, 2009. “This chair not only represents a highly opportune and important addition to the university’s research and development strengths in the areas of chemistry, environmental and resource science/studies, physics and materials science, but it will also assist in creating new path-ways for Trent students to learn about and gain important experi-ence in the emerging field of green chemistry.”www.trentu.ca

Spotlight on Reproductive Health

Two teams from the Research institute of the McGill university Health Centre (Ri-MuHC) and McGill university recently received significant support from the

Canadian institutes of Health Research (CiHR) amounting to $5 million over five years.The CiHR team led by Dr. Cindy Goodyer, Director of the endocrine Research

Laboratory at the Ri-MuHC-Montreal Children’s Hospital, and Dr. barbara Hales, Professor of Pharmacology and Therapeutics at McGill, received $2.5 million to study the effects of brominated flame retardants on reproductive health.

“This is a serious issue,” says Goodyer. “not only is an individual’s health potentially at risk, but also that of future generations.”

The CiHR team led by Dr. bernard Robaire, researcher in the Human Reproduction and Development axis of the Ri-MuHC, has received $2.5 million. They will study the mechanisms underlying the male reproductive toxicity of phthalates, a family of com-pounds found in plastics.

“The challenge is to replace phthalates in plastics by ‘green’ plasticizers, which should not be toxic and, ideally, should be biodegradable to avoid any accumulation in the envi-ronment. More research is essential to understand the possible impact of these com-pounds on the endocrine system and, more specifically, how they may adversely affect male reproduction,” explains Robaire.www.cihr.ca

Ancient Signs of Life Found in Rock

A University of Manitoba researcher is one of an international team of geologists who have announced the discovery of what may be evidence of

the oldest complex life form on Earth. They found fossilized microorganisms that were deposited in ancient marine sediment about 3.2 billion years ago.

“These are the oldest large microfossils with significant implications for the evolution of life,” says Andrey Bekker, geological sciences.

Bekker, along with colleagues Emmanuelle Javaux of the University of Liege and Craig Marshall of the University of Kansas, published their findings in a recent issue of the journal Nature.

The researchers examined shale samples from drill cores 600 metres below the surface in South Africa. They found unmistakeable fossilized microorganisms that had been well-preserved. This effectively pushes back the earliest evidence of complex life that lived on Earth to at least 3.2 billion years, which means that life on Earth began to form within less than one and a half billion years after planetary formation.

Previously, the oldest reliable evidence of advanced life found were fossilized bacteria in rock less than two billion years old.www.umanitoba.ca

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news beat

trailing in Innovation

Canada continues to be a “D” performer on innovation in the Conference board of

Canada’s latest How Canada Performs report card, ranking 14th among 17 peer countries.

“Canada is well-supplied with educational institutions and carries out scientific research that is well-respected around the world,” says Gilles Rheaume, Vice-President, Public Policy. “but, with a few exceptions, Canada does not successfully commercialize its scientific and technological discoveries into world-leading products and services. Canadian companies are rarely at the leading edge of new technology and find themselves a step behind the leaders.”

Countries with the highest overall scores have developed successful national strategies for innovation, giving them global leadership in one or more areas. For example:

• Switzerland, the top-ranked country, is a leader in the pharmaceuticals industry. • Ireland is the host of innovative information technology companies, and is a leader

in high and medium-high technology manufacturing. • The United States fosters a combination of top science and engineering facilities,

broad and deep capital markets, and an entrepreneurial culture. it is a leader in share of world patents and knowledge-intensive services.

Canadian firms were considered to be early leaders in biotechnology, but Canada has since fallen behind in the field. This is attributed to complex and time-consuming regulatory processes, slow technology adoption rates and increasing tendencies for Canadian companies to ignore domestic markets for their new products. The study finds that firms currently face longer regulatory approval times in Canada than competitors in other countries. www.conferenceboard.ca

Powering the FutureUniversite de Sherbrooke physicist Louis Taillefer and a group of

scientists studying superconductor technology recently made a breakthrough in high temperature superconductivity.

While superconductors work best at the lowest theoretically possible temperature: - 273.15 C, Taillefer’s work focused on an

easier to achieve -100 C.The findings reveal an underlying force not previously understood, Taillefer

says. They also reduce theories explaining high-temperature superconductivity from dozens to only a few.

The ultimate goal is to create a superconductor that can function at room temperature.

“Now we’re pretty sure we know how to get there,” Taillefer says.Achieving that would mean MRIs could be much smaller, even portable, since

they would not need large and hugely expensive cooling systems. Five times more electricity could be transmitted in the space now required for standard transmis-sion lines.

The research involved years of painstaking observation of crystals of yttrium barium copper oxide super cooled in a special refrigerator. The cleanliness of the crystals produced by the team at UBC went a long way to providing the best results, Taillefer added.www.usherbrooke.cawww.ubc.ca

Fire and Waters

Aaron Wolkoff, President of Waters, carried the olympic torch 300 metres

through the town of acton, ontario early on the morning of December 21, 2009.

“one of the most interesting things about it was that in all the world, i was the only person carrying the flame at that time. it was awesome,” Wolkoff says.

Picking up the flame at around 8 a.m., with the sun slowly rising above the hori-zon, he held it aloft for no more than five minutes, but calls the run an important accomplishment.

“i had some very serious surgery a few years ago and i just felt that it was sort of an accomplishment,” he says. “i had it for less than five minutes, but it served as a point that i could tell myself, ‘i have made it and i’ve recovered from my surgery.’”

in front of 45 friends, family and coworkers (and hundreds of other onlook-ers), Wolkoff carried the flame through the crowd, relishing in the spectacle with those around him.

“The biggest thrill was from all the kids around wanting to touch the torch,” he says.

The torch now rests on the mantle in his home and cleaning fingerprints from the glimmering hilt is a regular activity.

“To me, this was an incredible experi-ence, a personal achievement and hum-bling as well,” he says.


AppointmentsCSMLS Executive DirectorChristine Nielsen has been hired as Executive Director of the Canadian Society for Medical Laboratory Science (CSMLS).

Nielsen is well known and respected within the medical labora-tory community. She was the Director of Certification for the CSMLS from 2003 to September of 2009. Most recently, she was Associate Registrar and Member Relations Team Leader at the College of Medical Laboratory Technologists of Ontario (CMLTO). Prior to joining CSMLS in 2003, she worked at the Michener Institute for Applied Health Sciences.

Fresh Marketing PerspectiveDiteba Research Laboratories Inc. announced the appointment of Sam Ricchezza to the position of Senior Vice-President of Business Development. Ricchezza will be responsible for Diteba’s business development and marketing efforts.

Ricchezza has more than 14 years of business development and marketing experience in the pharma-ceutical contract development and manufacturing industry, having held a number of progressively responsi-ble business development positions over the course of his career.

Professor stephen Hawking will visit the Perimeter institute for Theoretical

Physics (Pi) in Waterloo, ontario, this summer to conduct scientific research and participate in a televised outreach event.

The world’s most famous living physi-cist, Hawking has made several monu-mental contributions to theoretical phys-ics. His visit to Waterloo in June and July of 2010 will focus primarily on scientific research and private collaborations with

Science in Sudbury

The ontario government is supporting researchers in sudbury exploring topics ranging from the nature of the

universe to improved treatments for alcohol addiction.in total, the province is supporting 120 researchers at

Laurentian university and the sudbury neutrino observatory (snoLab) including:• Dr. Randy W. Dirszowsky, who is discovering new ways to assess and reduce soil erosion

in northern ontario, an important step to improving land, air and water quality.• Dr. Annie Roy-Charland, developing a better understanding of how brain disorders

such as alcohol addiction affect learning patterns and skills development.• Dr. Jeffrey L. Shephard, who is developing the next generation of cost-effective, nano-

sized devices that can perform a range of chemical and biological processes needed in medical and environmental industries.

