DevelopingEndovascular Grafts in the

former USSR in 1980s

Professor Nikolay VOLODOS,

Kharkov, UKRAINE

RADIAL ZIG-ZAG SHAPED CYLINDRYCAL RADIAL ZIG-ZAG SHAPED CYLINDRYCAL

SPRING (STENT) CREATED IN SPRING (STENT) CREATED IN 19831983

Devices for studying radial forces of Devices for studying radial forces of stentsstents

OUR FIRST EXPERIMENTAL OUR FIRST EXPERIMENTAL STENT-GRAFTSTENT-GRAFT

Protected by

National

Patent

from 22 May 1984

THE SCHEME OF EXPERIMENT TO STUDY BEHAVIOR OF THE SCHEME OF EXPERIMENT TO STUDY BEHAVIOR OF AN ENDOPROSTESIS IN A SEGMENT OF AORTA IN THE AN ENDOPROSTESIS IN A SEGMENT OF AORTA IN THE

CONDITIONS OF A PULSATING FLOWCONDITIONS OF A PULSATING FLOW

Transport part

Joining unit

Packing part

THE PRINCIPAL SCHEME THE PRINCIPAL SCHEME OF OUR FIRST OF OUR FIRST

DELIVERY SYSTEM:DELIVERY SYSTEM:

BALLOON CATHETER FOR CONTROLLED BALLOON CATHETER FOR CONTROLLED DILATATIONDILATATION OF OUR OWN ORIGINAL OF OUR OWN ORIGINAL

CONSTRUCTIONCONSTRUCTION

Outer latex layer

Fabric layer

Inner latex layer

Catheter

CATHETER WITH METALLIC CATHETER WITH METALLIC MARKERS OF OUR OWN MARKERS OF OUR OWN

ORIGINAL CONSTRUCTIONORIGINAL CONSTRUCTION

THE ANIMAL EXPERIMENTALTHE ANIMAL EXPERIMENTAL DELIVERY SYSTEM IN 1983 – 1984 DELIVERY SYSTEM IN 1983 – 1984

THE ANIMAL EXPERIMENTSTHE ANIMAL EXPERIMENTS

• A dog’s intra-operative A dog’s intra-operative angiogramangiogram

• 6 months after 6 months after procedureprocedure

THE DATE OF THE FIRST PROCEDURE

4 May 1985

THE FIRST PATIENT: THE FIRST PATIENT: STENOSIS OF THE ILIAC ARTERY: STENOSIS OF THE ILIAC ARTERY:

MAY, 1985MAY, 1985

TRAUMATIC ANEURYSM OF THORACIC TRAUMATIC ANEURYSM OF THORACIC AORTA: MARCH, 1987AORTA: MARCH, 1987

ABDOMINAL AORTIC ANEURYSM: THE FIRST ABDOMINAL AORTIC ANEURYSM: THE FIRST ATTEMPT OF ENDOPROSTHETICS WITH THE USE ATTEMPT OF ENDOPROSTHETICS WITH THE USE OF BIFURCATED ENDOPROSTHESIS: DECEMBER, OF BIFURCATED ENDOPROSTHESIS: DECEMBER,

1989 1989

THE FIRST HYBRID PROCEDURE THE FIRST HYBRID PROCEDURE FOR AORTIC ARCH ANEURYSM: FOR AORTIC ARCH ANEURYSM:

JUNE, 1991JUNE, 1991

Volodos NVolodos N..LL., ., Karpovich IKarpovich I..PP., .,

Troian VTroian V..II., ., et alet al..

Clinical experience of the Clinical experience of the use of self-fixing synthetic use of self-fixing synthetic prostheses prostheses // // Angiologie. - Angiologie. - VASA. - 1991. Suppl.33. - VASA. - 1991. Suppl.33. - P.93-95.P.93-95.

AORTA-BRONCHIAL FISTULA: AORTA-BRONCHIAL FISTULA: ENDOPROSTHETICS OF THORACIC AORTA ENDOPROSTHETICS OF THORACIC AORTA

(VIA TWO ACCESSES): AUGUST, 1993(VIA TWO ACCESSES): AUGUST, 1993

Aorto-bronchialfistula

HYBRID PROCEDURES FOR ANEURYSMS, STENOSIS HYBRID PROCEDURES FOR ANEURYSMS, STENOSIS AND OCCLUSIONS OF ABDOMINAL AORTA VIA LEFT AND OCCLUSIONS OF ABDOMINAL AORTA VIA LEFT

COMMON ILIAC ARTERY FROM PARARECTAL COMMON ILIAC ARTERY FROM PARARECTAL APPROACH: 1APPROACH: 1999977

Academician Alexander ShalimovAcademician Alexander Shalimov

OUR FIRST VERSIONS OF SPRINGSOUR FIRST VERSIONS OF SPRINGS

Charles DotterCharles Dotter

We still managed to complete the whole cycle

• the idea of a self-fixing synthetic prosthesis with a stent inside as a fixing element) to making the stent itself and the endoprosthesis,

• - testing the material toxicity and performance capabilities of finished samples on models and animals to prove that they were safe to use,

• - designing and manufacturing systems to deliver and put stents and endoprostheses in the predetermined segment of the vessel bed,

• - the first procedure of a remote prosthetic repair, the first one in the world in clinic,

• - designing main types of endoprostheses and procedures including a combined (hybrid) prosthetic repair for various segments of the aorta and big vessels: aorta arch, descending aorta, abdominal aorta and iliac arteries.

I would like to say

• We are happy that our fate let us be among the first who were at the very beginning of the method that was totally revolutionary in treatment and changed the scheme of treatment of a lot of diseases and made it possible to save doomed patients.