5th  Tropé-­‐Kolstad  meeting  Updates  in  Gynecologic  Oncology  

 

Friday  December  5,  2014  –  Oslo    09:00  –  18:00  

 

Sponsored  by  Inger  and  John  Fredriksen  Foundation  for  Ovarian  Cancer  Research  

 

                       

The  meeting  takes  place  in    the  Auditorium  of  Building  K,  Institute  for  Cancer  Research    

Oslo  University  Hospital,  the  Norwegian  Radium  Hospital    Oslo,  Norway

UPDATES INGYNECOLOGIC ONCOLOGY

5th Tropé - Kolstad meeting

Friday December 5, 2014 - 09:00 - 18:00

Sponsored byINGER AND JOHN FREDRIKSEN FOUNDATION FOR

OVARIAN CANCER RESEARCH

The meeting takes place in the Auditorium of Building K, Institute for Cancer ResearchOslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway

 

SCIENTIFIC  PROGRAM  DECEMBER  5,  2014  

 

09:00  –  09:05   Welcome  Dr.  Erik  Rokkones,  MD,  PhD,  Chairman  of  the  Department  of  Gynaecological  Oncology,  the  Norwegian  Radium  Hospital  (Norway)  

 Molecular  Characteristics  of  Ovarian  Cancer  Chair:  Dr.  Anne  Dørum,  MD,  PhD  (Norway)  

09:05  –  09:35   Chemoresistance  Markers  in  Metastatic  Ovarian  Carcinoma  Prof.  Ben  Davidson,  MD,  PhD  (Norway)  

09:35  –  09:40   Discussion  

09:40  –  10:10   Molecular  Predictor  of  Residuals  in  Patients  with  Ovarian  Cancer    Professor  Beth  Karlan,  MD  (USA)  

10:10  –  10:15   Discussion  

10:15  –  10:45   Impact  of  Oophorectomy  on  Cancer  Incidence  and  Mortality  in  Women  with  BRCA1  or  BRCA2  Mutation    Prof.  Pål  Møller,  MD,  PhD  (Norway)  

10:45  –  10:50   Discussion  

10:50  –  11:20   Coffee  break  

11:20  –  11:50   Does  Overlap  in  Molecular  and  Histologic  Subtypes  Support  New  Strategies  for  Clinical  Trials?  Prof.  Helga  Salvesen,  MD,  PhD  (Norway)  

11:50  –  12:00   Discussion  

 

The  5th  Tropé-­‐Kolstad  Lecture  Introduction:  Dr.  M  Bilal  Sert,  MD  (Norway)  

12:00  –  13:00   Epithelial  Ovarian  Cancer:  A  Real  Challenge  for  the  Next  25  Years!  The  Surgeon’s  Viewpoints  Prof.  Neville  Hacker,  MD  (Australia)  

13:00  –  14:00   Lunch    

 

Controversies  in  Ovarian  Cancer  Treatment  Chair:  Dr.  Tone  Skeie-­‐Jensen,  MD,  PhD  (Norway)  14:00  –  14:40   Neoadjuvant  Chemotherapy  in  Ovarian  Cancer  

Pro:  Professor  Beth  Karlan,  MD  (USA)  Con:  Prof.  Neville  Hacker,  MD  (Australia)  

 

14:40  –  14:45   Discussion  

14:45  –  15:05   Fluorescent  Lymphatic  Mapping  in  Gynecology  Prof.  Nadeem  Abu-­‐Rustum,  MD  (USA)  

15:05  –  15:20   Secondary  Cytoreduction  of  Recurrent  Ovarian  Cancer  using  Robotic  Platform  Dr.  Ane  Gerda  Zahl  Eriksson,  MD  (USA)  

15:20  –  15:25   Discussion  

 Ovarian  Cancer  and  Pregnancy  Chair:  Dr.  Janne  Kærn,  MD,  PhD  (Norway)  

15:25  –  15:45   Ovarian  Cancer  in  Pregnancy  Prof.  Frédéric  Amant,  MD,  PhD  (Belgium)  

15:45  –  15:50   Discussion  

 

Germinal  Cell  Tumors  of  the  Ovary  Chair:  Prof.  Vera  Abeler,  MD,  PhD  (Norway)  

