Embed Size (px)
Citation preview
Biochemistry & Biomolecules
International Journal of
IJBBJul–Dec 2016
www.journalspub.com
Mechanical Engineering
Electronics and Telecommunication Chemical Engineering
Architecture
Office No-4, 1 Floor, CSC, Pocket-E,Mayur Vihar, Phase-2, New Delhi-110091, India
E-mail: [email protected]
¬ International Journal of Thermal Energy andApplications
¬ International Journal of Production Engineering¬ International Journal of Industrial Engineering
and Design¬ International Journal of Manufacturing and
Materials Processing¬ International Journal of Mechanical Handling and
Automation
« International Journal of Radio Frequency Design« International Journal of VLSI Design and Technology« International Journal of Embedded Systems and Emerging
Technologies« International Journal of Digital Electronics« International Journal of Digital Communication and Analog
Signals
« International Journal of Housing and Human SettlementPlanning
« International Journal of Architecture and InfrastructurePlanning
« International Journal of Rural and Regional PlanningDevelopment
« International Journal of Town Planning and Management
Applied Mechanics
5 more...
1 more...
2 more...2 more...
5 more...
Computer Science and Engineering « International Journal of Wireless Network Security« International Journal of Algorithms Design and Analysis« International Journal of Mobile Computing Devices« International Journal of Software Computing and Testing« International Journal of Data Structures and Algorithms
Nanotechnology« International Journal of Applied Nanotechnology« International Journal of Nanomaterials and Nanostructures« International Journals of Nanobiotechnology
« International Journal of Solid State Materials« International Journal of Optical Sciences
Physics
« International Journal of Renewable Energy and itsCommercialization
« International Journal of Environmental Chemistry« International Journal of Agrochemistry« International Journal of Prevention and Control of Industrial
Pollution
Civil Engineering« International Journal of Water Resources Engineering« International Journal of Concrete Technology« International Journal of Structural Engineering and Analysis« International Journal of Construction Engineering and
Planning
Electrical Engineering« International Journal of Analog Integrated Circuits« International Journal of Automatic Control System« International Journal of Electrical Machines & Drives« International Journal of Electrical Communication
Engineering« International Journal of Integrated Electronics Systems and
Circuits
Material Sciences and Engineering « International Journal of Energetic Materials« International Journal of Bionics and Bio-Materials« International Journal of Ceramics and Ceramic Technology« International Journal of Bio-Materials and Biomedical
Engineering
Chemistry « International Journal of Photochemistry« International Journal of Analytical and Applied Chemistry« International Journal of Green Chemistry« International Journal of Chemical and Molecular
Engineering
« International Journal of Electro Mechanics andMechanical Behaviour
« International Journal of Machine Design andManufacturing
« International Journal of Mechanical Dynamicsand Analysis
« International Journal of Fracture and damageMechanics
« International Journal of Structural Mechanicsand Finite Elements
5 more...4 more...
3 more...
Biotechnology « International Journal of Industrial Biotechnology and
Biomaterials« International Journal of Plant Biotechnology« International Journal of Molecular Biotechnology« International Journal of Biochemistry and Biomolecules« International Journal of Animal Biotechnology and
Applications3 more...
Nursing « International Journal of Immunological Nursing« International Journal of Cardiovascular Nursing« International Journal of Neurological Nursing« International Journal of Orthopedic Nursing« International Journal of Oncological Nursing
5 more... 4 more...
Subm
it
Your
Article 2
017
International Journals Publisher
JournalsPub is a multi-disciplinary international journal boosting innovative & eminence research work
by Division of Dhruv Infosystems Pvt. Ltd. Launched in 2014 under the support and guidance by our
Honorable Editorial Board Members from renowned institutes.
Objectives of JournalsPub
JournalsPub is international scholarly journal that publishes peer reviewed journal in the frontier areas of
Applied Sciences, Medical and Engineering.
JournalsPub publishes Original Research Papers, Review Papers, Popular Articles, Short
Communications & Case Study.