• Dr. Mark Boulay and Dr. Mark Chen, whose research is related to dark matter, will use state-of-the-art technology 2,000 metres below ground to advance our understanding of how dark matter affects the universe.

www.snolab.cawww.laurentian.ca

giving BackA University of British Columbia (UBC) alumnus widely

credited for mentoring Google’s founders and helping establish the company is supporting science education trans-

formations with a $2 million gift to the Carl Wieman Science Education Initiative (CWSEI).

The gift will support the transformation of core, required courses in the Faculty of Science departments of computer science and mathematics over the next five years with the help of the CWSEI, positively impacting thousands of students a year.

“Investment in the next generation is the best and most important one I can make, and education has to top the list,” Cheriton says.www.cwsei.ubc.ca

other leading physicists at Pi. Hawking will also take part in the institute’s award-winning outreach program by delivering a special lecture to be broadcast on TVo across Canada.

“We hope stephen’s visit to Perimeter will be just the first of many,” Pi Director neil Turok says. “His ideas have had a huge impact on our basic understanding of the universe. He is an exceptional com-municator, whether to other scientists or

to the wider public. We are delighted he has agreed to deliver a televised lecture, to be shown across Canada. and we are looking for-ward to his impressions of the ‘stephen Hawking Centre at Perimeter institute’ now under construction.”www.perimeterinstitute.ca

Hawking to Visit Waterloo


Dr. James A. Kaufman is the founder and president of The Laboratory Safety Institute (LSI) www.labsafetyinstitute.org—an interna-tional, non-profit centre for safety in science and science education. LSI provides workshops, seminars, on-site training programs, lab safety program development consultations, facilities inspections and regulatory compliance assistance. Contact LSI with all your lab safety questions: (508) 647-1900 or [email protected].

The list is incomplete. Let’s add bleed-ing, burns, medical situations, electric

shock, and weather emergencies.one of my biggest surprises was dis-

covering about 15 years ago that teachers do not have written emergency plans and that they don’t discuss these issues in their science departments. When ques-tioned about these two points, only about five per cent of science teachers say yes. What about your company? Most are not much better!

The only good way to prepare for an emergency situation is to think through how you should respond and then practice doing it correctly. Regular drills and exercises are essential. in most cases, the first decision involves deciding whether to evacuate or not. no one will ever fault you for saving people and losing the facilities.

if you are starting from scratch in your department, have an emergency of the month. assign one of the above emer-gencies to a pair of teachers/employees and ask them to draft a model response to be discussed at the next department meeting. The following month, pick a new emergency and a new teacher/employee pair. in small departments/companies, invite other departments and maintenance people to join you.

one last word of advice... PRaCTiCe. You can’t get good at anything without practice. Dealing with emergencies is no

By Dr. James A. Kaufman

safety zone

Emergency Planning Develop plans and conduct drills for dealing with emergencies such as fire, explosion, poisoning, chemical spill or vapour release, and personal contamination

exception. each month, ask the folks in one of your labs to decide what would be the worst thing that could happen in their lab. Let them stage a mock event and have everyone else respond (hope-fully) appropriately. afterwards, sit down together and ask two simple questions:

1) How did we do?2) How can we do it better?

Post the phone numbers of local fire, police and ambulance departments by every phone

in an emer-gency, you tend to forget even the most common things. Having emergency phone numbers and direc-tions by every phone is a very important reminder. substitute teachers and others new to your facilities need this reminder even more. Don’t obstruct this vital information with other posted notices around the phone.

Providing extra phone number stick-ers to your employees, faculty, staff, and students is another good way to extend that safety program beyond the work-place/classroom.

What should you do if you have no

phone? better be planning ahead as dis-cussed above. one relatively inexpensive solution might be a pair of wireless inter-coms (Radio shack $50-100). another good practice is to train a pair of students or employees as emergency responders. They know where to go and who to speak to in an emergency to help ensure that they get immediate assistance and that their message is taken seriously. LB


change their models and concepts,” he says.it has taken a long time to translate the full benefits of this

change into advances in microscopy on the bench level, england says, but the things happening today are all made possible by making the move to lengthen the infinity space.

“The biggest impact has been in digital imaging, computeriza-tion and automation. You can look at something now like the nikon Perfect Focus system, which will allow users to run long-term experimentation and maintain focus through the entire timeframe,” he says.

Prior to this kind of focal stability, it would have been common for a long-term image to lose focus halfway through the experi-ment.

“You could run experiments for days and then find out that you had an issue overnight: a thermal drift or some vibration. The advances with infinity space allowed that perfect focus system to fit within the microscope optics and hold focus over time,” says england.

This dramatically increased efficiency. Looking at the differences between 2010 and 1985, ergonom-

ics have become more important as well. benchtop optical sys-tems tout well-positioned eyepieces and adjustment knobs. Resolution has also changed drastically, and scientists are able to examine materials and objects with incredible precision.

“now, it’s getting down to trying to find ways around the laws of physics,” says england.

The year was 1985, and after almost 10 years selling advertising for southam, inc., Chris

Forbes was ready for a change. He struck out on his own, into the wilderness of Canadian entrepreneurship, selling mail-based advertisements. With a mailing list of 25,000, Forbes became his own boss at the helm of Jesmar Communications, inc.

“soon, cards were no longer enough, so i decided to do a magazine,” says Forbes. in the early months of the 1990s, Laboratory Business Literature Directory was released, and the first company to take a chance on the fledgling 12-page directory was life sciences product developer and manufacturer, Waters. Much has changed since then. LAB Business magazine and Bio Business magazine now each boast 40 pages of Canadian industry news and information and reach a combined audience of almost 73,500 with each issue.

During Jesmar’s maturing, Canada has seen eight federal elec-tions, five Prime Ministers and a bottle of ardbeg, Lord of the isles single-malt whiskey will have aged nicely. in 25 years, a lot can happen. in the world of science and technology, this is doubly true. The cellular telephone today, for example, is a fraction of the size and price that it was in 1985, and has exponentially more functionality and power. Do you remember what qualified as state-of-the-art in the lab 25 years ago?

according to Wayne england, General Manager, instruments Division at nikon, 25 years ago, microscopes had reached the limit of their abilities.

“but something happened, and the industry went through a major redesign in optics,” says england. infinity space in the way that we now know it was, essentially, perfected.

“When that happened, everybody in the industry had to

BeginningsHumble

LAB Business publisher, Jesmar Communications, celebrates its 25th anniversary with a look back

The very idea of the Nikon A1-Ti would have been dismissed as

science fiction even 25 years ago.

By Jason Hagerman

Celebrating 25 years


Chromatographyin 1985, Dorothy Phillips worked her first day as an employee at Waters. “i came here to develop chromatography packing materials for bioseparations, in this new area of biotechnology,” she says.

The major difference in chromatography between that first day, 25 years ago, and today; the particle size researchers are able to utilize.

state-of-the-art particle size for something like ion exchange, Phillips explains, would have measured around eight microns. additionally, researchers were doomed to spend hours upon hours working in a cold room in order to maintain protein integrity.

“a typical chromatogram could take an hour-and-a-half or two hours with peaks that were two or three minutes wide in some cases,” she says.

Today, instead of having peaks that are two or three minutes wide, an entire chromatogram will be two or three minutes long.

“in that, you can separate five or six proteins,” says Phillips. in addition, scientists are also able to work in the comfort of a

normal lab setting, as samples can be chilled in the autosampler. Chromatography systems operated at lower pressures (around

1,000 psi) 25 years ago, and utilized glass columns. Today, steel columns are used, implanted with a silica-based rigid material that can take higher pressure than previously utilized soft gels. Waters offers a chromatography system now that has a maximum pres-sure of 15,000 psi.

