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    MERGER

    CASE STUDY

    OF

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    Status: May 2007

    Contents

    Overview of Sanofi and Aventis

    The Deal

    Why Merger???

    The Sanofi Aventis Merger

    Aventis perfomance

    Sanofi Aventis combined perfomance

    Present scenario

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    Sanofi-Synthlabo a Paris-based pharmaceutical company

    formed in 1999

    Formed when Sanofi(former subsidiary of Total) mergedwith Synthlabo(former subsidiary of L'Oral)

    Pharma giant with sales of $5.6 billion employing 29,200 people

    Product portfolio includes healthcare, pharmaceuticals and cosmetics

    Focus on pharmaceuticals business

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    AVENTIS

    Aventis a pharmaceutical and lab assay testing company formed in

    1999

    Formed when Rhne-Poulenc S.A. merged with Hoechst AG

    The merged company was based in Strasbourg, France

    Product portfolio of Aventis includes medicines in the area of cardiovasculardisease, thrombosis, diabetes, bone disease, epilepsy and cancer.

    20 research centres in three continents

    R&D budget of about 4 billion Euros.

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    THE DEAL

    Sanofi Synthelabo announced plans in early 2004.

    Hostile Take over Bid

    Relaunching of Friendly bid in place of rejected bid

    Aventis approached Swiss drugs giant Novartis

    Intervention of French government

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    Why Merger????

    Ethical sales in excess of $24 billion (19.1bn)

    Record year-on-year growth

    Compete with the likes of Pfizer and GlaxoSmithKline

    Operate in seven therapy areas

    Size and depth of combined portfolio

    European Headquarters

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    sanofi-aventisIntegration process and

    business performance

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    Agenda

    1

    2

    Outline of the integration project

    The key success factors

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    Sanofi-aventis integration: 12 months fromthe announcement to combined operations

    Jan

    April

    June

    July

    Aug

    Sept

    Oct.

    Dec

    Jan 26: Announcement of Sanofi-Synthelabo bid

    April 25: Aventis supervisory board recommends improved offer to stakeholders

    Aug 20: Birth of Sanofi-Aventis: SaSy takes control of Aventis

    July 29: FTC clears Sanofi-Synthelabos offer for Aventis shares

    April 24: Decision to increase price

    Aug 23: Executive committee nominations

    Sep.6: General manager nomination

    Sep.23: Affiliate management committee nomination

    Sep 30: First consolidation of Aventis sales into sanofi-aventis

    June 21 Draft structure of future Management Committee announced

    Oct 15: Choice of country headquarters announced in major countries

    Dec 13: Merger approved by extraordinary Aventis shareholder meeting

    Sep.16: Final results announced: SaSy holds 98,03% of Aventis capital

    Dec 23: Merger approved by extraordinary SaSy shareholder meeting

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    The Company worldwide

    one of the worlds leading pharmaceutical companies

    100,000 employees in the service of health

    More than 17,000 researchers (including Sanofi Pasteur)

    Present in over 80 countries

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    More than 80 locations worldwide

    * 86 IA locations28 R&D locations

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    Sanofi-Aventis combined performance

    million Q1 2009 Q2 2009 Q3 2009 Q4 2009 2009 % Change(vs. 2008)

    Pharmaceuticals

    6,480 6,726 6,354 6,263 25,823 +3.7%

    Vaccines 627 712 1,046 1,098 3,483 +19.2%

    Total sales 7,107 7,438 7,400 7,361 29,306 +5.3%

    Europe 2,948 3,079 3,050 2,982 12,059 +3.2%

    United States 2,295 2,438 2,441 2,252 9,426 +2.8%

    Othercountries

    1,864 1,921 1,909 2,127 7,821 +12.1%

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    Detail of Vaccines 2009 net sales

    Vaccines (in

    million)

    Q1 2009 Q2 2009 Q3 2009 Q4 2009 2009 % Change

    (vs. 2008)

    Polio/Pertussis/Hi

    b

    (incl. Pentacel

    and Pentaxim)

