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Simon Thornber, project lead for the Pistoia Alliance Sequence Services Project, provides details on the goals and deliverables for Phase 2 of the project. The presentation was delivered at the Pistoia Alliance Annual Conference in Boston, MA, in April 2012.
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Pistoia – Sequence Services 2
24th April 2012Simon Thornber (Workgroup Chair)
Setting the Scene• Phase 1 (a quick reminder).
•Phase 2 Overview.
• The Pistoia Approach.
Phase 1
World Class Bioinformatics Software
Add private data
Business level security / cloud hosted
Ethical Hack
The data deluge
Taken from the Elixir business case
Launch of the 454 LifeSciencesPyrosequencing machine
(Mb/$) in a corporation
Open‐Source
• Some of the best NGS software is open‐source.•EBI / Broad Institute. (funding models / philosophies) • Great software written by people who use it.
• Where do you turn to for support?•Industry cannot cross their fingers & hope for community support on a project wiki.
• The politics of Open Source projects.
Security
Open‐Source Software is not always written with security concerns as a priority.
• We saw this from Phase 1. – was written to help good people do great things.
• A major part of testing in Phase 2.
• Pistoia is not going to publish the findings.• Nothing was found that isn’t fixable.• Some have more work to do than others.
Global & Externalised Projects
Rise in the number of global projects often with 3rd parties contributing.
This makes cloud hosted platforms attractive, and can reduce the risk of allowing 3rd parties inside corporate firewalls.
The Pistoia Approach
• A common set of requirements from a number of Pharmaceutical Companies.
• Shared risk funding to help kick‐start commercial services in this space.
Speak with a single voice.And do more…
Phase 2 – System Use Cases
10
Phase 2
Data Loading
Data Management
Simple Analysis pipelines
11
Ethical hack
Ease of use Secure
3 Different approaches to this challenge.