“in the future, many of the modes of chromatography will be driven down to smaller particle sizes,” says Phillips.

Research funding“as i remember it, back in the mid-80s was a bit of a low point in funding, at least for me. it was not easy to come by money, funds were tight and research grants were rather small,” says Dr. Ray March, professor emeritus of Chemistry at Trent university. “The way i remember it, there were just many demands for money.”

one method to secure funding was to partner with industry, and that was what March did.

“i worked with an american company which had a Canadian office, which really had nothing to do with the work we were doing. nevertheless, we got money through our activities with them. We had to do this in order to stay active,” he says.

When the Canadian Foundation for innovation (CFi) started in the mid-90s, March saw a decided shift in funding.

now, March heads up a lab with 17 mass spec systems, which he is able to maintain through grants from CFi, the natural sciences and engineering Research Council of Canada (nseRC), and a few other funding sources.

in his time, March says, collaboration has blossomed thanks to the internet, where collaborating with colleagues across the atlantic ocean used to be a constant struggle.

www.biobusinessmag.com

Championing the Business of BioteChnology in Canada November 2009

Innovation and entrepreneurship in the Canadian biotech landscape

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Genesis Genomics turns cancer research on its head, finding the keys to the cancer puzzle in mtDNA

Q&ANRC President Pierre Coulombe

Biofuels Value Chain elements to achieve maximum return

Cancer ConundrumCancer Conundrum

5

BB_NovDec09_Issue.indd 1 11/25/09 2:19 PM

LB


lab spotlight

ccording to the united states environmental Protection agency, laboratories use anywhere from five to 10 times more energy than the average office building. some labs across Canada, and in particular, university labs, and the

people who build them, are already working hard to reduce over-consumption of energy. “sustainability,” from the early stages of construction right through to everyday use, is becoming a central theme in the industry.

putting “green” to useLooking down from the surrounding buildings, it may look like a grouping of small fields has been left to grow in the centre of McGill university’s densely developed campus. in fact, you’d be looking down on the several-stories high roof of the McGill Life sciences Complex, one of the Canadian lab facilities that have taken to heart, the necessity of sustainability.

Here, green is more than trendy word. The grass-covered “green roof ” is a functional, and very visible, design element hint-ing of the energy-saving systems operating silently throughout the lab.

“The green roof serves a number of purposes,” says Robb Graham of Diamond and schmitt architects inc., the firm responsible for designing the complex.

according to Graham, the roof reduces heat gain that would

THE THrEE rS

By Jason Hagerman

Forget reading, ’riting and

’rithmatic. the new buzz at

Canadian universities at the

forefront of sustainable lab

construction and design is

reduce, re-use and recycle

A

Students make use of the newly invigourated, bright and open Steacie Superlab at Carleton University. As many as 120 students can use the lab at a given time.


Green Report

be garnered from a traditional tar or black-shingle covering. This means less energy will be spent keeping the internal air tempera-ture comfortable for the few thousand scientists, students, staff and visitors who enter the building daily.

if the green roof were not in place, Graham says, simply employing a lighter coloured surface could also reduce heat gain. However, in order to obtain its Leadership in energy and environmental Design (LeeD) Green building Gold rating, the roof at McGill was implemented to perform multiple functions.

“[The Life sciences Complex] has an extensive water conser-vation system,” says Graham. “it’s got a 50,000 litre cistern that recovers water from the green roof and feeds it to the toilets and

urinals throughout the building, so it’s using grey water as opposed to fresh water from the city system.”

Taking into consideration that Canada is one of the most poorly ranked countries when it comes to water consumption (according to the organisation for economic Co-operation and Development), this is an important part of the sustainable design of the complex.

Green roof systems have been around for a number of years and have advanced in design and functionality. implementing a system such as this comes at a premium, Graham says, but it will quickly return value.

“They are expensive to begin with, but in the long run a system like this pays for itself. We’re trying to target payback on the capital expenditure in three to five years,” he explains.

Many possibilitiesThe “green roof ” that McGill’s complex utilizes isn’t the sole option for rooftop energy systems. The CanMeT MTL build-


lab spotlight

ing, funded by natural Resources Canada and under construction in Hamilton’s McMaster innovation Park, will use the roof to harness the abundant energy of the sun.

“The massive plane that forms one partial roof and partial side of the mechanical penthouse is actually a solar wall,” says birgit siber, an expert in green design with Diamond and schmitt.

This solar wall is two planes of metal, per-forated on the outside, which draw air inward to be naturally preheated in the colder months, greatly reducing reliance on traditional heating methods. additionally, some of the air from within the building that has already been heated is recaptured and recirculated, mixed with fresh air. This further reduces the need for energy-hogging heating systems.

solar technology is also lining the roof of CanMeT, using uV energy to heat the water in the building. While solar panels are positioned to absorb the greatest amount of radiant energy,

many of these energy-efficient labs are themselves positioned to avoid taking on excess sun and heat.

“We’ve implemented solar shading to reduce thermal gain on specific orientations,” says siber. “The south and west faces are handled differently than north and east.”

Russ Chernoff, a leading Canadian designer of sustainable labs and the main lab consultant for Discovery Parks, a designer and builder of commercialization and research facilities in b.C., also

believes in the importance of taking the sun into account.“You need to take measures that control the sun coming into

the building,” he says. in 2003, Discovery Parks designed and built

Technology enterprise Facility iii (TeF3), the first LeeD-certified silver wet-lab research facility in Canada.

“in those days, people were saying that you couldn’t do a LeeD lab building. Too much air and energy is used in labs,” explains Chernoff.

by implementing the features that were available at the time, such as dual-flush toilets, waterless urinals, low-flow fume hoods and an energy-efficient mechanical

system, TeF3 became not only the first LeeD silver lab in Canada, but the fourth building of any type in all of Canada to meet the stringent requirements.

Considering how unfathomable a LeeD silver building was

just seven years ago makes the LeeD Platinum certification of CanMeT MTL all the more praiseworthy.

All in the detailsTechnology and building and design techniques that are utilized today give new buildings an edge in meeting high sustainability standards. However, there are massive energy costs associated with the construction of a new building.

gReeN is more than a trendy word.

McGill University’s Life Sciences

Complex employs energy-efficient

windows and lets natural light flood

through the building, reducing the need for overhead lights.


Green Report

To this end, Chernoff believes there is a critical question that must be asked.

“is there an existing building that i can do this in?”Many elements in a new sustainable building can also be

implemented in existing buildings. Low-flow or dual-flush toilets, energy saver windows, low-flow fume hoods and advanced mechanical systems can be brought in.

some old buildings cannot be salvaged, but some may just require a little elbow grease.

“if your envelope is a disaster, whether through deterioration of materials—if it’s leaky in terms of air and heat—there’s a point where you’re virtually rebuilding anyway. if you’re spending more resources and energy to save something like that, it’s not the good decision,” says Chernoff.

Carleton university’s newly rebuilt steacie superlab, for example, is one of the cases where an existing building was prime for upgrading.

“With this project, we tried to keep as much of the original building as possible,” explains Darrell Degrandmont, an architect with HoK, the firm responsible for the restructuring of the build-ing.

existing exhaust systems were reused, thereby reducing waste from inside the building and energy and resources that would be spent manufacturing and implementing a new system.

Hazardous materials, such as asbestos and mercury, had to be

What is LeeD?the Leadership in energy and environmental Design (LeeD) green Building Rating System is a third-party certification program and an internationally accepted benchmark for the design, construction and operation of high-performance green buildings.

Buildings gain credits relating to sustainable site develop-ment, water efficiency, energy efficiency, materials selection and indoor environmental quality.

