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11 April 1975 Volume 188, No. 4184 SI- - - - - : 0 50if . , . -f. ^ f , - LETTERS The Ethics of Experimentation: A. R. Jon.tsen; P. Lowinger; Inefficient Medical Care: S. Raymtiond; Honeybee Controversy: R. Rosin; Political Decision: A. Shapiro ........................................ EDITORIAL Coercive Power of the Federal Purse: K. Brewster ........................ ARTICLES Evolution at Two Levels in Humans and Chimpanzees: M.-C. King and A. C. Wilson. . Stratospheric Ozone Dest,ruction by Aircraft-Induced Nitrogen Oxides: F. N. Alyea, D. M. Cunnold, R. G. Prinn ........................... Technology Observed: Attitudes of a Wary Public: T. R. La Porte and D. Metlay ................................................ NEWS AND COMMENT RESEARCH NEWS BOOK REVIEWS Iran: Trying to Buy Academic Parity with the West ....................... Beyond Vladivostok: The Feasibility and the Politics of Arms Reductions ........ Intensive Care for Newborns: Are There Times to Pull the Plug? ............... Offshore Oil: Supreme Court Ruling Intensifies Debate ....................... Energy: Washington Gets a New Proposal for Using H-Bombs ............... Hepatitis B: A New Vaccine Ready for Human Testing. ................... 105 107 117 121 128 130 133 135 136 137 Sex and Evolution, reviewed by E. 0. Wilson: DNA Synthesis, R. D. Wells; Gene Expression, G. Wilcox; Topics in Carbon-13 NMR Spectroscopy, J. A. Magnuison; Amorphous and Liquid Semiconductors, D. Adler; Water and Aqueous Solutions, D. Eisenberg; The Major Ternary Structural Families, A. Wold; Books Received ............................... 139 BOARD OF DIRECTORS ROGER REVELLE MARGARET MEAD WILLIAM D. MC ELROY RICHARD H. BOLT EMILIO Q. DADIARIO Retiring President. Chairman President President-Elect KENNETH B. CLARK EDWARD E. DAVID, JR CHAIRMEN AND MATHEMATICS (A) PHYSICS (B) CHEMISTRY (C) ASTRONOMY (D) SECRETARIES OF Victor L. Klee Victor F. Weisskopf William E. Hanford Carl Sagan Truman A. Botts Rolf M. Sinclair Leo Schubert Arlo U. Landolt AAA$ SECTIONS PSYCHOLOGY (J) SOCIAL AND ECONOMIC SCIENCES (K) HISTORY AND PHILOSOPHY OF SCIENCE (L) ENGINEERING Richard C. Atkinson Seymour M. Lipset Roger C. B:uck Edward Wenk, Jr Edwin P. Hollander Daniel Rich George Basalla Paul H. Robbins EDUCATION (Q) DENTISTRY (R) PHARMACEUTICAL SCIENCES (S) INFORMATION, COMPUTING, AND COMMUNICAT F. James Rutherford Clifton 0. Dummett James T. Doluisio Martin Greenberger Phillip R. Fordyce Sholom Pearlman Raymond Jang Joseph Becker DIVISIONS AlASKA DIVISION PACIFIC DIVISION SOUTHWESTERN AND ROCKY MOUNTAIN Dll William E. Davis Irma Duncan George A. Zentmyor Robert T. Orr Joseph A. Schufie Max P. Dunford Chairman, Executive Committee Executive Secretary President Secretary-Treasurer President Executive Officer SCIENCE is published wek, except the lst week In Doomber, but with an etr issue on the fourth Tuesday in November, by the Am a Aocitin for the Advenement ol Scienc, 1515 Masschuset Ave., NW, Washino, D.C. 20005. New ombInd with The Scientic -onthly' Second-class postage paid at Washington, D.C. Copyright § 1975 In the American Association for the Advancement of Science. Member rtes on request. Annual subsaription $40; foreign postge: Americas $6, overseas $8, air lift to Europe $20 Single copies $1 (back issues $2) except Gi to Scientlfic lnstrm ts which is $4. School year subscription: 9 months $30; 10 months $33.50. Prices for subcriptions receve after I May 1975 will be $50; foreign postage: Americas $7, overseas $8, air lift to Europe $30. These prices are now in effect for renewals of subscriptions expiring on or afts 25 April 1975. Provide 6 weeks notice for change of address, giving new and old address and zip codes. Send a recent address label. Scince Is Indexed In th Reader's Guide t PerioiclUterte. 98 on July 11, 2018 http://science.sciencemag.org/ Downloaded from

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11 April 1975Volume 188, No. 4184

SI-- - - - : 050if

. , . -f. ^ f , -

LETTERS The Ethics of Experimentation: A. R. Jon.tsen; P. Lowinger; InefficientMedical Care: S. Raymtiond; Honeybee Controversy: R. Rosin;Political Decision: A. Shapiro ........................................

