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1
ROBB FRALEY, PH.D.CHIEF TECHNOLOGY OFFICER
GOLDMAN SACHS TENTH ANNUAL AGRICULTURAL BIOTECH FORUMFebruary 14, 2006
2
Forward-Looking Statements
Certain statements contained in this presentation are “forward-looking statements,” such as statements concerning the company’s anticipated financial results, current and future product performance, regulatory approvals, business and financial plans and other non-historical facts. These statements are based on current expectations and currently available information. However, since these statements are based on factors that involve risks and uncertainties, the company’s actual performance and results may differ materially from those described or implied by such forward-looking statements. Factors that could cause or contribute to such differences include, among others: continued competition in seeds, traits and agricultural chemicals; the company’s exposure to various contingencies, including those related to intellectual property protection, regulatory compliance and the speed with which approvals are received, and public acceptance of biotechnology products; the success of the company’s research and development activities; the outcomes of major lawsuits, including proceedings related to Solutia Inc.; developments related to foreign currencies and economies; successful completion and operation of recent and proposed acquisitions; fluctuations in commodity prices; compliance with regulations affecting our manufacturing; the accuracy of the company’s estimates related to distribution inventory levels; the company’s ability to fund its short-term financing needs and to obtain payment for the products that it sells; the effect of weather conditions, natural disasters and accidents on the agriculture business or the company’s facilities; and other risks and factors detailed in the company’s filings with the SEC. Undue reliance should not be placed on these forward-looking statements, which are current only as of the date of this release. The company disclaims any current intention or obligation to update any forward-looking statements or any of the factors that may affect actual results.
Trademarks
Roundup, Roundup Ready, Roundup Ready2Yield, Bollgard, Bollgard II, YieldGard, Monsanto, Imagine, Vine Design, Asgrow, DEKALB, Monsanto Choice Genetics, Posilac, Processor Preferred, and Vistive are trademarks owned by Monsanto Company and its wholly-owned subsidiaries and are italicized the first time they appear in this presentation. Mavera™ is a trademark of Renessen.
3
Non-GAAP Financial Information
This presentation may use the non-GAAP financial measures of “free cash flow,” earnings per share (EPS) on an ongoing basis, and Return on Capital (ROC). We define free cash flow as the total of cash flows from operating activities and investing activities. A non-GAAP EPS financial measure, which we refer to as on-going EPS, excludes certain after-tax items that we do not consider part of ongoing operations, which are identified in the reconciliation. ROC means net income (without the effect of certain items) exclusive of after-tax interest expenses, divided by the average of the beginning year and ending year net capital employed, as defined in the reconciliation. Our presentation of non-GAAP financial measures is intended to supplement investors’ understanding of our operating performance. These non-GAAP financial measures are not intended to replace net income (loss), cash flows, financial position, or comprehensive income (loss), as determined in accordance with accounting principles generally accepted in the United States. Furthermore, these non-GAAP financial measures may not be comparable to similar measures used by other companies. The non-GAAP financial measures used in this presentation are reconciled to the most directly comparable financial measures calculated and presented in accordance with GAAP, which can be found at the end of this presentation.
Fiscal Year
In this presentation, unless otherwise specified, references to Monsanto’s fiscal years refer to the 12-month period ending August 31.
Trademarks
Roundup, Roundup Ready, Roundup Ready2Yield, Bollgard, Bollgard II, YieldGard, Monsanto, Imagine, Vine Design, Asgrow, DEKALB, Monsanto Choice Genetics, Posilac, Processor Preferred, Vistive, and French Kiss are trademarks owned by Monsanto Company and its wholly-owned subsidiaries and are italicized the first time they appear in this presentation.
Mavera™ is a trademark of Renessen.
4
OVERVIEW
Breeding and Biotech Provide Parallel R&D Paths to Commercial Products
PHASE II PHASE III PHASE IVPHASE IDISCOVERY LAUNCH
BREEDING and BIOTECHNOLOGY form two R&D pathways
Separate, but parallel, the BREEDING and BIOTECHNOLOGY pathways are linked by shared tools.
