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Day 1: Wednesday 26th August 2020 09:10 - 09:15 Attendees login 09:15 - 09:30 Welcome and introduction (Chair: Shi-qi An) 09:30 - 10:15 Special lecture: Zheng Zhang (Southern University of Science and Technology, CN) (Chair: Jeremy Webb) "Immunopathogenesis and antibody responses elicited by SARS-CoV-2 infection" 10:15 - 10:25 Coffee break Session I: Secretion and transport across membranes (Chair: Clare Kirkpatrick) 10:25 - 10:45 Suzan Rooijakkers (Utrecht University, NL) “How complement molecules kill Gram-negative bacteria" 10:45 - 11:05 Patricia Bernal (University of Seville, ES) "Novel structural components generate distinct type VI secretion system anchoring modes" 11:05 - 11:25 Yiming Cai (Université Toulouse III - Paul Sabatier, FR) "Mechanism of NTase-like family toxin-antitoxin systems in Mycobacterium" 11:25 - 11:45 Christopher Mahone (Johns Hopkins School of Medicine, US) "Linking the Z-ring to cell wall remodelling for constriction during bacterial cytokinesis" 11:45 - 12:00 Group photo 12:00 - 13:00 Lunch break/ePoster session Meeting Room 1 (Poster No. 001-030); Meeting Room 2 (Poster No. 031-060); Meeting Room 3 (Meet the Editor); Meeting Room 4 (Exhibition) Hot-spot talks: Part I (Chair: Sandra Wilks) 13:00 - 13:10 Introduction to hot-spot talks 13:10 - 14:00 Hot-spot talks 14:00 - 14:25 Hot-spot talks Q&A 14:25 - 14:35 Coffee break 14:35 - 15:20 Special lecture: Mark Golmesky (University of Wyoming, US) (Chair: Shi-qi An) "Bacterial signalling modules for biomedical applications" 15:20 - 15:30 Coffee break Session II: Gene regulation and signalling (Chair: Bruno Lopes) 15:30 - 15:50 Jacob Malone (John Innes Centre, UK) "Control of mRNA translation by dynamic ribosome modification" 15:50 - 16:10 Elena Pajares Martínez (University of Murcia, ES) "A bacterial light response reveals a signalling role for plasmalogens and a long-sought lipid desaturase for human plasmalogen synthesis" 16:10 - 16:30 Veronica Urdaneta (Yale University, US) "Riboswitch reporters to assess selective permeability and active efflux in Pseudomonas aeruginosa" 16:30 - 16:50 Joan Geoghegan (University of Birmingham, UK) "First contact - Adhesion of Staphylococcus aureus to skin corneocytes in atopic dermatitis" 16:50 - 17:00 Organising team announcement Day 2: Thursday 27th August 2020 08:55 - 09:00 Attendees login 09:00 - 09:10 Introduction (Chair: Clare Kirkpatrick) 09:10 - 09:40 César Sánchez (Nature Communications, UK) (Chair: Clare Kirkpatrick) "Publish, not perish" 9:40 - 9:50 Coffee break Session III: Host-microbe interactions (Chair: Bruno Lopes) 9:50 - 10:10 Priscille Brodin (Institut Pasteur, FR) “TBA" 10:10 - 10:30 Connor Sharp (University of Oxford, UK) "Coevolution of host control in the animal microbiome" 10:30 - 10:50 Lisanne de Vor (Utrecht University, NL) "Development of antibodies that enhance immune clearance of staphylococcal biofilm infections" 10:50 - 11:10 Liang Yang (Southern University of Science and Technology, CN) "Comparative analysis of Pseudomonas aeruginosa biofilm-associated infections" 11:10 - 11:20 Coffee break 11:20 - 12:05 Special lecture: Lotte Sogaard-Andersen (Max Planck Institute, DE) (Chair: Clare Kirkpatrick) "Structure & function of the type IV pilus machine: The minor pilins & PilY1" 12:05 - 13:05 Lunch break/ePoster session Meeting Room 1 (Poster No. 061-090); Meeting Room 2 (Poster No. 091-120); Meeting Room 3 (Meet the Editor); Meeting Room 4 (Exhibition) Hot-spot talks: Part II (Chair: Liang Yang) 13:05 - 13:15 Introduction to hot-spot talks 13:15 - 14:05 Hot-spot talks 14:05 - 14:30 Hot-spot talks Q&A 14:30 - 14:40 Coffee break Session IV: Microbial communities and biofilm formation (Chair: Jo Slater-Jefferies) 14:40 - 15:00 Brendan Gilmore (Queen’s University Belfast, UK) "Non thermal plasmas for controlling Pseudomonas aeruginosa biofilms" 15:00 - 15:20 Mary Turley (Trinity College Dublin, IE) "Polysaccharide-dependent biofilm formation can be induced by bile in cystic fibrosis clinical isolates of Staphylococcus aureus" 15:20 – 15:40 Hannah Serrage (University of Bristol, UK) "Elucidating the role of extracellular DNA in oral biofilm formation" 15:40 - 16:00 Gabriele Berg (Graz University of Technology, AT) "The environmental microbiome explored: impact for planetary health" 16:00 - 16:10 Coffee break 16:10 - 16:55 Special lecture: Marvin Whiteley (Georgia Institute of Technology, US) (Chair: Shi-qi An) "Quantifying the accuracy of infection models: From function to biogeography" 16:55 – 17:15 Closing remarks and Prizes (Chair: Lindy Holden-Dye) @YMS2020Soton [email protected]