15:50  –  16:10   Post-­‐Treatment  Fertility  and  Gonadal  Function  in  Young  Women  Diagnosed  with  a  Malignant  Ovarian  Germ  Cell  Tumor  (MOGCT)  During  the  “Cisplatin  Era”    Dr.  Olesya  Solheim,  MD  (Norway)  

16:10  –  16:15   Discussion  

 Prospective  Clinical  Studies  in  Advanced  Ovarian  Cancer  Chair:  Prof.  Bjørn  Hagen,  MD,  PhD  (Norway),  Dr.  Brynhildur  Eyjólfsdóttir  (Norway)  

16:15  –  16:45   Updates  of  the  Prospective  Randomized  Studies  in  Advanced  Epithelial  Ovarian  Cancer  in  the  World  Today  Professor  Gunnar  B  Kristensen,  MD,  PhD  (Norway)  

16:45  –  16:55   Discussion    

16:55  –  17:25   Coffee  break    

17:25  –  17:45   Summary  of  the  2014  MD  Andersson  International  Meeting  in  Ovarian  Cancer:  Emerging  Therapies  in  Ovarian  Cancer  Prof.  Nadeem  Abu-­‐Rustum,  MD  (USA)  

17:45  –  17:55   Discussion  

17:55  –  18:00   Closing  remarks  Professor  Beth  Karlan,  MD  (USA)  

 

 

Professor Ben Davidson, MD, PhD Oslo University Hospital, the Norwegian Radium Hospital, Oslo, Norway

Date and place of birth: September 23, 1964; Tel Aviv, Israel. Citizenship: Israeli Present position: Senior Pathologist and Head of Research, Department of Pathology, Oslo University Hospital; Professor, University of Oslo Education 2003-2004: Post-doctoral fellow at NCI/NIH, Bethesda MD 1998-2001: Ph.D. program, Norwegian Radium Hospital; Thesis defended 23/8/01 1986-1992: Medical studies in Sackler School of Medicine, Tel-Aviv University Brief Chronology of employment 2002-present: Staff pathologist, Department of Pathology, Norwegian Radium Hospital, Oslo, Norway; Sub-specialist in cytopathology and gynecologic pathology 1998-2002: Resident (combined with PhD program), Department of Pathology, Norwegian Radium Hospital, Oslo, Norway 1994-1998: Resident, Department of Pathology, Sheba Medical Center, Tel Hashomer, Israel Membership in professional and scientific societies 1. The American Association for Cancer Research; 2. The International Academy of Pathology (Norwegian division); 3. The European Society of Pathology; 4. The International Society of Gynecological Pathology; 5. Nordic Society of Gynecologic Oncology Scientific appointments 2012-: Editorial board member in Gynecologic Oncology 2011-: Associate Editor, Frontiers in Women’s Cancer 2011-: Editorial board member in Human Pathology 2010-: Editorial board member in Virchows Archiv 2010: Associate Editor, Journal of Oncology, Special issue titled Molecular Genetic Markers in Female Reproductive Cancers 2006-2013: Member of the grant application committee, Norwegian Cancer Society 2005-2012: Section Editor in Diagnostic Cytopathology Invited speaker and Reviewer - Reviewed a large number of manuscripts for leading international peer-reviewed journals, including Nature Reviews Cancer, Lancet Oncology, Cancer Research, Clinical Cancer Research, Molecular Cancer Research, Annals of Oncology, The American Journal of Pathology, Oncogene and Cancer. - Invited speaker in 26 sessions in international conferences in 2004-2014 Publications (excluding abstracts) in peer-reviewed journals: 257 per November 2014 In addition, Editor of a book on serous effusions with Springer and author of 5 chapters.

Professor Pål Møller, MD, PhD Oslo University Hospital, the Norwegian Radium Hospital, Oslo, Norway

MD, PhD, Senior Consultant, Senior Scientist.