EDITORIAL Coercive Power of the Federal Purse: K. Brewster ........................

ARTICLES Evolution at Two Levels in Humans and Chimpanzees: M.-C. King and A. C. Wilson. .

Stratospheric Ozone Dest,ruction by Aircraft-Induced Nitrogen Oxides:F. N. Alyea, D. M. Cunnold, R. G. Prinn ...........................

Technology Observed: Attitudes of a Wary Public: T. R. La Porte andD. Metlay ................................................

NEWS AND COMMENT

RESEARCH NEWS

BOOK REVIEWS

Iran: Trying to Buy Academic Parity with the West .......................Beyond Vladivostok: The Feasibility and the Politics of Arms Reductions ........Intensive Care for Newborns: Are There Times to Pull the Plug? ...............Offshore Oil: Supreme Court Ruling Intensifies Debate .......................

Energy: Washington Gets a New Proposal for Using H-Bombs ...............Hepatitis B: A New Vaccine Ready for Human Testing....................

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Sex and Evolution, reviewed by E. 0. Wilson: DNA Synthesis, R. D. Wells;Gene Expression, G. Wilcox; Topics in Carbon-13 NMR Spectroscopy,J. A. Magnuison; Amorphous and Liquid Semiconductors, D. Adler;Water and Aqueous Solutions, D. Eisenberg; The Major TernaryStructural Families, A. Wold; Books Received ............................... 139

BOARD OF DIRECTORS ROGER REVELLE MARGARET MEAD WILLIAM D. MC ELROY RICHARD H. BOLT EMILIO Q. DADIARIORetiring President. Chairman President President-Elect KENNETH B. CLARK EDWARD E. DAVID, JR

CHAIRMEN AND MATHEMATICS (A) PHYSICS (B) CHEMISTRY (C) ASTRONOMY (D)SECRETARIES OF Victor L. Klee Victor F. Weisskopf William E. Hanford Carl SaganTruman A. Botts Rolf M. Sinclair Leo Schubert Arlo U. Landolt

AAA$ SECTIONSPSYCHOLOGY (J) SOCIAL AND ECONOMIC SCIENCES (K) HISTORY AND PHILOSOPHY OF SCIENCE (L) ENGINEERINGRichard C. Atkinson Seymour M. Lipset Roger C. B:uck Edward Wenk, JrEdwin P. Hollander Daniel Rich George Basalla Paul H. Robbins

EDUCATION (Q) DENTISTRY (R) PHARMACEUTICAL SCIENCES (S) INFORMATION, COMPUTING, AND COMMUNICATF. James Rutherford Clifton 0. Dummett James T. Doluisio Martin GreenbergerPhillip R. Fordyce Sholom Pearlman Raymond Jang Joseph Becker

DIVISIONS AlASKA DIVISION PACIFIC DIVISION SOUTHWESTERN AND ROCKY MOUNTAIN DllWilliam E. Davis Irma Duncan George A. Zentmyor Robert T. Orr Joseph A. Schufie Max P. DunfordChairman, Executive Committee Executive Secretary President Secretary-Treasurer President Executive Officer

SCIENCE is published wek, except the lst week In Doomber, but with an etr issue on the fourth Tuesday in November, by the Am a Aocitin for the Advenement olScienc, 1515 Masschuset Ave., NW, Washino, D.C. 20005. New ombInd with The Scientic -onthly' Second-class postage paid at Washington, D.C. Copyright § 1975 Inthe American Association for the Advancement of Science. Member rtes on request. Annual subsaription $40; foreign postge: Americas $6, overseas $8, air lift to Europe $20Single copies $1 (back issues $2) except Gi to Scientlfic lnstrm ts which is $4. School year subscription: 9 months $30; 10 months $33.50. Prices for subcriptions receveafter I May 1975 will be $50; foreign postage: Americas $7, overseas $8, air lift to Europe $30. These prices are now in effect for renewals of subscriptions expiring on or afts25 April 1975. Provide 6 weeks notice for change of address, giving new and old address and zip codes. Send a recent address label. Scince Is Indexed In th Reader's Guide tPerioiclUterte.

