Direct enantio-convergent transformation of

racemic substrates without

racemization or symmetrization

Table of Contents

1. THE CHIRAL COMPOUND

– Synthesis or Resolution?

2. BORON CHEMISTRY

– Electrophile or Nucleophile?

3. ARTICLE R&D – Direct Enantio-Convergent

Transformation (DECT)

SUGA/ITOH Lab. Literature Seminar@2o12-06-07

M2 Kaoru ARISUE

Nature Chem. 2010, 2, 972.

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解説記事 月刊化学 有合化

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Kinetic Constant (A vs. B)

Calcd: kA/kB 98.4 : 1.6

Exptl: er 99.5 : 0.5

Kinetic Constant (C vs. D)

Calcd: kC/kD 91 : 9

Exptl: er 94 : 6

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