ELI
TE
G
ER
MP
LAS
M
GE
NO
MIC
S
MA
RK
ER
S
ITP
LAT
FOR
M
AN
ALY
TIC
S
CO
MM
ER
CIA
L
BREEDING
BIOTECHNOLOGY
Germplasm
RSEED SOLD TO FARMERS
R&D PHASE:
5
OVERVIEW
Combination of Predictable Progress and Early-Phase Additions Created Milestone Year Across Pipeline
FIELD TESTING
July
Augu
stS
epte
mbe
r
December
January November
Febr
uary
Mar
ch
June
May
April
October
DATA COLLECTION
DATA ANALYSIS
PORTFOLIO UPDATE
PRIORITY UPDATE
ANNUAL R&D CYCLE: SEEDS & TRAITS
Strong breeding base in place, currently working on targets across farmer, processor and consumer segments, as well as converting open-pollinated crops
SEMINIS BREEDING
Breeding effort strengthens Stoneville’s offerings and enables entrance of Cotton States into cotton germplasm market
COTTON BREEDING
First-generation molecular breeding varieties showed better yield results than current competitive commercial set in field trials
SOYBEAN BREEDING
Field trial yield differentials versus competitors even greater than in 2004CORN BREEDING
BREEDING PIPELINE
Ten projects were added to Phase I or later as a result of Discovery work or collaborative partnerships
PIPELINE ADDITIONS
Fifteen projects either advanced from one phase to another or were added to the pipeline, representing positive movement in >50% of current pipeline projects
PIPELINE PROGRESS
BIOTECH TRAIT PIPELINE
2005 PERFORMANCE
R&D PIPELINE SCORECARDKEY METRICS MEASURING PIPELINE PROGRESS
6
KEY MARKET ACRES
AVAILABLE MARKET
PERCENT PENETRATED
ASI BRAZIL ARGENTINA80M 30M 6M
3% 35% 49%
LICENSEDBRANDU.S.
32%16%
Corn breeding
PIPELINE UPDATE
Corn Germplasm Improvements Are Tightly Linked to Market Share Gains
CREATING VALUE
2006 FOCUS
• Continue marker-based breeding approach• Continue focus on broadening genetic base of
commercial products, including strengthening our international portfolio
• On pace to gain market share in U.S. corn seed for fifth consecutive year
• Average yield differential of Monsanto versus competitors’ best material is better than one-third greater in 2005 compared with 2004 testing
• Strong yield advantages are consistent across maturity zones and outperform best competitive commercial material sold in 2005
Corn Breeding
2005 PERFORMANCE
PROJECT UPDATE
RE
SU
LTS
RE
SU
LTS
150
160
170
180
190
200
95 100 105 110 115RELATIVE MATURITIES (DAYS)
2005 CORN YIELD (BU/A) MONSANTO BRANDS
COMPETITORS
85
90
95
100
105
110
115
120
SE
LEC
TIO
N I
ND
EX
MONSANTO COMMERCIAL
LEADERS
MONSANTO NEW 2006 HYBRIDS
OTHER MONSANTO PIPELINE HYBRIDS
COMPETITIVE HYBRID
LEADERS
CORN PIPELINE HYBRID PERFORMANCE (110 RM)
7
KEY MARKET ACRES
AVAILABLE MARKET
PERCENT PENETRATED
14M
COTTON STATESSTONEVILLE
U.S.
0%14%
Cotton breeding
PIPELINE UPDATE
Cotton Breeding Program Provides Rich Source of Germplasm to Branded and Licensed Businesses
CREATING VALUE
2006 FOCUS
• Introduce 4-6 new, improved varieties with latest trait offerings
• Continue marker-based breeding approach• Expand breeding program and evaluations of additional
varieties
• Monsanto varieties competitive with current market leaders and include Roundup Ready Flex stacked with Bollgard II
• Stoneville will offer 9 varieties either with the Roundup Ready Flex trait or with Roundup Ready Flex stacked with Bollgard II
• Cotton States will have 5 licensees in 2006
Cotton Breeding
2005 PERFORMANCE
PROJECT UPDATE
RE
SU
LTS
0
200
400
600
800
1000
1200
1400
1600
LBS
LIN
T/A
CR
E
MONSANTO VARIETIES
2005 COMPETITIVE
LEADERS
2005 COTTON GERMPLASM PERFORMANCE(19 LOCATIONS)
8