    236 259 229 244 968 +22.8%

    Influenza

    (incl. Vaxigrip

    and Fluzone)

    63 57 378 564 1,062 +46.7%

    of which

    seasonal vaccines

    - - - 202 597 -1.7%

    of which

    pandemic

    vaccines

    - - - 362 465 -

    Meningitis/Pneum

    onia

    (incl. Menactra)

    116 143 205 74 538 +6.1%

    Adult Boosters

    (incl. Adacel)

    96 106 109 95 406 -3.0%

    Travel & Other

    Endemics

    77 88 72 76 313 0.0%

    Other vaccines 39 59 53 45 196 +6.8%

    Total Vaccines 627 712 1,046 1,098 3,483 +19.2%

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    ConsumerHealth Care

    378 311 356 405 1,430 +26.8%

    Generics 93 284 302 333 1,012 +198.0%

    TotalPharmaceuticals

    6,480 6,726 6,354 6,263 25,823 +3.7%

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    The strategic rational of this project

    Creating a platform for strong, sustainable profitable growth

    Accelerate expected sales growth by applying a product and

    country specific strategy

    Leverage marketing and sales forces to launch key productssuccessfully

    Accelerate R&D by focusing combined resources on the most

    promising projects

    Improve profitability through a strategy based on rapid growth

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    Group level integration committee withdecentralized teams in each function

    Integration project chaired by very senior leaders of the two legacy companies

    Decentralized Integration teams within each function (R&D, Industrial, Operations,

    Finance, HR, etc.)

    Integration officers from both legacy companies at each level of the organization toensure highly efficient coordination

    Project structure and timelines adapted to the needs of each function

    Regular reporting of project advancement in each function to the Group IOs and

    exchange of experience between functions

    Corporate communications

    Internal initiatives: Fil Bleu, Chat with President, Communications kit, townhall

    meetings

    External : Corporate web site, Company name & logo, Doctors brochure

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    The key success factors

    StrategyA strong strategic vision and full commitment of the organization to achieve itA proactive approach (unsolicited takeover) to ensure clear decisions and speed inthe entire processBusiness drive throughout the integration process

    LeadershipConstructive interactions with unions & social partnersOne line of command nominated very early in the processStrong visibility of charismatic leadersRapid decisions regarding sites and infrastructure in view of cost optimizationClearly defined rules of the game

    Project managementSolid project preparation with a small core team

    A decentralized project structure with integration officers at all levelTight planning and an ambitious targetSimple milestones shared throughout Pharmaceutical OperationsFocus of operational management on the business

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    Business drive throughout the integrationprocess

    Business oriented integration principlesTop line growthMinimize business disruptionPrioritization of tasks according to business needsRapid decisions on all strategic integration mattersIdentification of quick wins

    No small products (Base Business), No small markets

    Very early understanding of stand alone business context of allaffiliates on both sides through Country Exchange Meetings in June

    Integrated view of the business based on early combined budgetreviews (Nov 04):

    Definition of business objectives from combined operations perspectiveMonitoring of aggressive Top Line growth expectationsReview and challenge of Synergies targetsEnsure preparation for going live from January 1st

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    Constructive interactions with unions &social partners

    Sanofi-aventis believes in the need to have strong partners

    and in a constructive dialogue with them

    Very early in the process JF Dehecq and country

    management met the union representatives of both legacycompanies before any commitments were made public

    JF Dehecq made clear commitments with regards to

    maintaining sanofi-aventis activities in the countries

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    One line of command nominated very earlyin the process

    Parity rule for managementnomination and theprinciple of a single line ofcommand were announcedupfront

    This has beenimplemented very rapidlywith a top down approach:

    June: Draft structure offuture ManagementCommittee announcedAug: Executive committeenominations

    Early Sep: Generalmanager nominationEnd Sep: Affiliatemanagement committeenomination

    sanofi-aventis

    Communiqu de presse Paris, le 6 Sept. 2005

    NOMINATIONS DE 100 DIRIGEANTS

    Sanofi-Aventis annonce aujourdhui la nomination

    dune centaine de dirigeants dans plus de 70 pays

    Les Responsables des 2ones Gographiques

    Les Directeurs Rgionaux

    Les Directeurs Gnraux

    Les Responsables des Oprations Commerciales

    Les Responsables Franchises du Marketing

    Global

    Les nouveaux Directeurs Gnraux auront un rle

    majeur dans la construction du Groupe Sanofi-Aventis. Ils nommeront dici la fin du mois de

    Septembre lquipe de direction dans leurs pays

    respectifs, et feront en sorte que les oprations

    soient totalement intgres dici la fin de lanne

    2005.

