Proceedings of the 25th

Annual International Conference of the IEEE

Engineering in Medicine and Biology Society

Volume 25

A New Beginning for Human Health

1

Volume 1 of4>*«%J^^(,

17 - 21 September 2003

Cancun, Mexico

UNIVEKSITATSBl&iK" -

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HANNOVER

TECHNISCHEJWORMATIONSBIBUOTHCK

Conference Chair and Co-Chair

Jorge E. Monz6n

Jose C.

Program Chair and Co-Chair

Joaquin Azpiroz Leehan

lis Coatrieux

Publications Chair

Ron S. Leder

IEEE >AV EMBCasa abierta al tiempo -(o-

CORAL

UB/TIB Hannover 89

121 616 924

Table of Contents

Theme 1. Cardiovascular and Respiratory SystemsJohn Clark, Rice University, Sergio Cerutti, Polytechnic University

Track 1.1: Cardiac ElectrocardiologyRonald Wildcrs, Academic Medical Center, University of Amsterdam

Session 1.1.1: Cardiac Activation: Focus on VentriclesRonald Wilders, Academic Medical Center, University of Amsterdam; Mary Wagner, Emory University

Thursday Sep-18-2003, 10:30 - 12:30 (Coral Kingdom I, Slide)

1. Cardiac Excitation and Propagation: What Can We Learn From 0D-2D Models? 1

Joyner, Ronald W., Emory Umveisity

2. Action Potential Models of Murine Cardiac Ventricular Cells 4Demir, Scmahal S., Univ of Memphis & Univ ofTennessee, Isik Univ

3. Calcium Regulation and Cellular Electrophysiology 7llund, Thomas J.; Rudy, Yoram, Case Western Reserve University

4. The Role of Ca2+ Channel Blockers in the Transition from Ventricular Fibrillation to Ventricular Tachycardia in an

Anatomical Model of the Human Ventricles : a Simulation Study 9Bernus, Olivier G ; Verschelde, Henri; Panfilov, Alexander V., Ghent University

5. Modulation of Triggered Activity by Uncoupling in the Ischemic Border. A Model Study with Phase lb-LikeConditions 13

Pollard, Andrew E., University of Alabama at Birmingham

6. Electrical Activity and Reentry in Acute Regional Ischemia: Insights from Simulations 17

Ferrero, Jr., Jose M, Trcnor, Bcatnz; Saiz, Javier; Montilla, Fulgencio, Hernandez, Vicente, Universidad Politecnica de Valencia

7. A Mathematical Model of Ca2+-Releasc and Ca2+ Balance During Systole in Rat Ventricular Myocytes 21

Sun, Liang, Clark, John W , Fan, Jing-Song; Palade, Philip T, Rice University, MS-366

Session 1.1.2: Cardiac Activation: From Sinus Node to Ventricles

Ronald Wilders, Academic Medical Center, University of Amsterdam; Ronald Joyner, Emory University

Thursday Sep-18-2003, 13:30 - 15:30 (Coral Kingdom I, Slide)

1. A Gradient Model or the Rabbit Sinoatrial Node 24

C'lohcrty, S 1., Dokos, S, l.ovell, Nil, University of New South Wales

2. Rabbit Sino-Atrial Node Modeling: from Single Cell to Tissue Structure 28

Ciainy. Alan, Hunter, Peter J, Noble, Denis, Uoyelt, Mark R.; Kohl, Peter, University of Oxford

3. Bradycardia in LQT3 Patients: Insights from 0D Models 32

Wilders, Ronald, Vcldkamp, Maricke W.; Uaortscheer, Amonius, Zcgcrs, Jan G.; Bczzina, Connie R.; Wilde, Arthur A M., Academic

Medical Center, University of Amsterdam

4. Effect of Calcium-Activated Chloride Current Blockade on Altcrnans of Atrial Action Potentials. Simulation Study 36

(iomis-Tena, Julio; Saiz, Javier, Ferrero, Jr., Jose M , D Ing Fleclronica - LTS1I - UPV