Seminis Addition to Monsanto Quickly Contributes to Growth And Opens New Business and Research Opportunities
1Market Position
NORTH AMERICA
2005
34%Market Share
1Market Position
EUROPE-AFRICA
2005
19%Market Share
3Market Position
ASIA-PACIFIC
2005
7%Market Share
1Market Position
SOUTH AMERICA
2005
37%Market Share
OPPORTUNITYFruit & vegetable seeds only represent approximate farmgate value (corn: 13.2%; soybeans: 11.4%)Significant growth opportunities in hybrid creationSeminis has the largest global vegetable germplasm library; molecular breeding tools honed in row crops will be applied to vegetables
COMMERCIAL OPPORTUNITY
9
LEADERSHIP
Efficient Discovery Program Is in Full Gear, Fueling Pipeline Expansion and Performance
1<510sTHOUSANDSTENS OF THOUSANDSGENES IN TESTING
•REGULATORY SUBMISSION
•SEED BULK-UP•PRE-MARKETING
•TRAIT INTEGRATION•FIELD TESTING•REGULATORY DATA GENERATION
•TRAIT DEVELOPMENT
•PRE-REGULATORY DATA
•LARGE-SCALE TRANSFORMATION
•GENE OPTIMIZATION•CROP TRANSFORMATION
•HIGH-THROUGHPUT SCREENING
•MODEL CROP TESTING
KEY ACTIVITY
90 PERCENT75 PERCENT50 PERCENT25 PERCENT5 PERCENTAVERAGE PROBABILITY OF SUCCESS2
12 to 36 MONTHS12 to 24 MONTHS12 to 24 MONTHS12 to 24 MONTHS24 to 48 MONTHSAVERAGE DURATION1
PHASE IVPre-launch
PHASE IIIAdvanced Development
PHASE IIEarly Development
PHASE IProof Of Concept
DISCOVERYGene/Trait Identification
MONSANTO DISCOVERY + COLLABORATIVE PARTNERS
KEY INFLECTON POINT:AFTER PHASE II COMMERCIAL SUCCESS GOES TO >50% WITH LEADS ON COMMERCIAL TRACK
1. Time estimates are based on our experience; they can overlap. Total development time for any particular product may be shorter or longer than the time estimated here.2. This is the estimated average probability that the traits will ultimately become commercial products, based on our experience. These probabilities may change over time.
TRAIT INTEGRATION
FIELD TESTING
REGULATORY DATA GENERATIONREGULATORY SUBMISSIONSEED BULK UP
10
LEADERSHIP
Monsanto Is Upgrading the Entire Commercial Trait Portfolio to Second- and Third-Generation Traits
CORE FIRST-GENERATION TECHNOLOGY
YIELDGARD CORN BORER (1997)
BENEFIT: FULL-SEASON CONTROL OF EUROPEAN CORN BORER
2ND GEN YIELDGARD CORN BORER
UPGRADE: BROADER INSECT CONTROL; BETTER IRM PROPERTIES
COMMERCIALIZED SECOND-GENERATION
ROUNDUP READYCORN (1998)
BENEFIT: NEW WEED CONTROL SYSTEM
ROUNDUP READYCORN 2(2001)
UPGRADE: SIMPLIFIED WEED CONTROL, GREATER FLEXIBILITY
YIELDGARD ROOTWORM
(2003)
BENEFIT: CONTROL OF CORN ROOTWORM
2ND GEN YIELDGARD ROOTWORM
UPGRADE: IMPROVED EFFICIENCY OF STACKING IN ELITE GERMPLASM
TECHNOLOGY UPGRADES IN THE PIPELINE
ROUNDUP READYSOYBEANS
(1996)
BENEFIT: NEW WEED CONTROL SYSTEM
ROUNDUP RREADY2YIELD
SOYBEANS
UPGRADE: GREATER FLEXIBILITY; YIELD BENEFIT
DICAMBA-TOLERANT SOYBEANS
UPGRADE: ADDITIONAL MODE OF ACTION
BOLLGARD COTTON (1996)
BENEFIT: IN-PLANT CONTROL OF THE BOLLWORM
BOLLGARD IICOTTON (2003)
BENEFIT: BROADER INSECT CONTROL; BETTER IRM PROPERTIES
BOLLGARD IIICOTTON
BENEFIT: BROADER INSECT CONTROL; BETTER IRM PROPERTIES
ROUNDUP READYCOTTON (1997)
BENEFIT: NEW WEED CONTROL SYSTEM
ROUNDUP READYFLEX COTTON
(2006)
BENEFIT: GREATER FLEXIBILITY; HERBICIDE REPLACEMENT
DICAMBA-TOLERANT COTTON
BENEFIT: ADDITIONAL MODE OF ACTION
PHASE IVPre-launch
PHASE IIIAdvanced Development
PHASE IIEarly Development
PHASE IProof Of Concept
DISCOVERYGene/Trait Identification
YIELDGARD ROOTWORM II
UPGRADE: NEW MODE OF ACTION FOR INSECT CONTROL
11
KEY MARKET ACRES
AVAILABLE MARKET
PERCENT PENETRATED
U.S. INDIA
10-15M 10-15M
0% 0%
DISCOVERY PHASE IProof of Concept
PHASE IIEarly Development