Certification is based on the total point score achieved, fol-lowing an independent review and an audit of selected credits, and there are four possible levels of certification (Certified, Silver, gold and platinum).

the system includes 70 total available points. Certification can be achieved by obtaining 26 points. Silver and gold certi-fications require 33 and 39 points respectively, and platinum requires a score of 52.

there are no requisite standards for labs specifically, and so they must meet the same standards as a new construction commercial building.

For more information, visit the Canada green Building Council at www.cagbc.org/leed/what/index.php

McGill University circulates collected rainwater through its green roof and into the washrooms.


lab spotlight

removed and safely disposed of. The process for removal and disposal of materials from within the pre-renovation steacie superlab was energy and time-heavy, but in the grand scheme of this project, proved to be a relatively negligible cost.

“The embodied energies to actually build a new building from the ground up is incredible,” says angelo Montenegrino, a senior archi-tect at HoK. “any opportunity to upgrade existing buildings, anything we can do to increase the energy efficiency of a building, we want to do that.”

another goal with the superlab was to make it as versatile as possible, adding some depth to the notion of sustainability.

“When we did the superlab, we had a goal of trying to make it as flexible as possi-ble,” says Degrandmont. “The school needed to be able to manipulate or change things if they ever needed to without causing any sort of noticeable disruption.”

in this case, most services run through a main line above the work area of the lab and can be easily disconnected or relocated anywhere along the line.

What can be left out?This is a trend seen throughout the sustainability movement, aim-ing for longevity of buildings and limiting resources that will be necessary for changes down the road.

“These buildings, they’re going to be here 60, 80 or maybe even 100 years down the road. People are going to be changing

within these buildings. We have a great opportunity when creat-ing these buildings to keep the cost down for making those changes, minimizing the amount of removal to the landfill of materials and products that are in the building,” says Chernoff.

This means leaving out equipment that is not needed. not every suite within Discovery Parks’ affiliated buildings will need every ser-vice, for example.

“if we don’t put something in, we’re not even taking the resources out of the planet to get into the building in the first place,” says Chernoff.

in a traditional laboratory building, floor-to-floor heights measure around 15 feet. in TeF3, floor-to-floor height is 13 feet. This was achieved by implementing an umbilical cord system, similar to the steacie superlab,

where tie-ins to all systems are tightly contained.“That is an immense volume of material saved in construc-

tion,” says Chernoff. “This is also a huge gesture towards savings on the volume of air that you have to heat and cool over the life of the building.”

For building designers, leaving fancy design elements out of the laboratory is an indirect way to reduce waste.

“if you’ve got a building with a lot of stylish curves and inter-esting design elements, it may not be as sustainable as something more straightforward,” says Chernoff. “With oddly shaped spaces, it is difficult to find furniture and whatnot to fit properly. The design of the building could result in tenants throwing out exist-ing furniture, and in that way the building has caused waste.”

people often don’t even have totuRN oN the lights.

Once completed this fall, the CANMET MTL facility on the grounds of McMaster University will be the only LEED Platinum Certified lab in Canada. Solar power plays a significant role in reducing this building’s reliance on traditional energy.


Green Report

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the 2030 ChallengeIn 2002, esteemed u.S. architect edward Mazria, chal-

lenged the architecture and construction communities to adopt a series of consumption-reduction targets for new and renovated buildings. Because of his stature in the architec-ture world, many of his colleagues have taken this challenge to heart, even those who design energy-heavy laboratory buildings.

In this, he called for all buildings to be performing 60 per cent better than the model national energy code for build-ings. He believed that by 2015, the goal should be to reach 70 per cent, 80 per cent by 2020, 90 per cent by 2025 and carbon neutrality by 2030.

As a point of reference, the CANMet MtL building at McMaster university is targeting the 70 per cent mark by utilizing a complex system of solar and thermal energy, high-efficiency systems and high-quality building compo-nents.

“Some buildings, office or white-collar buildings, could easily meet that with the right team designing them,” says Birgit Siber, an expert in green design with Diamond and Schmitt Architects. “But with lab buildings, that’s incredibly difficult to do. you really have to push the envelope.”

the human factoranother thing labs are choosing to leave out, or at least reduce the presence of, are walls. They limit the penetration of natural light throughout a building, and a lack of natural light can have a dis-cernible effect on the occupants of the building. sustainable labs are not only aiming to be environmentally friendly, but to be employee-friendly as well.

“our challenge with the steacie project was to take four class-rooms that were dark and depressing and not very functional, and to turn them into this larger single room that enabled students to actually see and move around and have the professors teaching in a positive environment,” says Montenegrino.

The number of fume hoods in the superlab was doubled during renovation, but by using low-velocity glass fume hoods, the energy costs stay down and the natural light that is filtered into the lab from surrounding offices is not diffused by opaque surfaces.

During the renovation, mini-labs that would house researchers for longer than a few hours at a time were created on the perim-eter of the building, surrounding the superlab at the centre.

“in these labs, people often don’t even have to turn on the lights,” says Degrandmont.

The footprint for the CanMeT MTL building is roughly the size of a football field, according to siber, “Yet, the building will be infused with daylight; all 160,000 square-feet,” she says.

Creating more sustainable facilities is now on the mind of many professionals in many fields. Laboratories, being the energy consumers that they are, and on the forefront of science, can put a big dent in Canada’s energy consumption and show others what’s achievable.

“it’s incumbent on every one of us on the planet to find ways to reduce our footprint,” says Chernoff. “Labs are energy hogs, and we need to find ways to deal with them in particular. it doesn’t

just save money, but it reduces Co2 emissions, creates a healthier working and living environment. it’s a trend we will see more of because we have no choice in the matter. it’s not responsible for a design professional to ignore that. as far as i am concerned, this is a professional mandate.” LB


A work in progress: Dr. Andrew Potter, Director of

the Vaccine and Infectious Disease Organization in

Saskatoon, stands in front of the newly constructed CL3

facility in November.

lab spotlight

Vaccination has saved more lives than any other healthcare intervention. its effectiveness and low cost have made it essential to maintaining public health. over the past century,

smallpox has been eradicated, and the suffering and death caused by more than 30 other infectious diseases, including typhoid, diphtheria, polio, measles, mumps, and rubella, have been drasti-cally reduced. These are no small feats.

This is all according to the Canadian institutes of Health Research (CiHR) in its new report, Vaccines for the 21st Century: Taking Canada to the Next Level.

CiHR has identified research into vaccines as a priority for a variety of reasons. interest in vaccine research and development is

BugstheBeating

VIDO-InterVac will

continue Canada’s rich

history of research into

vaccines and infectious

disease with a new CL3

facility opening in 2011

By Theresa Rogers


intensifying. This, it says, is due to a dearth of vaccines for several major diseases; a lack of new antibiotics to fight infections; threats from emerging infectious diseases and bioterrorism; new uses for vaccines (e.g. to prevent and to treat cancer); renewed interest in global health; and a need to maintain national capacity.

Canada has always been at the forefront of vaccine research and development. LAB Business recently spoke to Dr. Andrew Potter, Director of the Vaccine and Infectious Disease Organization in saskatoon and home of the international Vaccine Centre (ViDo-interVac), about the new $140-million Containment Level 3 facility set to open in 2011. ViDo-interVac will represent the largest vaccine research investment

ever in Canada, which it says will enhance Canada’s capacity to develop vaccines and new methods of delivery for humans and animals.

Opening day is still more than a year away, but what will the new day-to-day look like?i could give you a potential list of research projects that will likely be undertaken within interVac, and that list will include swine and avian flu, in particular H5n1. We work on influenza now but we do this work in collaboration with the national Microbiology Laboratory in Winnipeg. our list of research projects will also include prion diseases such as bse in cattle and chronic wasting disease (CWD) in deer and elk. We have active programs for both of these Level 3 diseases but unfortunately we can’t do the vaccine testing until interVac is open.

