410 Book Reviews Werk, R.: Medizinische Bakteriologie und Infektiologie. Basiswissen und Diagnostik. (Med- ical Bacteriology and Infectiology. Basic Knowledge and Diagnostics). XV, 370 pages, 62 figures, 244 tables. Springer-Verlag, Berlin-Heidelberg-New York 1990. Soft cover DM 78.- The booklet furnishes a very good survey of basic microbiology, with regard to medical microbiological laboratories, including matters of sterilization, agar cultures and deficiencies in their production. It outlines the methods of working up clinical material and in vitro testing of chemotherapeutics. - In the chapter entitled "Working up of clinical material", the needs of the clinician are well outlined. The various correct techniques for taking samples, e.g. for preparing blood cultures, urine cultures and smears as well as for carrying out punctures are described. Furthermore, the spectra of the specific infectious agents with their frequency of occurrence are dealt with. The important nosocomial infections are described in detail within the relevant chapters. - The booklet is of great interest to clinicians, though the stress is rather laid on microbiology and not on clinical infectiology. M. Alexander (Berlin) (59/91) Wadstrom, T., I. Eliasson, I. Holder, and A. Ljungh (Eds.): Pathogenesis of Wound and Biomaterial-Associated Infections. 570 pages, 116 figures. Springer-Verlag, London-Ber- lin-Heidelberg-New York 1990. Soft cover DM 148.- This book has been written by numerous authors and covers the subjects of theoretical foundations of wound infections, the agents involved and their action on the human body. Opportunistic agents are included and particular reference is made to infections in relation to prosthetic devices (e.g. artificial heart valves and pelvic joints). The descriptions in the individual chapters are largely based on animals experiments and in vitro models. The book is based on a symposium which united microbiologists, immunologists and cell biologists as well as clinicians, in particular from surgical disciplines, to create an international platform for discussions of the subject of natural and experimental wound infections, in particular those resulting from burns and incorporation of artificial materials. The discussions have produced important knowledge regarding the cell surface determinants of microorganisms, extracellular and bacterial enzymes and toxins, spreading of infections and their prevention by methods of immunoprophylaxis and the development of new antibiotics. M. Alexander (Berlin) (60/91) Hoffman, S. L. and L.}. Martinez (Eds.): Malaria Vaccine Development. Pre-Erythrocytic Stages. Proceedings of a Conference held in the National Naval Medical Center, Bethesda, Maryland, USA, 12-15 April 1989. (Supplement to Vol. 68 of the Bulletin of the World Health Organization). 196 pages, illustrated. World Health Organization, Geneva 1990. Soft cover SFr. 35.-, US $ 31.50 In 1979, a conference was held in Bethesda, Maryland, USA, to establish the situation with regard to the development of an antimalarial vaccine. Since then, essential progress has been made by applying techniques of molecular biology and new immunological methods. Thus, it was justified to hold another symposium ten years later. At that symposium, scientists from all over the world presented reports on their results with regard to the production of a vaccine against sporozoites and the stages of the parasite found in the liver.

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410 Book Reviews

Werk, R.: Medizinische Bakteriologie und Infektiologie. Basiswissen und Diagnostik. (Medical Bacteriology and Infectiology. Basic Knowledge and Diagnostics). XV, 370 pages, 62 figures, 244 tables. Springer-Verlag, Berlin-Heidelberg-New York 1990. Soft cover DM 78.-

The booklet furnishes a very good survey of basic microbiology, with regard to medical microbiological laboratories, including matters of sterilization, agar cultures and deficiencies in their production. It outlines the methods of working up clinical material and in vitro testing of chemotherapeutics. - In the chapter entitled "Working up of clinical material", the needs of the clinician are well outlined. The various correct techniques for taking samples, e.g. for preparing blood cultures, urine cultures and smears as well as for carrying out punctures are described. Furthermore, the spectra of the specific infectious agents with their frequency of occurrence are dealt with. The important nosocomial infections are described in detail within the relevant chapters. - The booklet is of great interest to clinicians, though the stress is rather laid on microbiology and not on clinical infectiology.

M. Alexander (Berlin) (59/91)

Wadstrom, T., I. Eliasson, I. Holder, and A. Ljungh (Eds.): Pathogenesis of Wound and Biomaterial-Associated Infections. 570 pages, 116 figures. Springer-Verlag, London-Berlin-Heidelberg-New York 1990. Soft cover DM 148.-

This book has been written by numerous authors and covers the subjects of theoretical foundations of wound infections, the agents involved and their action on the human body. Opportunistic agents are included and particular reference is made to infections in relation to prosthetic devices (e.g. artificial heart valves and pelvic joints). The descriptions in the individual chapters are largely based on animals experiments and in vitro models. The book is based on a symposium which united microbiologists, immunologists and cell biologists as well as clinicians, in particular from surgical disciplines, to create an international platform for discussions of the subject of natural and experimental wound infections, in particular those resulting from burns and incorporation of artificial materials. The discussions have produced important knowledge regarding the cell surface determinants of microorganisms, extracellular and bacterial enzymes and toxins, spreading of infections and their prevention by methods of immunoprophylaxis and the development of new antibiotics.

M. Alexander (Berlin) (60/91)

Hoffman, S. L. and L.}. Martinez (Eds.): Malaria Vaccine Development. Pre-Erythrocytic Stages. Proceedings of a Conference held in the National Naval Medical Center, Bethesda, Maryland, USA, 12-15 April 1989. (Supplement to Vol. 68 of the Bulletin of the World Health Organization). 196 pages, illustrated. World Health Organization, Geneva 1990. Soft cover SFr. 35.-, US $ 31.50

In 1979, a conference was held in Bethesda, Maryland, USA, to establish the situation with regard to the development of an antimalarial vaccine. Since then, essential progress has been made by applying techniques of molecular biology and new immunological methods. Thus, it was justified to hold another symposium ten years later. At that symposium, scientists from all over the world presented reports on their results with regard to the production of a vaccine against sporozoites and the stages of the parasite found in the liver.