@YMS2020Soton [email protected] Day 2: Thursday ......"Non thermal plasmas for controlling Pseudomonas aeruginosa biofilms" 15:00 -15:20 Mary Turley (Trinity College Dublin, IE)

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Page 1: @YMS2020Soton YMS2020@soton.ac.uk Day 2: Thursday ......"Non thermal plasmas for controlling Pseudomonas aeruginosa biofilms" 15:00 -15:20 Mary Turley (Trinity College Dublin, IE)

Day 1: Wednesday 26th August 202009:10 - 09:15 Attendees login09:15 - 09:30 Welcome and introduction (Chair: Shi-qi An)

09:30 - 10:15 Special lecture: Zheng Zhang (Southern University of Science and Technology, CN) (Chair: Jeremy Webb)"Immunopathogenesis and antibody responses elicited by SARS-CoV-2 infection"

10:15 - 10:25 Coffee break Session I: Secretion and transport across membranes (Chair: Clare Kirkpatrick)

10:25 - 10:45 Suzan Rooijakkers (Utrecht University, NL)“How complement molecules kill Gram-negative bacteria"

10:45 - 11:05 Patricia Bernal (University of Seville, ES)"Novel structural components generate distinct type VI secretion system anchoring modes"

11:05 - 11:25 Yiming Cai (Université Toulouse III - Paul Sabatier, FR)"Mechanism of NTase-like family toxin-antitoxin systems in Mycobacterium"

11:25 - 11:45 Christopher Mahone (Johns Hopkins School of Medicine, US)"Linking the Z-ring to cell wall remodelling for constriction during bacterial cytokinesis"

11:45 - 12:00 Group photo12:00 - 13:00 Lunch break/ePoster session

Meeting Room 1 (Poster No. 001-030); Meeting Room 2 (Poster No. 031-060);Meeting Room 3 (Meet the Editor); Meeting Room 4 (Exhibition)

Hot-spot talks: Part I (Chair: Sandra Wilks)13:00 - 13:10 Introduction to hot-spot talks13:10 - 14:00 Hot-spot talks14:00 - 14:25 Hot-spot talks Q&A14:25 - 14:35 Coffee break14:35 - 15:20 Special lecture: Mark Golmesky (University of Wyoming, US) (Chair: Shi-qi An)

"Bacterial signalling modules for biomedical applications"15:20 - 15:30 Coffee break

Session II: Gene regulation and signalling (Chair: Bruno Lopes)

15:30 - 15:50 Jacob Malone (John Innes Centre, UK)"Control of mRNA translation by dynamic ribosome modification"

15:50 - 16:10 Elena Pajares Martínez (University of Murcia, ES)"A bacterial light response reveals a signalling role for plasmalogens and a long-sought lipid desaturase for human plasmalogen synthesis"

16:10 - 16:30 Veronica Urdaneta (Yale University, US) "Riboswitch reporters to assess selective permeability and active efflux in Pseudomonas aeruginosa"

16:30 - 16:50 Joan Geoghegan (University of Birmingham, UK)"First contact - Adhesion of Staphylococcus aureus to skin corneocytes in atopic dermatitis"

16:50 - 17:00 Organising team announcement

Day 2: Thursday 27th August 202008:55 - 09:00 Attendees login09:00 - 09:10 Introduction (Chair: Clare Kirkpatrick)09:10 - 09:40 César Sánchez (Nature Communications, UK) (Chair: Clare Kirkpatrick)

"Publish, not perish"9:40 - 9:50 Coffee break

Session III: Host-microbe interactions (Chair: Bruno Lopes)

9:50 - 10:10 Priscille Brodin (Institut Pasteur, FR)“TBA"

10:10 - 10:30 Connor Sharp (University of Oxford, UK)"Coevolution of host control in the animal microbiome"

10:30 - 10:50 Lisanne de Vor (Utrecht University, NL)"Development of antibodies that enhance immune clearance of staphylococcal biofilm infections"

10:50 - 11:10 Liang Yang (Southern University of Science and Technology, CN)"Comparative analysis of Pseudomonas aeruginosa biofilm-associated infections"

11:10 - 11:20 Coffee break11:20 - 12:05 Special lecture: Lotte Sogaard-Andersen (Max Planck Institute, DE) (Chair: Clare Kirkpatrick)

"Structure & function of the type IV pilus machine: The minor pilins & PilY1"12:05 - 13:05 Lunch break/ePoster session

Meeting Room 1 (Poster No. 061-090); Meeting Room 2 (Poster No. 091-120);Meeting Room 3 (Meet the Editor); Meeting Room 4 (Exhibition)

Hot-spot talks: Part II (Chair: Liang Yang)

