MULTIPLE ORGAN SUPPORT THERAPY FOR CRITICALLY ILL PATIENTS
MULTIPLE ORGAN SUPPORT THERAPY FOR CRITICALLY ILL PATIENTS
1Prof. Dr. RS Mehta, BPKIHS
Introduction The intensive care unit (ICU) is the hospital
facility within which the highest level of continuous patient care
and treatment care are provided.
ICU cases include a variety of severe cases due to major
surgical interventions, trauma, hemodynamic instability, sepsis and
so on.
All of these factors can easily lead to MODS (multiple organ
dysfunction syndromes). 2Prof. Dr. RS Mehta, BPKIHS
Introduction Multiple organ dysfunction syndromes are the
leading cause of mortality in critically ill patients and is
responsible for a large amount of healthcare expenditure.
Since the probability of death is directly correlated to the
number of failing organs beyond the kidney and the degree of
physiological derangement, a clinically sensible approach is to
broaden the spectrum of physiological endpoints targeted by
extracorporeal therapy. 3Prof. Dr. RS Mehta, BPKIHS
Introduction Blood is the vital element that regulates all body
systems from cellular to organ level.
A multiple organ support therapy is a logical and should be the
goal of extracorporeal blood purification in the intensive care
unit.
4Prof. Dr. RS Mehta, BPKIHS
Indication of ICU admissionPatients requiring, likely require,
advanced respiratory support alone.
The patient requiring support of two or more organ systems.
Patients with co-morbidity who require support for an acute
reversible failure of another organ system
5Prof. Dr. RS Mehta, BPKIHS
Assessment6Prof. Dr. RS Mehta, BPKIHS
Clinical feature of patient requiring organ system
supportConfusionDecrease GCSShortness of breathRapid or irregular
heart beatRapid, shallow breathing
7Prof. Dr. RS Mehta, BPKIHS
Clinical feature of patient requiring organ system support
Grunting soundsFlaring of the nostrilsDecrease urine
output=(
