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Webinar Opportunities for orphan drug development in Horizon 2020 © ttopstart BV www.ttopstart.com [email protected] How to write a successful ERC Proof of Concept (PoC) grant ttopstart academy Jasper Levink – partner @ ttopstart January 2016

ttopstart academy: how to write a successful ERC PoC proposal

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Page 1: ttopstart academy: how to write a successful ERC PoC proposal

• Webinar• Opportunities for orphan drug

development in Horizon 2020© ttopstart [email protected]

How to write a successful ERC Proof of Concept (PoC) grant

ttopstart academy

Jasper Levink – partner @ ttopstart

January 2016

Page 2: ttopstart academy: how to write a successful ERC PoC proposal

Do you have an ERC Grant?

Then the ERC PoC programme can help to make the very first steps towards commercialisation.

And have you discoveredsomething new and exciting?

Page 3: ttopstart academy: how to write a successful ERC PoC proposal

Empowering biomedical researchers andentrepreneurs to establish breakthroughs

Page 4: ttopstart academy: how to write a successful ERC PoC proposal

Our success: > 90% success rate in ERC PoC applications

> 6 startups from ERC PoC projects

> 50% overall success rate in Horizon 2020

This presentation covers some key best practicesacquired over the years.

Presented following our FFWD methodology

ERC Proof of Concept

ERC PoC

Page 5: ttopstart academy: how to write a successful ERC PoC proposal

The European Research Council (ERC) supports the highest quality research in Europe through competitive funding. The ERC PoCprogramme aims to bridge the gap between research and market through funding of commercial feasibility assessment studies.

Profile: Researchers with and ERC AdG, CoG, StG or SyGand a breakthrough finding resulting from their ERC research.

Funding: € 150,000

Project duration: up to 18 months

2014: 443 PoC proposals submitted

120 granted (27%)

Next deadline: 16 February 2016

About ERC PoC

ERC PoC

Page 6: ttopstart academy: how to write a successful ERC PoC proposal

BEST PRACTICES

Presented following our FFWD methodology

FIT – FRAMEWORK – WRITE – DEVELOP

Page 7: ttopstart academy: how to write a successful ERC PoC proposal

FIT

It is important to make sure your project fits the ERC PoC progamme, i.e.:

• You are an ERC laureate

• You have a protectable invention that results from your ERC research (preferably a patent application has been filed)

• You have sound preliminary data

• There is clear commercialisation potential

• There is no definitive commercialisation plan yet

Examples include:

New medical devices, new therapies, platform technologies, IVDs, robotic systems, research tools.

ERC PoC best practices - FFWD

ERC PoC

Page 8: ttopstart academy: how to write a successful ERC PoC proposal

FRAMEWORK

The structure of your proposal will help to guide the reviewers, who are typically not familiar with the technology.

• Start from the problem you are addressing and quantify it.

• Present your proposition

i.e. “Our platform will be the first to allow stratification of patients at risk of …” instead of “Our platform is super sensitive”.

• Make sure to balance technological work and commercial feasibility assessment

• Involve business developers (e.g. from your tech transfer office and/or ttopstart)

ERC PoC best practices - FFWD

ERC PoC

Page 9: ttopstart academy: how to write a successful ERC PoC proposal

WRITE

The reviewer will judge your proposal on the feasibility plan, not the underlying science, so there is no need for lengthy scientific descriptions. Furthermore:

• Keep it simple

• Be specific

• Focus on the business case

• Refrain from very generic / high-level market descriptions

such as “The market for stem cells will reach € X bln by 2020”

• Clearly list the steps needed towards market introduction and commercial success

ERC PoC best practices - FFWD

ERC PoC

Page 10: ttopstart academy: how to write a successful ERC PoC proposal

DEVELOP

The ERC PoC is all about commercialisation.

• Illustrate both the short and the long-term impact of the project on e.g. patients, society, industry and/or science

• Make sure you show you understand the market and its challenges

• Include all relevant aspects of commercialisation: IP, possible business / earnings models, route to market, team, market size, regulatory aspects, etc

• Get support letters from industry

• Make sure to include a risk and mitigation plan

• Keep the end-goal in mind: an investor’s case

ERC PoC best practices - FFWD

ERC PoC

Page 11: ttopstart academy: how to write a successful ERC PoC proposal

Dr. Henrique Veiga-FernandesGroup leader at IMM Lisboa,

2013 ERC PoC laureate and now CSO of StemCell2Max

“ttopstart has helped me to:• Write the ERC PoC grant• Perform necessary market

research• Develop a business plan to

attract capital”

Meet one of our clients

Page 12: ttopstart academy: how to write a successful ERC PoC proposal

Prof dr. Raymond SchiffelersProfessor of Nanomedicine at UMCU,

2012 ERC PoC laureate and now CSO of Excytex

“ttopstart has been very helpfulin providing the business perspective for both the

preparation of the ERC PoCproposal as well as the

establishment of Excytex”

Meet one of our clients

Page 13: ttopstart academy: how to write a successful ERC PoC proposal

Interested?

[email protected]

Page 14: ttopstart academy: how to write a successful ERC PoC proposal

The ttopstart team

ERC PoC

Page 15: ttopstart academy: how to write a successful ERC PoC proposal

ttopstart is a science and business consulting company that serves leading researchers and innovative companies in the fields of life sciences and medical technology.

Our excellent track-record (>50% success rate in Horizon 2020; 18 out of 20 ERC PoC grants) is attributable to:

• Our broad technological and scientific knowledge

• Our business development background

• Our in-depth knowledge of subsidy programmes

• Our structured approach

• Our writing skills

About ttopstart

ERC PoC

Page 16: ttopstart academy: how to write a successful ERC PoC proposal

ttopstart offers a balanced set of funding and business development services, all dedicated to biomedicalresearchers and entrepreneurs.

ttopstart services

ERC PoC

Prepare

Funding strategy

Develop

Proposal writing

PRO-ACTIV• Analysis• Customised strategy• Training & Implementation• Valuation

FFWD• Fit• Framework • Write • Develop

Empower your team to excel Reach a 50% success rate

Execute

Project management

• Management• Dissemination• Exploitation

Focus on the science

Exploit

Business development

Page 17: ttopstart academy: how to write a successful ERC PoC proposal

Within ERC PoC, we can:

• Write the grant proposal

• Lead the business development activities

• Perform market research

• Develop a VC-ready business plan

• Develop and implement a funding strategy

We do not:

• Acquire IP or participate as a shareholder

ttopstart services

ERC PoC

Page 18: ttopstart academy: how to write a successful ERC PoC proposal

Check our funding database:

www.ttopstart.com/subsidies/database

Page 19: ttopstart academy: how to write a successful ERC PoC proposal

ttopstart BV

[email protected]

P.C. Staalweg 303721 TJ BilthovenThe Netherlands+31 (0)30 73 70 779

Our services• Subsidies• Business development• Project managementFor life sciences and medical technology

The ttopstart team:Patrick de Boer, MScJochem Bossenbroek, MScir. Jasper LevinkSanne Kuijper, PhDMarije aan den Toorn, PhDFerdinand Los, PhDJean-Pierre Sommeijer, PhDMichelle van Wijk, MScAndrée Schram, PhDGeorgia Xouri, PhDAntoin de Weijer, PhDKarlijn Bastiaansen, PhDKarin Bosch-Elberse, PhDJelle Zijlstra, MScAnouk IJlst, MA