Embed Size (px)
DESCRIPTION
good
Citation preview
US 20140256687A1
(19) United States (12) Patent Application Publication (10) Pub. No.: US 2014/0256687 A1
Tamura et al. (43) Pub. Date: Sep. 11, 2014
(54)
(75)
(73)
(21)
(22)
(86)
(30)
Jun. 29, 2011
AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPOSITION AND METHOD FOR USING THE SAME
Inventors: Shingo Tamura, Tokyo (JP); Takao Aoki, Osaka (JP); Ken Kuriyama, Tokyo (JP)
Assignee: NIHON NOHYAKU CO., LTD., Tokyo (JP)
Appl. No.: 14/125,508
PCT Filed: Jun. 28, 2012
PCT No.:
§ 371 (0X1)’ (2), (4) Date:
PCT/JP2012/066474
Feb. 14, 2014
Foreign Application Priority Data
(JP) ............................... .. 2011444379
(51)
(52)
(57)
Publication Classi?cation
Int. Cl. A01N57/14 (2006.01) A01N57/12 (2006.01) A01N 41/10 (2006.01) U.S. Cl. CPC .............. .. A01N57/14 (2013.01); A01N41/10
(2013.01); A01N57/12 (2013.01) USPC ........................................................ .. 514/136
ABSTRACT
Provided are an agricultural and horticultural insecticide composition comprising ?ubendiamide and dichlorvos and/ or profenofos as active ingredients; and a method for using an agricultural and horticultural insecticide composition, com prising treating insect pests directly, treating crops potentially infested With the insect pests, or treating surrounding soil or cultivation medium of the crops With an effective amount of an agricultural and horticultural insecticide composition comprising ?ubendiamide and dichlorvos and/ or profenofos as active ingredients.
US 2014/0256687 A1
AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPOSITION AND METHOD FOR USING THE SAME
TECHNICAL FIELD
[0001] The present invention relates to an agricultural and horticultural insecticide composition comprising ?ubendia mide and dichlorvos and/ or profenofos as active ingredients; and a method for using the same.
BACKGROUND ART
[0002] Flubendiamide is a commercially available com pound as an agricultural and horticultural insecticide. It is known that various combinations of ?ubendiamide or its rela tive compound and an agricultural and horticultural insecti cide have a complementary effect on the insecticidal spec trum and that speci?c combinations of them produce a synergistic effect (for example, see Patent Literature 1 to 5 and Non Patent Literature 1). Dichlorvos and profenofos are also commercially available compounds as agricultural and horticultural insecticides (for example, see Patent Literature 6 and 7 and Non Patent Literature 1). However, compositions comprising a combination of ?ubendiamide and dichlorvos and/ or profenofos are not known, and it is not known at all that the insecticidal effect of such a composition is synergistically greater than that of each compound used separately.
CITATION LIST
Patent Literature
[0003] Patent Literature 1: JP-A 2001 -131 141 [0004] Patent Literature 2: WO 2002/087334 [0005] Patent Literature 3: WO 2004/034786 [0006] Patent Literature 4: WO 2005/004603 [0007] Patent Literature 5: WO 2005/004604 [0008] Patent Literature 6: US. Pat. No. 2,956,073 [0009] Patent Literature 7: GB Patent No. 1417116
Non Patent Literature
[0010] Non Patent Literature 1: [0011] The Pesticide Manual 14th Edition (British Crop
Production Council)
SUMMARY OF INVENTION
Technical Problem
[0012] In the production of agricultural produce, the dam age caused by various insect pests is still large and treatment with various insecticides is required for control of the insect pests. Such insecticide treatment imposes a particularly great burden on farmers, and reducing the treatment operation has been strongly desired in terms of occupational health, in particular the reduction of farmers’ workload, as well as in terms of economics, in particular the reduction of production costs of agricultural produce. To this end, various kinds of agricultural and horticultural insecticide compositions have been developed. However, in conventional art, effective pest control cannot be achieved in some cases because of the kind of insect pest to be controlled, habitat characteristics, devel opment of insecticide resistance, etc. Under such circum
Sep. 11,2014
stances, the development of novel technologies for ef?ciently controlling insect pests that have been dif?cult or impossible to control is desired.
Solution to Problem
[0013] The present inventors conducted extensive research to solve the above-described problems. As a result, the present inventors found that a combined use of ?ubendiamide (general name) (chemical name: 3-iodo-W-(2-mesyl-1,1 dimethylethyl) -N- {4 -[1 ,2, 2, 2-tetra?uoro -1 -(tri?uorom ethyl)ethyl]-o-tolyl}phthalamide), known as an agricultural and horticultural insecticide, and dichlorvos (general name) (chemical name: 2,2-dichlorovinyl dimethyl phosphate) and/ or profenofos (general name) (chemical name: O-4-bromo 2-chlorophenyl O-ethyl S-propyl phosphorothioate), simi larly each known as an agricultural and horticultural insecticide, has advantages over a separate use of each com pound, such as remarkable synergistic effect, expansion of the range of target insect pests, dose reduction, reduction of treatment frequency, etc. Thus, the present invention was completed. [0014] That is, the present invention relates to the follow ing. [1] An agricultural and horticultural insecticide composition comprising ?ubendiamide and dichlorvos and/ or profenofos as active ingredients.
[2] The agricultural and horticultural insecticide composition according to the above [1], comprising 0.1 to 10 parts by mass of dichlorvos and/or profenofos per part by mass of ?uben diamide.
[3] A method for using an agricultural and horticultural insec ticide composition, comprising treating insect pests directly, treating crops potentially infested with the insect pests, or treating surrounding soil or cultivation medium of the crops with an effective amount of an agricultural and horticultural insecticide composition comprising ?ubendiamide and dichlorvos and/or profenofos as active ingredients.
[4] A method for controlling agricultural and horticultural insect pests, comprising treating insect pests directly, treating crops potentially infested with the insect pests, or treating surrounding soil or cultivation medium of the crops with an effective amount of an optionally diluted formulation con taining ?ubendiamide as an active ingredient and an effective amount of an optionally diluted formulation containing dichlorvos and/or profenofos as an active ingredient(s), the two formulations being used separately but in the same period. [5] A method for controlling agricultural and horticultural insect pests, comprising treating insect pests directly, treating crops potentially infested with the insect pests, or treating surrounding soil or cultivation medium of the crops with an effective amount of an optionally diluted formulation con taining ?ubendiamide as an active ingredient and an effective amount of an optionally diluted formulation containing dichlorvos and/or profenofos as an active ingredient(s), the two formulations being used separately at a given interval.
[6] A method for controlling agricultural and horticultural insect pests, comprising mixing an effective amount of a formulation containing ?ubendiamide as an active ingredient and an effective amount of a formulation containing dichlo rvos and/or profenofos as an active ingredient(s); optionally diluting the mixture; and treating insect pests directly, treat
US 2014/0256687 A1
ing crops potentially infested with the insect pests, or treating surrounding soil or cultivation medium of the crops with the optionally diluted mixture.
Advantageous Effects of Invention
[0015] The present invention relates to an agricultural and horticultural insecticide composition comprising ?ubendia mide and dichlorvos and/ or profenofos as active ingredients; and a method for using the same. The agricultural and horti cultural insecticide composition and the method have advan tages over a separate use of each compound, such as remark able synergistic effect, expansion of the range of target insect pests, dose reduction, reduction of treatment frequency, etc. Therefore, the present invention provides a novel technology for ef?ciently controlling insect pests that have been impos sible or dif?cult to control by conventional technologies.
DESCRIPTION OF EMBODIMENTS
[0016] Flubendiamide, which is one of the active ingredi ents of the agricultural and horticultural insecticide compo sition of the present invention, can be produced according to the production method disclosed in Patent Literature 1 etc., but commercial formulations thereof are also available for purchase. The other active ingredient(s), dichlorvos (also called DDVP) and profenofos, can be produced according to the production method disclosed in Patent Literature 6 and 7, but commercial formulations thereof are also available for purchase. These compounds, an appropriate inactive carrier and a surfactant, and if needed an adjuvant are blended in an appropriate ratio, and through the step of dissolution, sepa ration, suspension, mixing, impregnation, adsorption and/or adhesion, are formulated into an appropriate form for appli cation, such as a suspension concentrate (?owable), an emul si?able suspension concentrate, an emulsi?able concentrate, a soluble concentrate, a wettable powder, a water-dispersible granule, a granule, a dust, a microcapsule, a capsule, a tablet, ajumbo and a pack. [0017] The total content of the active ingredients in the agricultural and horticultural insecticide composition of the present invention can be adjusted as needed without particu lar limitation, but is usually about 0.01 to 90 parts by mass. For example, in the case where the agricultural and horticul tural insecticide composition is a dust or a granule, the total content of the active ingredients is preferably about 0.1 to 30 parts by mass, and in the case where the agricultural and horticultural insecticide composition is an emulsi?able con centrate, a wettable powder, a ?owable, a water-dispersible granule or the like, the total content of the active ingredients is preferably about 0.1 to 60 parts by mass. The blending ratio of the active ingredients ?ubendiamide and dichlorvos and/ or profenofos in the agricultural and horticultural insecticide composition of the present invention is appropriately selected from the range of 0.1 to 10 parts by mass of dichlorvos and/or profenofos per part by mass of ?ubendiamide. [0018] As for these active ingredients, their commercial formulations may be used as they are. Alternatively, the active ingredients can be prepared into separate formulations or a combined formulation. For the preparation of a formulation, the active ingredient(s) and an appropriate inactive carrier, and if needed an adjuvant are blended in an appropriate ratio, and through the step of dissolution, separation, suspension, mixing, impregnation, adsorption and/or adhesion, are for mulated into an appropriate form for application, such as a
Sep. 11,2014
suspension concentrate (?owable), an emulsi?able suspen sion concentrate, an emulsi?able concentrate, a soluble con centrate, a wettable powder, a water-dispersible granule, a granule, a dust, a microcapsule, a capsule, a tablet, a jumbo and a pack.
[0019] The inactive carrier may be a solid or liquid carrier. Examples of the solid carrier include natural minerals, such as quartz, clay, kaolinite (kaolin), pyrophyllite, sericite, talc, bentonite, acid clay, attapulgite, zeolite and diatomite; inor ganic salts, such as calcium carbonate, ammonium sulfate, sodium sulfate and potassium chloride; organic solid carriers, such as synthetic silicic acid, synthetic silicates, starch, cel lulose and plant powders (for example, sawdust, coconut shell, corn cob, tobacco stalk, etc.); plastics carriers, such as polyethylene, polypropylene and polyvinylidene chloride; urea; hollow inorganic materials; hollow plastic materials; and fumed silica (white carbon). These solid carriers may be used alone or in a combination of two or more kinds.