PHASE IIIAdv. Development
PHASE IVPre-Launch
LAUNCH
Roundup ReadyFlex Cotton
Roundup Ready Flex Launch To Be Most Significant in 10-Year History of Biotech Traits
• Pricing at a premium of $6-$11 an acre over the first-generation of Roundup Readycotton
LEADERSHIP
2006 STATUS
ROUNDUP READY FLEX COTTON
(2006)
The Roundup ReadyFlex cotton trait will be coupled with our
Stoneville brand and our Cotton States
licensing as a showcase of
Monsanto’s cotton business
Anticipated trait launch of 2-3 million acres in U.S. in 2006 through 10 cotton seed suppliers
Roundup Ready Flex will be only stacked with Bollgard II at approximately 70-80% of mix
Introductory acres planted in Australia; full launch set for 2007
Trait in initial breeding phase with licensees in India in preparation for filing for regulatory field trials
AUSTRALIA
0.5-0.8M
0%
12
LEADERSHIP
Within Discovery Platforms, Products Are Maturing into Families
TECHNOLOGY UPGRADES IN THE PIPELINE
ROUNDUP READY CORN (1998)
ROUNDUP READY SOYBEANS
(1996)
ROUNDUP READY COTTON (1997)
FIRST-GENERATION TECHNOLOGY
COMMERCIALIZED SECOND-GENERATION
ROUNDUP RREADY2YIELD
SOYBEANS
DICAMBA-TOLERANT SOYBEANS
ROUNDUP READY FLEX COTTON
(2006)
DICAMBA-TOLERANT COTTON
ROUNDUP READY CORN 2(2001)
DROUGHT-TOLERANT COTTON
2nd GEN DROUGHT-
TOLERANT CORN
DROUGHT-TOLERANT CORN
DROUGHT-TOLERANT SOYBEANS
HERBICIDE TOLERANCE
STRESS TOLERANCE
GRAIN YIELD
HIGHER-YIELDING CORN
NITROGEN-UTILIZATION
CORN
HIGHER-YIELDING SOYBEANS
HEALTHIER FOODS
VISTIVE LOW LIN SOYBEANS
VISTIVE II LOW LIN - MID OLEIC
SOYBEANS
VISTIVE III LOW LIN - MID OLEIC –
LOW SAT SOYBEANS
12
12
23
23
12
12
1
1
1
1
1
12 23
PHASE IVPre-launch
PHASE IIIAdvanced Development
PHASE IIEarly Development
PHASE IProof Of Concept
DISCOVERYGene/Trait Identification
OMEGA-3 SOYBEANS
IMPROVED-PROTEIN SOYBEANS
13
LEADERSHIP
Weed Control Family Is Progressing Fastest on Multi-Generational, Multi-Crop Offerings
TECHNOLOGY UPGRADES IN THE PIPELINE
ROUNDUP READY CORN (1998)
ROUNDUP READY SOYBEANS
(1996)
ROUNDUP READY COTTON (1997)
FIRST-GENERATION TECHNOLOGY
COMMERCIALIZED SECOND-GENERATION
ROUNDUP RREADY2YIELD
SOYBEANS
DICAMBA-TOLERANT SOYBEANS
ROUNDUP READY FLEX COTTON
(2006)
DICAMBA-TOLERANT COTTON
ROUNDUP READY CORN 2(2001)
HERBICIDE TOLERANCE
12
12
23
23
12
PHASE IVPre-launch
PHASE IIIAdvanced Development
PHASE IIEarly Development
PHASE IProof Of Concept
DISCOVERYGene/Trait Identification
Herbicide Tolerance Family
• First-mover advantage has enabled development of family of products and extension into multiple crops
• Expansion possible because of strength of internal discovery program and licensing relationships
• Pricing on next-generation traits reflects flexibility in weed control, yield gains and other benefits that accrue to the farmer
14
KEY MARKET ACRES
AVAILABLE MARKET
PERCENT PENETRATED
U.S. BRAZIL ARGENTINA
70M 50M 35M
0% 0% 0%
DISCOVERY PHASE IProof of Concept
PHASE IIEarly Development
PHASE IIIAdv. Development
PHASE IVPre-Launch
LAUNCH
Roundup RReady2Yieldsoybeans
PIPELINE UPDATE
Second-Generation Platform Expands Soybean Weed Control Window, Benefits for Growers
CREATING VALUE
PHASE IVPHASE IIDISCOVERY
2006 FOCUS
• Continued field testing to build data for regulatory submissions
• Continued field testing to confirm glyphosate activity in suppressing Asian rust in soybeans
PHASE IIIPHASE I
• Lead event confirmed in April of 2005• 2005 U.S. field trials confirmed target yield and wider
window of application benefits• Trait integration efforts started• Implementation of marker-assisted selection