Publishing special issues on Proceedings of Conferences, Seminars and Symposia.
JournalsPub Publishes issues twice a year (bi-annually) in English-language which is available online
(open access) and in printed version with a goal to promote an extensive academic awareness.
JournalsPub desires to set a good benchmark in the publishing industry by launching more than 100+
new International Journals to help the scientific community to enhance communication within the
research communities and maintain a balance between the existing and emerging interdisciplinary
technologies.
JournalsPub aims to provide quality research articles for Academic Researchers, Industrial
Professionals, Engineers, Scientists, Professors, etc. working in the areas of Applied Sciences, Medical
and Engineering to contribute and communicate innovative work.
Salient Features
An umbrella of 100+ journals that covers Applied Sciences, Medial and Engineering Arena.
The first and one of the rapidly emerging publication website in Country as well as overseas for its
excellence and exposure.
Universal transmission and reflectivity.
A Rigorous, Fast and Constructive Peer Review Process
Speedy Publication of Manuscripts
Eminent Editorial Board Members from renowned organizations.
Free Registration, Online Submission, Processing, Publication & Online Access of Manuscripts.
The journal publishes novel research articles with emphasis on theoretical and experimental work.
International Journal of
Biochemistry and Biomolecules
JournalsPub (Division of Dhruv Infosystems Private Ltd.) having its Marketing office located at Office No. 4, First Floor,
CSC pocket E Market, Mayur Vihar Phase II, New Delhi-110091, India is the Publisher of Journals. Statements and
opinions expressed in the Journal reflect the views of the Author(s) and are not the opinion of JournalsPub unless so stated.
Subscription Information and Order
Cost of Journal
National Subscription
Rs. 3000/- per Journal (includes 2 print issues), Single Issue copy purchase Rs.1800/copy
International Subscription
Online Only- $99, Print Only-$149 (includes 2 print issues)
Online + Print-$199 (includes 2 print issues + online access of published back volumes )
To purchase print compilation of back issues please send your query at [email protected]
Subscription must be prepaid. Rates outside the India include speed delivery charges. Prices subject to change without
notice.
Mode of Payment: At par cheque, Demand draft, and RTGS (payment to be made in favor of Dhruv Infosystems Pvt. ltd.,
payable at Delhi/New Delhi.
Online Access Policy
A). For Authors:
In order to provide maximum citation and wide publicity to the authors work, JournalsPub also have Open Access Policy;
Authors who would like to get their work open access can opt for Optional Open Access publication at nominal cost as
follows:
India, SARC and African Countries: INR 1500 including single hard copy of Author's Journal.
Other Countries: USD 200 including single hard copy of Author's Journal.
B.) For Subscribers:
Online access will be activated within 72 hours of receipt of the payment (working days), subject to receipt of correct
information on user details/Static IP address of the subscriber.
The access will be blocked:
If the user requests for the same and furnishes valid reasons for blocking due to technical issue. Misuse of the access rights
as per the access policy.
Advertising and Commercial Reprint Inquiries: JournalsPub with wide circulation and visibility offer an excellent media
for showcasing/promotion of your products/services and the events-namely, Conferences, Symposia/Seminars etc. These
journals have very high potential to deliver the message across the targeted audience regularly with each published issue.
The advertisements on bulk subscriptions, gift subscriptions or reprint purchases for distribution etc. are also very
welcome.
Lost Issue Claims: Please note the following when applying for lost or missing issues:
Claims for print copies lost will be honored only after 45 days of the dispatch date and before publication of the next issue
as per the frequency.
Tracking id for the speed post will be provided to all our subscribers and the claims for the missing Journals will be
entertained only with the proofs which will be verified at both the ends.
Claims filed due to insufficient (or no notice) of change of address will not be honored.
Change of Address of Dispatch should be intimated to JournalsPub at least 2 months prior to the dispatch schedule as per
the frequency by mentioning subscriber ID and the subscription ID.