[0020] Examples of the liquid carrier include alcohols including monohydric alcohols, such as methanol, ethanol, propanol, isopropanol and butanol, and polyhydric alcohols, such as ethylene glycol, diethylene glycol, propylene glycol, hexylene glycol, polyethylene glycol, polypropylene glycol and glycerin; polyol compounds, such as propylene glycol ether; ketones, such as acetone, methyl ethyl ketone, methyl isobutyl ketone, diisobutyl ketone and cyclohexanone; ethers, such as ethyl ether, dioxane, ethylene glycol monoethyl ether, dipropyl ether and tetrahydrofuran; aliphatic hydrocarbons, such as normal paraf?n, naphthene, isoparaf?n, kerosene and mineral oil; aromatic hydrocarbons, such as benzene, tolu ene, xylene, solvent naphtha and alkyl naphthalene; haloge nated hydrocarbons, such as dichloromethane, chloroform and carbon tetrachloride; esters, such as ethyl acetate, diiso propyl phthalate, dibutyl phthalate, dioctyl phthalate and dimethyl adipate; lactones, such as gamma-butyrolactone; amides, such as dimethylformamide, diethylformamide, dim ethylacetamide and N-alkyl pyrrolidone (N-methylpyrroli done etc.); nitriles, such as acetonitrile; sulfur compounds, such as dimethyl sulfoxide; vegetable oils, such as soybean oil, rapeseed oil, cotton seed oil and castor oil; and water. These liquid carriers may be used alone or in a combination of two or more kinds.
[0021] Examples of the adjuvant include surfactants used as a dispersant, a wetting agent, a spreader, a sticking/spread ing agent, etc., binders, tacki?ers, thickeners, colorants, anti freeZing agents, anti-caking agents, disintegrants and stabi liZing agents. If needed, preservatives, plant fragments, etc. may be additionally used. These adjuvants may be used alone or in a combination of two or more kinds.
[0022] Examples of the surfactants used as a dispersant, a wetting agent, a spreader, a sticking/spreading agent, etc. include nonionic surfactants, such as sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, sucrose fatty acid ester, polyoxyethylene fatty acid ester, polyoxyethylene resin acid ester, polyoxyethylene fatty acid diester, polyoxyethyl ene alkyl ether, polyoxyethylene alkyl aryl ether, polyoxyeth ylene alkyl phenyl ether, polyoxyethylene dialkyl phenyl ether, polyoxyethylene alkyl phenyl ether-formaldehyde con densates, polyoxyethylene-polyoxypropylene block copoly mers, polystyrene-polyoxyethylene block polymers, alkyl polyoxyethylene-polypropylene block copolymer ether, polyoxyethylene alkylamine, polyoxyethylene fatty acid amide, polyoxyethylene fatty acid bis(phenyl ether), poly alkylene benzyl phenyl ether, polyoxyalkylene styryl phenyl
US 2014/0256687 A1
ether, acetylene diol, polyoxyalkylene-added acetylene diol, polyoxyethylene ether-type silicone, ester-type silicone, ?uorosurfactants, polyoxyethylene castor oil and polyoxy ethylene hydrogenated castor oil; anionic surfactants, such as alkyl sulfates, polyoxyethylene alkyl ether sulfates, polyoxyethylene alkyl phenyl ether sul fates, polyoxyethylene styryl phenyl ether sulfates, alkylben zene sulfonates, alkylaryl sulfonates, lignosulfonates, alkyl sulfosuccinates, naphthalene sulfonates, alkylnaphthalene sulfonates, salts of naphthalenesulfonic acid-formaldehyde condensates, salts of alkylnaphthalenesulfonic acid-formal dehyde condensates, fatty acid salts, polycarboxylic acid salts, polyacrylates, N-methyl-fatty acid sarcosinates, resinates, polyoxyethylene alkyl ether phosphates and poly oxyethylene alkyl phenyl ether phosphates; cationic surfactants including alkyl amine salts, such as lauryl amine hydrochloride, stearyl amine hydrochloride, oleyl amine hydrochloride, stearyl amine acetate, stearyl amino propyl amine acetate, alkyl trimethyl ammonium chloride and alkyl dimethyl benzalkonium chloride; and amphoteric surfactants, such as amino acid-type or betaine-type ampho teric surfactants. These surfactants may be used alone or in a combination of two or more kinds.
[0023] Examples of the binders or the tacki?ers include carboxymethyl cellulose and salts thereof, dextrin, soluble starch, xanthan gum, guar gum, sucrose, polyvinyl pyrroli done, gum arabic, polyvinyl alcohol, polyvinyl acetate, sodium polyacrylate, polyethylene glycols with an average molecular weight of 6,000 to 20,000, polyethylene oxides with an average molecular weight of 100,000 to 5,000,000, phospholipids (for example, cephalin, lecithin, etc.), cellu lose powder, dextrin, modi?ed starch, polyaminocarboxylic acid chelating compounds, cross-linked polyvinyl pyrroli done, maleic acid-styrene copolymers, (meth)acrylic acid copolymers, half esters of polyhydric alcohol polymer and dicarboxylic anhydride, water soluble polystyrene sul fonates, para?in, terpene, polyamide resins, polyacrylates, polyoxyethylene, waxes, polyvinyl alkyl ether, alkylphenol formaldehyde condensates and synthetic resin emulsions. [0024] Examples of the thickeners include water soluble polymers, such as xanthan gum, guar gum, diutan gum, car boxymethyl cellulose, polyvinyl pyrrolidone, carboxyvinyl polymers, acrylic polymers, starch derivatives and polysac charides; and inorganic ?ne powders, such as high grade bentonite and fumed silica (white carbon). [0025] Examples of the colorants include inorganic pig ments, such as iron oxide, titanium oxide and prussian blue; and organic dyes, such as alizarin dyes, azo dyes and metal phthalocyanine dyes. [0026] Examples of the antifreeZing agents include poly hydric alcohols, such as ethylene glycol, diethylene glycol, propylene glycol and glycerin. [0027] Examples of the adjuvants serving to prevent caking or facilitate disintegration include polysaccharides (starch, alginic acid, mannose, galactose, etc.), polyvinyl pyrroli done, fumed silica (white carbon), ester gum, petroleum resin, sodium tripolyphosphate, sodium hexametaphosphate, metal stearates, cellulose powder, dextrin, methacrylate copolymers, polyvinyl pyrrolidone, polyaminocarboxylic acid chelating compounds, sulfonated styrene-isobutylene maleic anhydride copolymers and starch-polyacrylonitrile graft copolymers. [0028] Examples of the stabiliZing agents include desic cants, such as zeolite, quicklime and magnesium oxide; anti
Sep. 11,2014
oxidants, such as phenolic compounds, amine compounds, sulfur compounds and phosphoric acid compounds; and ultraviolet absorbers, such as salicylic acid compounds and benzophenone compounds. Examples of the preservatives include potassium sorbate and 1,2-benzothiazolin-3-one. [0029] Further, other adjuvants including functional spreading agents, activity enhancers such as metabolic inhibi tors (piperonyl butoxide etc.), antioxidants (BHT etc.) and ultraviolet absorbers can also be used if needed.
[0030] The “crops” for which the agricultural and horticul tural insecticide composition of the present invention can be used is not particularly limited, and the examples include cereals such as rice, barley, wheat, rye, oats, corn and sor ghum; legumes such as soybeans, azuki beans, broad beans, green peas and peanuts; fruit trees and fruits such as apples, mandarin oranges, oranges, lemons, limes, grapefruits, Chi nese quinces, quinces, pears, European pears, Japanese pears, grapes, blueberries, cranberries, blackberries, raspberries, strawberries, peaches, Japanese plums, nectarines, Japanese apricots, cherries, apricots, prunes, walnuts, hazelnuts, almonds, pistachio nuts, cashew nuts, macadamia nuts, bananas, persimmons, olives, loquats, date palms, coconut palms and oil palms; vegetables such as cabbages, tomatoes, spinach, broccoli, lettuce, onions, welsh onions, green pep pers, eggplants, kohlrabi, Chinese cabbages, leaf mustard, cauli?ower, garland chrysanthemum, artichoke, asparagus, carrots, parsley, celery, parsnips and chard; root vegetables such as carrots, burdock roots, potatoes, sweet potatoes, J apa nese yam, taro, Japanese radishes, lotus roots and tumips; crops for processing such as cotton, hemp, paper mulberry, oriental paperbush, rapeseeds, oil palms, Barbados nuts, buckwheat, beet, hops, sugarcane, sugar beet, olives, rubber, coffee, tobacco, mulberry and tea; gourd such as Japanese pumpkins, cucumbers, zucchini, waterrnelons and melons; pasture grass such as orchard grass, sorghum, timothy, clover and alfalfa; lawn grass such as Japanese lawn grass, Korean lawn grass, Bermuda grass, redtop, creeping bentgrass, colonial bent grass, Kentucky bluegrass, rough bluegrass, tall fescue, chewings fescue, creeping red fescue, annual ryegrass, peren nial ryegrass, orchard grass and timothy grass; spice and aromatic crops such as lavender, rosemary, thyme, parsley, pepper, red pepper, Japanese horseradish, ginger, garlic, shiso, mint and basil; ?oweringplants such as rose, carnation, chrysanthemum, lisianthus, baby’s breath, sun?ower, ger bera, marigold, salvia, petunia, verbena, tulip, aster, gentian, lily, pansy, cyclamen, orchid, lily of the valley, lavender, stock, omamental kale, primula, poinsettia, gladiolus, catt leya, daisy, verbena, cymbidium and begonia; and trees such as Japanese ash, birch, ?owering dogwood, eucalyptus, ginkgo, lilac, maple, live oak, poplar, Chinese redbud, Chi nese sweet gum, plane, Japanese zelkova, Japanese T huja, Momi ?r, southern Japanese hemlock, temple juniper, pine, spruce, Japanese yew, elm, buckeye, sweet Viburnum, Bud dhist pine, Japanese cedar, Japanese cypress, croton, Japa nese spindle and Japanese phalinia. [0031] The “crops” include crops provided with a useful trait by a classical breeding technique and a recently advanced gene recombination technique, for example, genetically modi?ed crops (e.g., herbicide-tolerant crops, insect pest-resistant transgenic crops producing insecticidal proteins, disease-resistant transgenic crops producing induc ers of disease resistance, palatability-enhanced crops, long term preservable crops, high-yield crops, etc.).