Roundup RReady2Yield soybeans
2005 PERFORMANCE
PROJECT UPDATE
2005 U.S. field tests confirmed yield targets; The use of marker-assisted selection helped teams working on trait selection
RE
SU
LTS
15
KEY MARKET ACRES
AVAILABLE MARKET
PERCENT PENETRATED
U.S. BRAZIL ARGENTINA
70M 50M 35M
0% 0% 0%
DISCOVERY PHASE IProof of Concept
PHASE IIEarly Development
PHASE IIIAdv. Development
PHASE IVPre-Launch
LAUNCH
Dicamba-tolerant soybeans
PIPELINE UPDATE
Third-Generation of Soy Weed Control Encouraging in 2005 Field Trials
CREATING VALUE
PHASE IVPHASE IIDISCOVERY
2006 FOCUS
• Continue to screen events in field conditions, screening for leads with commercial potential
PHASE IIIPHASE I
• Third-generation project enters pipeline in Phase II as a result of University of Nebraska collaboration announced in 2005
• Predicted value added in the range of $2.50-$12/acre, depending on the weed spectrum
Dicamba-tolerant soybeans
2005 PERFORMANCE
PROJECT UPDATE
Tolerance demonstrated at both pre-emergence and post-emergence application timing, with no visual crop injury at rates of 1.5lb/acre, which is three times the labeled use rate (above)
RE
SU
LTS
WITHOUT TRAIT
WITH TRAIT
16
LEADERSHIP
Stress Family Has Already Entered Second-Generation Discovery, Expanded Into New Crops
TECHNOLOGY UPGRADES IN THE PIPELINE FIRST-GENERATION TECHNOLOGY
COMMERCIALIZED SECOND-GENERATION
DROUGHT-TOLERANT COTTON
2nd GEN DROUGHT-
TOLERANT CORN
DROUGHT-TOLERANT CORN
DROUGHT-TOLERANT SOYBEANS
STRESS TOLERANCE
12
1
1
PHASE IVPre-launch
PHASE IIIAdvanced Development
PHASE IIEarly Development
PHASE IProof Of Concept
DISCOVERYGene/Trait Identification
Stress Tolerance Family
• Initial discovery focus on drought tolerance
• Rapid pace of discovery has led to second-generation corn trait entering Phase I as first-generation advances to Phase II
• Expansion already made into multiple crops
17
KEY MARKET ACRES
AVAILABLE MARKET
PERCENT PENETRATED
U.S. BRAZIL ARGENTINA
80M 30M 6M
0% 0% 0%
DISCOVERY PHASE IProof of Concept
PHASE IIEarly Development
PHASE IIIAdv. Development
PHASE IVPre-Launch
LAUNCH
Drought-tolerant corn
PIPELINE UPDATE
Drought-Tolerant Corn Advances to Phase II Based on Second-Year Field Test Results
CREATING VALUE
PHASE IVPHASE IIDISCOVERY
2006 FOCUS
• Continue to screen lead events for performance • Continue commercial transformations for second
generation of drought tolerance; Second set of genes are being evaluated in Discovery and Phase I
• Select optimal germplasm for drought genes
PHASE IIIPHASE I
• Moved into Phase II• In second year, lead genes tested in drought conditions
in 7 locations, broad-acre application in 10 locations• Physiological drought tolerance repeated over past 3
years
Drought-tolerant corn
2005 PERFORMANCE
PROJECT UPDATE
-40
-20
0
20
40
60 80 100 120
LOCATIONS WITH INCREASING DROUGHT SEVERITY
% Y
IELD
AD
VA
NT
AG
E
In multiple locations of drought-condition field trials, best-performing events show significant yield advantage over conventional checks
Drought tolerance established through plant physiology (performance) over three years
RE
SU
LTS
RE
SU
LTS
2
4
6
8
2003 2004 2005% I
MP
RO
VE
D G
RO
WT
H
DU
RIN
G D
RO
UG
HT
ST
RE
SS
18
KEY MARKET ACRES
AVAILABLE MARKET
PERCENT PENETRATED
U.S. AUSTRALIA
7M 0.5M
0% 0%
DISCOVERY PHASE IProof of Concept
PHASE IIEarly Development
PHASE IIIAdv. Development
PHASE IVPre-Launch
LAUNCH
Drought-Tolerant Cotton
PIPELINE UPDATE
Drought-Tolerant Cotton Performance Encouraging in Early Field Evaluation
CREATING VALUE
FROM GREENHOUSE TESTING TO….