From a background of internal medicine and a PhD on multifactorial inheritance, he was in 1988 asked to erect combined research on and health service for inherited cancer at the Norwegian Radium Hospital – currently a unit within Oslo University Hospital. He joined the international organizations developing the mathematical models to describe inherited cancer, and the inter-professional organizations describing the inherited cancer syndromes, uncover their genetic causes and advocating intervention strategies to prevent and cure. Genetic understanding is based upon genetic epidemiological facts on the inherited diseases in question, to which purpose he together with the organizations mentioned issued standardized guidelines for health care. Implementing these in the Norwegian health care system which covers all Norwegian, the system was made an open observational trial. Together with others having the same intention on providing information based on prospective observations (not only retrospective as close to all information was and still is), he became partner in broad international collaborative prospective studies. To this end he had to keep all relevant information, and in the absence of systems to do so he made his own combined electronic medical filing and research system. Today, information from the thousands of families examined the last 25 years, including results of testing for the known causative genes and effects of interventions over all these years, are available to describe the genetic epidemiology of the inherited cancers and the effects of the interventions undertaken. Because of numbers needed to arrive at conclusions, it is necessary to compile international series from different centres, for which reason the broad international collaborations are continuously ongoing. Inherited ovarian cancer is part of inherited breast-ovarian cancer caused by the BRCA1/2 genes and inherited colorectal cancer (Lynch syndrome) caused by four mismatch-repair genes. Updates from the international collaborative prospective studies on these two inherited cancers syndromes will be given.

Professor Beth Y. Karlan, MD Cedars-Sinai Medical Center, Los Angeles, CA, USA

Position title

Director, Women’s Cancer Program. Director, Gynecologic Oncology Education/training: Institution and location, degree, year(s), field of study Harvard-Radcliffe College, Cambridge, MA , B.A., 1978, Biochemistry Sciences Harvard Medical School, Cambridge, MA, M.D., 1982, Medicine Yale-New Haven Hospital, New Haven, CT, Residency, 1982-86, Obstetrics & Gynecology Yale Univ. School of Medicine, New Haven, CT, Research Fellow, 1986-87, Molecular Biology UCLA School of Medicine, Los Angeles, CA, Clinical Fellow, 1987-89, Gynecologic Oncology Personal statement As a physician and translational researcher, I have more than 30 years experience treating patients with female reproductive malignancies and investigating pressing clinical questions in the clinic and the laboratory. My research interests include the genetic and phenotypic determinants of human ovarian carcinoma, hereditary predisposition to cancer, and molecular biomarkers for early detection, treatment and prognostication of ovarian cancer. I have been awarded research grants from the Department of Defense, National Institutes of Health and the American Cancer Society. In 1989 I established a human tissue biorepository to collect and preserve fresh frozen tissue, serum, germline DNA from blood and paraffin blocks to be used for translational research studies. As of 2013, the collection contains more than 100,000 unique specimens donated by more than 10,000 patients and correlated with relevant clinical data. This robust and valuable resource has been the backbone of much of my research and will be available for the proposed projects. In addition, in 1990 I initiated the Gilda Radner Hereditary Cancer Detection Program, which enrolls women who undergo BRCA testing due to personal and/or family diagnoses. This work contributed to national ovarian cancer screening guidelines, and we are currently working with international collaborators to identify genetic modifiers of disease penetrance in carriers of deleterious BRCA gene mutations. We have also been working to identify improved biomarkers for early detection, and one of the markers identified from analysis of tumors from our bank is FDA approved and used in clinical practice for detecting recurrent ovarian cancer and triaging a pelvic mass. Throughout my career, I have devoted myself to advancing the specialty of gynecologic oncology through leadership, mentorship, and patient advocacy. I have served as president of our national and local professional societies, testified before congress in support of increased research funding and patient education, contributed to the training of many of my most respected colleagues, and currently serves as editor-in-chief of the journals Gynecologic Oncology and Gynecologic Oncology Case Reports. My ongoing efforts are inspired by the women that I treat, and dedicated to improving their lives through discovery and innovation.