US 2014/0256687 A1
[0032] Exemplary crops provided with herbicide tolerance by a classical breeding technique include varieties of rape seed, wheat, sun?ower, rice and corn tolerant to the imida zolinone family of ALS-inhibiting herbicides such as imazethapyr, and such crops are sold under the trade name of Clear?eld (registered trademark). Also included is a variety of soybean provided with tolerance to the sulfonyl urea fam ily of ALS-inhibiting herbicides such as thifensulfuron-me thyl by a classical breeding technique, and this is sold under the trade name of STS soybean. Also included are crops provided with tolerance to acetyl-CoA carboxylase inhibitors such as trione oxime herbicides and aryloxy phenoxy propi onic acid herbicides by a classical breeding technique, for example, SR corn and the like.
[0033] Exemplary crops provided with herbicide tolerance by a gene recombination technique include glyphosate-toler ant varieties of corn, soybean, cotton, rapeseed and sugarbeet, and such crops are sold under the trade names such as Roundup Ready (registered trademark) and Agrisure GT. Also included are varieties of corn, soybean, cotton and rape seed genetically engineered to be tolerant to glufosinate, and such crops are sold under the trade name of LibertyLink (registered trademark) etc.Also included is a variety of cotton genetically engineered to be tolerant to bromoxynil, and this is sold under the trade name of BXN.
[0034] Crops provided with tolerance to acetyl-CoA car boxylase inhibitors are described in Proc. Natl. Acad. Sci. USA, 87, 7175-7179 (1990), and the like. Further, acetyl CoA carboxylase mutants resistant to acetyl-CoA carboxy lase inhibitors are reported in Weed Science, 53, 728-746 (2005), and the like, and by introducing the gene of such an acetyl-CoA carboxylase mutant into crops by a gene recom bination technique, or introducing a resistance-conferring mutation into acetyl-CoA carboxylase of crops, crops toler ant to acetyl-CoA carboxylase inhibitors can be engineered. Alternatively, by introducing a nucleic acid causing base substitution mutation into crop plant cells (a typical example of this technique is chimeraplasty technique (Gura T. 1999. Repairing the Genome’s Spelling Mistakes. Science 285: 316-318.)) to allow site-speci?c substitution mutation in the amino acids encoded by an acetyl-CoA carboxylase gene of crops, crops tolerant to acetyl-CoA carboxylase inhibitors can be engineered.
[0035] The “crops” also include crops genetically engi neered to synthesize insecticidal toxins etc. Exemplary insec ticidal toxins expressed in such genetically modi?ed crops include insecticidal proteins derived from Bacillus cereus or Bacillus papilliae; Bacillus Zhuringiensis-derived delta-en dotoxins, such as CrylAb, CrylAc, CrylF, CrylFa2, Cry2Ab, Cry3A, Cry3Bb1 and Cry9C, and other insecticidal proteins, such as VlPl, VlP2, VlP3 and VlP3A; nematode derived insecticidal proteins; toxins produced by animals, such as scorpion toxins, spider toxins, bee toxins and insect speci?c neurotoxins; toxins of ?lamentous fungi; plant lec tins; agglutinin; protease inhibitors, such as trypsin inhibi tors, serine protease inhibitors, patatin, cystatin and papain inhibitors; ribosome inactivating proteins (RIP), such as ricin, maize RIP, abrin, saporin and bryodin; steroid metabolizing enzymes, such as 3-hydroxy steroid oxidase, ecdysteroid UDP-glucosyltransferase and cholesterol oxidase; ecdysone inhibitors; HMG-CoA reductase; ion channel inhibitors, such as sodium channel inhibitors and calcium channel inhibitors; juvenile hormone esterase; diuretic hormone receptors; stil bene synthase; bibenzyl synthase; chitinase; and glucanase.
Sep. 11,2014
Examples of the foregoing toxins and genetically modi?ed crops capable of synthesizing these toxins are described in EP-A-0374753, WO 93/07278, WO 95/34656, EP-A 0427529, EP-A-451878, WO 03/052073, etc. The toxins con tained in such genetically modi?ed crops are suitable for control of pests, in particular, Coleopteran insect pests, Dipteran insect pests and Lepidopteran insect pests, and due to the toxins, the crops exhibit resistance to such pests. [0036] Genetically modi?ed crops which express one or more of the insecticidal toxins are already known, and some of them are commercially available. Examples of such geneti cally modi?ed crops include YieldGard (registered trade mark), which is a variety of corn expressing a CrylAb toxin; YieldGard Rootworm (registered trademark), which is a vari ety of corn expressing a Cry3Bb1 toxin; YieldGard Plus (reg istered trademark), which is a variety of corn expressing CrylAb and Cry3Bb1 toxins; Herculex I (registered trade mark), which is a variety of corn expressing a CrylFa2 toxin and phosphinothricin N-acetyltransferase (PAT) for tolerance to glufosinate; NuCOTN33B (registered trademark) and Bollgardl (registered trademark), which are varieties of cot ton expressing a Cry1Ac toxin; Bollgard 11 (registered trade mark), which is a variety of cotton expressing Cry1Ac and Cry2Ab toxins; VIPCOT (registered trademark), which is a variety of cotton expressing aVlP toxin; NewLeaf (registered trademark), which is a variety of potato expressing a Cry3A toxin; NatureGard (registered trademark) Agrisure (regis tered trademark) GT Advantage (a GA21 glyphosate-tolerant trait), Agrisure (registered trademark) CB Advantage (a Bt11 corn borer (CB) trait); and Protecta (registered trademark). [0037] Further, the “crops” also include crops genetically engineered to produce selectively acting anti-pathogenic sub stances. Examples of the anti-pathogenic substances include PR proteins (PRPs; described in EP-A-03 92225); ion channel inhibitors, such as sodium channel inhibitors and calcium channel inhibitors (for example, KPl, KP4 and KP6 toxins, which are produced in viruses, are known); stilbene synthase; bibenzyl synthase; chitinase; glucanase; and substances pro duced by microbes, such as peptide antibiotics, heterocyclic antibiotics and plant disease resistance-related protein factors (referred to as plant disease resistance genes and described in WO 03/000906). Examples of the foregoing anti-pathogenic substances and genetically modi?ed crops capable of produc ing these substances are described in EP-A-0392225, WO 95/33818, EP-A-0353191, etc. [0038] Further, the “crops” also include crops provided with a useful trait such as an improved proportion of oil components and a higher amino acid content by a gene recombination technique. Examples of such crops include VlSTlVE (registered trademark), which is a variety of soy bean engineered to have a reduced linolenic acid content, and high-lysine (or high-oil) corn, which is a variety of corn engineered to have an increased content of lysine or oil.
[0039] Furthermore, the “crops” also include stacked vari eties with a combination of two or more selected from the above-described classical herbicide-tolerant traits, herbicide tolerant genes, insecticidal pest-resistance genes, anti-patho genic substance-producing genes and useful traits including an improved proportion of oil components and a higher amino acid content. When the agricultural and horticultural insecti cide composition of the present invention is used for crops modi?ed to be tolerant to a herbicide, systematic and/or mixed treatment with the herbicide (for example, glyphosate or its salts, glufosinate or its salts, dicamba or its salts,
US 2014/0256687 A1
imazethapyr or its salts, isoxa?utole, etc.) and the agricultural and horticultural insecticide composition of the present invention can control weeds and insect pests in an integrated manner.
[0040] In the use of the agricultural and horticultural insec ticide composition of the present invention, the above-de scribed formulation(s) containing an active ingredient(s) is/are optionally diluted or suspended in water etc., and insect pests are directly treated with, or target crops potentially infested with the insect pests, seeds of the target crops, soil or cultivation medium for planting the seeds, or the like are treated with the optionally diluted or suspended formulation (s) in an amount (s) effective for insect pest control according to a usual method. Examples of the treatment method include spray treatment of foliage etc., treatment of nursery boxes for paddy rice, seed treatment such as dust coating, dipping and disinfection of seeds, planting hole treatment, plant foot treat ment, planting row treatment, drench treatment and soil incorporation treatment. Also included is treatment of water culture media in hydroponics. [0041] The seed treatment may be performed in a usual manner. The exemplary methods include dipping of seeds in a diluted or undiluted ?uid of a liquid or solid formulation for the permeation of agrochemicals into the seeds; mixing, dust coating or other treatment of seeds with a liquid or solid formulation for the adherence of agrochemicals onto the sur faces of the seeds; monolayer or multilayer coating of seeds with a mixture of a liquid or solid formulation and a highly adhesive carrier such as resins and polymers; and application of a liquid or solid formulation to the vicinity of seeds at the same time as seeding. The term “seed” used in the seed treatment is, in a broad sense, synonymous with a plant body used for propagation. The examples include, in addition to a so-called seed, a plant body for vegetative propagation, such as a bulb, a tuber, a seed potato, a discoid stem and a stem used for cuttage. [0042] In the method of the present invention, the term “soil” or “cultivation medium” refers to support medium for plant cultivation and the materials are not particularly limited as long as plants can grow. Examples of the support medium include so-called soils of various kinds, seedling mats and water, and also include sand, vermiculite, cotton, paper, diatomite, agar, gelatinous substances, high-molecular weight substances, rock wool, glass wool, wood chip, bark and pumice. [0043] Exemplary methods of soil application include application of a water-diluted or undiluted liquid or solid formulation to the vicinity of planting points, nursery beds for seedlings, or the like; application of a granule to the vicinity of planting points or nursery beds; application of a dust, a wettable powder, a water-dispersible granule, a granule or the like onto soil and subsequent incorporation of the formulation into the whole soil before seeding or transplanting; and appli cation of a dust, a wettable powder, a water-dispersible gran ule, a granule or the like to planting holes, planting rows or the like before seeding or planting. [0044] To nursery boxes for paddy rice, for example, a dust, a water-dispersible granule, a granule or the like can be applied, although the suitable formulation may vary depend ing on the application time, in other words, depending on the cultivation stage such as seeding time, greening period and planting time. In the soil application, a formulation such as a dust, a water-dispersible granule, a granule or the like may be mixed with soil. For example, such a formulation is incorpo
Sep. 11,2014
rated into bed soil, covering soil or the whole soil. Simply, soil and such a formulation may be alternately layered. In the application at the seeding time, the timing of the application may be before, at the same time as, or after seeding, or after covering with soil. In the case of paddy rice, submerged application of a granule etc. to a paddy ?eld is often per formed. [0045] For ?eld crops, such as potato, sweet potato and soybean, preferred is treatment of their seeds, cultivation media in the vicinity of plants, or the like in the period of seeding to seedling culture. For plants of which the seeds are directly sown in the ?eld, in addition to direct seed treatment, treatment of cultivation media in the vicinity of plants or the like during cultivation is preferable. Speci?cally, the treat ment can be performed by, for example, applying a granule onto soil, or drenching soil with a formulation in a water diluted or undiluted liquid form. [0046] In the case of culture plants to be transplanted, examples of the treatment in the period of seeding to seedling culture include, in addition to direct seed treatment, drench treatment of nursery beds for seedlings with a formulation in a liquid form; and granule application to nursery beds for seedlings. Also included are treatment of planting holes with a granule; and incorporation of a granule into cultivation media in the vicinity of planting points at the time of ?x planting. [0047] For the above-described treatment, a ?ubendiamide single formulation and a dichlorvos or profenofos single for mulation can be used after mixed with each other on site, and such a use can also produce the desired insecticidal effect. Alternatively, for the above-described treatment, the two single formulations canbe separately used in the same period, and such a use can also produce the desired insecticidal effect. The term “the same period” does not mean that treatments with the two single formulations are performed at the exact same time, and in the case where treatments with the two single formulations are performed within a time frame of about one week, the treatments can be regarded as being performed “in the same period.” Further, each treatment can be performed by a different method. Alternatively, for the above-described treatment, the two single formulations can be separately used at a given interval, and such a use can also produce the desired insecticidal effect. The interval between the treatments is not particularly limited as long as the effect of the present invention can be exerted, but in general, the interval is preferably 3 months or less, and particularly pref erably 2 months or less. In this case, the ?rst treatment may be performed with any of the active ingredients and each treat ment may be performed by a different method. [0048] In recent years, IPM (integrated pest management) technology using insect sex pheromones (e.g., communica tion disrupting agents against Tortricidae and Hadeninae, etc.), natural enemy insects, etc. has made progress, and this technology and the composition of the present invention can be used in combination or used systematically.
