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Pistoia Alliance European Conference 2016

Kings College London

18 April, 2016

Free wifi via The CloudPlease connect to _The CloudFurther instructions available via Yapp or the conference webpage:

my.yapp.us/PISTOIAEUR16

www.pistoiaalliance.org/PISTOIAEUR16

AgendaPistoia Alliance European Conference 2016318 April, 20168.00am Registration8.30am Welcome and introduction9.00am Panel: Mobile and Wearables10.35am Coffee11.00am Panel: Robotics12.35pm Lunch1.30pm Panel: Big Data3.05pm Coffee3.30pm Startup Challenges4.45pm Closing notes5.00pm Reception (until 8pm)

Pistoia Alliance

A photographer is present!

Welcome and introduction

Steve Arlington, President, Pistoia Alliance

WelcomePistoia Alliance European Conference 2016618 April, 2016What do we want to achieve today?

Pistoia Alliance3 minutes on this slide - give brief answers to each of these four questions along the lines of encouraging collaboration, seeking support, encouraging engagement, etc. Highlight the fact that the panels are on topics of immediate relevance to the industry and open discussion is key to understanding where we can fit inRecognise the contribution of small businesses and reference the presentation of the Presidents Startup Challenge winners, and Mini Startup Challenge judging laterReiterate the importance of networking today, especially at the evening reception where all are welcome

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Six months is a long timePistoia Alliance European Conference 2016718 April, 2016Whats happened in the last six months?What changes have been made?What have been our major achievements?

Pistoia Alliance3 minutes fairly obvious how to ad-lib to this one I think but leave any project-specific achievements to the next slide, including the startup challenges

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Project successesPistoia Alliance European Conference 2016818 April, 2016

Pistoia Alliance3 minutes - Refer audience to our website for full details on all projects, PARTICULARLY CASE STUDIES ON FRONT PAGE from Roche, Pfizer, Novartis, etc. - but pick out in your talk here: HELM (see Claire Bellamy) HELM notaiton standard has been adopted by the FDA for submissions, and version 2.0 of the toolkit was released earlier this month (Apr 4th) CSCS (see Claire Bellamy also) - expert community funded for another year, updated country test datasets being developed Presidents Startup Challenge and Mini Challenge (see Richard Holland) popular, and high quality finalists and winners more on that this afternoon Two new projects now well underway Ontologies Mapping (see Ian Harrow) has delivered recommendations for best practices in ontology management and has started looking into the production of suitable tools, and Chemical Safety Library (see Gabrielle Whittick) has defined data standards for gathering information on reactions and is now working on defining a tool for reaction submission and searching Map of Alliances in a holding pattern waiting on third-party input from partners ELIXIR-BioSchemas and Daniels Business School at U.Denver, but it is informing our strategy work more on that in a minute

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Challenges facing the sectorPistoia Alliance European Conference 2016918 April, 2016The life sciences sector is undergoing significant change Underpinning many of these challenges are issues around R&DMany of the so-called easy targets have been identified and treatments developedThe industry now needs to focus on more complex and difficult targetsAssociated with this is an increased cost in R&D

Pistoia Alliance3 mins : Prepare the audience for where the future of collaboration is, what the immediate challenges are in the industry today TACTICAL is deliberately crossed out to emphasis that were trying to think bigger here. Link this in to the panel subjects today Mobile/Wearables, Robotics (incl. nanotech and 3d-printing), Big Data.

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Challenges facing the Pistoia AlliancePistoia Alliance European Conference 20161018 April, 2016The Pistoia Alliance has had an impact on life sciences R&D through pre-competitive collaborationIt has not been as significant or as wide ranging as hopedThere are some indications its impact may be diminishingTo ensure that the Pistoia Alliance is able to continue to contribute and to influence global R&D strategy at the highest levels, a new strategy is required

Pistoia Alliance3 mins : prepare the audience for why change is needed in terms of the future of the Alliance itself

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Strategy focus areasPistoia Alliance European Conference 20161118 April, 2016Build membership and alter structureGrow our membership depth and breadthEnsure we build on the excitement of our annual Presidents Startup ChallengeSet up an advisory board comprising industry leadersEstablish a Portfolio Investment CommitteePartner with other groups & not-for-profit organizations where there are clear synergies that deliver value to members

Pistoia Alliance12 minutes on this slide introduce the strategy, explain how it aligns with the industry needs and Pistoia challenges you outlined on the previous two slides, and say what you can about each of these four areas, explain to the audience where they can help us in the immediate to short term e.g. support, sponsorship, funding, ideas, etc.

