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What is the emkaBATH4 system? Integrated and compact solution for studying the contractile properties of isolated tissue: aortic rings trachea papillary muscles atrium uterus ... The intelligent setup that takes care of technical details so you can concentrate on your data! http://isolated-organ.emka.fr/
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www.emka.fr
smart tools – swift services – sharp
research
emkaBATH4tissue bath system
1 - what is the emkaBATH4 system? APPLICATIONS SYSTEM OVERVIEW
2 - how does it work?AUTOMATIONSTAND-ALONE USE OR SOFTWARE CONTROLDATA ACQUISITIONSTIMULATION
3 - why use it?
what is the emkaBATH4 system?
aortic rings
trachea
papillary muscles
atrium
uterus
...
integrated and compact solution for studying the contractile properties of isolated tissue
www.emka.fr
smart tools – swift services – sharp
research
all-in-one mainframe
• 4 baths with transducers & amplifiers
• bath temperatures adjusted and
controlled electronically
• automated bath filling/emptying
• automated tissue tensioning with
motors
what is the emkaBATH4 system?
www.emka.fr
smart tools – swift services – sharp
research
integrated hardware
• pump for pushing perfusate to baths
• emptying pump for drawing perfusate
from the baths
what is the emkaBATH4 system?
www.emka.fr
smart tools – swift services – sharp
research
integrated hardware
• motors for tissue tensioning
• heating elements
• signal amplifiers
what is the emkaBATH4 system?
www.emka.fr
smart tools – swift services – sharp
research
the emkaBATH4 mainframe comes with:
• a power supply unit
• a perfusate reservoir
• container for used perfusate
what is the emkaBATH4 system?
www.emka.fr
smart tools – swift services – sharp
research
large range of hooks designed to facilitate tissue manipulation
range of bath sizes• 20ml• 10ml • 5ml
what is the emkaBATH4 system?
www.emka.fr
smart tools – swift services – sharp
research
custom-designed it50 isometric transducers
• robustness
• sensitivity
what is the emkaBATH4 system?
www.emka.fr
smart tools – swift services – sharp
research
custom-designed it50 isometric transducers
• stainless steel body
• 0-50 g (0 - 0.5 N) measuring range• displacement: 0.89 mm/50g• sensitivity@Vcc=5V: 0.1 mV/g
what is the emkaBATH4 system?
www.emka.fr
smart tools – swift services – sharp
research
microvessel study
• easily adapted for the study of up to 4 microvessels
• for vessels of diameter 100μm to 3 mm and up to 3.5mm long• each microvessel bath incorporates its own isometric transducer, measuring forces up to 30g
what is the emkaBATH4 system?
www.emka.fr
smart tools – swift services – sharp
research
mainframe control panel provides access to all operations
• set temperature : perfusate is heated to the required temperature as it travels to the bath• calibration : 0-1g / 0-10g / 0-50g
how does it work?
www.emka.fr
smart tools – swift services – sharp
research
mainframe control panel provides access to all operations
• set tension
(automated but manual override always
possible)
• fill, empty bath
• wash, renew bath
how does it work?
www.emka.fr
smart tools – swift services – sharp
research
data acquisition with iox or other data acquisition software
• USB connection to PC running iox software
• information displayed on the control panel is sent to iox (temperature, tissue tension)
• protocols can also be exported from iox
• BNC outputs provide calibrated analog signal to any acquisition system
how does it work?
www.emka.fr
smart tools – swift services – sharp
research
designed for maximum productivity • full data display as graphs, tables, trends
• beat to beat calculation on fast beating tissues
(papillary/atrial muscles)
• detailed calculation on slow contracting tissue (uterus, ileum)
• on-the-fly comment and mark addition
• preprogrammed action triggered by function key or timers
• automated control of stimulators, valves, motors
iox acquisition software
www.emka.fr
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powerful post-processing
• data extraction• group averaging• ED50• ...
datanalyst software
www.emka.fr
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research
electrodes and stimulation• electrodes and stimulators are available from emka TECHNOLOGIES
• third-party stimulators can also be used (iox control is not possible)
how does it work?
www.emka.fr
smart tools – swift services – sharp
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simple to set up and run• completely automated• easy mounting and removal for cleaning• corrosion-resistant • external connections and peripheral devices reduced to a minimum
why use it?
www.emka.fr
smart tools – swift services – sharp
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smart features
open system: analog outputs
electric heating system for baths
• faster response when compared to air heated systems to maintain
temperature control
• more accessible baths when compared with air heated system
why use it?
www.emka.fr
smart tools – swift services – sharp
research
smart features
modular solution design
• customization (i.e. bath sizes, tissue-holder, additional measurements such
as pH, etc.)
• up to 16 simultaneous baths with software control
why use it?
www.emka.fr
smart tools – swift services – sharp
research
smart features
seamless hardware/software integration• all bath operations are accessible from within the acquisition software
• filling/emptying and/or tissue tension operations are all set in the acquisition
protocol
(no need of a separate tissue bath control application)
• quality control: tissue tension, and temperature data recorded
why use it?
www.emka.fr
smart tools – swift services – sharp
research
smart features
fast fill, and empty of baths
pumps for liquid control
overflow-based bath renewal
tissue is never exposed to air: no risk of drying!
easy calibration
why use it?
@emkaTECH
www.facebook.com/emkatechnologies
www.emka.fr
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