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Cell & Molecular Biology

Intro to cells

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Slides for the discussion of Essential Cell Biology chapter 1 and The Machinery of Life chapters 1 and 5.

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Page 1: Intro to cells

Cell & Molecular

Biology

Page 2: Intro to cells

Cells

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“fundamentalunits of life...”

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Figure 1-1a Essential Cell Biology (© Garland Science 2010)

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Figure 1-1b Essential Cell Biology (© Garland Science 2010)

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Figure 1-1c Essential Cell Biology (© Garland Science 2010)

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Figure 1-1d Essential Cell Biology (© Garland Science 2010)

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Figure 1-1e Essential Cell Biology (© Garland Science 2010)

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Microscopes

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Bright field, 400xHematoxylin stained

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Bright field, 1000xHematoxylin stained

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Fluorescence, 1000xActin-labeled

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Fluorescence, 400xActin-labeled + Nucleus-labeled

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Fluorescence, 1000xActin-labeled + Nucleus-labeled

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Scanning ElectronMicroscope

http://commons.wikimedia.org/wiki/File:Hela_Cells_Image_3709-PH.jpg

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The

CentralDogma

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TheFlow of Biological

Information

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Genome

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Prokaryotic Cells

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Figure 1-11 Essential Cell Biology (© Garland Science 2010)

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Bright field, 1000xCoomassie Blue stained

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Bright field, 1000xHematoxylin stained

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Eukaryotic Cells

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Giardia

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Organelles

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Figure 1-8a Essential Cell Biology (© Garland Science 2010)

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Assignment 2

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Find out and tell us aboutan organelle

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The Nucleus

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Figure 1-15 Essential Cell Biology (© Garland Science 2010)

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Figure 1-16 Essential Cell Biology (© Garland Science 2010)

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Mitochondria

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Figure 1-18 Essential Cell Biology (© Garland Science 2010)

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Figure 1-19 Essential Cell Biology (© Garland Science 2010)

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Chloroplasts

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Figure 1-20 Essential Cell Biology (© Garland Science 2010)

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Figure 1-21 Essential Cell Biology (© Garland Science 2010)

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TheEndoplasmicReticulum

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Figure 1-22 Essential Cell Biology (© Garland Science 2010)

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The Golgi Apparatus

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Figure 1-23 Essential Cell Biology (© Garland Science 2010)

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The Cytoskeleton

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Lysosomes

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Peroxisomes

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Putting it all together

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Figure 1-24 Essential Cell Biology (© Garland Science 2010)

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Model Organisms

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Easy to GrowEasy to ManipulateSimpleWell CharacterizedRepresentativeHomologous Genes

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Bright field, 1000xCoomassie Blue stained

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Figure 1-32 Essential Cell Biology (© Garland Science 2010)

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Figure 1-33 Essential Cell Biology (© Garland Science 2010)

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Figure 1-34 Essential Cell Biology (© Garland Science 2010)

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Figure 1-38 Essential Cell Biology (© Garland Science 2010)

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Figure 1-39 Essential Cell Biology (© Garland Science 2010)

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Figure 1-40 Essential Cell Biology (© Garland Science 2010)

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Putting it all together