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    Rapid decisions regarding sites andinfrastructure in view of cost optimization

    Rapid decisions

    regarding information

    systems based on

    economic rationale

    From 5 Corporate

    Headquarters to only

    1 in Paris

    Closure of 70 localheadquarters

    COUNTRY SASY HQ site TOWN

    ADRIATICS AVE/OTHERS As per cases

    ALGERIA Alger OTHERS Alger

    ARGENTINA Buenos Aires AVE #REF!

    AUSTRALIA Sydney, New Zeland OTHERS

    BANGLADESH None AVE Dhaka

    BRASIL Rio AVE #REF!

    BULGARIA Sofia OTHERS Sofia

    CENTRAL AMERICA Guatemala City AVE #REF!

    CHILE Santiago SASY Santiago

    CHINA Shanga SASY Shanga

    COLOMBIA Cali/ Bogota AVE Bogota

    DOM/TOM OTHERS/AVE As per cases

    DOMINICAN REPUBLIC Santo Domingo AVE #REF!

    ECUADOR Guayaquil AVE #REF!

    EGYPT Le Caire AVE Le Caire

    GUATEMALA AVE Guatemala City

    GULF AVE

    HONG KONG Hong Kong TBD Hong Kong

    INDIA Bombay AVE Bombay

    INDONESIA Jakarta AVE Jakarta

    IRAK

    IRAN

    ISRAEL Raanana AVE #REF!

    JAPAN Tokyo AVE Tokyo

    LIBAN Beyrouth AVE Beyrouth

    MALAYSIA Kuala Lumpur OTHERS

    MEXICO Cuautitlan AVE Mexico

    MORROCO Casablanca AVE

    OTHER EASTERN EUROPE (CIS) OTHERS As per cases

    PAKISTAN None AVE Karachi

    PANAMA AVE Guatemala City

    PARAGUAY Paraguay Paraguay

    PERU Lima AVE Lima

    PHILIPPINES Makati SASY MakatiROMANIA Bucarest OTHERS Bucarest

    RUSSIA Moscou OTHERS Moscou

    SAUDI ARABIA Jeddah SASY Jeddah

    SINGAPORE Singapour AVE/SASY Singapour

    SOUTH AFRICA Johannesbourg AVE Johannesbourg

    SOUTH KOREA Seoul AVE Seoul

    SUB SAH AFRICA AVE Dakar

    TAIWAN Taipei TBD Taipei

    THAILAND Bangkok AVE Bangkok

    TUNISIA/LYBIA Tunis AVE Tunis

    UKRAINE Kiev OTHERS Kiev

    URUGUAY Montevideo Montevideo

    VENEZUELA Caracas AVE Caracas

    VIETNAM Saigon Hanoi

    IllustrativestatusreportforITCsiteselection

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    Status: May 2007

    Clearly defined rules of the game

    Conversational styleInformal interaction in parallel of formal reporting / submissions to explaincontext elementsTransversal coordination throughout the integration networkOpen dialogue also beyond hierarchy in view of rapid problem solvingRespect of colleagues and of their opinion (the right to challenge is linked to theobligation to listen)

    Structured and disciplined integrationCompliance with integration process and timelinesRole and responsibilities of all actors in the integration network well definedEfficient reporting, control, validation and decision processes

    Objective driven approachBusiness objectives guide the integration processCombined operations perspective (instead of relating back to the legacy context)