Refund requests will not be entertained.
Legal Disputes
All the legal disputes are subjected to Delhi Jurisdiction only.
If you have any questions, please contact the Publication Management Team:
[email protected]; Tel: +91 0120-4347644.
International Journal of
Biochemistry and Biomolecules
International Journal of Biochemistry and Biomolecules the main aim of this journal is to create awareness
in the scientific community and to provide a platform for discussion in the field of biochemistry and
biomolecules. Precisely, journal deals with recent advancement in protein folding, purification, bio-
separation and other related fields of biochemistry.
Focus and Scope of the Journal Metabolome
Metabolomics
Molecular medicine
Plant biochemistry
Proteolysis
Biological macro and small molecule
Biochemical processes
Molecular-scale
Fermentation, biochemical and bioreactor engineering
Proteomics, functional genomics, metabolomics
Chiral compounds production
Bio separation, purification, protein refolding
International Journal of Biochemistry and Biomolecules is published twice a year (bi-annual) by
JournalsPub an imprint of Dhruv Infosystems Pvt. Ltd., India. The outlooks stated in the articles do not
essentially reflect of the publisher. The publisher does not endorse the quality or value of the
advertised/sponsored products described therein. Please consult full prescribing information before issuing
a prescription for any products mentioned in this publication.
No part of this publication may be reproduced, stored in retrieval or transmitted in any form without written
permission to the publisher.
To cite any of the material contained in this journal, in English or translation, please use the full English
reference at the beginning of each article. To reuse any of the material, please contact JournalsPub
PUBLICATION MANAGEMENT TEAM
INTERNAL MEMBERS
Associate Manager
ChairmanMr. Puneet Mehrotra
Managing Director,JournalsPub,
New Delhi
Hidam Renubala
Ankita Singh
Deepika Bhadauria
Rekha Rani
Commissioning Editors
Dr. Chhavi Goel
Manisha Dhoble
EDITORIAL BOARD MEMBERS
Dr.Ashok Kumar Kulkarni Department of Physiology, MediCiti Institute of Medical Sciences, Medchal. Secunderabad (A.
P), India
Dr. Promila SharmaDepartment of Biotechnology,
Graphic Era University, Uttarakhand, India
Dr. Brijesh PandeyAmity University,
Uttar Pradesh, Lucknow, India
Dr. P Mary Anupama Department of Biotechnology, ANITS,
Sangivalasa, Visakhapatnam (A.P.), India
Dr. S. Seethalaksmi Vivekanandha College of Arts & Sciences for women, Periyar University, Elayampalayam,
Tiruchengod
Dr. Biswajit Majumdar Calcutta University, Institute of Post Graduate Medical Education and Research [IPGMER]
/University College of Medicine [UCM]
Dr. Agnishwar Girigoswami Medical Bio-nanotechnology, Faculty of Allied
Health Sciences Chettinad Academy of Research & Education Kelambakkam, Chennai, India
Dr.Arun Kumar Department of Biochemistry,
Manipal College of Medical Sciences, Nepal
Dr. Durgadas Govind Naik, Management and Science University,
Malaysia
Ashish Runthala Department of Biological Sciences, Birla
Institute of Technology & Science Pilani, Pilani (Rajasthan), India
Dr. Indraneel Ghosh Manager Systems Biology Department Sun Pharmaceuticals Advanced Research Centre
Limited, Vadodara (Gujarat), India
Dr. Yousef RasmiClinical Biochemistry, Faculty of Medicine
Urmia University of Medical Sciences (UMSU) Urmia, Iran
Ajay KumarGalgotias University, Greater Noida (U.P.),
India
Dr. Arvind DiwanMahatma Gandhi Mission Institute of Health
Sciences, Maharashtra, India
Dr. Ir. Sreenivas Reddy Bathula Department of Biotechnology, Bapuji Institute of
Engineering & Technology, Karnataka, India
Dr. Dinesh KumarHorticulture (Post harvest Technology)
National Research Centre for Citrus, Nagpur (Maharahtra), India
Dr. Ir. Sreenivas Reddy Bathula Department of Biotechnology, Bapuji Institute of
Engineering & Technology, Karnataka, India
