Mast cells release histamine

Mast cells release

histamine

Bacterial invaders attack

Capillaries dilate Phagocytes

Attack

InflammatoryResponse

•Swelling•Fever•Redness

Splinter breaks through

skinbacteria enters

Bone

Marrow

Found in tissues Found in blood

Blood vessel

Epidermis

Dermis and tissue

Thymus

Gland

2

2 2

1 3 2 1 2

2 32 2 3

FirstLineOf

Defense

Skin MucusLining

In

RespiratoryTract

LeucocytesAttack

Second Line of

Defense

Third Lineof

Defense

Respiratory Tract lined With Cilia

Keeping invaders out of lungs

LysozymeAntimicrobialSubstance

Contained in Mucous

Membranes

1 2

2 2

11 11 2

1 2 1 22 2

MEMORYB-cells

Macrophage Dendritic Cells

Eosinophils

Neutrophils Lymphocytes Monocytes Basophils

B-Cells and T-Cells20 – 35 % in blood50-70% in blood 1-6% in blood

Phagocytes or Macrophages

< .5 % in bloodUsually sent to tissues

and become mast cells

1 -3 % in blood

1 3 1 3 2 3 1 1

1 11 3 1 1 1 3

Complement System

Interferons NaturalKillerCells

ProteinSubstanceReleased

To neighboring

cell

CancerCells

MEMORYHelper T-cells

Decrease of

pathogengrowth

Protection

Against

Viral

Invasion

3 3 3 3 2 2 2

2 2 1 32 3

B - Cells Bacterial invaders attack

CytotoxicT-Cells

Macrophage&

HelperT-Cell

Cocci

Virus infected

BodyCells

Antigen Presenting Body Cells

Body Cells infected

Lymph

NodesMovesTo…

2 3 1 3 1 3 1 3

1 11 3 2 1 2

Interleukin - 1 Bacterial invaders attack

FungalInvader

Interleukin - 2&

Other cytokinesVirusInvader Virus

InvaderVirusInvader

Bacterial invaders attack

Bacillis Spirochete

RotavirusBasic capsid Adenovirus

Candida albicans

1 3

1 3 1 3 1 3

2

2

1 3 1 3

Fever Parasitic invaders attack

101 o F

Giardia intestinal protozoan parasites

Non-

Specific

Response

Specific

Response

MajorHistocompatibility

Complex

MHC

Self Cell

MHC Recognition marker

Increase rate of

production and activity

of phagocytes

Leucocytes release

pyrogens&

FeverBegins

1 32 2 1 3 1

1 1 1 1 2 21

B-Cell Joker

T-CellJoker

Antimicrobial

Proteins

Plasma Cells Antibodies Helper T-cells

Virus

Cell

Lysis

Influenza

1 1 1 1 1 3 1 2

1 3 3 4 2 32 2