医療･バイオ分野への RF CMOS回路技術RF CMOS Circuits for Medical and Biological Applications

統合研究院 益研究室Integrated Research Institute, Masu GroupMasu Group

Tokyo Tech

目的,Purpose ﾊｲﾗｲﾄ,Highlights

詳細技術,Details

ワイヤレス医療･バイオ通信システムの実現

　・ボディエリアネットワーク通信用　　　　　　　 低電力RF CMOS回路設計技術　・センサとの統合化CMOS回路設計技術　・生体情報の収集、管理蓄積技術

Wireless medical and biological communication systems・Low power RF CMOS circuit design・CMOS circuit design with sensors・Management system for in vivo data

バッテリーレス in vivo 無線通信回路技術

・電磁結合によるエネルギーと信号の伝送・パルスインターバル無線変復調回路・医療・バイオセンサ(pHや温度など）　　　　　　とのインターフェース回路Batteryless in vivo wireless 　　　　　　　　communication circuit・Energy and signal transmission using magnetic coupling ・Pulse Interval Modulation (PIM)・Interface circuit for medical and biological sensors, pH and temperature

Transceiver

Magnetic flux

ReceiverAntenna

Antenna電力と信号の伝送

ISM

ISM39 dB35 MHz

54 dB3.5 MHz47 dB13 MHz

90 dB2.45 GHz

51 dB1 MHz45 dB300 kHz

AttenuationFrequency

39 dB35 MHz

54 dB3.5 MHz47 dB13 MHz

90 dB2.45 GHz

51 dB1 MHz45 dB300 kHz

AttenuationFrequency

T. Yamada, Japanese Journal of Applied Physics, 2005

Signal loss of human body model (15cm depth)

Magnetic coupling

ワイヤレス医療・バイオ通信システム

パルスインターバル変調

t

Voltage

data

two pulses

△O△Bit rate

O×OPowerconsumption

OO×Attenuation

PIM*FSKPSKASKModulation

△O△Bit rate

O×OPowerconsumption

OOAttenuation

PIM*FSKPSKASKModulation

T. Yamada, Japanese Journal of Applied Physics, 2005

・Strong for signal losses・Low power operation without OSC・Low frequency pulse

提案する通信回路の構成

ISFETを用いたpHセンサ回路

Simulation

60 mV/pH

ISFET Vth (V)

7 141

Out

put v

olta

ge (V

)

-1 0 1

0

-1

-1 .8

pH

Vth is changed by pH

ISFET

O P

Ｖｄｄ

Vin

Vout=Vin

Vth+Vout(Vin)

Source follower type pH sensor circuit

+

Base station frequency:13.56MHｚ sine wave Simulated by ADS

(1)pH2

2.58V 2.33V

58.5µs

Time (msec)

Vint

erna

l (V

)

(2)pH3

2.53V 2.20V

67.2µs Vint

erna

l (V

)

Time (msec)

Communication circuit

M9

21 9

Vinternal

Primary pulse generator circuit

Secondary pulse generator circuit

inverters

Power supply circuit

M1

123

M4M3

M2

M8M7

M6

C1

C2

C3Va Vb

Vout

inverters1

2

pH sensor circuit

pH s

enso

r

M5 M11

M10

8

8B

A

DC

Bas

e st

atio

n

Simulation results

WirelessLAN

TX/RX

Wrist

Repeater

Implant

In mouse

Capsule

ADCWireless

LANLSI

Demod ADC

Power

B

LAN interface

PA

LNASignal

Repeater

Sensor RFMod.

Powersupply

Battery less sensor module

LAN

Data Base

Temp.PressurepH

ISFET: Ion Sensitive Field Effect Transistor

http://www.masu-lab.com/