[0049] The amount of the agricultural and horticultural insecticide composition used for treatment may vary with various factors, for example, the purpose, the target insect pest, the crop growing conditions, the weather, the environ mental conditions, the formulation, the application method, the application site, the application time, etc., but for example, the amounts of the active ingredient compounds are as follows: in the case of spray treatment, 1 to 200 g/ha of ?ubendiamide and 100 to 2000 g/ha of dichlorvos and/or
US 2014/0256687 A1
profenofos are applied to target crops; and in the case of soil treatment or drench treatment, 1 to 100 g/ ha of ?ubendiamide and 50 to 1000 g/ha of dichlorvos and/ or profenofos are applied onto or in?ltrated into the surrounding soil of target crops.
[0050] The agricultural and horticultural insecticide com position of the present invention is suitable for controlling a variety of insect pests Which may damage paddy rice, veg etables, fruits, other ?owering plants, etc. The insect pests to be controlled are, for example, agricultural and forest pests, horticultural pests, stored grain pests, sanitary pests, nema todes, etc. The speci?c examples include the following: species of the Order Lepidoptera such as Parasa consocia, Anomis mesogona, Papilio xuthus, Matsumuraeses azukivora, Ostrinia scapulalis, Spodoptera exempta, Hyphantria cunea, Ostrinia furnacalis, Pseudaletia sepa rata, Til’lELl translucens, Bactra furfurana, Parnara guttata, Marasmia exigua, Parnara guttata, Sesamia inferens, Broch mia triannulella, Monema?avescens, Trichoplusia ni, Pleu roptya ruralis, Cystidia couaggaria, Lampides boeticus, Cephonodes hylas, Helicoverpa armigera, Phalerodonta manleyi, Eumeta japonica, Pieris brassicae, Malacosoma neustria testacea,
Stathmopoda masinissa, Cuphodes diospyrosella, Archips xylosteanus, Agrotis segetum, Tetramoera schistaceana, Papilio machaon hippocrates, Endoclyta sinensis, Lyonetia prunifoliella, Phyllonorycter ringoneella, Cydia kurokoi, Eucoenogenes aestuosa, Lobesia botrana, Latoia sinica, Euzophera batangensis, Phalonidia mesotypa, Spilosoma imparilis, Glyphodespyloalis, Olethreutes mori, Hneola bis selliella, Endoclyta excrescens, Nemapogon granellus, Synanthedon hector, Cydia pomonella, Plutella xylostella, Cnaphalocrocis medinalis, Sesamia calamistis, Scirpophaga incertulas, Pediasia teter rellus, Phthorimaea operculella, Stauropus fagi persimilis, Etiella Zinckenella, Spodoptera exigua, Palpifer sexnotata, Spodoptera manuritia, Scirpophaga innotata, Xestia c-ni grum, Spodoptera depravata, Ephestia kuehniella, Angerona prunaria, Clostera anastomosis, Pseudoplusia includens, Matsumuraeses falcana, Helicoverpa assulta, Autographa nigrisigna, Agrotis ipsilon, Euproctis pseudoconspersa, Adoxophyes orana, Caloptilia theivora, Homona magn anima, Ephestia elutella, Eumeta minuscula, Clostera anachoreta, Heliothis maritima, Sparganothispilleriana, Busseolafusca, Euproctis sub?ava, Biston robustum, Heliothis zea, Aedia leucomelas, Narosoideus?avidorsalis, Vlminia rumicis, Buc culatrix pyrivorella, Grapholita molesta, Spulerina astau rota, Ectomyelois pyrivorella, Chilo suppressalis, Acrolepi opsis sapporensis, Plodia interpunctella, Hellula undalis, Sitotroga ceralella, Spodoptera litura, a species of the family Tortricidae (Eucosma aporema), Acleris comariana, Scopelodes contracus, Orgyia thyellina, Spodoptera fru giperda, Ostrinia zaguliaevi, Naranga aenescens, Andraca bipunctata, Paranthrene regal is, Acosmeryx castanea, Phyllocnistis toparcha, Endopiza viteana, Eupoecillia ambiguella, Anticarsia gemmatalis, Cnephasia cinereipal pana, Lymantria dispar, Dendrolimus spectabilis, Legumini vora glycinivorella, Maruca testulalis, Matsumuraeses phaseoli, Caloptilia soyella, Phyllocnistis citrella, Hadylepta indicata, Archips fuscocupreanus, Acanthoplusia agnata, Bambalina sp., Carposina niponensis, Conogethes punc tiferalis, Synanthedon sp., Lyonetia clerkella,
Sep. 11,2014
Papilio helenus, Colias erate poliographus, Phalera ?ave scens, species of the family Pieridae such as Pieris rapae, Euproctis similis, Acrolepiopsis suzukiella, Ostrinia nubila lis, Mamestra brassicae, Ascotis selenaria, Phtheochroides clandestina, Hoshinoa adumbratana, Odonestisprunijapon ensis, T riaena intermedia, Adoxophyes oranafasciata, Gra pholita inopinata, Spilonota ocellana, Spilonota lechriaspis, Illiberispruni, Argyresthia conjugella, Caloptilia zachrysa, Archips breviplicanus, Anomis ?ava, Pectinophora gossyp iella, Notarcha derogata, Diaphania indica, Heliothis vire scens and Earias cupreoviridis;
species of the Order Hemiptera such as Nezara antennata, Stenotus rubrovittatus, Graphosoma rubrolineatum, Trigo notylus coelestialium, Aeschynteles maculatus, Creontiades pallidifer, Dysdercus cingulatus, Chrysomphalus ?cus, Aonidiella aurantii, Graptopsaltria nigrofuscata, Blissus leucopterus, Iceryapurchasi, Piezodorus hybneri, Lagynoto mus elongatus, T haia subrufa, Scotinophara lurida, Sitobion ibarae, Stariodes iwasakii, Aspidiotus destructor, Taylorily gus pallidulus, Myzus mumecola, Pseudaulacaspis pruni cola, Acyrthosiphon pisum, Anacanthocoris striicornis, Ectometopterus micantulus, Eysarcoris lewisi, Molipteryx fulginosa, Cicadella viridis, Rhopalosophum ru?abdominalis, Saissetia oleae, T rialeurodes vaporari orum, A guriahana quercus, Lygus sp., Euceraphispunctipen nis, Andaspis kashicola, Coccus pseudomagnoliarum, Cav elerius saccharivorus, Galeatus spinifrons, Macrosiphoniella sanborni, Aonidiella citrina, Halyomor pha mista, Stephanitisfasciicarina, T rioza camphorae, Lep tocorisa chinensis, T rioza quercicola, Uhlerites latius, Eryth roneura comes, Paromius exguus, Duplaspidiotus claviger, Nephotettix nigropictus, Halticiellus insularis, Perkinsiella saccharicida, Psylla malivorella, Anomomeura mori, Pseudococcus longispinis, Pseudaula caspis pentagona, Pulvinaria kuwacola, Apolygus lucorum, Togo hemipterus, Toxoptera aurantii, Saccharicoccus sac chari, Geoica lucifuga, Numata muiri, Comstockaspisperni ciosa, Unaspis citri, Aulacorthum solani, Eysarcoris ventra lis, Bemisia argentifolii, Cicadella spectra, Aspidiotus hederae, Liorhyssus hyalinus, Calophya nigridorsalis, Soga tellafurcifera, Megoura crassicauda, Brevicoryne brassicae, Aphis glycines, Leptocorisa oratorius, Nephotettix virescens, Uroeuconformosanum, Cyrtopeltis tennuis, Bemisia tabaci, Lecanium persicae, Parlatoria theae, Pseudaonidia paeo niae, Empoasca onukii, Plautia stali, Dysaphis tulipae, Mac rosiphum euphorbiae, Stephanitis pyrioides, Ceroplastes ceriferus, Parlatoria camelliae, Apolygus spinolai, Nephotet tix cincticeps, Glaucias subpunctatus, Orthotylus?avospar sus, Rhopalosiphum maidis, Peregrinus maidis, Eysarcoris parvus, Cimex lectularius, Psylla abieti, Nilaparvata lugens, Psylla tobirae, Eurydema rugosum, Schizophis piricola, Psylla pyricola, Parlatoreopsis pyri, Stephanitis sashi, Dys micoccus wistariae, Lepholeucaspis japonica, Sappaphis piri, Lipaphis erysimi, Neotoxopteraformosana, Rhopaloso phum nymphaeae, Edwardsiana rosae, Pinnaspis aspidis trae, Psylla alni, Speusotettix subfusculus, Alnetoidia alneti, Sogatella panicicola, Adelphocoris lineolatus, Dysdercus poecilus, Parlatoria Ziziphi, Uhlerites debile, Laodelphax striatellus, Eurydemapulchrum, Cletus trigonus, Clovia punctata, Empoasca sp., Coccus hesperidum, Pachybrachius luridus, Planococcus kraunhiae, Stenotus binotatus, Arbo ridia apicaris, Macrostelesfasci?’ons, Dolycoris baccarum, Adelphocoris triannulatus, Vlteus vitifolii, Acanthocoris sor didus, Leptocorisa acuta,
US 2014/0256687 A1