Dr. Lonchin SugunaDepartment of Biochemistry Central Leather
Research Institute Adyar, Chennai, India
Dr. S Chidananda Sharma Department of Microbiology and
Biotechnology, Bangalore University, Karnataka, India
Prof. Dheera Sanadhya Jaipur National University,
Rajasthan, India
EDITORIAL BOARD MEMBERS
Dr. Rajat BanerjeeDepartment of Biotechnology, University of
Calcutta, India
Dr. B. C. Guha Centre for Genetic Engineering and
Biotechnology, University of Calcutta, India
Jay Prakash Sah Pokhara University, Nepal
Dr. K.S. KarthikeyanEndocrinology and Metabolism Division,
National Institute of Nutrition, Indian Council of Medical Research, Hyderabad, India
Dr. Saher Mahmood AljamaliBiology Department, Kufa University, Iraq
Dr. M. Anusuyadevi JayachandranMolecular Gerontology Laboratory,
Department of Biochemistry, Bharathidasan University, Tamil Nadu, India
Dr. Devarakonda Srinivasa Rao Department of Biotechnology Acharya
Nagarjuna University, Guntur (DT), India
Dr. Shashi Bhushan Food and Nutraceutical Lab, Division of
Biotechnology, CSIR-Institute of Himalayan Bioresource Technology, India
Dr. Shikha Suman Department of Botany, Banaras Hindu University, Varanasi (Uttar Pradesh),
India
Dr. Vishwanath B Chachadi Deptartment of Biochemsitry,
Karnatak University, Dharwad, India
Dr. Tashfeen Ashraf Assistant Professor, Gautam Buddha University,
UP, India
Dr. Vishwas TripathyAssistant Professor, Gautam Buddha
University, UP, India
From the Editor's Desk
Dear Readers,
We would like to present, with great pleasure, the inaugural volume of a new scholarly
journal, International Journal of Biochemistry and Biomolecules. This journal is part of
the Applied Sciences, and is devoted to the scope of present Biochemistry and
Biomolecules issues, from theoretical aspects to application-dependent studies and the validation of
emerging technologies.
This new journal was planned and established to represent the growing needs of Biochemistry and
Biomolecules as an emerging and increasingly vital field, now widely recognized as an integral part of
scientific and technical investigations. Its mission is to become a voice of the Biochemistry and
Biomolecules, addressing researchers and practitioners in this area.
The core vision of International Journal of Biochemistry and Biomolecules in JournalsPub is to propagate
novel awareness and know-how for the profit of mankind ranging from the academic and professional
research societies to industry practitioners in a range of topics in Biochemistry and Biomolecules in
general. JournalsPub acts as a pathfinder for the scientific community to published their papers at
excellently, well-time & successfully. International Journals of Biochemistry and Biomolecules focuses on
original high-quality research in the realm of Metabolome, Metabolomics, Molecular medicine, Plant
biochemistry, Proteolysis, Biological macro and small molecule, Biochemical processes etc.
The Journal is intended as a forum for practitioners and researchers to share the techniques of Biochemistry
and Biomolecules and solutions in the area. Many scientists and researchers have contributed to the
creation and the success of the Biochemistry and Biomolecules. We are very thankful to everybody within
that community who supported the idea of creating an innovative platform. We are certain that this issue will
be followed by many others, reporting new developments in the field of Biochemistry and Biomolecules.
This issue would not have been possible without the great support of the Editorial Board members, and we
would like to express our sincere thanks to all of them. We would also like to express our gratitude to the
editorial staff of JournalsPub, who supported us at every stage of the project.
It is our hope that this fine collection of articles will be a valuable resource for Biochemistry and
Biomolecules readers and will stimulate further research into the vibrant area of Biochemistry and
Biomolecules.
