176

ductive substrate of conductive carbon or the like is covered with an oxygen-reducing catalytic function layer and enzyme layer. Thus, there is no problem of contamination of enzyme sensor, and it is possible to readily manufacture and miniaturize enzyme sensors.

5205935

H I G H P E R F O R M A N C E F I X E D F I L M B I O R E A C T O R

Joseph J Ruocco assigned to AAA Environ- mental Services Corp

A method and apparatus for the continuous degradation of hazardous paint and organic sol- vent wastes. The apparatus includes a high per- formance fixed film bioreactor system into which is fed waters contaminated with paints or solvents from industrial operations and which utilizes the characteristic of either anaerobic or aerobic microorganisms growing on a fixed film for the degradation of these solvents and purification of contaminated waters. The bio- reactor incorporates novel internal flow features which result in highly effective destruction of or- ganic wastes in aqueous streams.

5206135

U S E O F T H E O X Y G E N A S E A C T I V I T Y O F A C E T O L A C T A T E

S Y N T H A S E F O R H E R B I C I D E D E T E C T I O N

Lynn M Abell, John V Schloss assigned to E I Du Pont de Nemours and Company

A process for the detection of herbicides that in- hibit acetolactate synthase (EC 4.1.3.18) by use of the enzyme, a suitable substrate (pyruvate, alpha-aceto-lactate, alpha-ketobutyrate, or alpha-aceto- alpha-hydroxybutyrate), and an oxygen-sensitive electrode is disclosed.

5206136

R A P I D M E M B R A N E A F F I N I T Y C O N C E N T R A T I O N A S S A Y S

Nobu Monji, Carol-Ann Cole assigned to Gene- tic Systems Corporation

PATENT ABSTRACTS

Rapid assays for analytes of interest in a fluid sample utilize a first conjugate of a labelled reac- tant that specifically binds to the analyte, and a second conjugate that binds to the analyte coupled to a polymer that has an affinity for a selected solid phase. The reaction components are incubated briefly, then contacted with the selected solid phase and the labelled components determined. Optional wash steps provide for en- hanced sensitivity and specificity. When the ana- lyte of interest is an antibody to HIV, the first reactant may be a synthetic, recombinant or na- tive H1V antigen, and the second reactant may be protein A or an anti-immunoglobulin.

5206137

C O M P O S I T I O N S A N D M E T H O D S U S E F U L F O R G E N E T I C

A N A L Y S I S

Nancy Y Ip, Howard J Baum assigned to Lifecodes Corporation

A method for obtaining polynucleotide sequences which are useful for detecting Variable Tandem Repeat polymorphism at multiple genetic loci and other genetic analyses under high stringency conditions (hence, with high specificity) is herein disclosed. Also dis- closed are polynucleotide sequences and other compositions useful for DNA polymorphism and other genetic analyses.

5206139

M E T H O D F O R D E T E R M I N I N G T H E P R E S E N C E O R

C O N C E N T R A T I O N O F A B O U N D E N Z Y M E

N Rober Ward, Philip J Lozier assigned to Bio- Control Systems Inc

There is disclosed a process and a device for detecting and measuring (1) the amount of en- zyme present as a detecting system following a nucleic acid hybridization reaction or immuno- reaction; (2) the level and activity of free enzyme in a biological sample; (3) the level of enzyme from contaminating microorganisms present in a sample; and (4) enzymes from pure culture isolates for microbial identification and anti- microbial susceptibility testing.