Macropes obnubilus, Cletus puncliger, Riplorlus clavalus, Paralrioza cockerelli, Aphrophora coslalis, Lygus disponsi, Lygus saundersi, Crisicoccus pini, Empoasca abielis, Crisi coccus malsumoloi, Aphis craccivora, Megacopla punclalis simum, Eysarcoris gulliger, Lepidosaphes beckii, Diaphorina cilri, Toxoplera cilricidus, Planococcus cilri, Dialeurodes cilri, Aleurocanlhus spiniferus, Pseudococcus cilriculus, Zyginella cilri, Pulvinaria cilricola, Coccus discrepans, Pseudaonidia duplex, Pulvinaria auranlii, Lecanium corni, Nezara viridula, Slenodema calcaralum, Rhopalosiphum padi, Silobion akebiae, Schizaphis graminum, Sorhoanus Zrilici, Brachycaudus heli chrysi, Carpocoris purpureipennis, Myzus persicae, Hya lopleruspruni, Aphis farinoseyanagicola, Melasalispopuli, Unaspis yanonensis, Mesohomoloma camphorae, Aphis spi raecola, Aphis pomi, Lepidosaphes ulmi, Psylla mali, Hel erocordylus?avipes, Myzus malisuclus, Aphidonuguis mali, Orienlus ishidai, Ovalus malicolens, Eriosoma lanigerum, Ceroplasles rubens and Aphis gossypii; species of the Order Coleoptera such as Xyslrocera globosa, Paederusfuscipes, Eucelonia roelofsi, Callosobruchus chin ensis, Cylas formicarius, Hypera poslica, Echinocnemus squameus, Oulema oryzae, Donacia provosli, Lissorhoplrus oryzophilus, Colasposoma dauricum, Euscepes poslfascia Zus, Epilachna variveslis, Acanlhoscelides obleclus, Diabrolica virgifera virgifera, Involvulus cupreus, Aula cophorafemoralis, Bruchuspisorum, Epilachna viginlioclo maculala, Carpophilus dimidialus, Cassida nebulosa, Luperomorpha Zunebrosa, Phyllolrela slriolala, Psacolhea hilaris, Aeoleslhes chrysolhrix, Curculio sikkimensis, Carpophilus hemiplerus, Oxycelonia jucunda, Diabrolica sp., Mimela splendens, Silophilus zea mais, T ribolium caslaneum, Silophilus oryzae, Palorus sub depressus, Melolonlha japonica, Anoplophora malasiaca, Nealus picipes, Leplinolarsa decemlineala, Diabrolica undecimpunclala howardi, Sphenophorus venalus, Crioceris qualuordecimpunclala, Conolrachelus nenuphar, Ceulho rhynchidius albosuluralis, Phaedon brassicae, Lasioderma serricorne, Silonajaponicus, Adorelus Zenuimaculalus, Tene brio m0li20r, Basilepla balyi, Hypera nigriroslris, Chaeloc nema concinna, Anomala cuprea, Heplophylla picea, Epil achna viginlioclopunclala, Diabrolica longicornis, Eucelonia pilifera, Agrioles spp., Allagenus unicolorjaponicus, Pagria signala, Anomala rufo cuprea, Palorus ralzeburgii, Alphilobius laevigalus, Anthre nus verbasci, Lyclus brunneus, T ribolium confusum, Medylhia nigrobilineala, Xylolrechus pyrrhoderus, Epilrix cucumeris, Tomicus piniperda, Monochamus allernalus, Popillia japonica, Epicaula gorhami, Silophilus zeamais, Rhynchiles heros, Lislroderes cosliroslris, Callosobruchus maculalus, Phyllobius armalus, Anthonomus pomorum, Linaeidea aenea and Anthonomus grandis; species of the Order Diptera such as Culex pipiens pallens, Pegomya hyoscyami, Liriomyza huidobrensis, Musca domes Zica, Chlorops oryzae, Hydrellia sasakii, Agromyza oryzae, Hydrellia griseola, Ophiomyia phaseoli, Dacus cucurbilae, Drosophila suzukii, Rhacochlaenajaponica, Muscina slabu lans, species of the family Phoridae such as Megaselia spi racularis, Clogmia albipunclala, lipula aino, Phormia regina, Culex Zrilaeniorhynchus, Anopheles sinensis, Hyl emya brassicae, Asphondylia sp., Delia plalura, Delia anti qua, Rhagolelis cerasi, Culexpipiens m0leslus Forskal, Cer alilis capilala, Bradysia agreslis, Pegomya cunicularia, Liriomyza salivae, Liriomyza bryoniae, Chromalomyia hor
Sep. 11,2014
Zicola, Liriomyza chinensis, Culex quinquefascialus, Aedes aegypli, Aedes albopiclus, Liriomyza Zrifolii, Dacus dorsal is, Dacus Zsuneonis, Silodiplosis m0sellana, Meromuza nigrivenlris, Anaslrepha ludens and Phagolelis pomonella; species of the Order Hymenoptera such as Prislomyrmex pungens, species of the family Bethylidae, Monomorium pharaosis, Pheidole noda, Alhalia rosae, Dryocosmus kuriphilus, Formica fusca japonica, species of the subfamily Vespinae, Alhalia infumala infumala, Arge pagana, Alhalia japonica, Acromyrmex spp., Solenopsis spp., Arge mali and Ochelellus glaber; species of the Order Orthoptera such as Homorocoryphus lineosus, Gryllolalpa sp., Oxya hyla inlricala, Oxya yezoen sis, Locusla migratoria, Oxya japonica, Homorocoryphus jezoensis and Teleogryllus emma; species of the Order Thysanoptera such as Selenolhrips rubrocinclus, Slenchaelolhrips biformis, Haplolhrips aculealus, Ponliculolhrips diospyrosi, Thrips?avus, Anapho Zhrips obscurus, Liolhrips?oridensis, T hrips simplex, T hrips nigropilosus, Heliolhrips haemorrhoidalis, Pseudodendro Zhrips m0ri, Microcephalolhrips abdominalis, Leeuwenia pasanii, Lilolelolhrips pasaniae, Scirlolhrips cilri, Haplo Zhrips chinensis, Myclerolhrips glycines, Thrips selosus, Scir Zolhrips dorsalis, Dendrolhrips minowai, Haplolhrips niger, Thrips Zabaci, Thrips alliorum, Thrips hawaiiensis, Haplo Zhrips kurdjumovi, Chirolhrips manicalus, Frankliniella inlonsa, T hrips coloralus, Franklinella occidentalis, T hrips palmi, Frankliniella lilivora and Liolhrips vaneeckei; species of the Order Acari such as Leplolrombidium aka mushi, Telranychus ludeni, Dermacenlor variabilis, Telrany chus Zruncalus, Ornithonyssus bacoli, Demodex canis, Tel ranychus viennensis, Telranychus kanzawai, species of the family lxodidae such as Rhipicephalus sanguineus, Cheyl eZus malaccensis, Drophagus pulrescenliae, Dermalopha goidesfarinae, Lalrodeclus hassellii, Dermacenlor Zaiwani cus, Acaphylla Zheavagrans, Polyphagolarsonemus lalus, Aculops lycopersici, Ornithonyssus sylvairum, Telranychus urticae, Eriophyes chibaensis, Sacroples scabiei, Haema physalis longicornis, Ixodes scapularis, Drophagus similis, Cheylelus erudilus, Panonychus cilri, Cheylelus m00rei, Brevipalpus phoenicis, Oclodecles cynolis, Dermalopha goides plrenyssnus, Haemaphysalis ?ava, Ixodes ovalus, Phyllocoplrula cilri, Aculus schlechlendali, Panonychus ulmi, Amblyomma americanum and Dermanyssus gallinae; species of the Order lsoptera such as Reliculilermes miyalakei, Incisilermes minor, Coplolermes formosanus, Hodolermopsis japonica, Reliculilermes sp., Reliculilermes ?aviceps amamianus, Glyplolermes kushimensis, Coploler mes guangzhoensis, Neolermes koshunensis, Glyplolermes kodamai, Glyplolermes salsumensis, Cryptolermes domesti cus, Odonlolermes formosanus, Glyplolermes nakajimai, Pericaprilermes nilobei and Reliculilermes speralus; species of the Order Blattodea such as Periplanelafuliginosa, Blallella germanica, Blalla orientalis, Periplanela brunnea, Blallella liluricollis, Periplanela japonica and Periplanela americana; species of the Order Siphonaptera such as Pulex irritans, Clenocephalidesfelis and Ceralophyllus gallinae; species of the Phylum Nematoda such as Nolholylenchus acris, Aphelenchoides besseyi, Pralylenchus penetrans, Meloidogyne hapla, Meloidogyne incognila, Globodera ros Zochiensis, Meloidogyne javanica, Helerodera glycines, Pralylenchus cofeae, Pralylenchus negleclus and Hlenchus semipenelrans; and
US 2014/0256687 A1
species of the Phylum Mollusca such as Pomacea canalicu lala, Achalinafulica, Meghimalium bilinealum, Lehmannina valenliana, Limacus?avus andAcusZa despecla sieboldiana. Other agricultural and horticultural insect pests to be con trolled are, for example, Tula absolula and the like. [0051] The agricultural and horticultural insecticide com position of the present invention can be used simultaneously With agricultural and horticultural microbicides, agricultural and horticultural insecticides, agricultural and horticultural herbicides, synergists, phytotoxicity reducers, etc. for control of diseases/insect pests, weeds, etc. Which may spread in the application period of the composition of the present inven tion, enhanced effects and reduced phytotoxicity to crops. Non-limiting examples of typical compounds used as the agricultural and horticultural microbicides, the agricultural and horticultural insecticides, the agricultural and horticul tural herbicides, the synergists or the phytotoxicity reducers are listed beloW.