98

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AMERICAN ASSOCIATION FOR THE ADVANCXEMNT Or SCIENCE

REPORTS Vaporization of Solids: Evidence for a Zipper Mechanism in the RetardedVaporization of Arsenic: C. A. Hiiltma(n and G. M. Rosenblatt .................145

Laurentide Ice Sheet Meltwater Recorded in Gulf of Mexico Deep-Sea Cores:J. P. Ken1nett and N. J. Shackletoni .. ...................................... 147

Submarine Barite-Opal Rocks of Hydrothermal Origin: K. K. Bertine andJ. B. Keene .............................................. 150

Electron Spin Resonance for Detecting Polyadenylate Tracts in RNA's:A. M. Bobst, 7. K. Sinha, Y.-C. E. Pan ...................................153

Light-Induced Changes in the Structure of Pigmented Granules in AplysiaNeurons: M. Henkart ......................................... 155

PhototransduCtion in Aplvsia Neurons: Calcium Release from PigmentedGranules Is Essential: A. M. Brown, P. S. Bair, Jr., F. H. Tiley, Jr.............157

Partial Amino Acid Sequence of the Precursor of Immunoglobulin Light ChainProgrammed by Messenger RNA in vitro: 1. Schechier et al ............... 160

Solar Nitrogen: Evidence for a Secular Increase in the Ratio of Nitrogen-15to Nitrogen-14: J. F. Kerridge ............................................ 162

Yeast Chromatin SuLbullit Structure: D. Lohr and K. E. Vani Holde ................... 165

Fever and Survival: M. J. Kliuger, D. H. Rinigler, M. R. Aner ..................... 166

Techniiccal Co0mminen1ts: HeLa Cells and RT4 Cells: L. M. Franks and C. Rigby;W. A. Nelson-Ree.s ........................................... 168

Trace Metals Analyzer; Dilutor-Dispenser: Spectrophotometer Calibration;Electronic Balance; Universal Test Stand; Colorimeter; Nuclear MagneticResonance Spectrometer; Still; Recorder-Logger; Fraction Collector;Literature. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

RUTH M. DAVIS FREDERICK MOSTELLER WILLIAM T. GOLDEN WILLIAM D. CAREYWARD H. GOODENOUGI CHAUNCEY STARR Treasurer Executive Officer

GEOLOGY AND GEOGRAPHY (E) BIOLOGICAL SCIENCES (G) ANTHROPOLOGY (H)William E. Benson Hans Laufhr Ruth L. BunzelRalnon E. Bisque Jane C. Kaltenbach Philleo NashMEDICAL SCIENCES (N) AGRICULTURE (0) INDUSTRIAL SCIENCE (P)Robert Austrian Paul E. Waggoner Jordan D. LewisRichard J. Johns J. Lawrence Apple Robert L. SternSTATISTICS (U) ATMOSPHERIC AND HYDROSPHERIC GENERAL 00Carl A. Bennett SCIENCES (W) Athelstan F. SpilhausEzra Glaser Charles E. Andeon Joseph F. Coates

Stanley A. Changnon, Jr.

TA Amnerican A oleon fr the Advacment of Science was founde in 1848 and incrated in1874. Its o*ca to futhe the work of scientist, to failitab coopertion amog them, toImr the of :scIe In th pom*oto of human welfar- and to Icease pubi unde.sandI eiation a ise of the mebtod of semno In humn roges.t tr Sd Fm 3547 t SCIENCE, 1515 M Avenue, NW, Washington, D.C. 20005.

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Chimpanzee (Pan troglodytes troglo-dytes). Although chimpanzees differsubstantially from humans in anatomyand way of life, the proteins and DNAof the two species differ no more thando those of sibling species. See page107 [Part la of plate It by PierreDandelot, Paris Museum of NaturalHistory; from A Field Guide to theLarger Manmmals of Africa by JeanDorst, Houghton Mifflin Company,19701

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