Puneet Mehrotra
Managing Director
1. Antimicrobial and Antioxidants Screening Through Phytochemical Evaluation and Nutrient Analysis of Different Medicinal Trees Swati Bhardwaj 1
2. Investigation of Systemic Acquired Resistance Establishment in Tomato Plants by Application of Marigold Extract Kumari Anukrati 14
3. A Report: New COMPASS Platform Points Directly to Protein's Likely StructureSurjit Sharma 25
4. Understanding Structure of HIV-1 Protease Vital to Development of Next-Generation HIV DrugsAnuradha Chaudhary 27
5. Phytochemical Analysis and Antibacterial Activity of Different Leaf Extracts of Murraya koenigiiRashmi, Jyoti Bisht, Naveen G 29
Contents
IJBB (2016) 1-13 © JournalsPub 2016. All Rights Reserved Page 1
International Journal of Biochemistry and Biomolecules Vol. 2: Issue 2
www.journalspub.com
Antimicrobial and Antioxidants Screening Through
Phytochemical Evaluation and Nutrient Analysis of Different
Medicinal Trees
Swati Bhardwaj* Codon Biotech Private Limited, Noida, U.P., India
ABSTRACT
The aim of present study is to detailed comparison of various extracts of aerial parts of Neem, Jamun and Mast Tree as potent anti-oxidative and antimicrobial agent and their protein sequences in an attempt to provide a direction for further research. The purpose of extraction was to check the antioxidant activities of leaves and stem barks of testing plant by using different in vitro antioxidant assays. Well diffusion method is used for antibacterial activity determination against 4 different strains of bacteria. Protein profiling in the high- throughput mode is a most helpful procedure that permits development of reference databases for cells and tissues and execution of relative proteomics. In this paper we report the consequences of such studies keeping in mind the end goal to arrange future examinations towards the finding of new, strong and safe cancer prevention agent and antimicrobial mixes and framing the reason for cutting edge proteomic investigations.
Keywords: antioxidant, antibacterial, proteomics
INTRODUCTION
Various researches have been conducted in the field of aromatic and medicinal plants. It is concluded that these plants are the sources of different nutrient and non-nutrient chemicals, many of which shows antioxidant and antimicrobial quality. These properties can protect the human body against both cellular oxidation reactions and pathogens. Therefore, it is important to distinguish different types of medicinal plants for their antioxidant and antimicrobial prospective.[1–3] Plant medicines are the oldest medication known to people. In the present scenario, the requirements for plant products are growing expending all over the world. There are various publications in many
journals, national and international; we find an increasing number of research publications based on herbal drugs.[4] For thousands of years the useful qualities of plants have been identified in the Indian tradition. Every part of these trees has some medicinal property. They have been broadly used in ayurveda, unani and homoeopathic medicine. MATERIALS AND METHODS
Collection of Plant Materials Aerial parts viz. leaves and bark of Azadirachta indica, Polyalthia longifolia, Syzygium cumini Linn were collected locally; air dried separately in shade and then was coarsely powdered by using grinder (Table 1).