[0052] Examples of the agricultural and horticultural microbicides include aureofungin, azaconazole, aZithiram, acypetacs, acibenzolar, acibenzolar-S-methyl, azoxystrobin, anilaZine, amisulbrom, ampropylfos, ametoctradin, allyl alcohol, aldimorph, amobam, isotianil, isovaledione, isopy razam, isofetamid, isoprothiolane, ipconazole, iprodione, iprovalicarb, iprobenfos, imazalil, iminoctadine, iminocta dine-albesilate, iminoctadine-triacetate, imibenconazole, uniconazole, uniconazole-P, echlomezole, edifenphos, eta conazole, ethaboxam, ethirimol, etem, ethoxyquin, etridiaZ ole, enestroburin, epoxiconazole, oxadixyl, oxycarboxin, copper-8-quinolinolate, oxytetracycline, copper-oxinate, oxpoconazole, oxpoconazole-fumarate, oxolinic acid, octhilinone, ofurace, orysastrobin, metam-sodium, kasugamycin, carbamorph, carpropamid, carbendaZim, car boxin, carvone, quinazamid, quinacetol, quinoxyfen, chi nomethionat, quinomethionate, captafol, captan, kiralaxyl, quinconazole, quintozene, guazatine, cufraneb, cuprobam, glyodin, griseofulvin, climbazole, cresol, kresoxim-methyl, chlozolinate, clotrimazole, chlobenthiazone, chlorani formethan, chloranil, chlorquinox, chloropicrin, chloroneb, salicylanilide, zarilamid, cyazofamid, diethyl pyrocarbonate, diethofencarb, cyclafuramid, diclocymet, dichlozoline, diclobutrazol, dichlo?uanid, cycloheximide, diclomeZine, dicloran, dichlorophen, dichlone, disulfuram, ditalimfos, dithianon, diniconazole, diniconazole-M, Zineb, dinocap, dinocton, dinosulfon, dinot erbon, dinobuton, dinopenton, dipyrithione, diphenylamine, difenoconazole, cy?ufenamid, di?umetorim, cyproconazole, cyprodinil, cyprofuram, cypendazole, simeconazole, dime thirimol, dimethomorph, cymoxanil, dimoxystrobin, methyl bromide, Ziram, silthiofam, streptomycin, spiroxamine, sul tropen, sedaxane, zoxamide, dazomet, thiadiaZin, tiadinil, thiadi?uor, thiabendazole, tioxymid, thioquinox, thiochlor fenphim, thiophanate, thiophanate-methyl, thicyofen, thi ?uzamide, thiram, decafentin, tecnazene, tecloftalam, teco ram, tetraconazole, debacarb, dehydroacetic acid, tebuconazole, tebu?oquin, dodicin, dodine, dodecyl benzensulfonate bis-ethylene diamine copper(ll) (DBEDC), dodemorph, drazoxolon, triadimenol, triadime fon, triaZbutil, triazoxide, triamiphos, triarimol, trichlamide, tricyclazole, triticonazole, tridemorph, tributyltin oxide, tri ?umizole, tri?oxystrobin, triforine, tolyl?uanid, tolclofos methyl, tolprocarb, natamycin, nabam, nitrostyrene, nitrothal-isopropyl, nuarimol, copper nonylphenol sulfonate, halacrinate, validamycin, valifenalate, harpin protein, bix
Sep. 11,2014
afen, picoxystrobin, picobenzamide, bithionol, bitertanol, hydroxyisoxazole, hydroxyisoxazole-potassium, binapacryl, biphenyl, piperalin, hymexazol, pyraoxystrobin, pyracar bolid, pyraclostrobin, pyrazophos, pyrametostrobin, pyri ofenone, pyridinitril, pyrifenox, pyribencarb, pyrimethanil, pyroxychlor, pyroxyfur, pyro quilon, Vinclozolin, ferbam, famoxadone, fenapanil, fenami done, fenaminosulf, fenarimol, fenitropan, fenoxanil, ferim zone, fentin, fenpiclonil, fenpyrazamine, fenbuconazole, fenfuram, fenpropidin, fenpropimorph, fenhexamid, phtha lide, buthiobate, butylamine, bupirimate, fuberidazole, blas ticidin-S, furametpyr, furalaxyl, ?uacrypyrim, ?uaZinam, ?u oxastrobin, ?uotrimazole, ?uopicolide, ?uopyram, ?uoroimide, furcarbanil, ?uxapyroxad, ?uquinconazole, fur conazole, furconazole-cis, ?udioxonil, ?usilazole, ?usulfa mide, ?utianil, ?utolanil, ?utriafol, furfural, furrnecyclox, ?umetover, ?umorph, proquinaZid, prochloraZ, procymi done, prothiocarb, prothioconazole, propamocarb, propiconazole, propineb, furophanate, probenazole, bromuconazole, hexachlorobuta diene, hexaconazole, hexylthiofos, bethovain, benalaxyl, benalaxyl-M, benodanil, benomyl, pefurazoate, benquinox, penconazole, benzamorf, pencycuron, benzohydroxamic acid, bentaluron, benthiazole, benthiavalicarb, benthiavali carb-isopropyl, penthiopyrad, pen?ufen, boscalid, phos diphen, fosetyl, fosetyl-Al, polyoxins, polyoxorim, polycar bamate, folpet, formaldehyde, machine oil, maneb, mancozeb, mandipropamid, myclozolin, myclobutanil, mil diomycin, milneb, mecarbinZid, methasulfocarb, metazoxo lon, metam, metam-sodium, metalaxyl, metalaxyl-M, meti ram, methyl isothiocyanate, meptyldinocap, metconazole, metsulfovax, methfuroxam, metominostrobin, metrafenone, mepanipyrim, mefenoxam, meptyldinocap, mepronil, mebe nil, iodomethane, rabenzazole, benzalkonium chloride, inor ganic microbicides such as basic copper chloride, basic cop per sulfate and silver, sodium hypochlorite, cupric hydroxide, wettable sulfur, calcium polysul?de, potassium hydrogen carbonate, sodium hydrogen carbonate, sulfur, copper sulfate anhydride, nickel dimethyldithiocarbamate, oxine copper, Zinc sulfate and copper sulfate pentahydrate. [0053] Examples of the agricultural and horticultural insec ticides include 3,5-xylyl methylcarbamate (XMC), crystal line protein toxins produced by Bacillus Zhuringiensis such as Bacillus Zhuringiensis aizawai, Bacillus Zhuringiensis israe lensis, Bacillus Zhuringiensis japonensis, Bacillus Zhuring iensis kurslaki and Bacillus Zhuringiensis Zenebrionis, BPMC, Bt toxin-derived insecticidal compounds, CPCBS (chlorfenson), DCIP (dichlorodiisopropyl ether), D-D (1,3 dichloropropene), DDT, NAC, O-4-dimethylsulfamoylphe nyl 0,0-diethyl phosphorothioate (DSP), O-ethyl O-4-nitro phenyl phenylphosphonothioate (EPN), tripropylisocyanurate (TPIC), acrinathrin, azadirachtin, aZin phos-methyl, acequinocyl, acetamiprid, acetoprole, aceph ate, abamectin, a?dopyropen, avermectin-B, amido?umet, amitraZ, alanycarb, aldicarb, aldoxycarb, aldrin, alpha-en dosulfan, alpha-cypermethrin, albendazole, allethrin, isazo fos, isoamidofos, isoxathion, isofenphos, isoprocarb (MIPC), ivermectin, imicyafos, imidacloprid, imiprothrin, indoxac arb, esfenvalerate, ethiofencarb, ethion, ethiprole, etoxazole, ethofenprox, ethoprophos, etrimfos, emamectin, emamectin benzoate, endosulfan, empenthrin, oxamyl, oxydemeton-me thyl, oxydeprofos (ESP), oxibendazole, oxfendazole, potas sium oleate, sodium oleate, cadusafos, cartap, carbaryl, carbosulfan, carbofuran, gamma-cyhalothrin, xylylcarb,
US 2014/0256687 A1
quinalphos, kinoprene, chinomethionat, cloethocarb, clothianidin, clofenteZine, chromafenozide, chlorantranilip role, chlorethoxyfos, chlordimeform, chlordane, chlorpyri fos, chlorpyrifos-methyl, chlorphenapyr, chlorfenson, chlor fenvinphos, chlor?uazuron, chlorobenZilate, chlorobenzoate, kelthane (dicofol), salithion, cyanophos (CYAP), diafenthi uron, diamidafos, cyantraniliprole, theta-cypermethrin, dienochlor, cyenopyrafen, dioxabenzofos, diofenolan, sigma-cypermethrin, dichlofenthion (ECP), cycloprothrin, disulfoton, dinotefuran, cyhalothrin, cyphenothrin, cy?uthrin, di?ubenzuron, cy?umetofen, di?ovidaZin, cyhexatin, cypermethrin, dimethylvinphos, dimethoate, dime?uthrin, sila?uofen, cyromaZine, spinetoram, spinosad, spirodiclofen, spirotetramat, spiromesifen, sul?uramid, sul profos, sulfoxa?or, zeta-cypermethrin, diaZinon, tau-?uvalinate, dazomet, thiacloprid, thiamethoxam, thiodi carb, thiocyclam, thiosultap, thiosultap-sodium, thionaZin, thiometon, deet, dieldrin, tetrachlorvinphos, tetradifon, tet ramethyl?uthrin, tetramethrin, tebupirimfos, tebufenozide, tebufenpyrad, te?uthrin, te?ubenzuron, demeton-S-methyl, temephos, deltamethrin, terbufos, tralopyril, tralomethrin, trans?uthrin, triazamate, triazuron, trichlamide, trichlorphon (DEP), tri?umuron, tolfenpyrad, naled (BRP), nithiaZine, nitenpyram, novaluron, novi?umuron, hydroprene, vanilip role, vamidothion, parathion, parathion-methyl, halfenprox, halofenoZide, bistri?uoron, bisultap, hydramethylnon, hydroxy propyl starch, binapacryl, bifenazate, bifenthrin, py?ubumide, pymetroZine, pyraclofos, pyra?uprole, pyridafenthion, pyridaben, pyridalyl, pyri?uquinazon, pyriprole, pyriproxy fen, pirimicarb, pyrimidifen, pirimiphos-methyl, pyrethrins, ?pronil, fenazaquin, fenamiphos, phenisobromolate, feni trothion (MEP), fenoxycarb, fenothiocarb, phenothrin, fenobucarb, fensulfothion, fenthion (MPP), phenthoate (PAP), fenvalerate, fenpyroximate, fenpropathrin, fenbenda zole, butathiofos, buproerin, furathiocarb, prallethrin, ?u acrypyrim, ?uaZinam, ?uazuron, ?uensulfone, ?ucycloxuron, ?ucythrinate, ?uvalinate, ?upyradifurone, ?upyrazofos, ?u?prole, ?ufenerim, ?ufenoxuron, ?ufenZine, ?ufenprox, ?uproxyfen, ?ubro