Have you been doing any work around H1N1?sure, we’ve done a lot of work with H1n1. as far as an animal

disease, H1n1’s been around for a long time and there are a lot of varieties with H1n1. We’ve published work about the experimen-tal vaccines that we’ve developed, and when the outbreak started in the spring, we shifted some of our efforts to the new variant. That said, we are limited by the absence of containment facilities like interVac. We also have an active vaccine program related to Hepatitis C, but there again, you can only take research so far before you’re blocked by the inability to actually do work with the virus itself. The same roadblock exists for research involving tuberculosis.

How did you function so long without this type of a facility?We’ve done it because we’re a very collabora-tive organization. We have partnered up with people who either have access to the facilities or have partners that have access to the facili-ties. We have partnerships all over the world, in fact, on every continent with the exception of antarctica, and that includes groups with very good Level 3 facilities.

What would you tell Canada’s life sciences community about the lab? number one, construction is proceeding well and when it’s commissioned we would wel-come user applications from anybody from around the world. number two and most importantly, from an academic perspective, it opens up research horizons in a huge way. it’s amazing how many grant applications going to the Canadian institutes of Health Research rely on access to a facility such interVac, yet people don’t have access at the time of writing

the grant. number three, Canadian companies can gain a com-petitive advantage with research at interVac. Companies are wel-come to come in, as are academic and government researchers, and no single company justify building this type of facility. Given this, i think interVac offers a competitive advantage to our part-ners in the private sector.

I read that you want to be “a key player in Canada’s vaccine preparedness strategy.” How will you achieve this?i think anyone who’s followed the H1n1 story knows we’ve been reactive. We haven’t had a proactive stance on what are we going to do in the future when disease outbreaks occur, and they will come up. i would have thought we would have learned a lot from saRs about infectious diseases, what they can do, and being prepared for the next one. When i look at our response to H1n1, however, i can see very clearly that that hasn’t been the case as we’re all over the map with our response. i don’t know if there’s going to be another thing like saRs but there’s going to be

Green Report


lab spotlight

another emerging infectious dis-ease. no question about it; i just don’t know what it’s going to be. When you have the infrastructure, supporting networks and the tech-nologies to develop the interven-tion strategies, you’re then in a position of strength to work from. That’s what ViDo-interVac is all about. We do our own research here, primarily in platform tech-nologies that can be applied to any disease, and then can advance this research within the research the networks we have and are building. Canada is too small a country for us to go our own way and do our own thing in individual laboratories. We’ve got to work together.

How long does it take to develop these vaccines?it depends on the agent. influenza doesn’t take all that long at all because you simply plug it into an existing production system. in the saRs case, we had vaccine candidates for saRs ready for Phase 1, 2, and 3 within a year and a half. That’s a remarkably short time in the vaccine field as development of a new normal vaccine can typically take anywhere from 10 to 25 years to get a fully licensed product. obviously, this type of timeline is not con-ducive to dealing with emerging and infectious diseases.

Are we developing new policies and processes then along the way as well?i think we are, and i applaud the regulators for doing this. Certainly with H1n1, we are developing new ways of doing things because we can’t wait.

It’s generated a lot of discussion in the public and you’re publicly funded. I imagine that would help you in the running and the point of view of the facility in the public’s eyes. It’s not a tough sell right now.not a tough sell right now. When it comes to infectious disease and Canada’s role on the international stage, since the early days with small pox and polio and all the way through, Canada has done some amazing work, both in the public and private sectors. it’s a story that needs to get out to people and it’s a story people love to hear.

Are there any strengths or weaknesses you can identify with the facility?With the facility, there are a lot of challenges from the financial perspective. it’s an incredible facility and cost-wise, we are going to have an ongoing challenge as it’s going to be very expensive to

maintain. The same challenges exist for conceptually similar ones across the country. With interVac as one of the top 10 science facilities in Canada, and probably one of the top six in terms of the value of it, Canada is recognizing that we need this type of facility and that government needs to support this type of research infrastructure. Determining a way to fund this type of facility is absolutely critical, and is likely best addressed with a partnership

Building it GreenWhen constructing the InterVac facility, builders utilized a number of approaches to make the building as easy on the environment as possible. • Glycol heat reclaim loops for all exhaust air• Scheduled night shut-offs for air systems in non-containment

areas• High-performance window glazing systems for minimizing

heat loss/gain while maximizing natural daylight into building• Daylighting control for perimeter corridor and office lights• Full glazing on perimeter office walls and windows into labs

to maximize light penetration• Use of low maintenance/xeriscape landscaping materials• Use of polished concrete floors in common areas (less materials

used in construction, no maintenance required)• Use of local stone for interior and exterior finishes (less transport)• Use of oversized air systems (run slower and use less energy)• Ability to shut down experimental areas when not in use• Building Control Management System closely monitors all air

flow and temperatures• Redirection of building construction waste to alternative

locations whenever possible (recycling, re-use)


• InterVac Construction Cost: $140 million• Annual operational funding for VIDO-InterVac: $25 million• Total capacity: 245,000 square-feet• Technology in 8 commercialized vaccines, six of which were

world firsts• Awarded more than 80 U.S. patents• Employs more than 150 people; planning to hire another 50

of all levels of government, the private sector and anybody else that wants in.

You’re hiring 50 new positions. Is it easy or tough to find people?it’s always tough to find great people. We’ve been remarkably suc-cessful in the past and hope to be able to continue that success, but it’s tough. it’s a competitive field these days and there are a lot of good jobs available for the right sorts of people. What we try and do is offer them the ability to come here and essentially reach their full potential. We don’t put any constraints on people; rather they’re encouraged to go as far as they can with their research and what they want to do.

What do the next five years look like?Lots of fun. The possibilities are mind-boggling so we’re really, really excited. i think you’re going to see a lot of acceleration with

research programs already underway, plus you’re also going to see a lot of new things. it’s really exciting as this applies to Canadian research and around the world. This is the sort of thing that keeps us going.

ViDo-interVac will be one of the largest Containment Level 3 vaccine research and development facilities in north america. Visit www.labbusinessmag.com for

summaries of some of the research already being conducted at ViDo, in the researchers’ own words.

LB

Green Report

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suzuki comment

Healthcare Pros Signal Importance of Keeping Environment HealthyBy David Suzuki

You can’t have healthy people without a healthy environment. We know that pollution and environmental degradation can

cause a range of health problems, from mild stomach ailments to birth defects, cancer, and death. This creates strain on the health-care system and ends up costing us all.

according to some estimates, adverse environmental exposures in Canada are associated with up to 25,000 deaths, 194,000 hos-pitalizations, 1.8 million restricted activity days for asthma suffer-ers, and 24,000 new cases of cancer each year, with costs as high as $9.1 billion a year. Globally, the World Health organization estimates that environmental risk factors play a role in more than 80 per cent of the diseases reported by the organization and that one-quarter of all diseases and deaths—one-third for children —are directly related to environmental causes.

The health sector itself, which contributes about 10 per cent of Canada’s gross domestic product and employs close to 1.7 million people, creates considerable waste and pollu-tion and consumes a lot of energy. Recognizing the connection between healthy people and a healthy environment, leading health-profes-sional organizations have joined together to call for an environmentally responsible health sector in Canada.

The Canadian Medical association, Canadian nurses’ association, Canadian Dental association, Canadian Pharmacists’ association, and more, with help from the David suzuki Foundation, recently voiced a commitment to make the sector greener and to get gov-ernments to consider the links between health and the environ-ment when making policy decisions.

beyond cleaning up its own act and trying to get the govern-ment to pay more attention to the environment, the sector hopes to set an example for others to follow. and, as healthcare provid-ers, they hope to encourage all Canadians to become more environmentally aware and thus healthier.