    Clear prioritization and pragmatic solutions

    People focusEncourage active participation of all key actors of the organizationRecognize past merits

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    Solid project preparation with a small coreteam

    Anticipative project preparation (full project preparation finalized

    by end of July 04)

    Internal solutions and expertise (minimal external support)

    Massive mobilization of internal resources in all parts of theorganization while ensuring continuity at operational

    management level

    A very small core team at Operations level:

    non-invasive reporting (only what 3 people could review)Pragmatic approach

    Very direct coordination / support

    Best use of in-house expertise / and knowledge

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    A decentralized project structure withintegration offices at all level

    Decentralized integration officesIntegration offices at Operations,Region and Country levelAn Integration officer from eachlegacy companyPermanent coordination betweenIntegration officers and operational

    management at all level of theorganizationRegular integration officermeetings to exchange experiencesand adapt overall project structure

    Workstreams1

    Strong cross-functional interactionExpert groups on critical subjects

    1) See list of workstreams in the appendix

    OpIO(OperationsIntegration

    Office)

    OpIO(OperationsIntegration

    Office)

    RIO(US, FR, G, J,Europe, ITC,and G-MKT)

    RIO(US, FR, G, J,Europe, ITC,and G-MKT)

    AIO(Affiliates)

    AIO(Affiliates)

    Closeinte

    ractions

    withG

    Prog

    ressreport

    andsubmis

    sion

    Gu

    idelines

    andsupport

    Progress

    report

    andsubm

    ission

    Guidelines

    andsup

    por t

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    Status: May 2007

    Tight planning and an ambitious target

    Tight planning

    June 04: Finalized design of the integration infrastructure(integration teams, milestones) and of the integration guidelines

    August 04: launch of integration teams at all level and in all entitiesof the company

    End of December 04: Dissolution of the integration network andtransfer of all tasks to the relevant functional / operational entities

    A shared and ambitious target:

    January 1st 2005: sales forces fully operational in the field allaround the world

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    Merger sanofi-aventis in Germany

    Main issues of business structure:

    Clarifying of direction of business transfer

    Merge of sales force lines(appr. 1,500 eees) effective January 1st, 2005

    Transfer of support functions from Bad Soden to Berlin (appr. 300 eees) till March 1st, 2005

    Transfer of support functions from Berlin to Frankfurt (appr. 80 eees) till March 1st, 2005

    Transfer of Corporate activities to Paris

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    ISSUES

    Main issues labour law:

    Balance of interest and socialplan

    Collective agreement about new structure of works council

    HR transfer agreement

    before January 1st, 2005

    Company related collective agreement between union and employers association about membershipin employers association Nordostchemie: August 2005

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    Merger sanofi-aventis

    Further issues:

    Integration of payroll

    Transfer of appr. 1,100 eees ex SaSy from former System in SAP-System till January 1st, 2005

    Harmonization of pension benefit schemes

    Becoming effective September 1st, 2005

    ...

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    Main issues Compensation

    :

    Harmonization of compensation systems

    Harmonization of sales force premium systems

    Before January 1st, 2005

    Implementation of a corporate wide IVR-Systems

    (Individual Variable Remuneration)1. Quarter 2005

    Harmonization of employee benefits (Cafeteriasystem, Leasingcars etc.)

    2. Quarter 2005

    O l ti l k t

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    Our values: an essential key to ourcollective and individual success

    Courage

    our collective approach, our commitment to success

    Creativity

    our ability to do things differently

    Respect

    our behavior, our social dimension

    Solidarity

    our readiness to fight alongside our fellow human beings

    wherever and whoever they may be

    Audacity

    our aptitude for exploration, discovery, innovation

    Performancethe key to our future

    P & C f S fi A thi

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    Pros & Cons of Sanofi - Aventhis

    Sales will increase & would support Cardiovascular franchise

    Decrease Sanofis forecast percentage growth

    Will increase Sanofis size

    Operate in Seven therapy area

    Forth largest player

    Help to integration due to similar working culture

    New pharmaceutical Giant

    10000 12000 jobs could go

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    THANK YOU.