SEMINAR PRESENTATIONTOPIC: INSULIN PUMPS

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Subject in charge:

Gowtham. MAsst. ProfessorRGIP

Presented by:Mariyam Sakeena T A1st MPharm

PharmaceuticsRGIP

INTRODUCTIONINTRODUCTION

People with diabetes cannot make their own insulin, a hormone that is normally secreted by the pancreas. Insulin is essential to metabolise sugar and hence generate energy.

Currently most diabetics inject insulin 2 or more times per day, with the dose injected based on readings of their blood sugar level.2

INSULIN PUMP

A personal insulin pump is an external device that mimics the function of the pancreas. It uses an embedded sensor to measure blood sugar level at periodic intervals and then injects insulin to maintain the blood sugar at a ‘normal’ level.Also known as Continuous Subcutaneous Infusion Therapy.

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The device configuration may vary depending on design.

The traditional pump includes: The pump (controls, processing modules

& batteries).A disposable reservoir for insulin (inside

the pump).A disposable infusion set, including a

canula for subcutaneous insertion (under the skin) & a tubing system to interface the insulin reservoir to the canula. 4

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EARLY INSULIN PUMPS (EARLY 1970S)

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Present Day Insulin PumpsPresent Day Insulin Pumps

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How to use an insulin pump•Filling reservoir with insulin.•Once reservoir is filled remove the plunger.•Attached to the infusion set.•Put the new infusion set into the pump.•Prime the pump by pushing a few command button on your pump.(priming means fill the cord with insulin. During priming insulin come out of the needle end of infusion set.)

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• Once it is primed ,set the needle end of the infusion set in to the Quick-serter.

• Sterilize the area planning to place the set.

• Quick-serter loads the set into the place with the push of a button.

• Remove the Quick-serter.

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INSULIN DELIVERY SYSTEM Data flow model of software-controlled insulin

pump:

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Insulinrequirementcomputation

Blood sugaranalysis

Blood sugarsensor

Insulindelivery

controller

Insulinpump

BloodBlood

parameters

Blood sugarlevel

InsulinPump control

commands Insulinrequirement

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1. Insulin pump2. Reservoir3. Infusion set4. Infusion set Insertion device Insulin pump: A small durable medical device that

has,◘ Buttons to program your insulin.◘ LCD screen to show what you are

programming.

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◘ Battery compartment to hold 1 AAA alkaline battery.

◘ Reservoir compartment that holds insulin.

• Reservoir: A plastic cartridge that holds the

insulin that is locked in to the insulin pump.

It comes with a transfer guard that assist with pulling the insulin from vial in to the reservoir.

A reservoir can hold up to 300 units of insulin & is charged every 2-3 days.

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• Infusion set: An infusion set includes a thin tube

that goes from the reservoir to the infusion site on your body.

The canula is inserted with a small needle that is removed after it is in place.

It goes in to the sites on your body similar to where you give your insulin injection.

The infusion set is changed every 2-3 days.

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• Infusion set insertion device: An infusion set is placed in to the

insertion device & with a push of a button , the infusion set is inserted quickly & easily.

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Dosing of insulin:•The insulin pump delivers a single type of rapid acting insulin in 2 ways.a.A bolus dose: That is pumped to cover food eaten or to correct a high blood glucose level.b.A basal dose: That is pumped continuously at adjustable basal rate to deliver insulin needed between meals & at night.

CHARACTERISTICS OF AN IDEAL INSULIN PUMPDeliver drug with in prescribed rates

for extended periods (2-5 yrs).Accuracy & precision.Reliable.Chemically, physically & biologically

stable.Compatible with drugs.Non-antigenic & non-carcinogenic.Must have over dose protection.Convenient to use. 19

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• Implantable by local anesthesia.• Able to monitor the performance of

the pump.• Must be sterilizable.• Have wide delivery rate for basal &

bolus deliveries to meet patient variability.

• Long reservoir & battery life & easy programmability.

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Insulin pump today•ACCU-CHEK SPIRIT-ROCHE.•AMIGO-NIPRO CORPORATION.•DANA DIABECARE IIS-SOAIL DEVELOPMENT.•MINIMED PARADIGM REVEL-MEDTRONIC.•OMNIPOD-INSULET CORPORATION.•ONE TOUCH PING – ANIMAS CORPORATION.

EG: ♠ MINIMED 630G INSULIN PUMP• Waterproof protection.• Color screen with auto-brightness.• Easy-to-use menu and buttons.• Polished black exterior finish;

easily customizable with a wide variety of personalized skins.

• Highly accurate wireless CONTOUR®NEXT LINK 2.4 meter (a MiniMed system exclusive).

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• Quick, easy delivery of a bolus.• Small device worn on your body that

continuously delivers insulin.• Tubing changes needed only every

two or three days.• Multiple insulin delivery settings.• Flexible design that moves with your

body.• Glucose readings in every five

minutes, right on your pump.

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• Tracks your levels throughout the day, showing the effects of food, exercise and other activities.

• Up-to-date information that makes it easier to spot trends and make adjustments.

[Exclusive Contour® next Link 2.4 Meter :Its wireless transmission of results helps to ensure accurate CGM calibration, insulin dosing, and remote bolusing in an easy-to-use sleek design.]

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♠ ACCU- CHECK INSULIN PUMP SYSTEM:

The Accu-Chek Insight insulin pump system offers blood glucose monitoring, bolus advice, insulin delivery and data management in one system.

FEATURES• Easy and intuitive for improved

handling.• Full colour display with resistive

touchscreen for a modern feel. 27

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• Simple on screen instructions for easy navigation.

• Proven bolus advisor  to help improve your glycaemic control.  

• Multiple reminders and warnings to give you peace of mind.  

• Full remote control of the pump via the handset - no need to get the pump out.

• Personalised bolus advice adapted to your needs. 

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• Electronic diary with full colour reports and graphs for data management on the go.  • Pre-filled cartridges of insulin - no

need to fill cartridges by hand.• Zoom function and coloured display

 • Simple on screen instructions for

priming infusion sets.

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ACCU CHECK INSULIN PUMP SYSTEM

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Advantages of insulin pump :•Increased flexibility in lifestyle.•Predictable insulin delivery.•Precise insulin delivery.•Reducing episodes of severe hypoglycemia.•Reducing wide fluctuation in blood glucose.Disadvantages of insulin pump:•Risk of skin infection at the catheter site.•Risk of diabetic ketoacidosis from pump malfunction or absorption problems.

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• Cost of pumps are expensive.• Letting others know that you have

diabetics.

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