…FIRST YEAR FIELD
TRIALS
DROUGHT-TOLERANTCONTROL
DROUGHT-TOLERANTCONTROL
PHASE IVPHASE IIDISCOVERY
2006 FOCUS
• Continue to evaluate to assess drought performance
PHASE IIIPHASE I
• Drought leads are working across crops• First leads into cotton are showing promise
Drought-tolerant cotton
2005 PERFORMANCE
PROJECT UPDATE
19
LEADERSHIP
Yield Family Expanding in Corn and Soy with Multiple Approaches to Enhancing Intrinsic Yield
TECHNOLOGY UPGRADES IN THE PIPELINE FIRST-GENERATION TECHNOLOGY
COMMERCIALIZED SECOND-GENERATION
GRAIN YIELD
HIGHER-YIELDING CORN
NITROGEN-UTILIZATION
CORN
HIGHER-YIELDING SOYBEANS
1
1
1
PHASE IVPre-launch
PHASE IIIAdvanced Development
PHASE IIEarly Development
PHASE IProof Of Concept
DISCOVERYGene/Trait Identification
Grain Yield Family
• Objective is to maximize intrinsic yield of germplasm
• Nitrogen utilization in corn is lead product in the family
20
KEY MARKET ACRES
AVAILABLE MARKET
PERCENT PENETRATED
U.S. BRAZIL ARGENTINA
80M 30M 6M
0% 0% 0%
DISCOVERY PHASE IProof of Concept
PHASE IIEarly Development
PHASE IIIAdv. Development
PHASE IVPre-Launch
LAUNCH
Nitrogen utilization corn
PIPELINE UPDATE
Nitrogen Utilization Corn Emerged from Discovery Engine to First-Year Field Testing
CREATING VALUE
PHASE IVPHASE IIDISCOVERY
2006 FOCUS
• Enhanced nitrogen utilization is a challenging trait, so industrial scale genomics is continuing to identify more leads
• Continue to refine the gene constructs for optimal performance
PHASE IIIPHASE I
• Emerged from Discovery to Phase I field testing • Lead events show roughly 10 percent increase in yield
in multi-location field trials
Nitrogen utilization corn
2005 PERFORMANCE
PROJECT UPDATE
At standard nitrogen rates (120 lbs/ac) there is yield advantage over conventional check
Broad screens of hundreds of traits in low, medium and high nitrogen situations allow us to identify candidates for more intensive field testing
RE
SU
LTS
RE
SU
LTS
LOW N MED N HIGH N
Genes
POUNDS OF N APPLIED/ACRE
YIE
LD (
BU
/AC
RE
)
110
130
150
170
190
0 50 100 150 200
CONTROL
EVENT 1EVENT 2
21
KEY MARKET ACRES
AVAILABLE MARKET
PERCENT PENETRATED
U.S. BRAZIL ARGENTINA
80M 50M 35M
0% 0% 0%
DISCOVERY PHASE IProof of Concept
PHASE IIEarly Development
PHASE IIIAdv. Development
PHASE IVPre-Launch
LAUNCH
Higher-yielding soybeans
PIPELINE UPDATE
Higher-Yielding Soybeans Showing Good Results in Second-Year Field Tests
CREATING VALUE
PHASE IVPHASE IIDISCOVERY
2006 FOCUS
• Initiate commercial transformations and optimization to improve trait performance
PHASE IIIPHASE I
• Advanced to Phase II• Tested hundreds of events in both first- and second-
year field testing over approximately 20 locations• Volume of current events in testing as a result of
partnership with Mendel
Higher-yielding soybeans
2005 PERFORMANCE
PROJECT UPDATE
Yield advantage over conventional checks improved in leads in second-year testing
Higher yield potential is being validated in field environment versus conventional checks, with visible plant height differences
