EuroDISH in Igls as work in progress

www.eurodish.eu13/02/201

5p. 1

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EuroDISH project:

The need for a Food And

Health

Research InfrastructureFebruary 2015 Igls, Austria

Krijn J. Poppe


5p. 2

Need for food policy and research:healthy diet – healthy life / aging

Agrofood sector

Land use, fish & farm, food

industry, retail,..

Health sectorMedical care &

cure, treatment, farma, ...

Most policies, public and private

investments are in agriculture or health

Policy will not only pay attention to curative

illness but to preventive health, more food policy

Due to neuro-science and ICT we will learn more on individual behaviour in next

years

ConsumerD – I – S – H

(EuroDISH)

private

public

private

public

Grant no 311788-CSA-SA

Research on relation food and health needs strengthening


5p. 3

Intake of

food and

nutrients

Health and

disease risk

Status and

function of

the body

Foods,

frequency,

amounts.

Lifestyle, e.g.,

physical activity

smoking,

drinking,

sexual activity

Fitness, fatness,

blood pressure

vascular stiffness;

serum cholesterol,

carotid artery

thickness,

atherosclerosis,

cognitive function;

mutation &

methylation.

Infection;

myocardial

infarction;

cancer;

fractures;

dementia.

Healthy life

expectancy,

mortality.

Major building blocks

Determinants

of diet and

lifestyle

Availability,

price, taste,

cultural

values and

beliefs,

attitude, PH-

intervention

campaigns,

education,

SES, age,

sex,

life cycle, etcGrant no 311788-CSA-SA

Krijn Poppe, Pieter van ‘t Veer and Karin Zimmermann

Studying the need for food and health research infrastructures in Europe


5p. 4

Intake of

food and

nutrients

Health and

disease risk

Status and

function of

the body

Foods,

frequency,

amounts,

physical activity.

Lifestyle, e.g.,

smoking,

drinking,

sexual activity

Fitnes, fatness,

blood pressure

vascular stifness;

serum cholesterol,

carotid artery

thickness,

atherosclerosis,

cognitive function;

mutation &

methylation.

Malaria or GI-

infection.

Myocardial

infarction.

Cancer of

breast, colon,

prostate.

Hip/leg fractures,

dementia.

Healthy life

expectancy,

mortality.

Major Research Questions

Determinants

of diet and

lifestyle

Availability,

price, taste,

cultural

values and

beliefs,

attitude, PH-

intervention

campaigns,

education,

SES, age,

sex,

life cycle, etc

Diet

What are

we

eating?

Food

(pattern) &

Nutrient

(status)

Effect

How does

it matter to

health?

Mechanisms

and disease

outcomes

Behaviour

Why are

we eating

this?

Food choice

& change

Public Health

Interventions

Psycho-social &

environmental

research, GIS &

GPS

Monitoring &

Surveillance

Innovative

technologies & food

products

Biomedical Research

New products for

people at risk

Grant no 311788-CSA-SAKrijn Poppe, Pieter van ‘t Veer and Karin Zimmermann



5p. 5

Consumer Complexity



5p. 6

Food Policy Research needed

(c) Barilla Food Centre, 2009


5p. 7

Research Infrastructures supports first class research and innovation

Help to shape scientific

communities:

Attract young people to

science & attract the

best researchers from

around the world,

Build bridges between

national research

communities and

scientific disciplines via

users from different

countries

Research Innovation

Unique research services,

facilities, resources

and related services

‘single-sited’, ‘distributed’, ‘virtual’

scientific discoveries

& technological development

Education


ESFRI – Strategic Working

Group Health and Food


5p. 8

Definition Research Infrastructure

Facilities, resources or services of a unique nature identified

by research communities essential to conduct top-level

research activities. Include

• Hard Infrastructures such as major buildings, equipment

and instruments, knowledge-containing resources such as

e-platforms and data banks.

• Soft Infrastructures such as unique data management,

interpretation and handling capacities, harmonisation of

data, training staff, professional networks and knowledge

transfer.

• May be “single-sited”, “distributed”, or “virtual”.

8

Research questions e.g.,

Why?What?How?