Positions and Employment 1995-Present Director, Division of Gynecologic Oncology, Cedars-Sinai Medical Center, Los Angeles, CA 1998-2005 Director, Gynecologic Oncology Fellowship Program, UCLA/Cedars-Sinai Medical Centers, Los

Angeles, CA 2001-Present Professor, Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, CA 2002-2010 Director, Women’s Cancer Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 2007-Present Director, Women’s Reproductive Cancers, Center of Excellence, Cedars-Sinai Medical Center, Los

Angeles, CA 2011-Present Director, Women’s Cancer Program at the Samuel Oschin Comprehensive Cancer Institute,

Cedars-Sinai Medical Center, Los Angeles, CA Other Experience and Professional Memberships 1993 Consultant, Prostate, Lung, Colon & Ovarian Cancer Screening Trial, NCI 1997 Group Leader, Strategic Planning Conference on New Directions in Ovarian Cancer Research,

NCI 1999-2005 Board of Governors, American College of Surgeons 2000-2004 Integration Panel for the Ovarian Cancer Research Program, DOD (Chair, 2002-2003) 2000-Present Scientific and Medical Advisory Committee, Ovarian Cancer National Alliance, 2001-2008 Subspecialty Board Member (Gynecologic Oncology), American Board of Obstetrics &

Gynecology 2002-2003 President, Los Angeles Obstetrical and Gynecological Society 2004-2005 President, Western Association of Gynecologic Oncologists 2005-2006 President, Society of Gynecologic Oncologists 2006-2012 Member, Board of Directors, Cedars-Sinai Medical Center 2008-Present Editor-In-Chief, Gynecologic Oncology 2008-Present Chair, Scientific Advisory Board Clearity Foundation 2008-Present Board of Directors, Ovarian Cancer Research Fund 2011-Present Editor-In-Chief, Gynecologic Oncology Case Reports 2012-Present Member, Conquer Cancer Foundation 2013-Present Member, National Cancer Advisory Board Honors 1986 ACOG-Ortho Academic Training Fellowship in Obstetrics and Gynecology 1990 American Cancer Society Clinical Oncology Career Development Award 1992 Berlex Foundation Scholar Award 1993 Richard F. Dwyer and Eleanor W. Dwyer Award for Excellence 1995-Present Board of Governors’ Endowed Chair, Gynecologic Oncology, Cedars-Sinai Medical Center 1996 Award for Excellence, Israel Cancer Research Fund 1998 Nat King Cole Research Award, Research for Women’s Cancers, Cedars-Sinai Medical Center 2001 Gynecologic Cancer Foundation, Public Service Award 2006-2011 American Cancer Society, Early Detection Professorship 2008 Gynecologic Cancer Foundation/Margaret Greenfield/Carmel Cohen, MD, Excellence in

Ovarian Cancer Research Award 2011-2016 American Cancer Society, Clinical Research Professorship Scientific publications Karlan has published more than 230 Peer-Reviewed publications

Beth Y. Karlan, MD Cedars-Sinai Medical Center, Los Angeles, CA, USA

Professor Helga Salvesen, MD, PhD University of Bergen, Haukeland University Hospital, Bergen, Norway

Born in Oslo, Norway in 1963. Education, training and academic appointments: MD, Un. of Bergen, Norway (1989); PhD Un. of Bergen (cancer research) (2000); Visiting scholar, Un.of Chicago, USA (1998-99); Specialist in obstetrics and gynecology, Norway (EBCOG requirements) (2001); Consultant in gynecologic oncology, Haukeland Un. Hospital, Norway (2001); Professor, Un. of Bergen (2003); Visiting professor, Harvard University, Dana Farber Cancer Institute, Boston, USA (2004-05); Visiting professor, Harvard University, Broad Institute, USA (2012-13). Scientific experience: HI 25, ≈115 PubMed listed original articles. Population based tissue bank for gynecologic malignancies, Un. of Bergen (PI); International prospective multicenter trial MoMaTEC (Molecular Markers in Treatment of Endometrial Cancer (PI).

Trainees: 5 (past) and 8 (current) PhD students; 7 postdocs; 3 medical students.

Invited speaker: Harvard/DFCI (2006, 2009); Max Planck Institute, Cologne, Germany (2009); 13th Biennial Meeting International Gynecologic Cancer Society (IGCS), Prague (2010); 17th Meeting of European Society of Gynaecological Oncology (ESGO), Milan (2011); American Society of Clinical Oncology (ASCO) meeting, Chicago (2011); European Society for Medical Oncology (ESMO) meeting, Stockholm (2011).