RE
SU
LTS
RE
SU
LTS
0
2
4
6
8
10
Event 1 Event 2 Event 3
20042005
YIE
LD A
DV
AN
TA
GE
(% O
F C
ON
TR
OL)
CONTROL
WITH TRAIT
22
LEADERSHIP
Pipeline and Commercial Prospects Are Strong, Diverse Across Food-Trait Platforms
TECHNOLOGY UPGRADES IN THE PIPELINE FIRST-GENERATION TECHNOLOGY
COMMERCIALIZED SECOND-GENERATION
HEALTHIER FOODS
VISTIVE LOW LIN SOYBEANS
VISTIVE II LOW LIN - MID OLEIC
SOYBEANS
VISTIVE III LOW LIN - MID OLEIC –
LOW SAT SOYBEANS
12 23
PHASE IVPre-launch
PHASE IIIAdvanced Development
PHASE IIEarly Development
PHASE IProof Of Concept
DISCOVERYGene/Trait Identification
OMEGA-3 SOYBEANS
IMPROVED-PROTEIN SOYBEANS
Healthier Foods Family
• Vistive low-linolenic soybeans to expand to 500,000 acres in 2006
• Agreement signed with SolaeCompany to use improved-protein soybeans in a new product line
• Positive progress made across the family, including Omega-3 soybeans advancing phases
23
KEY MARKET ACRES
AVAILABLE MARKET
PERCENT PENETRATED
U.S. BRAZIL ARGENTINA
TBD TBD TBD
0% 0% 0%
DISCOVERY PHASE IProof of Concept
PHASE IIEarly Development
PHASE IIIAdv. Development
PHASE IVPre-Launch
LAUNCH
Omega-3 soybeans
PIPELINE UPDATE
2005 Marked Successful Completion of Initial Taste, Smell and Oil Stability Testing for Omega-3 Soybeans
CREATING VALUE
PHASE IVPHASE IIDISCOVERY
2006 FOCUS
• Continue to screen to select the lead event for regulatory submission
PHASE IIIPHASE I
• Moved into Phase III• Field trials continue to confirm expression of
stearidonic acid (SDA) levels at concept targets• Initial sensory data superior to fish oil
Omega-3 soybeans
2005 PERFORMANCE
PROJECT UPDATE
In testing for oil stability, SDA oil produced from Omega-3 soybean plants showed less oxidation – an indicator of stability – than fish oil where both oils were stabilized with commercial products
RE
SU
LTS
20% SDA w/ CA
0
50
100
150
200
250
300
350
400
0 2 4 6 8 10 12 14 16 18 20 22 24 26 28 30DAYS AT 55°C
PE
RO
XID
E V
ALU
E, M
EQ
/KG Stabilized Fish Oil
Stabilized 20% SDA
24
Bollgard III
2nd-Gen Drought-tolerant corn
2006 Pipeline AS OF JANUARY 1, 2006
OVERVIEW
YieldGard Rootworm II
Dicamba-tolerant soybeans
Omega-3 soybeans
Vistive III Low Lin – Mid Oleic – Low Sat soybeans
Vistive II Low Lin – Mid Oleic soybeans
Improved-protein soybeans
High oil soybeans for processing
Feed Corn with balanced proteins
2nd-Gen High-value corn with lysine
Mavera™ II High-value soybeans
Mavera™ I High-value soybeans
Mavera™ High-value corn with lysine
PHASE IVPre-launch
PHASE IIIAdvanced Development
PHASE IIEarly Development
PHASE IProof Of Concept
DISCOVERYGene/Trait Identification
Drought-tolerant corn
Insect-protected soybeans
Soybean nematode-resistance
Higher-yielding canola
Roundup RReady2Yield canola
Roundup RReady2Yield soybeans
Higher-yielding soybeans
Nitrogen utilization corn
Higher-yielding corn
Drought-tolerant cotton
Drought-tolerant soybeans
2nd-Gen YieldGard Corn Borer
2nd-Gen YieldGard Rootworm
Dicamba-tolerant cotton
Roundup Ready Flex cotton
FAR
ME
RP
RO
CE
SS
OR
CO