IJBB (2016) 14–24 © JournalsPub 2016. All Rights Reserved Page 14
International Journal of Biochemistry and Biomolecules Vol. 2: Issue 2
www.journalspub.com
Investigation of Systemic Acquired Resistance Establishment in
Tomato Plants by Application of Marigold Extract
Kumari Anukrati* Department of Biotechnology, Amity University, Noida, India
ABSTRACT
In this study an effort was made to understand the impact of marigold leaf extract on the expression and activity of defense enzymes; Peroxidase (POX) and Catalase and their ability to induce defense response in tomato plants. Effect of aqueous leaf extract of T. erecta was observed on activity of PR proteins POX and Catalase on seven week old tomato plants. Aqueous leaf extract of T. erecta was sprayed on the third nodal leaves from the base of each plant 7 week old tomato plants and activity of PR proteins POX and Catalase was studied. The extract was sprayed to 3rd nodal leaves of the host plants and the enzyme activities of the above stated proteins were assayed in the untreated leaves of the same plants. The results gave an outlook of induced changes in host plant due to introduction of a foreign component to the plant. The host plant tends to reduce its PR protein activity initially, but gradually it attains its normal expression, thereby, proving that marigold leaf extract do not impart any deleterious effect on the host plant. Keywords: catalase, enzyme, peroxidase
INTRODUCTION
Tomato (Lycopersiconesculentum) is the world’s largest vegetable crop. Tomato is a herb, usually a sprawling plant belonging to the Solanaceae family, widely cultivated for its edible fruit. The fruit is considered a vegetable and has a distinctive red color when ripe. It is a native of South America with a center of diversity in Peru. Thousands of cultivars have been selected and bred which vary in shape, size, and color. Why tomato was chosen as a host: Tomato was decided for the work in light of its financial significance for all tropical and sub-tropical locales of the world. It is agreeable to creating pharmaceuticals, especially for oral conveyance; for a considerable lot of similar reasons, it is a
famous vegetable. Its natural product does not contain poisonous substances and is tasteful uncooked. High temperature stress is known to lessen natural product set in tomato. Systemic acquired resistance (SAR) is a mechanism of induced defense that provides long-lasting protection to plants against pathogen. The systemic acquired resistance follows a prior localized exposure to a pathogen or a biotic elicitor. SAR is similar to the innate immune system that is found in animals, and thus conferring immunization to plants. In order to respond to pathogen, plants use pattern-recognition receptors to identify the microorganism, this recognition thus triggers an immune response. The first plant receptors of conserved microbial signatures were identified in
IJBB (2016) 25-26 © JournalsPub 2016. All Rights Reserved Page 25
International Journal of Biochemistry and Biomolecules Vol. 2: Issue 2
www.journalspub.com
A Report: New COMPASS Platform Points Directly to Protein's
Likely Structure
Surjit Sharma Department of Biotechnology, Dr. B. Lal Institute of Biotechnology, Jaipur, India
Searching for the precise, complexly folded three-dimensional structure of a protein can resemble hacking through a wilderness without a guide: a long, intensive process with uncertain direction. University of Illinois scientists developed another approach, named COMPASS that focuses specifically to a protein's likely structure utilizing a combination of advanced molecular spectroscopy techniques, prescient protein- folding algorithms and image recognition software. Chad Rienstra, a Chemistry Professor and their team showed this process. They have taken a process that would take months and brought it down to hours, said Joseph Courtney, an Illinois graduate student. They expect this to not only accelerate the rate at which they can study proteins, but also increase its repeatability and the reliability. Proteins carry out functions inside the cell, and those functions are determined by the proteins' exact structures - the way they overlap and turn into a many-sided three-dimensional shape. Many diseases are caused about by a protein that is not acting effectively, or there is a lot of it. On the off chance that you can comprehend what the proteins appear as though, you can examine how they work, and you can configuration medications and medicines for those infections," Courtney said. "A noteworthy advantage is that on the off chance that you can design a drug to perfectly fit a