Prizes/awards: Best presentation at the Annual meeting of Norwegian Gynecological society (1996); twice appointed best teacher, medical school (preclinical), Un. of Bergen (1997,98); Superscientists, Federation of Scandinavian Societies of Obstetrics and Gynecology (1998); Falchs juniorprice, Un. of Bergen (2003); Fulbright Foundation award for overseas studies, Harvard, Boston, USA (2004); Publication of the year, Medical Faculty, Un. of Bergen for PNAS paper (2009); Helse Vest Inovation prize (2011).

Major administrative experiences: President, Norwegian Forum for Gynecologic Oncology (2003-10); President, Norwegian Oncologic Forum (2007-08); Board member (secretary), Chairman surgery group, Nordic Society for Gynecologic Oncology (2006-10); Assistant Dean, Department of Clinical Medicine, Un. of Bergen (2005-10); Board member FriMed Norwegian Research Council (2005-09); Senior editor, International Journal of Gynecological Cancer (2008-); Council member, European Society for Gynecologic Oncology (ESGO) (2009-); Member of the Uterine task Force NCI/NIH (2010-); Disease working group, The Cancer Genome Atlas (TCGA) for Endometrial Cancer (2010-); Chair, European Network for Individualized Treatment of Endometrial Cancer (ENITEC) (2010-); Member of steering group, European Network for Translational Research in Gyneocologic Oncology (ENTRIGO) (2010-).

Patents/Licensing agreement: US 12/962,946, covered by license agreement with OvaGene.

Professor Neville Hacker, MD The University of New South Wales, Australia

Professor Neville Hacker AM graduated with First Class Honours from the University of Queensland in 1967. He trained in Obstetrics and Gynaecology at the Royal Women’s Hospital in Brisbane, and went to the University of California, Los Angeles (UCLA) to do a Fellowship in Gynaecological Oncology in 1978. After a 2 year Fellowship, he was appointed to the Faculty and in 1985, he was appointed Director of Gynaecological Oncology at UCLA. In November 1986, he returned to Australia to establish the Gynaecological Cancer Centre at the Royal Hospital for Women. He has been Director of that Centre subsequently, and is a Conjoint Professor of Gynaecological Oncology at the University of New South Wales.

Professor Hacker is a Fellow of the Royal Australian and New Zealand College of Obstetricians and Gynaecologists, a Fellow of the Royal College of Obstetricians and Gynaecologists, a Fellow of the American College of Obstetricians and Gynecologists, and a Fellow of the American College of Surgeons.

He is a past Chairman of the Oncology Committee of the RANZCOG, a Past President of the International Gynecologic Cancer Society, and a Past President of the Society of Pelvic Surgeons. He has received numerous Awards, including the 2007 Wertheim Award, the 2008 IGCS Award, the inaugural Prof Robert Sutherland Award from the NSW Cancer Institute, and the inaugural Jeanne Ferris Award from the Australian Government and Cancer Australia, both in 2013.

He has written over 180 peer-reviewed articles, 44 book chapters, and two books, Hacker and Moore’s Essentials of Obstetrics and Gynecology and Berek and Hacker’s Gynecologic Oncology, both in their 5th Edition.

Professor Nadeem R. Abu-Rustum, MD Memorial Sloan Kettering Cancer Center, New York, USA

Nadeem R. Abu-Rustum, M.D. is the Chief of the Gynecology Service in the Department of Surgery at Memorial Sloan Kettering Cancer Center in New York. He is a Professor at Weill Medical College of Cornell University in New York and is the Vice-Chair for Technology Development at Memorial Sloan Kettering Cancer Center. He completed his Residency in Obstetrics and Gynecology at the Greater Baltimore Medical Center in Baltimore Maryland and a Fellowship in Gynecologic Oncology at Memorial Sloan Kettering Cancer Center. He has authored or co-authored more than 200 publications and is co-author to numerous book chapters and three textbooks in gynecologic oncology. He is in full-time practice of gynecologic oncology at Memorial Sloan Kettering Cancer Center in New York.

Ane Gerda Zahl Eriksson, MD Memorial Sloan Kettering Cancer Center, New York, USA

Dr. Eriksson is a Gynecologic Oncology Fellow in the Department of Surgery at Memorial Sloan Kettering Cancer Center.

