Bimonthly Meeting on August 8, 2008
MRS study of Exam 4465 and Exam 3817
Amarjeet Bhullar
Exam ID: 4465June 23, 2008
Patient Name:
AD
I0.4
S9.6
S19.6
Exam ID: 3817Nov 29, 2007
I2.7
S7.3
S17.3
Choline Creatine NAA
Distribution of Metabolite Concentrations: Choline, Creatine and NAA
S19.6
0 7 14 21 28 35 42 490
2000
4000
6000
8000
10000
Inte
nsi
ty
Voxel Number
Choline
0 7 14 21 28 35 42 490
2000
4000
6000
8000
Voxel Number
Creatine
0 7 14 21 28 35 42 49
0
1x104
2x104
3x104
Voxel Number
NAA
0 7 14 21 28 35 42 490
2
4
Voxel Number
Computed FunctoolCho
Cre
0 7 14 21 28 35 42 49
0.0
0.5
1.0
1.5
Voxel Number
Computed FunctoolCho
NAA
Voxel Wise Distribution of Metabolites and Metabolite Ratios
Distribution of Metabolite Concentrations: Choline, Creatine and NAA
Choline Creatine NAA
S9.6
0 7 14 21 28 35 42 490
1000
2000
3000
Inte
nsi
ty
Voxel Number
Choline
0 7 14 21 28 35 42 490
1000
2000
3000
4000
Voxel Number
Creatine
0 7 14 21 28 35 42 490
2000
4000
6000
8000
10000
12000
Voxel Number
NAA
0 7 14 21 28 35 42 490.0
0.5
1.0
1.5
Voxel Number
Computed
FunctoolChoNAA
0 7 14 21 28 35 42 490
1
2
3
Voxel Number
Computed Functool
ChoCre
Voxel Wise Distribution of Metabolites and Metabolite Ratios
Choline Creatine NAA
Distribution of Metabolite Concentrations: Choline, Creatine and NAA
I0.4
0 7 14 21 28 35 42 490
2000
4000
6000
Inte
nsit
y
Voxel Number
Choline
0 7 14 21 28 35 42 490
2000
4000
6000
8000
Voxel Number
Creatine
0 7 14 21 28 35 42 490.0
5.0x103
1.0x104
1.5x104
2.0x104
2.5x104
Voxel Number
NAA
0 7 14 21 28 35 42 490
1
2
3
Voxel Number
Computed Functool
ChoCre
0 7 14 21 28 35 42 490
1
2
3
Voxel Number
Computed Functool
ChoNAA
Voxel Wise Distribution of Metabolites and Metabolite Ratios
Choline Creatine NAA
Cho/Cre Cho/NAA
Distribution of Metabolite Concentrations: Choline, Creatine and NAA
S7.3
0 30 60 90 120 150 180 210
0
1000
2000
3000
4000
5000
6000 Choline
Inte
nsi
ty
Voxel Number0 30 60 90 120 150 180 210
0
2000
4000
6000
Voxel Number
Creatine
0 30 60 90 120 150 180 210
0.0
5.0x104
1.0x105
1.5x105
2.0x105
2.5x105
Voxel Number
NAA
0 30 60 90 120 150 180 2100
2
4
Voxel Number
Computed Functool
ChoNAA
0 30 60 90 120 150 180 2100
2
4
Voxel Number
Computed Functool
ChoCre
Voxel Wise Distribution of Metabolites and Metabolite Ratios
Choline Creatine NAA
Cho/Cre Cho/NAA
Distribution of Metabolite Concentrations: Choline, Creatine and NAA
S17.3
Conclusion:
There is uncertainty between computed and Functool metabolite ratios.
Next Step:
Suggestions are welcome
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