Leadership from this sector is much needed and welcomed. a recent poll shows that health professionals are among the most trusted community leaders. and we all rely at times on our healthcare institutions and facilities. Many people in the health-care sector are also guided by a principle to “do no harm.” one thing this suggests is that institutions devoted to healing should not be significant consumers of resources and sources of environ-

mental harm through air and wastewater emissions, hazardous- and solid-waste generation, greenhouse gas emissions, and toxic chemical usage. Thus, being green has a symbolic and practical significance for institutions.

Greening their own operations is a great start for healthcare institutions, but health professionals have been demonstrating environmental leadership in the wider community as well. For example, the ontario College of Family Physicians and the Registered nurses’ association of ontario advocated for a recent ban on “cosmetic” or unnecessary lawn and garden pesticides in the province.

as we see so often when it comes to measures to protect the environment, it makes good economic sense to spend money on addressing environmental factors to prevent illness and disease,

too. in some cases, those measures are fairly straightforward. Removing lead from gasoline has substantially reduced the incidence of mental retardation caused by lead exposure. and u.s. authorities have estimated that regu-lations introduced in 2005 requiring american power plants to reduce air pollution will pro-vide between us$85 billion and us$100 bil-lion in annual health benefits by 2015, an amount roughly equal to 25 times the cost of implementation.

some issues are more complicated. Global warming is associated with a wide range of concerns related to health and the environment, from contaminated water supplies to food shortages.

The organizations supporting the greening of Canada’s health sector recognize this, and are encouraging the use of energy-conserving techniques and products in health facilities, along with reducing waste through reusing and recycling and finding sources of materials that use less packaging.

We have many reasons to protect the environment. as health professionals have recognized, two big reasons are to protect our health and to save money. We can all follow their example by doing whatever we can to reduce our negative impact on the planet. after all, healthy environments lead to healthy people and healthy economies.

Dr. David Suzuki is a scientist, broadcaster, author, and chair of the David Suzuki Foundation. Learn more at www.davidsuzuki.org.

Institutions devoted to healing should not be significant

consumers of resources and sources of

environmental harm

Green Report


lab Reports

For many laboratories, funding is very rarely abundant. Lab managers must often make decisions concerning which equip-

ment must be replaced and which will need to be stretched for another year, possibly placing limitations on lab productivity. Consider stretching your lab’s budget significantly further this year by investigating whether or not the equipment needed in next year’s upgrades can be purchased second-hand. You’ll not only be saving money, but also the environment.

“Right now, i’m going through a sale with a piece of equip-ment called a LeaDseeker, which is a product from General electric,” says Chris ayotte, Director of operations at equip-ment-seller Harlow scientific. “To buy this piece of equipment new, a lab would be looking at around $200,000. We, on the other hand, are making this deal for $85,000. We got this at a good deal ourselves and have been able to pass those savings on to a good client of ours.”

Harlow scientific buys, sells, rents and stores gently used sci-entific equipment, a niche of the lab industry that has grown increasingly appealing over the last few years.

“There is an obvious answer as to why people are looking to this option,” says ayotte. “People want to save money.”

Recently, Kristina Macnaughton, a research technician at the university of alberta, needed to make the most of her money.

“i was working for a brand new investigator, and when he got here, he was applying for grants. our institution gives a bit of a startup fund to get equipment for the lab, but when you have to buy everything from pipettes to large machinery, it gets pricey,” she says. The only way to realistically and satisfactorily furnish the new lab was to go second-hand.

ayotte agrees that for some labs, even saving a few thousand dollars can mean the difference between getting up and running, or not.

“We sell an instrument called an M5 from a company called Molecular Devices. We sell a 2008 model like-new for $35,000,” ayotte says. “They are quoting an unused model out for $42,000 to $45,000. People who have the money will shrug off that $7,000 or so and go for the new model, but for a smaller lab, $7,000 is $7,000. For many startup companies or small laboratories, that’s still significant. it amounts to money that can be spent on reagents or other stock.”

One Lab’s Trash is Another Lab’s TreasureSecond-hand equipment is a green and cost-effective way to furnish your lab

By Jason Hagerman


Finding equipment and setting the priceCompanies like Labequip Ltd.—an equipment reseller—and Harlow are constantly on the lookout for equipment that can be re-used.

“We get some of our equipment directly from manufacturers, or from dealers as overstock or demos,” says Mark Rafman, President of Labequip.

a lab may be changing its experimentation process and will no longer need a particular piece of equipment; the lab may be down-sizing, cutting costs by removing resource-depleting equipment; or they may have had to shut down entirely—unfortunate for the lab, but fortunate for Harlow, which buys entire labs’ worth of equipment.

second-hand suppliers generally buy equipment for cash out-right, however, suppliers will also broker items and will take equipment on consignment.

“some labs are just looking for space right away. We’ll take the equipment into our facility, take it under our wing and market it on a consignment basis,” says ayotte.

after acquiring the equipment, second-hand suppliers take into account a number of factors in order to set a fair price.

“The price we pay is one of the main factors that play into the equation,” says Rafman. The age and condition of the equipment and overhaul costs (including parts and labour) play into the cost as well. if the manufacturer no longer sells a model of equipment, costs are compared to a reasonably similar product from that same manufacturer, and if an item is of interest only to a narrow, spe-cialized customer base, price is altered further.

“We decide on the pricing because we’re experts,” adds ayotte. “We know what’s out there, we know how much of it is out there, and supply and demand does play a role.”

Why not go directly to the lab selling the equipment?if prices take into account supply and demand and niche products, why would a lab manager not just find somebody looking to clear some space in their lab and buy directly from them?

“Labs in this situation are tough to come by,” ayotte says. Rafman adds, “The biggest advantage is availability. if you are

really lucky, your colleague down the hall may have the right type, size and model of instrument that you’re looking for. in reality, the odds are against that. We have over 6,000 items in stock, all cata-logued, photographed, described and indexed in three different ways, easily accessible on our website.”

it can be boiled down to the fact that there are entire busi-nesses modeled around finding this equipment, and they are much better at it than the average person. if you do manage to find the equipment you’re looking for without the help of a sec-ond-hand supplier, what assurance do you have that the equip-ment is in working order, and worth the price that you’re paying?

Is reliability an issue?a roadblock to many lab managers is the fear of picking up poorly functioning second hand equipment. new lab equipment, according to ayotte, has a typical return rate of around two per cent.

“With the used equipment that we refurbish and sell, we have a return rate of less than that,” he says.

in order for equipment to be allowed to leave the Harlow warehouse, it needs to run like new. Technicians bring any piece of technology up to factory specifications, completely recertifying the equipment as though it had never been used before.

“We try to buy equipment that is from one to five years of age, so that we can keep repair costs down and the cost to the end user down as well,” ayotte says.

Companies like Harlow and Labequip consider cosmetic appearance, but the emphasis is on operational accuracy when refurbishing equipment.

Reputable dealers offer warranties on the refurbished equip-ment, giving buyers a safety net should that one-in-a-hundred faulty machine fall into their hands.

“Warranty is a crucial consideration when buying from us versus an auction or end user,” says Rafman.

Three months is usually long enough to determine whether a piece of equipment is functioning properly, and is a good length of time for second-hand equipment to be covered by a warranty, says ayotte.

Peace of mindKnowing that re-used equipment is certified, running properly and backed up by a warranty will give the lab manager peace of mind, as will knowing that purchasing second-hand equipment is a great way to protect the environment.

all manufacturers observe best practices and environmental standards when it comes to decommissioning equipment, but labs can help them do better.

“Throwing something out is basically keeping it from going back into circulation, and that amounts to wasted resources mak-ing it in the first place,” says ayotte. Companies like us keep that equipment out of the landfill.”