Dr. Eriksson earned her medical degree from the Medical University of Warsaw, graduating first in her class. As a medical student she developed an early interest in embryology and was awarded a scholarship from the Norwegian Research Council to perform research on malformations of the central nervous system at the National Center for Fetal Diagnostics. This research encouraged her to pursue a residency in Obstetrics and Gynecology. During residency her focus changed from fetal diagnostics to gynecologic oncology, and she completed the final 18 months of residency at the Norwegian Radium Hospital. Dr. Eriksson is currently pursuing specialty training in Gynecologic Oncology at MSKCC.

Dr. Eriksson has throughout her career been devoted to medical education and international collaboration. She is a founding member of the Polish chapter for the Association of Norwegian Students Abroad (ANSA), she has served as President of the Norwegian Medical Student Association, foreign division (NMF), President for the Norwegian Association of Residents in Obstetrics and Gynecology and represented the organization in the European Network of Trainees in Obstetrics and Gynecology (ENTOG). Dr. Eriksson has also served on the Board for the Norwegian Association of Obstetrics and Gynecology.

Her current research centers on minimally invasive surgery in gynecologic oncology and the utilization of sentinel lymph node mapping for uterine cancers. She plans on pursuing an academic career in Gynecologic Oncology upon completion of her fellowship.

Professor Frédéric Amant, MD, PhD UZ Gasthuisberg/KU Leuven, Belgium

Frédéric Amant, MD, PhD (°1967), received his medical degree from the University of Leuven (KU Leuven), Belgium in 1992, completed his specialty training as an obstetrician/gynecologist in 1998, and his subspecialty training in gynecologic oncology in 2000. He is professor at the KU Leuven, Belgium. He is a specialist in Gynecologic Oncology at the University Hospitals (UZ Gasthuisberg) Leuven and heads the scientific section of this specialty.

Frédéric Amant heads the International Network on ‘Cancer, Infertility and Pregnancy’ (INCIP) of the European Society of Gynecologic Oncology (ESGO) (www.cancerinpregnancy.org).

He chairs the Endometrium Tumor Site Committee of the European Organization for Research and Treatment of Cancer (EORTC), Gynecologic Cancer Group. He is co-chair of the European Network Individualized Treatment Endometrial Cancer (ENITEC), a task force within the ESGO. He chairs the patient derived tumour xenograft platform (PDTX) at the KU Leuven and is member of the European consortium on xenografts.

Olesya Solheim, MD, PhD fellow Oslo University Hospital, the Norwegian Radium Hospital, Oslo, Norway

MD, PhD fellow at the Department of Gynecological Oncology, the Norwegian Radium Hospital.

Olesya Solheim has her medical education from the State Medical Academy of Arkhangelsk, Russia, 1999. After receiving her degree as medical doctor she underwent 4 years of specialization within obstetrics and gynecology from the same institution.

Dr Solheim moved to Norway in 2003 and received authorization of her medical education from Russia as professionally equivalent to the degree Candidate of Medicine of the University of Oslo (Candidata Medicinae - Cand. Med.). Having settled in Oslo she has been working at different departments of Oslo University hospital. In the period 2006-2007, she was trained in internal medicine at Lillehammer hospital, and was in 2007 authorized as medical doctor by the Norwegian governmental office for authorization of health personnel.

Since 2008 she has been working at the Oslo University Hospital, Dep. Of Gynecological Oncology, the Norwegian Radium Hospital.

From March 2012 Olesya Solheim has been engaged as PhD fellow in the project "Long-term outcome in survivors after Germ Cell Ovarian Cancer". This project is the first national study of Germ Cell ovarian tumors and is conducted in cooperation between the Departments of gynecological oncology in Oslo, Trondheim, Bergen, Tromsø and the National Resource Center for Studies after Treatment for Cancer OUS, the Norwegian Radium Hospital.

Publications:

Malignant ovarian germ cell tumors: presentation, survival and second cancer in a population based Norwegian cohort (1953-2009). Solheim O, Kærn J, Tropé CG, Rokkones E, Dahl AA, Nesland JM, Fosså SD. Gynecol Oncol. 2013 Nov;131(2):330-5.