5. Induced Triggered Activity in Isolated Rat Cardiac Cells by Incorporation of a Stretch Activated Conductance 40

Wagner, Mary U , Wang, Yanggan; Kumar, Rajiv; Joyner. Ronald W , Kmory Umveisity

6. Gender Differences in Cardiac Electrophysiology 44

Veikerk. Aric (), Wildeis, Ronald, "Ian, llanno 1, Academic Medical C'cniei, University of Amsterdam

7. Modeling ofthc Long-QT Syndrome Type 1 and 2 48

Conialh, Chuni.il !•, Wildeis, Ronald, Jongsma, 1 labo J ; Optliof. 'Iobias. Academic Medical Center, University of Amsterdam

Contents - 1

Session 1.1.3: Cardiac Electric Fields: Natural and ImposedRonald Wilders, Academic Medical Center, University of Amsterdam; Andrew Pollard, University of Alabama at Birmingham

Friday Sep-19-2003, 8:00 - 10:00 (Coral Kingdom I, Slide)

1. Normal and Fractionated Cardiac Near Fields and Their Relation to Microstructure - an Experimental Approach 51

Hofer, E ; Sanchez-Quintana, D.; Plank, G.; Tisohler, M., Karl-Franzens-Universitat Graz

2. Automated Modeling of Cardiac Electrical Activity 55

Syed, Zainab F.; Vigmond, Edward; Leon, L. Joshua, University of Calgary

3. Do Ventricular Repolarization Interval Ratios Depend on Heart Rate and Should They Be Rate-Corrected? 59

Alvarado-Serrano, Carlos, Ramos-Castro Juan; Pallas-Areny Ramon, CINVESTAV-IPN

4.3D Finite Element Complex Domain Numerical Models of Electric Fields in Blood and Myocardium 62

Wei, Chia-Ling; Valvano, Jonathan W.; Feldman, Marc D.; Nahrcndorf, Matthias; Pearce, John A.,The University of'I'exas at Austin

5. A Torso Phantom for the Assessment of Active and Passive Vortex Currents 66

Haueisen, Jens; Liehr, Mario; Dutz, Silvio; Leder, Uwe; Nenonen, Jukka; Bellemann, Matthias E., Biomagnetic Center, Friedrich-

Schiller University

6. ECG Simulations with Realistic Human Membrane, Heart, and Torso Models 70Potse, Mark; Dube\ Bruno; Gulrajani, Ramesh M., University de Montreal

7. Derived Electrocardiograms on the Posterior Leads from the 12-Lead System: Method and Evaluation 74

Wei, Darning , University of Aizu

Session 1.1.4: Cardiac Electrophysiology: PostersRonald Wilders, Academic Medical Center, University of Amsterdam

Thursday Sep-18-2003, 13:30 -15:30 (Coral Gallery, Poster)

1. An Automated Measure of P-Wave Duration from Surface ECG Maps 78Damiani, S.; Barbara V.; Congi, M.; Poli, S.; Calcagnini, G.; Censi, F.; Bartolini, P., Lab, Ing. Biomediea Istituto Superiore di Sanita

2. A New Phase Space Analysis Algorithm for Cardiac Arrhythmia Detection 82Tuck, Wong Mun; Srinivasan, N.; Krishnan, S. M., Nanyang Technological University

3. A Spatial Study of the ST Segment 86Gonzalez, Rene !.; Canizares, Maite; Rodriguez, Gemma; Meissimilly, Gay A,, Central Institute for Digital Research

4. Implementation and Verification of Sinoatrial Node Math Model 90Sierra Bueno, Daniel A.; Correa Cely, Rodrigo; Rueda Ochoa, Osear L, Universidad Industrial de Saniander

Track 1.2: Cardiac MechanicsJohn Li, Rutgers University

Session 1.2.1: Cardiac Mechanics

John Li, Rutgers University; Peter Kerkhof, Vu Medical Center

Thursday Sep-18-2003, 10:30 -12:30 (Coral Kingdom II, Slide)

1. Effective End-Systolic Von Left Ventricle and Its Contribution to Cardiac Function Indexes 94Kerkhof, Peter L., VU Medical

2. High Resolution Work Lot, eans for Evaluating Regional 97Chiang, F. P.; Azeloglu, E. U.; Saltman, A. E.; Krukcnkamp, 1. B.; Gaudette, G. R.

