Team E

Debbie Fernando

Alicia Shumpert

Candace Hume

Vashona Mack

HCS/551

February 24, 2014

Dr. Donna Fife

The Nervous System

Amyotrophic Lateral Sclerosis

Nervous System

Central

Peripheral

ALS (Lou Gehrig's Disease)

Motor neuron disease

Rapidly progressive

Attacks neurons - control voluntary muscle

Upper and lower motor neurons die

No communication between nerves and muscles

Diaphragm and chest wall muscles – no movement

Death

Familial tendency

5600 new cases annually

30,000 in US

60% Men

93% Caucasian

Men more commonly affected (changing)

Most develop between ages of 40 to 70

Most Common over 60

US and England have highest rates (Italy & Poland the

lowest)

International numbers may be affected

No racial or ethnic traits

Occurs as much as MS

No cure

Physical disability involving all limbs (Phelps, 2006)

Increased muscle weakness

Ineffective speech(Phelps, 2006)

Voice changes

Slurred speech

Difficulty swallowing (Phelps, 2006)

Difficulty breathing (Phelps, 2006)

No Cure

Hospice Care/Home Health Care

Pharmacotherapy

Riluzole

Lose muscle strength entire body(Young and

McNicoll, 1998)

Unable to communicate. (Young and McNicoll, 1998)

Inability to swallow. (Young and McNicoll, 1998)

Unable to breath

Survival rate 3-5 years

Age at diagnosis

Gender

Quick diagnosis from onset

Extremities vs. face

Death

Cannot swallow

Drooling

Choking

Cannot communicate with speech

Difficulty in rising from seat to stand

Difficulty in walking

Regular Exercise

Diet

Increase social activities

Weight maintenance

Usually maintain mentalities throughout

Speech Therapists

Adaptive Therapies

Mental Evaluations

Assistive Devices

Counseling or Therapy

Packard Center

The ALS Association

Muscular Dystrophy Association

International Alliance of ALS/MND Association

ALS Therapy Development Institute

Mayo Clinic

Clinical Trials

Fundraisers

Social Media

Support groups

Financial assistance

Hospice

Preparation for end of life

ALS-motor neuron disease

Rapid progression

No cure

Statistical data

Symptoms

Prognosis

Questions ???

ALS Association. (2014). Who Gets ALS? Retrieved from http://www.alsa.org/about-als/who-gets-als.html

ALS Therapy Development Institute. (2014). The ALS Community. Retrieved from http://www.als.net/ALS-Community/

Amyotrophic Lateral Sclerosis Fact Sheet. (2014). Retrieved from http://www.ninds.nih.gov/disorders/amyotrophiclateralsclerosis/detail_ALS.htm

Dalsgaard, M. K. (2006). Fuelling cerebral activity in exercising man. Journal of Cerebral Blood Flow and Metabolism, 26(6), 731-50. doi:http://dx.doi.org/10.1038/sj.jcbfm.9600256

Fabrega Jr., H. (1977). CULTURE, BEHAVIOR, AND THE NERVOUS SYSTEM. Annual Review Of Anthropology, 6419-455.

International Alliance of ALS/MND Associations. (2014). Background. Retrieved from http://www.alsmndalliance.org/about-us/

Lifetips. (2014). The Epidemiology of ALS. Retrieved from ALS Tips: http://als.lifetips.com/faq/113659/0/what-are-the-incidence-and-prevalence-rates-of-als/index.html

Mayer, J. D. (1981). GEOGRAPHICAL CLUES ABOUT MULTIPLE SCLEROSIS. Annals Of The Association Of American Geographers, 71(1), 28-31

Mayo Clinic. (2014). Amyotrophic lateral sclerosis. Retrieved from http://www.mayoclinic.org/diseases-conditions/amyotrophic-lateral-sclerosis/care-at-mayo-clinic/why-choose-mayo-clinic/CON-20024397

MDA/ALS Magazine. (2014). Factors in Survival. Retrieved from http://alsn.mda.org/article/factors-survival

MDA: Fighting Muscle DIsease. (2014). Speech and Communication. Retrieved from http://mda.org/publications/everyday-life-als/chapter-6

Meisler, J. (2001). Toward Optimal Health: The Experts Discuss Epilepsy. Journal Of Women's Health & Gender-Based Medicine, 10(7), 621-625. doi:10.1089/15246090152563498

Packard Center . (2014). ALS Facts and Statistics. Retrieved from Living with ALS: http://www.alscenter.org/living_with_als/facts_statistics.html

Phelps, J. (2006). Inflammatory enzyme modulates motor neuron damage in Amyotrophic Lateral Sclerosis. Environmental Health Perspectives, 114(12), 697

Pratt, A. J., Getzoff, E. D., and Perry, J. J. P. (2012). Amyotrophic lateral sclerosis: Update and new development. Degenerative Neuromuscular Disease, 2, 1-1

Rowland, L. P. (2001). Medical Progress - ALS. Retrieved from http://isites.harvard.edu/fu/docs/icb.topic1303034.files/case%203%20-%20suppplemental%20Readings

Young, J. M., and McNicoll, P. (1998). Against all odds: Positive life experiences of people with advanced Amyotrophic Lateral Sclerosis. Health and Social Work, 23(1), 35-43.