cythrinate, ?umethrin, ?urimfen, prothiofos, protrifenbute, ?onicamid, propaphos, propargite (BPPS), pro?uthrin, pro poxur (PHC), ?ometoquin, bromopropylate, beta-cy?uthrin, hexa?umuron, hexythiazox, heptenophos, permethrin, ben clothiaZ, bendiocarb, bensultap, benzoximate, benfuracarb, phoxim, phosalone, fosthiazate, fosthietan, phosphamidon, phosphocarb, phosmet (PMP), polynactins, formetanate, for mothion, phorate, machine oil, malathion, milbemycin, milbemycin-A, milbemectin, mecar ham, mesulfenfos, methomyl, metaldehyde, meta?umizone, methamidophos, metam-ammonium, metam-sodium, methiocarb, methidathion (DMTP), methylisothiocyanate, methylneodecanamide, methylparathion, metoxadiazone, methoxychlor, methoxyfenozide, meto?uthrin, methoprene, metolcarb, meper?uthrin, mevinphos, monocrotophos, monosultap, lambda-cyhalothrin, ryanodine, lufenuron, res methrin, lepimectin, rotenone, levamisole hydrochloride, fenbutatin oxide, morantel tartarate, methyl bromide, tricy clohexyltin hydroxide (cyhexatin), calcium cyanamide, cal cium polysul?de, sulfur and nicotine-sulfate. [0054] Examples of the agricultural and horticultural her bicides include 1-naphthylacetamide, 2,4-PA, 2,3,6-TBA, 2,4,5-T, 2,4,5-TB, 2,4-D, 2,4-DB, 2,4-DEB, 2,4-DEP, 3,4 DA, 3,4-DB, 3,4-DP, 4-CPA (4-chlorophenoxyacetic acid),
Sep. 11,2014
4-CPB, 4-CPP, MCP, MCPA, MCPA-thioethyl, MCPB, ioxy nil, aclonifen, azafenidin, aci?uorfen, aZiprotryne, aZimsul furon, asulam, acetochlor, atraZine, atraton, anisuron, anilo fos, aviglycine, abscisic acid, amicarbazone, amidosulfuron, amitrole, aminocyclopyrachlor, aminopyralid, amibuZin, amiprophos-methyl, ametridione, ametryn, alachlor, alli dochlor, alloxydim, alorac, iofensulfuron, isouron, isocarba mid, isoxachlortole, isoxapyrifop, isoxa?utole, isoxaben, iso cil, isonoruron, isoproturon, isopropalin, isopolinate, isomethiozin, inaben?de, ipaZine, ipfencarbazone, iprymi dam, imazaquin, imazapic, imazapyr, imazamethapyr, imazamethabenZ, imazamethabenZ-methyl, imazamox, imazethapyr, imazosulfuron, indaZi?am, indanofan, indole butyric acid, uniconazole-P, eglinaZine, esprocarb, ethamet sulfuron, ethametsulfuron-methyl, ethal?uralin, ethiolate, ethychlozate-ethyl, ethidimuron, etinofen, ethephon, ethox ysulfuron, ethoxyfen, etnipromid, ethofumesate, etobenza nid, epronaZ, erbon, endothal, oxadiazon, oxadiargyl, ovai clomefone, oxasulfuron, oxapyrazon, oxy?uorfen, oryzalin, orthosulfamuron, orbencarb, cafenstrole, cambendichlor, carbasulam, carfentrazone, carfentrazone-ethyl, karbutilate, carbetamide, carboxazole, quizalofop, quizalofop-P, quizalo fop-ethyl, xylachlor, quinoclamine, quinonamid, quinclorac, quinmerac, cumyluron, clacyfos, cliodinate, glyphosate, glu fosinate, glufosinate-P, credaZine, clethodim, cloxyfonac, clodinafop, clodinafop-propargyl, clopyralid, cloproxydim, cloprop, clofop, clomazone, chlomethoxynil, chlomethoxy fen, clomeprop, chloraZifop, chloraZine, chloranocryl, chloramben, cloransulam, cloransulam-methyl, chloridazon, chlorimuron, chlorimu ron-ethyl, chlorsulfuron, chlorthal, chlorthiamid, chlortolu ron, chlomitrofen, chlorfenac, chlorfenprop, chlorbufam, chlor?urazole, chlor?urenol, chlorprocarb, chlorpropham, chlorbromuron, chlormequat, chloreturon, chloroxynil, chloroxuron, chlorotoluron, chloropon, sa?ufenacil, cyana Zine, cyanatryn, di-allate, diuron, diethamquat, dicamba, cycluron, cycloate, cycloxydim, diclosulam, cyclosulfamu ron, dichlorprop, dichlorprop-P, dichlobenil, diclofop, diclo fop-methyl, dichlormate, dichloralurea, diquat, cisanilide, disul, siduron, dithiopyr, dinitramine, cinidon-ethyl, dinosam, cinosulfuron, dinoseb, dinoterb, dinofenate, dino prop, cyhalofop-butyl, diphenamid, difenoxuron, difeno penten, difenzoquat, cybutryne, cypraZine, cyprazole, di?ufenican, di?ufenzopyr, dipropetryn, cypromid, cyper quat, gibberellin, simaZine, dimidazon, dimexano, dimeth achlor, dimethametryn, dimethenamid, simetryn, simeton, dimepiperate, dimefuron, cinmethylin, swep, sulglycapin, sulcotrione, sulfallate, sulfentrazone, sulfosulfuron, sulfo meturon, sulfometuron-methyl, secbumeton, sethoxydim, sebuthylaZine, terbacil, daimuron, dazomet, dalapon, thiaZ a?uoron, thiazopyr, thiencarbazone, thiencarbazone-methyl, tiocarbaZil, tioclorim, thiobencarb, thidiaZimin, thidiazuron, thifensulfuron, thifensulfuron-methyl, desmedipham, desm etryn, tetra?uoron, thenylchlor, tebutam, tebuthiuron, terbu meton, tepraloxydim, tefuryltrione, tembotrione, delachlor, terbacil, terbucarb, terbuchlor, terbuthylaZine, terbutryn, topramezone, tralkoxydim, triaZi?am, triasulfuron, triafa mone, tri-allate, trietaZine, tricamba, triclopyr, tridiphane, tritac, tritosulfuron, tri?usulfuron, tri?usulfuron-methyl, tri ?uralin, tri?oxysulfuron, tripropindan, tribenuron, tribenuron-methyl, trifop, trifopsime, trimeturon, naptalam, naproanilide, napropamide, nicosulfuron, nitralin, nitrofen, nitro?uorfen, nipyraclofen, neburon, nor?urazon, noruron, barban, paclobutrazol, paraquat, para?uoron,
US 2014/0256687 A1
haloxydine, haloxyfop, haloxyfop-P, haloxyfop-methyl, halosafen, halosulfuron, halosulfuron-methyl, bilanafos, picloram, picolinafen, bicyclopyrone, bispyribac, bispyribac sodium, pydanon, pinoxaden, bifenox, piperophos, hymex azol, pyraclonil, pyrasulfotole, pyrazoxyfen, pyrazosulfuron, pyrazosulfuron-ethyl, pyrazolate, bilanafos, pyra?ufen ethyl, pyriclor, pyridafol, pyrithiobac, pyrithiobac-sodium, pyridate, pyri?alid, pyribu ticarb, pyribenzoxim, pyrimisulfan, primisulfuron, pyrimino bac-methyl, pyroxasulfone, pyroxsulam, fenasulam, phen isopham, fenuron, fenoxasulfone, fenoxaprop, fenoxaprop-P, fenoxaprop-ethyl, phenothiol, fenoprop, phenobenzuron, fenthiaprop, fenteracol, fentrazamide, phenmedipham, phen medipham-ethyl, butachlor, butafenacil, butamifos, buthi uron, buthidazole, butylate, buturon, butenachlor, butroxy dim, butralin, butroxydim, ?azasulfuron, ?amprop, furyloxyfen, prynachlor, primisulfuron-methyl, ?uaZifop, ?uaZifop-P, ?uaZifop-butyl, ?uazolate, ?uoroxypyr, ?uothiuron, ?uometuron, ?uorogly cofen, ?uorochloridone, ?uorodifen, ?uoronitrofen, ?uoro midine, ?ucarbazone, ?ucarbazone-sodium, ?uchloralin, ?u cetosulfuron, ?uthiacet, ?uthiacet-methyl, ?upyrsulfuron, ?ufenacet, ?ufenican, ?ufenpyr, ?upropacil, ?upropanate, ?upoxam, ?umiovain, ?umiclorac, ?umiclorac-pentyl, ?u mipropyn, ?umeZin, ?umetsulam, ?uridone, ?urtamone, ?u oroxypyr, pretilachlor, proxan, proglinaZine, procyaZine, prodiamine, prosulfalin, prosulfuron, prosulfocarb, propaquizafop, propachlor, propaZine, propa nil, propyzamide, propisochlor, prohydrojasmon, propyrisul furon, propham, pro?uazol, pro?uralin, prohexadione-cal cium, propoxycarbazone, propoxycarbazone-sodium, profoxydim, bromacil, brompyrazon, prometryn, prometon, bromoxynil, bromofenoxim, bromobutide, bromobonil, ?o rasulam, hexachloroacetone, hevainone, pethoxamid, bena zolin, penoxsulam, pebulate, be?ubutamid, vemolate, per ?uidone, bencarbazone, benzadox, benZipram, benzylaminopurine, benZthiazuron, beanendizone, ben sulide, bensulfuron-methyl, benzoylprop, benzobicyclon, benzofenap, benzo?uor, bentazone, pen tanochlor, benthiocarb, pendimethalin, pentoxazone, ben?u ralin, benfuresate, fosamine, fomesafen, foramsulfuron, forchlorfenuron, maleic hydraZide, mecoprop, mecoprop-P, medinoterb, mesosulfuron, mesosulfuron-methyl, mesotri one, mesopraZine, methoprotryne, metazachlor, methazole, metazosulfuron, methabenZthiazuron, metamitron, metami fop, metam, methalpropalin, methiuron, methiozolin, methiobencarb, methyldymron, metoxuron, meto sulam, met sulfuron, metsulfuron-methyl, met?urazon, metobromuron, metobenzuron, methometon, metolachlor, metribuZin, mepi quat-chloride, mefenacet, me?uidide, monalide, monisou ron, monuron, monochloroacetic acid, monolinuron, moli nate, morfamquat, iodosulfuron, iodosulfuron-methyl sodium, iodobonil, iodomethane, lactofen, linuron, rimsulfuron, lenacil, rhodethanil, calcium peroxide and methyl bromide. [0055] Examples of the synergists include piperonyl butox ide, sesamex, sulfoxide, N-(2-ethylhexyl)-8,9,10-trinorbom 5-ene-2,3-dicarboximide (MGK 264), N-declyimidazole, WARF-antiresistant, TBPT, TPP, IBP, PSCP, methyl iodide, t-phenylbutenone, diethyl maleate, DMC, FDMC, ETP and ETN.
