A WIRELESS- IMPLANTABLE MICRO SYSTEM FOR CONTINUES BLOOD GLUCOSE MONITORING

ANOOP PRoll No:07Reg. No:CTAHEEC013

ABSTRACT

• Remotely powered implantable micro system • Consists of a micro fabricated glucose

biosensor flip-chip bonded to a transponder chip

• Transponder chip measures the output signal of the glucose biosensor and transmits to the external reader

• Chip can measure the sensor output current ranging from 1 nA to 1 A

LITERATURE SURVEY

1. NON-CONTINOUS BLOOD GLUCOSE MONITORING • Consist of a blood glucose meters• small drop of blood is needed to place on

test strip

LITERATURE SURVEY

2. Continues wired blood glucose monitoring• Used conventional electrochemical glucose

sensors• Large sizes• Wired

DESIGN

DESIGN

• Microfabricating the glucose sensor• Inegrating all the interfacing circuits into a

integral chip(TRANSPONDER CHIP)• Attaching the microfabricated glucose sensor

to the transponder chip using flip chip bonding

SYSTEM OVERVIEW AND FUNCTIONING

SYSTEM OVERVIEW AND FUNCTIONING

• Monitoring system consisting of an implantable microsystem and an external reader.

• Microsystem measures the blood glucose concentration and transmits the measured data to the external reader

GLUCOSE SENSOR

• Amperometric electrochemical biosensor• Consists of three electrodes: 1)a working electrode(WE) 2)a reference electrode(RE) 3)a counter electrode(CE)

ELECTRODES

1. WORKING ELECTRODE• Act as a surface on which the electrochemical

reaction takes place between the glucose and an enzymatic layer

• It catalyzes the oxidation of glucose to gluconic acid

ELECTRODES

2. REFERENCE ELECTRODE• The reference electrode is used to measure the

solution (blood or interstitial fluid) potential

ELECTRODES

3. COUNTER ELECTRODE• An inert conductor (gold) that supplies the current

required for the electrochemical reaction

TRANSPONDER CHIP

1. RF FRONT-END BLOCK

TRANSPONDER CHIP

2. DATA-ACQUISITION

EXTERNAL READER

ADVANTAGES

• Small size of the implant• No need of oxygen• Use of passive telemetry link

CONCLUSION

• Miniaturization procedure for a wireless-implantable microsystem for continuous blood glucose monitoring

• Low cost procedure• Microsystem implanted just underneath the

skin

REFERENCES

• IEEE Trans.Biomed. Eng., vol. 35, no. 7, pp. 526–532, Jul. 1988.

• IEEE Trans. Biomed.Eng., vol. 41, no. 10, pp. 937–942, Oct. 1994.

• Biosensors Bioelectron., vol. 10, pp. 485–494, 1995

THANK YOU