13:05 - 13:15 Introduction to hot-spot talks13:15 - 14:05 Hot-spot talks14:05 - 14:30 Hot-spot talks Q&A14:30 - 14:40 Coffee break

Session IV: Microbial communities and biofilm formation (Chair: Jo Slater-Jefferies)

14:40 - 15:00 Brendan Gilmore (Queen’s University Belfast, UK)"Non thermal plasmas for controlling Pseudomonas aeruginosa biofilms"

15:00 - 15:20 Mary Turley (Trinity College Dublin, IE)"Polysaccharide-dependent biofilm formation can be induced by bile in cystic fibrosis clinical isolates of Staphylococcus aureus"

15:20 – 15:40 Hannah Serrage (University of Bristol, UK)"Elucidating the role of extracellular DNA in oral biofilm formation"

15:40 - 16:00 Gabriele Berg (Graz University of Technology, AT)"The environmental microbiome explored: impact for planetary health"

16:00 - 16:10 Coffee break16:10 - 16:55 Special lecture: Marvin Whiteley (Georgia Institute of Technology, US) (Chair: Shi-qi An)

"Quantifying the accuracy of infection models: From function to biogeography"16:55 – 17:15 Closing remarks and Prizes (Chair: Lindy Holden-Dye)

@YMS2020Soton

[email protected]

Page 2: @YMS2020Soton YMS2020@soton.ac.uk Day 2: Thursday ......"Non thermal plasmas for controlling Pseudomonas aeruginosa biofilms" 15:00 -15:20 Mary Turley (Trinity College Dublin, IE)

Day 1: Wednesday 26th August 2020

13:10 - 14:00 Hot-spot talksHot-spot talk 1 Danny Ward (John Innes Centre, UK)

"Control of type III-mediated virulence by cyclic-di-GMP in Pseudomonas syringae"Hot-spot talk 2 Guanbo Wang (Queen's University Belfast, UK)

"A glycoengineered antigen exploiting a conserved protein O-glycosylation pathway in the Burkholderia genus for diagnosis of glanders infections"

Hot-spot talk 3 Funto ajayi (University of Ibadan, NG)Evaluation of some nodulation genes found in bambara symbiotic rhizobia strains

Hot-spot talk 4 Katie Horton (University of Southampton, UK)"Non-typeable Haemophilus influenzae biofilm formation on primary airway epithelium"

Hot-spot talk 5 Krisztina Nagy (University of Szeged, HU)"Evolution of antibiotic resistance in structured environments"

Hot-spot talk 6 Ronan McCarthy (Brunel University London, UK)"An invertebrate burn wound model that recapitulates the hallmarks of burn"

Hot-spot talk 7 Sergii Krysenko (University of Tübingen, DE)"Validation of a target for development of novel anti-tubercular drugs"

Hot-spot talk 8 Stephanie de Sousa (University of São Paulo, BR)"A family of T6SS antibacterial effectors related to L,D-transpeptidases targets the peptidoglycan"

Hot-spot talk 9 Verena Vogel (University hospital Ulm, DE)"Killing of competitors-bacteriocin production of Streptococcus anginosus"

Hot-spot talk 10 Yoann Santin (CNRS Laboratoire d'Ingénierie des Systèmes Macromoléculaires, FR)"In vivo proximity labelling unveils the molecular mechanism of T6SS tail length control"

Day 2: Thursday 27th August 2020

13:15 - 14:05 Hot-spot talks

Hot-spot talk 11 Annika Cimdins-Ahne (University of Muenster, DE)"Staying or leaving: c-di-GMP regulated cell behavior in probiotic E. coli Nissle 1917"

Hot-spot talk 12 Cai Zhao (Southern University of Science and Technology, CN)"Metagenomics reveals a core macrolide resistome related to microbiota in chronic respiratory disease"

Hot-spot talk 13 Catrione Lee (Lethbridge Research and Development Centre, CA)"Antimicrobial resistance profiles of bovine respiratory disease pathogens from cattle upon arrival at Canadian feedlots"

Hot-spot talk 14 Erifyli Tsagkari (University of Glasgow, UK)"Combination of computational modelling and 3-D printing to engineer biofilm and shear interaction"

Hot-spot talk 15 James Butler (University of Plymouth, UK)"Development of a novel antibacterial silver nanocoating to reduce nosocomial infections"

Hot-spot talk 16 Jiarui Li (Universitat Autònoma de Barcelona, ES)"Testing a human antimicrobial RNase chimera against bacterial resistance"

Hot-spot talk 17 Maria Vittoria Mazzuoli (Institut Pasteur, FR)"Regulatory evolution of virulence in Group B Streptococcus"

Hot-spot talk 18 René Bærentsen (Aarhus University, DK)"The structure of the tripartite E. coli HipBST toxin-antitoxin system reveals a novel mode of toxin inhibition"

Hot-spot talk 19 Sophie Howard (Imperial College London, UK)"The Pseudomonas aeruginosa type VI secretion system: a gun loaded with antimicrobial bullets"

Hot-spot talk 20 Susana Morcelle (National University of La Plata, AR)"Antibacterial activity of Nα-benzoyl-arginine-based surfactants and their possible mechanism of action"

@YMS2020Soton

[email protected]