Social science

data archive

e.g., CESSDA

Food access

& availability

instruments

Sensory, label,

sustainability

data to link with

food

composition

Determinants

data to link with

genetic bio-

banks (twin

registries)

Socio-cultural

environment

data

Health-related

behaviour data

(adolescent,

obese)

D

Decision-

making (eye-

tracking)

instruments

Neurological

(brain/ gastro)

facilities

Behavioural

intervention

Food

labelling/

product

tracking tools

Sensory

facilities

Dietary

behaviour

observatory

facilities

Policy

impact

assessment

Food

classification &

description

systems

Dietary

collection

tools e.g., e-

SMP

IARC/WHO

Personalised

nutrition

advice

Nutrient

calculation

tools

Biomarkers

for intake

DRV & FBDG

data

Composition

databases e.g.,

EuroFIR,

INFOODS

Food

consumption

databases

Food

processing, non-

nutrient content

Intake data to

link with dietetic

advice & health

outcome

Food

classification

/description

converters

Supporting (soft) RI: Standard operating procedures (study design, data collection/assay, analysis, interpretation or reporting to enable data harmonisation /sharing)

Relevant areas not mapped:

Toxicology, food safety and risk – benefit analysis research

Food environment & wider food chain research e.g., agri-food, climate, sustainability

Research & institutional governance e.g., ethics

Clinical

platforms &

investigation

centres e.g.,

ECRIN

Bio-statistics/

bio-

informatics

facilities

Clinical

contract

research

organisations

e.g., biofortis

Omic science

platforms for

nutrition

research

Biological clinical

& translational

data e.g., ELIXR

Mechanistic

approaches

for

translational

research

Genome &

data/bio-bank

Prog/diagnostic &

therapeutic bio-

marker bio-bank

e.g., BBMRI

Nutritional

phenotype

data/bio-bank

Nutrition status

of vulnerable/

seldom studied

populations

Status

biomarkersCancer registry,

cohorts,

databases/bio-

banks e.g., EPIC

CVD registry,

cohorts,

databases/ bio-

banks e.g., EPIC

Obesity

databases/bio-

banks

Reproduction/

birth cohort/ long-

term effect

linkage data

DM cohorts,

databases e.g.,

EPIC-Interact

Health &

transversal

issue bio-

bank network

Obesity

network/

centres

Pre-conception

cohorts for early

nutrition – health

impact

Couple-centred

cohort for diet –

fertility

Su

pp

ort

ing

RI:

Info

rmatio

n C

om

munic

atio

n T

echnolo

gy (

ICT

)

Proteomic

data

interpretation

tools/ centre

Non-invasive

CVD markers

Su

pp

ortin

g (s

oft) R

I:T

rain

ing

Based on a mapping of existing “research infrastructures”

I

SH

Cancer trial &

clinical study

network e.g.,

EORTC

Major

equipment/

instrument

RI

Knowledge

containing

resource RI

Potential

(past/ future)

RI

RI gap/

needMapped

existing RI

Supporting (soft) RI: Multi-disciplinary/national networks

KEY

Conceptual design: Food And Health Research Infrastructure (FAHRI)

Centre for Pan-EU food and nutrition surveillance

Reference centre for innovative assessment of diet and lifestyle

Knowledge centre for food practices

Centre for Pan/EU nutritional health

cohorts &interventions

Reference centre for innovative markers for

nutrition and health

Knowledge centre for molecular nutrition

and systems biology

StandardizedDISH-metric &

ICT-infrastructure

Governance & management

Deter-minants

Intake Health

Status

Entr

yp

oin

t

ELIXIR PRECIOUS BIOMEDBRIDGES

RICHFIELDS NUGO ECRIN QUALIFY 10


5p. 11

Smart Food and Health Services: new ways to capture data


5p. 12

Data complexity: behaviour and health



5p. 13

Pitch summarized

Krijn Poppe, Pieter van ‘t Veer and Karin Zimmermann



The European

Food and

Health domain

deserves up

to date

insights into the consumer,

to support his

active and

healthy life.


5p. 14

Thank you for your

attention.

www.eurodish.eu

[email protected]

wageningenUR.nl/lei