Prognostic factors in malignant ovarian germ cell tumours (The Surveillance, Epidemiology and End Results experience 1978-2010). Solheim O, Gershenson DM, Tropé CG, Rokkones E, Sun CC, Weedon-Fekjaer H, Fosså SD. Eur J Cancer. 2014 Jul;50(11):1942-50.

Professor Gunnar B Kristensen, MD, PhD Oslo University Hospital, the Norwegian Radium Hospital, Oslo, Norway

Born 1946 in Denmark

Medical degree 1972

Specialist in Gynecology and Obstetrics 1972

Senior physician in Oncology 1982

Senior physician in Obstetrics and Gynecology, Denmark 1983-89

Consultant in Gynecologic Oncology, The Norwegian Radium Hospital since 1990

1999 Thesis, Oslo, Norway.

2013 Appointed as professor in Gynecology and Obstetrics at University in Oslo.

President for Nordic Society for Gynecologic Oncology (NSGO) 1999-2006

Director of NSGO-CTU (Clinical Trial Unit) 2006-2013

Authorship of 225 scientific articles published in international, peer-reviewed journals.

Author of chapters in 20 books.

List of participants

Last name First name Affiliation Country

Abeler Vera The Norwegian Radium Hospital Norway Abu-Rustum Nadeem Memorial Sloan Kettering Cancer Center, New York USA Ahlgren Madelaine Karlskrona Hospital Sweden Ahuja Vijay K. Women’s Hospital, Doha Qatar Amant Frédéric UZ Gasthuisberg/KU Leuven Belgium Anderssen Elena University Hospital of North Norway Norway Andersson Yvonne The Norwegian Radium Hospital Norway Arildsen Nicolai Skovbjerg Lund University Sweden Auranen Annika Turku University Hospital Finland Bäckman Fatma Örebro University Hospital Sweden Bangshöj Rene Örebro University Hospital Sweden Berle Einar Oslo Medical Center Norway Bischof Katharina Haukeland University Hospital Norway Bjørge Line Haukeland University Hospital Norway Bjørn Signe Frahm Rigshospitalet, Copenhagen Denmark Blaakær Jan Aarhus University Hospital Denmark Bondhus Sissel Roche Norge Norway Bossmar Thomas University of Lund Sweden Chrisanthar Ranjan The Norwegian Radium Hospital Norway Dahl Gunn Fallås The Norwegian Radium Hospital Norway Davidson Ben The Norwegian Radium Hospital Norway Dørum Anne The Norwegian Radium Hospital Norway Elgaaen Bente Vilming The Norwegian Radium Hospital Norway Eroukhmanoff Lena NCMM, University of Oslo Norway Eraker Runar Akershus University Hospital Norway Eriksson Ane Gerda Zahl Memorial Sloan Kettering Cancer Center, New York USA Eyjolfsdottir Brynhildur The Norwegian Radium Hospital Norway Fiane Bent Stavanger University Hospital Norway Flaten Kristine Drammen Hospital Norway Frøding Ligita P Rigshospitalet, Copenhagen Denmark Hacker Neville The University of New South Wales Australia Hagen Bjørn St. Olavs Hospital Norway Hamid Bushra Hassan Roskilde Hospital Denmark Hansen Lars Jul Sørlandet Hospital Arendal Norway Heggheim Arne Stavanger University Hospital Norway Huang Ruixia The Norwegian Radium Hospital Norway Hynninen Johanna Turku University Hospital Finland Høgdall Claus Juliane Marie Centret, Rigshospitalet Denmark Høgdall Estrid VS Herlev Hospital Denmark

Last name First name Affiliation Country

Hølmebakk Toto The Norwegian Radium Hospital Norway Iversen Ole Erik Haukeland University Hospital Norway J:son- Söderström

