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IT’S ALL ABOUT SIZEIT’S ALL ABOUT SIZE
THERE IS AN UPPER LIMIT TO THERE IS AN UPPER LIMIT TO HOW LARGE A CELL CAN BEHOW LARGE A CELL CAN BE
WHY DO CELLS DIVIDE?WHY DO CELLS DIVIDE?
1. Diffusion– A cell must move all materials needed for
functioning via diffusion through cytoplasm
WHY DO CELLS DIVIDE?WHY DO CELLS DIVIDE?
1. Diffusion– A cell must move all materials needed for
functioning via diffusion through cytoplasm– It takes a fraction of a second for materials
to move from the plasma membrane to the center of a typical cell with a diameter of 20 µm
WHY DO CELLS DIVIDE?WHY DO CELLS DIVIDE?
1. Diffusion– A cell must move all materials needed for
functioning via diffusion through cytoplasm– It takes a fraction of a second for materials
to move from the plasma membrane to the center of a typical cell with a diameter of 20 µm
– If a cell were 20 cm in diameter, it would take months to move materials from the plasma membrane to the center of the cell
WHY DO CELLS DIVIDE?WHY DO CELLS DIVIDE?
2. DNA– A cell must respond to changing conditions
rapidly– A cell frequently needs to produce large
amounts of proteins and enzymes
WHY DO CELLS DIVIDE?WHY DO CELLS DIVIDE?
2. DNA– The process by which proteins and enzymes
are made is complicated• DNA makes an RNA copy of the gene to be
copied• RNA leaves the nucleus and travels to a
ribosome• RNA directs protein production at the ribosome
WHY DO CELLS DIVIDE?WHY DO CELLS DIVIDE?
2. DNA– If there is not enough DNA to rapidly carry
out RNA production, the metabolism will slow and the cell will die
WHY DO CELLS DIVIDE?WHY DO CELLS DIVIDE?
2. DNA
Larger cell = Greater metabolism
Greater metabolism = More DNA needed to direct metabolism
WHY DO CELLS DIVIDE?WHY DO CELLS DIVIDE?
3. Surface area-to-volume ratio– As the size of any object increases, volume
increases at a much greater rate than does surface area
WHY DO CELLS DIVIDE?WHY DO CELLS DIVIDE?
3. Surface area-to-volume ratio– As the size of any object increases, volume
increases at a much greater rate than does surface area
– A cell receives all the materials needed for life through its plasma membrane
WHY DO CELLS DIVIDE?WHY DO CELLS DIVIDE?
3. Surface area-to-volume ratio– Larger organisms (or cells) need more
“stuff”: you require more food than does a two-year-old human
WHY DO CELLS DIVIDE?WHY DO CELLS DIVIDE?
3. Surface area-to-volume ratio– Larger organisms (or cells) need more
“stuff”: you require more food than does a two-year-old human
– As the volume of a cell increases, it needs more and more materials to be passed through the plasma membrane in order to sustain life