[0056] Examples of the phytotoxicity reducers include benoxacor, cloquintocet-mexyl, cyometrinil, daimuron, dichlormid, cyprosulfamide, fenchlorazole-ethyl, fenclorim,
Sep. 11,2014
?urazole, ?uxofenim, furilazole, mefenpyr-diethyl, MG191, oxabetrinil, allidochlor, isoxadifen-ethyl, cyprosulfamide, ?uxofenim and 1,8-naphthalic anhydride.
EXAMPLES
[0057] Hereinafter, representative Examples and Test Examples in connection with the present invention are shown, but the present invention is not limited thereto. In Examples, the “part(s)” means a part(s) by mass.
Formulation Example 1
Emulsi?able Concentrate
[0058]
Flubendialnide 5 parts Dichlorvos 10 parts Xylene 65 parts N—methyl pyrrolidone 10 parts Mixture of polyoxyethylene nonylphenyl ether 10 parts and calcium alkylbenzene sulfonate
[0059] The above ingredients are mixed and dissolved uni formly to give an emulsi?able concentrate.
Formulation Example 2
Dust
[0060]
Flubendialnide 3 parts Profenofos 10 parts Clay powder 72 parts Diatomite powder 15 parts
[0061] The above ingredients are uniformly mixed and then pulverized to give a dust.
Formulation Example 3
Granule
[0062]
Flubendialnide 1 part Dichlorvos 2 parts Profenofos 2 parts Mixture of bentonite powder and clay powder 90 parts Calcium lignosulfonate 5 parts
[0063] The above ingredients are uniformly mixed. After addition of an appropriate volume of water, the mixture is kneaded, granulated and dried to give a granule.
Formulation Example 4
Wettable Powder
[0064]
Flubendialnide 2 parts Dichlorvos 18 parts
US 2014/0256687 A1
-c0ntinued
Kaolin and synthetic high—dispersion silicic 75 parts acid Mixture of polyoxyethylene nonylphenyl ether 5 parts and calcium alkylbenzene sulfonate
[0065] The above ingredients are uniformly mixed and then pulverized to give a wettable powder.
Formulation Example 5
Sep. 11,2014 11
regarded as having not a mere additive effect but a synergistic effect. The results are shown in Table 1.
[0069] Ta?he number of surviving larvae after the agro chemical treatment in a treatment plot [0070] Tb?he number of surviving larvae before the agro chemical treatment in a treatment plot [0071] Ca?he number of surviving larvae after the agro chemical treatment in a non-treatment plot
<Formula 1>
[0072] Cb?he number of surviving larvae before the agro Flowable chemical treatment in a non-treatment plot
[0066] Colby’s equation E (expected value):(X+Y)—(X>< Y/100)
Flub?ndiamide 5 pans [0073] X?he control effect of ?ubendiamide alone Profenofos 25 parts [007 4] Y?he control effect of d1ch10rvos or profenofos
alone
TABLE 1
Number of surviving larvae Control effect (%) Expected value (%)
2 days 6 days 2 days 6 days 2 days 6 days Dose Before after after after after after after
Test agrochemical (g a.i./ha) treatment treatment treatment treatment treatment treatment treatment
Flubendiamide 60 575 207 30 62 94 49 88 Dichlorvos 400 Flubendiamide 60 373 51 13 86 96 68 98 Profenofos 320 Flubendiamide 60 533 307 56 39 88 i *
Dichlorvos 400 236 188 212 16 O i i
Profenofos 320 246 121 44 48 80 i i
Non—treatment i 348 329 314 i i i i
The a.i. in the table stands for active ingredient.
-00ntinued Test Example 2
So 01 3105 manufactured b Toho Chemical 5 arts _ _ Inigstry CO_ (ML Japan) y p Control Effect on Chzlo suppressalzs Propylene glycol 5 parts 151353101’01 23 (manufacmr?d by Rhon?'POUlenc 2 PMS [0075] Rice plants (variety: Kinmaze) were planted in 2-L Wat-6r 58 pans pots and grown to a height of about 80 cm (about 82 days after
transplantation, 18 to 25 sheaths). The depth of paddy water . . . . in each 0t was ad'usted t0 4 cm and then s ra treatment to
[0067] The above 1ngred1ents are uniformly mixed and then p J p y dispersed in water to give a ?owable.
Test Example 1
Control Effect on Plulella xyloslella
[0068] Transplants ofBrassica oleracea var. capilala (vari ety: YR Seitoku) were planted in a glass greenhouse, and in the 12- t0 15-leaf stage, inoculated with 3rd-instar larvae of Plulella xyloslella. The number of surviving larvae in three plants per plot before agrochemical treatment was counted and then spray treatment to the test plants was conducted with an agrochemical solution diluted to a predetermined concen tration in an amount equivalent to 800 L/ha. The number of surviving larvae was counted at 2 and 6 days after the spray treatment and the control effect was calculated according to formula 1. In addition, the expected value for the control effect of the mixed use was calculated according to Colby’s equation shown below. When the control effect of the mixed use is superior to the expected value, the mixed use is
the rice plants was conducted with an agrochemical solution
diluted to a predetermined concentration in an amount
equivalent to 400 L/ha. After the spray-treated plants were air-dried, each pot was covered with a vinyl chloride cylin drical cover 30 cm in height. At 1 day before the treatment and
at 5 and 12 days after the treatment, 20 larvae of the test insect pest Chilo suppressalis were released into each of the covered
pots (60 larvae in total per pot). At 29 days after the treatment, in each pot, the number of damaged stems of the rice plants was counted, the percentage of damaged stems was calcu lated, and from this percentage, the control effect was calcu lated according to formula 2. In addition, the expected value was calculated according to Colby’s equation in the same manner as in Test Example 1. The results are shown in Table
2.
Control effect (%):100—(the percentage of damaged stems in a treatment plot/the percentage of dam— aged stems in a non—treatment plot)><100 <Formula 2>
US 2014/0256687 A1
TABLE 2
Sep. 11,2014
Number of stems at 29 days Percentage of Dose after treatment damaged stems Percentage of Expected
Test agrochemical (g a.i./ha) Normal stems Damaged stems (%) control (%) value (%)
Flubendiamide 30 58 0 0 100 57.5 Dichlorvos 393 Flubendiamide 30 49 2 3.9 95.7 66.7 Profenofos 500 Flubendiamide 30 29 21 42.0 54.0 i
Dichlorvos 393 7 3 8 84.4 7.5 i
Profenofos 500 18 35 66.0 27.7 i
Non—treatment i 4 42 91.3 i i
The a.i. in the table stands for active ingredient.
[0076] In each test, the control effects observed in (i) the ?ubendiamide and dichlorvos mixed treatment plot and in (ii) the ?ubendiamide and profenofos mixed treatment plot were greater than the expected effect (expected value) calculated from the effect observed in the ?ubendiamide treatment plot and the effect observed in the dichlorvos or profenofos treat ment plot.
1. An agricultural and horticultural insecticide composi tion comprising ?ubendiamide and dichlorvos and/or pro fenofos as active ingredients.
2. The agricultural and horticultural insecticide composi tion according to claim 1, comprising 0.1 to 10 parts by mass of dichlorvos and/or profenofos per part by mass of ?uben diamide.
3. A method for using an agricultural and horticultural insecticide composition, comprising treating insect pests directly, treating crops potentially infested with the insect pests, or treating surrounding soil or cultivation medium of the crops with an effective amount of an agricultural and horticultural insecticide composition comprising ?ubendia mide and dichlorvos and/or profenofos as active ingredients.
4. A method for controlling agricultural and horticultural insect pests, comprising treating insect pests directly, treating crops potentially infested with the insect pests, or treating surrounding soil or cultivation medium of the crops with an
effective amount of an optionally diluted formulation con taining ?ubendiamide as an active ingredient and an effective amount of an optionally diluted formulation containing dichlorvos and/or profenofos as an active ingredient(s), the two formulations being used separately but in the same period.
5. A method for controlling agricultural and horticultural insect pests, comprising treating insect pests directly, treating crops potentially infested with the insect pests, or treating surrounding soil or cultivation medium of the crops with an effective amount of an optionally diluted formulation con taining ?ubendiamide as an active ingredient and an effective amount of an optionally diluted formulation containing dichlorvos and/or profenofos as an active ingredient(s), the two formulations being used separately at a given interval.
6. A method for controlling agricultural and horticultural insect pests, comprising mixing an effective amount of a formulation containing ?ubendiamide as an active ingredient and an effective amount of a formulation containing dichlo rvos and/or profenofos as an active ingredient(s), optionally diluting the mixture; and treating insect pests directly, treat ing crops potentially infested with the insect pests, or treating surrounding soil or cultivation medium of the crops with the optionally diluted mixture.
* * * * *