single protein that eliminates reactions, because it won't interact with other molecules." One key strategy for deciding a protein's share is a technique called X-ray crystallography. In any case, many medically interesting proteins - for instance, the fibrils that describe Parkinson's disease - do not form crystals, so researchers have swung to more progressed spectroscopic systems. Those systems oblige months to years of intensive data collection and analysis, taking various readings and measurements of the protein's spectrum. The Illinois group saw a chance to take advantage in structure prediction algorithms,, computational models that generate various conceivable ways a protein could fold base on its sequence. "The real deficiency of those displaying methodologies is that they never know whether they're correct," Rienstra said. "It's awesome to have models, yet despite everything it leaves a great many potential outcomes. We require some sort of test information to figure out which is the correct one." For COMPASS, the researchers depend upon a single spectrum measurement utilizing a technique called nuclear magnetic resonance, which gives a molecular “fingerprint” no two protein structures have a same spectrum [1]. The COMPASS platform takes a gander at the conceivable structures produced by the
IJBB (2016) 27-28 © JournalsPub 2016. All Rights Reserved Page 27
International Journal of Biochemistry and Biomolecules Vol. 2: Issue 2
www.journalspub.com
Understanding Structure of HIV-1 Protease Vital to Development
of Next-Generation HIV Drugs
Anuradha Chaudhary Department of Biotechnology, Lovely Professional University, Punjab, India
HIV, the virus that causes AIDS, has turned out to be one of the world's most serious health and advancement challenges. At present, there are roughly 36.9 million individuals living with HIV and a huge number of individuals have died of AIDS-related causes since the beginning of the epidemic in 1981. HIV not affects the health of individuals, it impacts households, and the communities and development and economic growth of nations there is still no cure (https://www.ornl.gov/). HIV treatment incorporates pharmaceuticals to prevent and treat the numerous opportunistic infections that can happen when the immune system is
compromised by HIV, and in addition the utilization of antiretroviral treatment (ART) to attack the virus itself, with the halting the development of AIDS. ART, initially presented in 1996, has prompted to dramatic reductions in morbidity and mortality; all around, 40% of individuals living with HIV are accepting treatment. HIV-1 protease is an enzyme in charge of development of virus particles into infectious HIV virions, which eventually prompts to the development of AIDS. Without effective HIV-1 protease activity, HIV virions remain non-infectious with this essential part in HIV replication, the disruption of HIV-1 protease action is along these lines a key focus for effective ART drugs (https://www.ornl.gov/).
IJBB (2016) 29-33 © JournalsPub 2016. All Rights Reserved Page 29
International Journal of Biochemistry and Biomolecules Vol. 2: Issue 2
www.journalspub.com
Phytochemical Analysis and Antibacterial Activity of Different
Leaf Extracts of Murraya koenigii
Rashmi, Jyoti Bisht*, Naveen G Department of Biotechnology, Sri Guru Ram Rai Post Graduate College, Dehradun, Uttarakhand, India
ABSTRACT
Murraya koenigii also known as a curry-leaf tree is use as a medicinal plant in India. In the present study, different phytochemicals were extracted and tested against Bacillus cereus, Pseudomonas aeuriginosa and Staphylococcus aureus by agar well diffusion method. Alkaloid, carbohydrate, tannins, terepnoids were present in all extracted samples, however cardiac glycosides and phylobatannins were extracted only in methanolic and ethanolic extracts of plant leaves sample. In all solvent extract from leaves of M. koenigii and minimum activity was recorded at 25 ppm of plant extract concentration. Maximum antibiotic activity was recorded with aqueous extract of leaves against S. aureus. In case of P. aeruginosa, all extracts were failed to show antibacterial activity. Keywords: antibacterial leaves extract, M. koenigii, phytochemicals
INTRODUCTION
Various medicinal systems like Ayurveda, Amchi, etc. and local health traditions are practiced in India, which utilize a large number of plants for treatment of various human and animal diseases. Those plants used for medicinal purpose are known as medicinal plants. The medicinal value of plant depends on numerous active compounds such as carbohydrates, proteins, enzymes, oils, terpenoids, phenolic compounds etc., which are helpful in improving the life and treatment of disease. Many plants have antimicrobial principles such as tannins, essential oils and other aromatic compounds. These compounds protect the plant from microbial infection and Deterioration [1]. The presence of important phytochemicals makes the plant useful against different diseases and has a strong of providing useful drugs of human use. Phytochemicals are regarded as secondary metabolites produced at very little amount