NS
UM
ER
25
LEADERSHIP
Monsanto’s Pipeline Is Balanced Across Multiple Market Opportunities
TOTAL ACRE OPPORTUNITY1
RE
TA
IL V
ALU
E P
ER
AC
RE
2
SMALL: <5M ACRES MEDIUM: <20M ACRES HIGH: >20M ACRES
SM
ALL
: <$
10/ A
CR
EM
ED
IUM
: <$
30/ A
CR
EH
IGH
: >$
30/ A
CR
E
1. “Total Acre Opportunity” represents the maximum acre penetration by the trait individually and as a stacked trait during the three-year span of its peak; Second- and third-generation traits may cannibalize acre opportunities of preceding product offerings
2. “Retail Value Per Acre” represents the per-acre average value for the individual trait in the three-year span during the trait penetration peak
ROUNDUP READYFLEX COTTON
ROUNDUP RREADY2YIELDSOYBEANS
ROUNDUP RREADY2YIELDCANOLA
DICAMBA-TOLERANT SOYBEANS
DICAMBA-TOLERANT COTTON
2ND GEN YIELDGARDROOTWORM2ND GEN YIELDGARD CORN BORER
INSECT-PROTECTED SOYBEANS
YIELDGARDROOTWORM II
SOYBEAN NEMATODE RESISTANCE
BOLLGARD III
DROUGHT-TOLERANT CORN
HIGHER-YIELDING CANOLA
DROUGHT-TOLERANT SOYBEANS
DROUGHT-TOLERANT COTTON
NITROGEN-UTILIZATION CORN
HIGHER-YIELDING SOYBEANS
MAVERATM HIGH-VALUE CORN WITH LYSINE
MAVERATM HIGH-VALUE SOYBEANS
MAVERATM II HIGH-VALUE SOYBEANS
2ND GEN HIGH-VALUE CORN WITH LYSINE
FEED CORN WITH BALANCED PROTEINS
HIGH OIL SOYBEANS FOR PROCESSING
IMPROVED-PROTEIN SOYBEANS
VISTIVE II SOYBEANS
VISTIVE III SOYBEANS
OMEGA 3 SOYBEANS
26
90% penetration80-85% penetration
AUSTRALIA COTTON TRAITS
KEY COMMERCIAL COMMITMENTS
1 – 2pts1 – 2 ptsUS CORN SHARE
5 – 10 cents per share
2 – 3M ACRES
1 – 2 POINTS
10M ACRES
34M ACRES
$825M - $900M
$2.35-$2.50 TOWARD UPPER END OF RANGE
2006 FORECAST
5 – 10 cents per share
BRAZIL RR EPS
$875-$950M
$2.82-$3.00 20% GROWTH
FROM 2006 PROJECTION
2007COMMITMENT
2006 COMMITMENT
2 – 3M ACRESUS RR FLEX
1 – 2 POINTSUS COTTON SHARE
8M ACRESUS YGRW
$825M - $900M
30M ACRESUS RR CORN
FREE CASH FLOW
EARNINGS PER SHARE
$2.35-$2.50 UP TO 20%
GROWTH FROM 2005
FY2006 AND FY2007 TARGETS FY2008 - FY2010
LEADERSHIP
Accelerate Current Commercial Platform
Expanded long–term opportunity for corn traits, reflecting opportunity in licensing, stacking and price-to-value strategies
Expand in New MarketsPenetration of new markets in Asia, Europe and South America with existing traits
New opportunity in the high-margin Seminis business
Discover New Opportunities Through Research
Refreshing of first-generation trait portfolio
Breeding programs expand our genetic footprint
Translate Growth to ValueGross profit mix reflects higher-margin seeds and traits
Drivers of Growth in Mid-Term and Long-Term Horizons Are On Track
OVERVIEW
27
Reconciliation of Non-GAAP Financial Measures
Reconciliation of Free Cash Flow
N/A
N/A
$825 - $900
$(475)
$1,300 - $1,375
Fiscal Year2006
Target
N/ANet Increase in Cash and Cash Equivalents
N/ANet Cash Provided (Required) by Financing Activities
$875-$950Free Cash Flow
$(500)Net Cash Provided (Required) by Investing Activities
$1,375 - $1,450Net Cash Provided by Operations
Fiscal Year 2007
Target$ Millions