University of Pittsburgh

Mark J. GartnerHarvey S. Borovetz

Workshop on BME Teaching of Innovation, Design &

Entrepreneurship

• Two semester senior-level biomedical integrated product design course

• First semester• Computer aided engineering (SolidWorks)• Finite element analysis (ANSYS)• Computational fluid dynamics (Fluent)• Statistical design of experiments (DesignExpert) • Lectures focusing on fundamental components of

product design

• Second semester• Team design projects

– 3 to 4 member teams organized by post-graduation plans and common interest

– Project topics formulated by instructor and team – Team “advisor” selected based on needs of team,

expertise of advisor, and focus of project

University of Pittsburgh

BIOENG 1160/1161 Bioengineering Design I, II (MJG)

• Two separate, one semester, upper level elective courses

• Bioeng 1050• Topics: Heart, Lung, Blood Vessel• Term Project:

– Design a Pediatric VAD– Improve the Design of VADs or ECMO Based on the

Known Clinical Complications • UoP (& FDA) staff with industrial experience serve as

“advisers” & “consultants”

• Bioeng 1051• Topics: Kidney, Blood, Liver• Term Project:

– Design a Biohybrid Artificial Liver (starting point – existing BAL)

University of Pittsburgh

BIOENG 1050/1051 Artificial Organs I, II (HSB)

University of Pittsburgh

Overall Pump Design (www.kinderheart.com)

Describe particularly novel and/or effective methods you use to teach innovation &

entrepreneurshipBIOENG 1160/1161

• Initial survey of post-graduation plans and interests• Choice of deliverable

– Business plan -> entry into business plan competition– NIH-format grant (SBIR/STTR Phase I, R01)

• Market-based focus– Marketing, basic finance and accounting principles

instruction– Incorporation of market-based deliverables into project

• Marketing plan and strategy• Manufacturing plan

• Incorporation of organizational behavior principles– Personality determination– Dysfunctions of groups

• Cross-fertilization with MBA students at Katz School of Business at University of Pittsburgh

University of Pittsburgh

How do you measure outcomes?

BIOENG 1160/1161• Comparison of negotiated

deliverables in first semester with results in second semester

• Is the deliverable patentable or publishable?

• Feedback from advisor/independent reviewer (e.g., business plan competition coaches)

University of Pittsburgh

Describe a course project or exercise that exemplifies “best

practices”BIOENG 1160/1161

• Reverse-engineering/product dissection– Each design team dissects representative

products

• Requirement to observe similar product in clinical use – generation of human-factors related observations

• Comparative medical/non-medical design requirements– How do the critical elements of design differ

for a bone screw versus a simple fastenerUniversity of Pittsburgh