“by dismantling equipment, recycling for its constituent mate-rials, thousands of dollars are converted to tens of dollars, in effect a process of reverse alchemy,” says Rafman. “Refurbished equip-ment saves in many ways—money, carbon footprint, energy use in creating the raw materials, manufacturing the product and ship-ping it. There is also an indirect benefit in that more money is available to purchase other goods, stimulating the economy.” LB

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tech watch

Automationtoday’s labs operate at extremely high volumes, pushing technicians to the limit of their abilities and causing

stress in both workers and managers. This can result in burnout, faulty data or test results, and more. Dealing effectively with today’s high expectations of throughput sometimes requires more than the human worker can offer. Thankfully for lab managers looking to increase laboratory efficiency, automation technology is an afford-able and reliable way to deal with increased laboratory workloads without placing more weight on the shoulders of workers. automation technology not only increases lab efficiency by performing repetitive tasks more quickly and precisely than lab workers, but by taking these tasks out of the hands of the technician, it is allowing them to focus on other elements that do require the human touch. Following are five examples of automation technology that may be the difference-maker in your lab.

Centred on the new Thermo scientific orbitor microplate mover and powered by the Thermo scientific Momentum 2.0 laboratory workflow software, Thermo Fisher scientific’s new automation solu-tion offers advanced user control and standardized real-time, data-driven deci-sion making. This combination of robot-ics, peripherals and scheduling software is ideally suited to small, flexible automated systems or dedicated benchtop applica-tions. The new orbitor benchtop mover provides industrial reliability with robust plate motion and control. as a central mover with the ability to rotate 360

degrees, the orbitor can con-nect a broad range of scientific devices, making it an extremely versatile platform. With inte-grated stack and random access storage standard, as well as re-grip and plate de-lidding, the orbitor serves as a low-cost integration solution. Flexible shelving and a small footprint make the orbitor ideal for practical online/offline use and rapid instrument swap out. The Momentum 2.0 software facilitates predictive modelling of accelerated dynamic processing schedules,

The agilent 7693a series automatic Liquid sampler (aLs) offers substantial gains in throughput, flexibility, sample preparation automation and serviceability for all current benchtop agilent gas

chromatographs (GC). The 7693a replaces agilent’s 7683b with a completely new design. The new aLs is modular, letting users configure the exact autosampler they need—starting with a basic injector with a 16-sample turret and later adding additional capabilities as needs expand.

options include a second injection tower, a 150-vial sample tray and a vial heater/mixer/barcode reader for long, unattended operation. The self-aligning “plug and play” injector

mounts quickly without tools and can be moved from one inlet to another, or even between GCs to accommodate changes in workloads and facilitate inlet maintenance. injection time of less than 100 milliseconds minimizes sample degradation and the

effects of needle discrimination. The new injector supports sandwich injection, which enables internal standard and/or solvent aliquots to be added to the syringe prior to

injection. The optional heater/mixer/barcode reader module can automate a number of pre-injection procedures, such as preparing highly viscous or slightly soluble samples.

www.agilent.com

New Platform for Benchtop Automation

eliminating a common compromise between efficient automation usage and unpredictable system behaviour.www.thermo.com/automate

New Speed, Sample Prep Functions and Flexibility


Control Company’s inexpensive Liquid alarm may be placed anywhere and used to detect when drums, tanks, flasks or beakers are close to overfilling. it’s the perfect reminder for unattended filling of any con-tainer. The moment a solution touches the sensor, the alarm sounds and a red LeD light flashes continually until the sensor is clear of the liquid. The sensor can also be placed on the floor to detect spills. The alarm will maintain a high decibel alert for more

than 30 hours. Position the detector on an overflow tube or near a pump to alert you when an accident is occurring. a 10-foot cable allows for flexibility and the unit itself has only a small laboratory footprint. use with aqueous solutions and liquids that don’t attack plastic. being battery-operated, the alarm sounds even during power outages and pays for itself by preventing just one ruined lab test. www.control3.com

essa’s wet chemistry cell is an automated system designed to efficiently and con-sistently prepare up to 300 laboratory samples for analysis. sample batches are controlled and recorded by the human-machine interface (HMi) system, which can process both normal batches or inte-grate with a LiMs system. Capped test tubes containing samples are placed in up to four racks of 50 into the system via access windows, which are electro-mechanically interlocked (as with all access points) to ensure optimum opera-tor safety. if a high-priority preparation is required, two additional trays of 50 test tubes can be added at any time dur-ing the run. These samples can be fast-tracked through the complete process.

During loading, a safety guard is acti-vated to isolate the operator from the moving robot. at the end of the extrac-tion process, the robot returns the pro-cessed test tube to its original rack posi-tion and the vials are placed into vial wedges ready for collection. a filled wedge can be removed from the cell at any stage without stopping production. once again, a safety guard is lowered to isolate the operator from the moving robot. it takes just under eight hours to prepare 200 sample vials for analysis. During the process, a control system monitors progress and incorporates alarm information, history and diagnos-tics. all data is easily exported to LiMs.www.essa.com.au

The epMotion 5075 TMX is the most flexible member of the epMotion family of automated pipetting systems manufactured by eppendorf, the company says. it includes an integrated TMX module to shake, heat or cool samples. The TMX module can be loaded and unloaded with the gripper. Pipetting to the mixer is possible before and after mixing steps. The TMX module is fully software-con-trolled enabling pipetting on other worktable positions while the mixer is in operation. in addition, eppendorf recently announced the latest version of its PC software for controlling the epMotion automated pipetting system. epblue iD incorporates new barcode management functionality to provide secure sample tracking. operating and programming is easy and fast—complex methods can be generated in minutes with intuitive menus and a tab-based structure that guides the user through the software functions. ease of use is capable through pipetting pattern recognition, a pre-defined labware database and built-in and organized liquid classes. This system has been developed specifically for users working in regulated areas where sample safety and the requirement to track and document each individual specimen are of paramount importance.www.eppendorf.com

Wet Chemistry Cells

Reduce Repetitive Tasks

Monitor Fluid Levels from Across the Lab

tech watch

Free LaborMetrohm titration systems automate all your tedious and time-consuming tasks.

And let’s face it, what lab couldn’t use an extra hand with much of the daily/routine work? Our systems can handle your sample preparation from start to finish, fully monitor and control every aspect of your analysis, and securely store your data for quick and easy recall. Results are fast and, more importantly, always accurate and consistent.

Easy-to-use systems can:

•Automatically weigh, homogenize, filter and dilute

•Automatically pipet samples from 200 µL to 100 mL

•Automatically process from 12 to 141 samples

•Always be customized to meet your needs

•Always be counted on: 3-year warranty

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lab ware

Portability in a ULT FreezerCanadawide Scientific introduces three new portable, ultra-low temperature solutions for a large number of applications. Small both in size and in power consumption, these portable ULT freezers weigh about 35 pounds and draw extremely low power. Highly flexible, the units are suitable for use under the lab bench, but can also be transported by researchers to the field for sample collection. Two digital models come in temperature ranges of -40 to 10 C (ideal for environmental and research applications) and – 80 to –20 C (for pharma and lab). The analogue model ranges in temperature from –18 to 10 C (useful for clinical applications).www.canadawide.ca

Ergonomic MicrotubesBiohit, Inc. recently introduced its new ErgoTubes. These microtubes are designed with a patented flip cap, which significantly reduces strain and effort during use. This feature assists in opening the ErgoTubes more safely than traditional micro centrifuge tubes. The ErgoTube meets today’s demand for ergonomic, safe and functional tubes for use in centrifugation, sample prep, boiling and storage. Biohit ErgoTubes are RNase, DNase and Pyrogen-Free. They are available in clear as well as eight colours. Sizes include 0.5 ml, 1.5 ml and 2.0 ml. All tubes are packaged in tamper evident re-sealable bags for user and sample protection. ErgoTubes are excellent for centrifugation, sample prep or storage. They are made of virgin polypropylene and have a frosted area for marking on both the cap and the side of the vial. www.biohit.com

