The Study of Mandible Morphology towards Implant Design for the
South African Population
Presenter: Sven DelportCollaborator: Johan van der Merwe
IntroductionTechnimark:
• 1996
• Product development
– Concept
– Prototyping
– Testing
– Manufacturing
Introduction
Case Study
Morphology Study
Statistical Shape Modelling
Patient-specific Implant Design
Conclusion
1
Introduction
Energade Off-centre Nozzle Cap
Addis Comfi-Grip Range
Lawn Star Edge Trimmer
Introduction
Case Study
Morphology Study
Statistical Shape Modelling
Patient-specific Implant Design
Conclusion
2
IntroductionMedical Device Design:
• 2015
• Implant product development
• Patient-specific
– 3D anatomical models
– Implant design
Introduction
Case Study
Morphology Study
Statistical Shape Modelling
Patient-specific Implant Design
Conclusion
3
Case StudyIntroduction
Case Study
Morphology Study
Statistical Shape Modelling
Patient-specific Implant Design
Conclusion
• October 2015
• CRPM at the CUT
4
Case StudyIntroduction
Case Study
Morphology Study
Statistical Shape Modelling
Patient-specific Implant Design
Conclusion
5
Case StudyIntroduction
Case Study
Morphology Study
Statistical Shape Modelling
Patient-specific Implant Design
Conclusion
3-matic
• Symmetry did not work
• Mandible fitment
• Export point cloud
SolidWorks
• Parametric modelling
• Export STL
Surgeon
• Feedback
• Apply changes
6
Morphology Study• Bigger pictureIntroduction
Case Study
Morphology Study
Statistical Shape Modelling
Patient-specific Implant Design
Conclusion
Mandible Morphology
Study
Statistical Shape
Modelling
Patient-specific Implant Design
7
Co
Morphology Study• Morphology
– Study of form and structure
Introduction
Case Study
Morphology Study
Statistical Shape Modelling
Patient-specific Implant Design
Conclusion
*Reproduced from Bayome et al. (2013)
MSP
FHP
Med Co Lat Co
Go
FHP
Go
Co
Me
Sigmoid
8
Morphology Study• Compare statistical differences
– White, black, coloured (race)
– Male and female (gender)
• Left and right symmetry
– Paired t-test
• Correlation and relationship between variables
– Regression curves
Introduction
Case Study
Morphology Study
Statistical Shape Modelling
Patient-specific Implant Design
Conclusion
9
Statistical Shape Modelling• Model variation within a given set of
similar objects
• Train model on morphological data
– Estimate individual’s healthy or missing geometry from sparse input
• Validate model
– Use partial input not in training set
– Compare RMS error between actual and estimated
Introduction
Case Study
Morphology Study
Statistical Shape Modelling
Patient-specific Implant Design
Conclusion
10
Statistical Shape ModellingIntroduction
Case Study
Morphology Study
Statistical Shape Modelling
Patient-specific Implant Design
Conclusion
*Reproduced from Zachow et al. (2005)
Hypoplastic mandible Mean mandible
shape
Adaptation of shape model to healthy part of mandible
Template for implant design
11
Patient-specific Implant Design1. Take CT scan
2. Convert to 3D model
3. Apply SSM
4. Produce adapted 3D model
5. Design patient-specific implant
Introduction
Case Study
Morphology Study
Statistical Shape Modelling
Patient-specific Implant Design
Conclusion
12
Conclusion• Design of patient-specific mandibular
implants
– Statistically accurate
– Quick
– Unique to SA population
– Proudly South African
Introduction
Case Study
Morphology Study
Statistical Shape Modelling
Patient-specific Implant Design
Conclusion
13