Yes, without leaving our own library, a pre­cursory patent and literature search revealed 135 possible industrial applications for PIPERAZINE and its derivatives. This potential industrial work­horse may be just the starting material or inter­mediate you're seeking in your research program.

The chemical structure shows piperazine to be a cyclic secondary diamine comprising a six-membered heterocycle with the nitrogens in the para positions. In the pure state, it is a white, hygroscopic, crystalline solid, with a mild odor typical of amines. Piperazine behaves chemically as might be expected of a secondary amine. It forms salts with inorganic acids, but with organic acids, either the salt or the amide may result, depending on the conditions. Similar amidation occurs with anhydrides, acid chlorides, and esters.

Jefferson

To assist you in evaluating the potential of piperazine, we offer the results of our survey in a conveniently indexed brochure. Each reference contains a concise and informative abstract of the original article from which it was taken.

Jefferson is the largest producer of piperazine, and a number of forms are marketed including the anhydrous and hydrated products, as well as the salts of organic and inorganic acids. Our technical service people will be glad to provide samples and work closely with you in your appli­cation evaluations of piperazine. For further in­formation and your personal copy of our pipera­zine survey, write on your company letterhead to . . . Jefferson Chemical Company, Inc., P. O. Box 53300, Houston, Texas 77052.

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We found 135 applications without even trying!