Fast, Effective Sample PrepThermo Fisher Scientific announces the availability of the new Thermo Scientific Aspire Protein A, Protein G and IMAC Cobalt Chromatography Tips. Aspire proteomic tips are 1 ml pipette tips embedded with various Thermo Scientific Pierce resins, including immobilized Protein A Plus, Protein G Plus and HisPur Cobalt resins. These pipette tips utilize colour-coded purification workflows and allow accelerated sample preparation without compromising yield or purity. Up to eight samples can be processed in parallel within 20 minutes without the need for cen-trifugation. Aspire chromatography tips allow for high-quality, cost-effective sample prepa-rations in less time.www.thermo.com/aspire

Earth Friendly ElectrodesMettler Toledo’s new electrodes are free of lead, mercury and other hazardous sub-stances prohibited under Restriction of Hazardous Substances in Electrical and Electronic Equipment (RoHS) and Waste Electrical and Electronic Equipment (WEEE) standards. Available in a variety of styles, including refillable and low-maintenance versions, InLab electrodes are designed to meet the most stringent requirements of today’s laboratory. Mettler Toledo offers electrode products for a variety of applica-tions, such as pharmaceutical samples, chemicals, pure water, cosmetics and food. Products include the InLab Micro Pro, a TRIS-compatible micro-electrode with long-life Argenthal reference and an integrated temperature probe; the InLab Viscous, an electrode with an easy-to-clean design and an overpressure electrolyte system, guaran-teeing electrolyte discharge while eliminat-ing junction contamination issues.www.mt.com

Reduce Distortion, Maximize VisionSperian Protection announced that its flag-ship brand, UvexR, launched the new Uvex PrecisionProT style of safety eyewear. Uvex PrecisionPro’s frameless design and precise optics maximize vision and reduce distortion for jobs where seeing every detail in perfect clarity is critical. The style is ideally suited for applications such as quality control, inspection, lab work, aerospace, fine main-tenance, cleanrooms and mechanics. Uvex PrecisionPro is available with Uvex’s new Supra-DuraT anti-scratch coating that pro-vides five times more scratch resistance than other coatings on the market or with UvextremeR anti-fog coating. The eyewear meets both ANSI Z87.1- 2003 (high impact) and CSA Z94.3 safety standards and comes with a lifetime frame guarantee.www.uvex.us


The “Solution” to Gene Transfer DifficultiesBTX introduced its new BTXpress High Performance Electroporation Solution. The solution enhances gene transfer into mammalian cells transfected by electroporation. A single buffer solution developed to quickly and efficiently deliver genes into mammalian cells previously considered “hard-to-transfect” by chemical or other non-viral methods. BTXpress supports high efficiency transfection of DNA or siRNA into a broad range of cell lines while maintaining critical cell viability. Combining the performance of the BTXpress electroporation buffer with the versatility of the BTX electroporation systems provides a solution to overcome the difficulties associated with transfecting mammalian cell lines.www.btxonline.com

Latest Weapon Against PandemicsOf all common surfaces, keyboards are one of the most germ-infested—filthier even than public toilet seats according to many studies. In hospitals, keyboards are known to spread infection more than any other surface. Considering more than 100,000 North Americans die from hospital-acquired infections every year, Cleankeys could save lives. Clinical trials prove that a single wipe with a disinfecting cloth on Cleankeys’ smooth surface kills 99 per cent of all bacteria. The same test on standard plastic and rubber keyboards eliminates less than five per cent. www.cleankeysinc.com

L I S T O F A D V E R T I S E R S & W E B S I T E S

ABIC ............................................................Page 6 .............................................. www.abic.ca/abic2010Brain Tumour Foundation ............................Page 10 ................................................www.braintumour.caCaledon Labs ..............................................Page 19 ............................................ www.caledonlabs.comEppendorf ....................................................Page 35 ................................................www.eppendorf.comFisher ...........................................................Page 2, 28 ................................................. www.fishersci.caResearch Store ...........................................Page 4 .................www.labbusinessmag.com/researchstoreMetrohm(Brinkmann) ...................................Page 31 ............................................www.metrohmusa.comMiele Professional .......................................Page 23 .................................................. www.miele.ca/lab1VWR ............................................................Page 24 .......................................................... www.vwr.comWaters .........................................................Page 36 ..................................................... www.waters.com

Storage Made EasyA full line of colour-coded folders and specially designed boxes for safely, storing and transporting specimen slides used by school, university, and research laborato-ries, hospitals, clinics, and police crime units, was introduced by Mason Box Company. These boxes are designed for safely cataloguing, storing and shipping specimen slides. They include colour-coded slide folders for separating slides by sub-ject, date or department; rigid cardboard mailing boxes with slotted foam inserts and wire tabs that protrude through the top, bend over and can be taped for tam-per-evident packaging; and plastic boxes. Designed for standard three-inch by one-inch slides, they are also ideally suited for storing microscope optics.www.masonbox.com

Trace Moisture Standards in Reactive GasKin-Tek Laboratories Inc.’s Span Pac H2O-R Moisture Standards Generators create known calibration standards of trace moisture in reac-tive gases such as chlorine and HCL. These systems use Trace Source permeation tubes to dynamically add a known amount of water vapour to a flow of dried reactive matrix gas. Concentrations from < 10ppb to over 100ppm are possible by selecting suitable permeation tubes. At any concentration level, multi-point calibrations over a 400:1 range are comfortably achieved. Applications include on-site moisture monitor calibration and production of controlled atmosphere for catalysis studies, corrosion rate studies and filter capacity tests.www.kin-tek.com


sitting with

Q: How long have you been involved in laboratory science? A: i graduated from the Michener institute of applied Health sciences (Toronto) in 1997, during the downsizing of healthcare. of my class of 12, i was the only one to find full-time work six months after graduation. i started work at the Michener in the Prep Team, sup-porting the Medical Laboratory science program in 1997 and stayed there until 2003.

Q: What got you interested in this in the first place? A: My passion for science started like all of us—in high school, with science teachers who simply loved what they did. i was fortunate enough to have a co-op placement at our local Public Health unit in Peterborough, ontario and when i asked about the training need-ed—they sent me to the medical laboratory technology program.

Q: What is the most interesting piece of equipment in the lab, in your opinion? A: it has to be the “bellydancer” in Genetics. While i didn’t train in clinical genetics, the school i went to had this program, and we had the chance to use this equipment once. Whenever i would go into the genetics lab, this was a mesmerizing movement. not the most technical, but certainly the most interesting to me.

Q: If you never had to work another day in your life, what would you do? A: even if i win the lottery, i would still work in the profession in some capacity, but i would take some time to read all the books piling up in my house (i have more than 100 to be read), and do more volunteer work.

Q: If you could travel to three places in the world, where would you go and why? A: egypt, the birthplace of civilization to see the pyramids, The Forbidden City and the Great Wall in China because of the politics and engineering feats, and Hawaii for the beauty and heat.

Q: Do you think it is acceptable to eat breakfast for dinner? A: absolutely. Life is too short to do, eat and say what others always expect from you. so, if you want bacon and eggs (or turkey bacon and egg whites) for dinner, go ahead, i am not judging you.

Q: What is your favourite winter Olympic event? A: Hockey—men’s and women’s. it is in my genetic makeup being a Canadian and the sister of a die-hard Habs (Montreal Canadiens) fan.

Christine Nielsen recently took up the position of Executive Director with the Canadian Society for Medical Laboratory Science (CSMLS). Read more on page 9.

Christine nielsen

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