Annelie Karlskrona Hospital Sweden

Jeppesen Ulla Region Hospital of Randers Denmark Jochumsen Kirsten Marie Odense University Hospital Denmark Jönsson Jenny-Maria Skane University Hospital, Lund Sweden Kaiander Christin Roche Norge Norway Karlan Beth Cedars-Sinai Medical Center, Los Angeles USA Ketabi Zohreh Odense University Hospital Denmark Kildal Wanja The Norwegian Radium Hospital Norway Klynning Charlotte Karolinska Hospital Sweden Komulainen Marja Kuopio University Hospital Finland Kraggerud Sigrid Marie The Norwegian Radium Hospital Norway Kristensen Gunnar The Norwegian Radium Hospital Norway Kristoff Anne Stavanger University Hospital Norway Kærn Janne The Norwegian Radium Hospital Norway Langmark Frøydis Oslo Norway Larsen Stein The Norwegian Radium Hospital Norway Li Xiaoran The Norwegian Radium Hospital Norway Lindström Annika Centrum för Klinisk Forskning Dalarna Sweden Lorenz Elke Tønsberg Medical Center Norway Lunde Kristian Roche Norge Norway Mengistu Meseret Kvinnohälsan Söder, Stockholm Sweden Micci Francesca The Norwegian Radium Hospital Norway Mikic Marinko Sørlandet Hospital Arendal Norway Møller Pål The Norwegian Radium Hospital Norway Nesland Jahn M The Norwegian Radium Hospital Norway Nilsen Elisabeth Berge Stavanger University Hospital Norway Noorda Thomas Østfold Hospital, Fredrikstad Norway Oksefjell Halldis Ålesund Norway Othman Suher North Zealand Hospital Denmark Ottosen Christian Juliane Marie Centret, Rigshospitalet Denmark Persson Jan Skane University Hospital, Lund Sweden Pradhan Manohar The Norwegian Radium Hospital Norway Rasmussen Hege Lund The Norwegian Radium Hospital Norway Riemersma Cecilia Karlstad Sweden Rintala Marjut Turku University Hospital Finland Rokkones Erik The Norwegian Radium Hospital Norway Rokne Jan Anders Vestfold Hospital Norway Roos Aviaja Siegstad Roskilde Hospital Denmark

Last name First name Affiliation Country

Sachse Kurt Akershus University Hospital Norway Sahlin Anna Kvinnokliniken Eskilstuna Sweden Saleem Zeyad Halmstad Hospital Sweden Sallinen Hanna Kaisa Kuopio University Hospital Finland Salvesen Helga Haukeland University Hospital Norway Schnack Tine Henrichsen Roskilde Hospital Denmark Schultz Janine Radium Hospital Foundation Norway Schulze-Stahl Niels Kvinnoklinken Västerås Sweden Seppola Gry The Norwegian Radium Hospital Norway Sert Bilal The Norwegian Radium Hospital Norway Skeie-Jensen Tone The Norwegian Radium Hospital Norway Skirnisdottir Ingiridur Akademiska Hospital, Uppsala Sweden Skogsfjord Karin The Norwegian Radium Hospital Norway Skrøppa Siri Vestfold Hospital Norway Sletten Elise University Hospital of North Norway Norway Smebye Marianne Lislerud The Norwegian Radium Hospital Norway Smehaug Ola Roche Norge Norway Smogeli Elisabeth The Norwegian Radium Hospital Norway Solbakken Ingunn The Norwegian Radium Hospital Norway Solheim Olesya The Norwegian Radium Hospital Norway Steen Rita The Norwegian Radium Hospital Norway Steffensen Karina Dahl Vejle Hospital Denmark Stensager Per Arne The Norwegian Radium Hospital Norway Sundfeldt Karin Sahlgrenska Cancer Centre Sweden Sundfør Kolbein The Norwegian Radium Hospital Norway Szczesny Witold Innlandet Hospital Norway Søgaard Charlotte H Aalborg University Hospital Denmark Thranov Ingrid Rigshospitalet, Copenhagen Denmark Tropé Ameli The Norwegian Radium Hospital Norway Tropé Claes The Norwegian Radium Hospital Norway Tveten Kim Ada Sobi Norway Vistad Ingvild Sørlandet Hospital Norway Waldstrøm Marianne Vejle Hospital Denmark Wang Yun The Norwegian Radium Hospital Norway Wang Yun Yong The Norwegian Radium Hospital Norway Warsla Gry Vestre Viken Hospital Trust Norway Woie Kathrine Haukeland University Hospital Norway Zhong Yali The Norwegian Radium Hospital Norway Ørtoft Gitte Aarhus University Hospital Denmark

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