Warm-Up Monday Nov. 5, 2012 List the two components that make
up the backbone "of DNA.
Slide 2
Warm- Up Tuesday Nov. 6, 2012 Define translation in your own
words.
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Protein Synthesis
Slide 4
Objectives 1.Define the term protein synthesis 2.Relate
translation to the process of protein synthesis 3.Describe the role
of RNA in protein synthesis
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Protein Synthesis Synthesis = to make Protein synthesis = to
make proteins Translation = process of synthesizing proteins
Slide 6
Translation: Review Translation = process of decoding mRNA to
produce a sequence of amino acids in a chain (protein) mRNA =
messenger RNA Amino Acids = building blocks of DNA Location:
cytoplasm
Slide 7
Translation: Review Which process must occur before translation
can take place?
Slide 8
Translation 1) mRNA attaches to ribosome 2) tRNA brings amino
acids (a.acids) to ribosome 3) A. acids attached along assembly
line 4) Continues until a stop codon is reached
Slide 9
Translation: making proteins from amino acids
Slide 10
Making Proteins Sequence of nucleotides = instructions for the
order of amino acids Proteins = long chain of a. acids Code is read
3 letters at a time
Slide 11
Codon = sequence of three nucleotides in DNA & RNA Each
codon codes for proper amino acid Example: AUG-CGU-AAC-UGA
Review: RNAs role in Protein Synthesis Type
RNAAbbreviationFunction Messenger RNA mRNACarry copies of
instructions for making proteins Ribosomal RNArRNAMakes up
ribosomes Transfer RNAtRNABrings specific a.acids to ribosome
according to mRNA instructions
Slide 14
DNA Rap http://www.dnatube.com/video/3446/BioRap-DNA-
Replication-and-Protein-Synthesis-with-a-Beat
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Avid Thinking Strategy: Protein Synthesis Rap/Rhyme Directions
(#11 on pg 11) - Concept: Protein Synthesis - Rap/Rhyme
requirements: 1) Title (reflects main concept of poem) 2 ) Minimum
2 stanzas 4 lines each ( grouping of lines, set off by a space,
that usually has a set pattern of meter and rhyme) 3) Illustration
depicting concept of poem (2 colors) 4) 4 sentence explanation
explaining how the song & illustration demonstrate the concept
of protein synthesis
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Warm Up Wednesday Nov. 7, 2012 1. Define the word codon. 2.
List one START codon and one STOP codon.
Slide 17
Warm Up Thursday Nov. 8, 2012 What organelle does translation
occur in?
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Chromosomal Mutations
Slide 19
Objectives 1. Define chromosomal mutation. 2. List and discuss
common chromosomal mutations found in the human body.
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Chromosomal Mutations = change in the # or structure of
chromosomes 4 types: 1) Inversion 2) Translocation 3) Deletion 4)
Duplication
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1) Inversion = segment of chromosome breaks off & is
reinserted in the same place but in reverse direction Causes
increased risk of miscarriages
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2) Translocation = one of 2 homologous chromosomes breaks &
binds to the other Causes cancer & Infertility Very deadly
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3) Deletion = Lose portion of chromosome Example:
Wolf-Hirschhorn Syndrome
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Wolf-Hirschhorn Syndrome Description: condition that is caused
by a missing part (deletion) of the short arm of chromosome 4
Symptoms: Severe developmental delays Characteristic facial
appearance Seizures Variety other birth defects
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4) Duplication = portion chromosome copied, resulting in extra
genetic material Example: Charcot-Marie-Tooth Disease
Slide 26
Charcot-Marie-Tooth Disease Description: Progressive loss of
muscle tissue and touch sensation across various parts of the body
Symptoms: muscle weakness decreased muscle bulk Tends to slowly
worsen over time
Slide 27
Avid Thinking Strategy: Letter to the Editor Directions (#13 pg
11) Concept: Chromosomal Mutations Letter Requirements: 1) 2-3
paragraphs (minimum 5 sentences each) 2) Write a letter about why
mutations are harmful to humans 3) Use the new vocabulary words
learned (in notes) 4) You must state an opinion and use 5 specific
facts to support that opinion. 5) There must be an illustration
depicting the concept of mutations.
Slide 28
Warm Up Friday Nov. 9, 2012 What organelle does transcription
occur in?