as the plant have little need for them. They are produced naturally in whole parts of the plant body; like bark, leaves, stem, root, flower, etc. [2]. The quantity and quality of phytochemicals present in plant parts may differ from one part to another [3]. One of the medicinally important herbs is M. Koenigii, has a placed in a family Rutaceae and normally known as curry-leaf tree. The plant is a local of India, Sri Lanka and other south Asian nations. It is discovered wherever in the Indian subcontinent [4]. The plant is exceptionally esteemed for its leaves a vital fixing in an Indian cooking to advance edacity and processing. The leaves, root and bark are tonic, for stomach pain. Leaves are utilized inside as a part of loose bowels, likewise checking regurgitating [5]. The leaves and roots are biting, harsh, cooling, hostile to
Biochemistry & Biomolecules
International Journal of
IJBBJul–Dec 2016
www.journalspub.com
Mechanical Engineering
Electronics and Telecommunication Chemical Engineering
Architecture
Office No-4, 1 Floor, CSC, Pocket-E,Mayur Vihar, Phase-2, New Delhi-110091, India
E-mail: [email protected]
¬ International Journal of Thermal Energy andApplications
¬ International Journal of Production Engineering¬ International Journal of Industrial Engineering
and Design¬ International Journal of Manufacturing and
Materials Processing¬ International Journal of Mechanical Handling and
Automation
« International Journal of Radio Frequency Design« International Journal of VLSI Design and Technology« International Journal of Embedded Systems and Emerging
Technologies« International Journal of Digital Electronics« International Journal of Digital Communication and Analog
Signals
« International Journal of Housing and Human SettlementPlanning
« International Journal of Architecture and InfrastructurePlanning
« International Journal of Rural and Regional PlanningDevelopment
« International Journal of Town Planning and Management
Applied Mechanics
5 more...
1 more...
2 more...2 more...
5 more...
Computer Science and Engineering « International Journal of Wireless Network Security« International Journal of Algorithms Design and Analysis« International Journal of Mobile Computing Devices« International Journal of Software Computing and Testing« International Journal of Data Structures and Algorithms
Nanotechnology« International Journal of Applied Nanotechnology« International Journal of Nanomaterials and Nanostructures« International Journals of Nanobiotechnology
« International Journal of Solid State Materials« International Journal of Optical Sciences
Physics
« International Journal of Renewable Energy and itsCommercialization
« International Journal of Environmental Chemistry« International Journal of Agrochemistry« International Journal of Prevention and Control of Industrial
Pollution
Civil Engineering« International Journal of Water Resources Engineering« International Journal of Concrete Technology« International Journal of Structural Engineering and Analysis« International Journal of Construction Engineering and
Planning
Electrical Engineering« International Journal of Analog Integrated Circuits« International Journal of Automatic Control System« International Journal of Electrical Machines & Drives« International Journal of Electrical Communication
Engineering« International Journal of Integrated Electronics Systems and
Circuits
Material Sciences and Engineering « International Journal of Energetic Materials« International Journal of Bionics and Bio-Materials« International Journal of Ceramics and Ceramic Technology« International Journal of Bio-Materials and Biomedical
Engineering
Chemistry « International Journal of Photochemistry« International Journal of Analytical and Applied Chemistry« International Journal of Green Chemistry« International Journal of Chemical and Molecular
Engineering
« International Journal of Electro Mechanics andMechanical Behaviour
« International Journal of Machine Design andManufacturing
« International Journal of Mechanical Dynamicsand Analysis
« International Journal of Fracture and damageMechanics
« International Journal of Structural Mechanicsand Finite Elements
5 more...4 more...
3 more...
Biotechnology « International Journal of Industrial Biotechnology and
Biomaterials« International Journal of Plant Biotechnology« International Journal of Molecular Biotechnology« International Journal of Biochemistry and Biomolecules« International Journal of Animal Biotechnology and
Applications3 more...
Nursing « International Journal of Immunological Nursing« International Journal of Cardiovascular Nursing« International Journal of Neurological Nursing« International Journal of Orthopedic Nursing« International Journal of Oncological Nursing
5 more... 4 more...
Subm
it
Your
Article 2
017