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Your role in making today a successPistoia Alliance European Conference 20161218 April, 2016Discussion during breaks and reception today will be vital to kick-start our new strategyGetting the word to your colleagues will also help us reach the right people with the right message let us know how we can help you spread the wordPanel discussions today are the starting point, exploring areas we think are of interest and relevant to future success, but we need you the industry to tell us where to go nextFill in the survey prize for introducing the most new members within three months

Pistoia Alliance3 minute wrap-up, reminder that networking and discussion is key today, and hand over to yourself to change into the role of chair for the first session Richard will come on stage briefly to prep things and re-introduce you

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Mobile and wearablesPanel discussion(Chair) Steve Arlington, President, Pistoia AllianceSarah Haywood, CEO, MedCityYury Rozenman, Director of Business Development, Qualcomm LifeGareth King, Catapult Ventures

CoffeeNext session starts at 11am

RoboticsPanel discussion(Chair) Ashley George, Treasurer, Pistoia AllianceAndrew Hessel, Distinguished Research Scientist, AutodeskTed Pawella, Sr. Director Portfolio & Product Management, BIOVIA, Dassault SystemesSteve Rees, Vice-President of Screening Sciences and Sample Management, AstraZeneca

Lunchtime BOF: User-centered Design of Scientific Software

Carmen Nitsche will be leading a meeting over lunch

LunchNext session starts at 1.30pm

Big dataPanel discussion(Chair) Fiona Neilsen, CEO, DNAdigestAdam Auton, Senior Statistical Geneticist, 23andMeMathew Woodwark, Director of Research Bioinformatics, MedImmuneEric Little, Vice President Data Science, OSTHUS

CoffeeNext session starts at 3.30pm

Startup challenges

Richard Holland, Executive Director Operations, Pistoia Alliance

Presidents Startup Challenge 2015The Winners

Presidents Startup Challenge 2015Pistoia Alliance European Conference 20162218 April, 2016Encourage startups to engage with usPre-competitive collaboration is for everyoneLearn more about the latest trends in life science innovation from those that live and breathe itExpose our membership to new ideasHelp startups validate their business modelsPromote entrepreneurial activity that will one day lead to innovative new products and services

Media partner: Start-Up (Informa)

Pistoia AlliancePresidents Startup Challenge 2015Pistoia Alliance European Conference 20162318 April, 2016Business plan contest, Jul 15 Feb 16For life science startups worldwideAny new product or service that lowers the barriers to innovation in life science R&D31 entries, five finalists, two winners, all judges and mentors from our membershipFinalists: $5k and mentorship to prepare for round 2Winners: $15k and six months mentorshipRound 2 video pitches can all be found on our blog

Repositive and Novaseek are here today to present their video pitches and collect their awards

Pistoia AllianceWinner: Novaseek ResearchPistoia Alliance European Conference 20162418 April, 2016

Pistoia AllianceWinner: RepositivePistoia Alliance European Conference 20162518 April, 2016

Pistoia Alliance

Pistoia Alliance European Conference 20162618 April, 2016

Pistoia AllianceMini Startup Challenge 2016The Finalists

Mini Startup Challenge 2016Pistoia Alliance European Conference 20162818 April, 2016Business plan contest, smaller scale version of the Presidents Startup Challenge, Jan-Mar 2016Focus on UK and EU SMEsAreas of interest:Mobile Health and DataWearables and Internet of ThingsEntries were encouraged that could:Assist or advance life science Research and Development processes and capabilitiesProvide solutions to enhance and improve clinical researchDeliver solutions to automate or augment laboratory research efforts and processesEnable scientific discovery

Solutions that target current global healthcare events and challenges were of particular interest.Any patient or clinical related focus should be able to validate their claims scientifically or show intention to do so.

Pistoia AllianceMini Startup Challenge 2016Pistoia Alliance European Conference 20162918 April, 2016Business plans were submitted in round 1Round 2 live judging of pitches here today!Prizes:Five finalists: 1,000 eachCategorised scores, online judging took place late March, top five highest total scores went throughJudges choice: 10,000 and 3 months mentorshipCategorised scores, winner will be the one with the highest total scoreAudience choice: 5,000By popular vote, winner will be the one with the most votes

Pistoia AllianceMini Startup Challenge 2016Pistoia Alliance European Conference 20163018 April, 2016The round 2 judges are:Gareth King, Investment Manager GM&C Life Sciences Fund, Catapult VenturesNick Wright, VP & Global Head R&D Information, AstraZenecaAnthony Rowe, Director Translational Informatics and External Innovation, Johnson & JohnsonSergio Rotstein, Director Research Business Technologies, PfizerFiona Neilsen, CEO, RepositiveBennett Malbon, VP Technology, Novaseek Research

Pistoia AllianceMini Startup Challenge 2016Pistoia Alliance European Conference 20163118 April, 2016Each of the five finalists will now present:3 minute pitch2 minute Q&A

Audience: choose your favourite:Agewell Biometrics: EquilibriumTMAIMESmartbellMedexprimxRapid Tuberculosis

Judges: please take notes! Here are the pitches

Pistoia AllianceMini Startup Challenge 2016Pistoia Alliance European Conference 20163218 April, 2016Audience: return your voting slips to David Proudlock or Richard Holland

Judges: pass your scorecards to David Proudlock or Richard Hollandbe prepared to give informal verbal feedback during the reception

Results will be announced during the reception, as soon as the votes have been counted

Agewell Biometrics: EquilibriumTMAIMESmartbellMedexprimxRapid Tuberculosis

Pistoia AllianceClosing notes

Steve Arlington, President, Pistoia Alliance

Pistoia AllianceMini Startup Challenge 2016Winners will be announced during the receptionwith an introduction from Gareth King, Catapult VenturesPlease move upstairs to Chapters, and return your surveys and votes!

Reception sponsor:

Pistoia AllianceSee you in San Antonio!

info@pistoiaalliance.org@pistoiaalliancewww.pistoiaalliance.org