,State University ofNew York at Stony Brook

3. Myocardial Stunning Analyzed by a Single Muscle Fiber Model 100Li, John K. J.; Drzewiecki, Gary; Barton, Tracy; Khaw, Kenneth; Kedcm, Joseph, Rutgers University

4. Estimation ofActive Myocardial Force Development: a Feasability Study in a Potentially Clinical Setting 103Claus, Piet; McLaughlin, Myles; D'hooge, Jan; Sutherland, George R.; Bijnens, Bart, Cardiac Imaging Research

5. Frequency Based Analysis of Diastolic Function 107Wu.Yu; Bowman, Andrew; Chung, Charles; Karamanoglu, Mustafa; Kovacs, Sandor J., Washington University

6. Modelling the Error in Ultrasound Tissue Dopplcr Measurements Due to Incorrect Transducer Placement 111Storaa, Camilla; Palmberg, Nanna; Brodin, Urs-Ake; F.lmqvist, Hakan, Royal Institute of Technology

7. Alterations of Coronary Perfusion Pressure and Cardiac Contraction during Lipopolysaccharidc Challenge 115Tu, Jic

, Zhejiang University School of Medicine

8. Dendranthema Morifolium Attenuated the Reduction of Contraction of Isolated Heart and Cardiomyocytcs Inducedby Ischcmia/Reperfusion and Anoxia/Rcoxygcnation 119Jiang, Huidi , Zhejiang University

Contents - 2

9. Segmentation and Analysis of 3D Cardiac Motion from Tagged MRI 122Metaxas, Dimitris N

, Axel, Leon, Hu, Zhenhua, Montillo, Albert, Rutgers University

Track 1.3: Pacing, Defibrillation, and AblationDorin Panescu, Boston Scientific

Session 1.3.1: Cardiac Ablation

Dorin Panescu, Boston Scientific, Dieter Haemmench, University of Wisconsin-Madison

Friday Sep-19-2003, 10:30 - 12:30 (Coral Kingdom I, Slide)

1. Evaluation of Ablation Patterns by Means of a Computer Model of Human Atria 126Dang, Lam, Virag, Nathalie, Ihara, Zenichi, Jacquemet, Vincent, Blanc, Olivier, Vesm, Jean-Marc, Kappenberger, Lukas, SwissFederal Institute of Technology, EPFL

2. A Novel Linear Ultrasound Technology for the Ablation of Cardiac Tissue 130Podany, Vaclav, Kwok, Jonathan, Pendekanti, Rajesh, Ethicon

3. Thermal Dose versus Isotherm as Lesion Boundary Estimator for Cardiac and Hepatic Radio-Frequency Ablation 134Haemmench, Dieter, University of Wisconsin-Madison

4. Prototype of a Fluoroscopic Navigation System to Guide the Catheter Ablation of Cardiac Arrhythmias 138Sierra, Gilberto, LcBlanc, A Robert, Lionard, Melame, Nadeau, Reginald, Savard, Pierre, Ecole Polytechmque

5. Offset Bipolar Electrode Technology for Minimizing Collateral Thermal Damage 142Washington, Ebonia, Zaddem, Vincenza, Gordon, Dan, Pendekanti, Rajesh, ETHICON, a Johnson & Johnson Company

6. Voltage-Sensitive Optical Mapping for Atrial Fibrillation Ablation Treatment 145Furman, Michael D, Simonotto, Jennifer D, Beaver, Thomas M , Spano, Mark L, Ditto, William L, Liu, Gang, Kavanagh, [CatherineM

, University of Floi Ida

7. Intra-Operative Epicardial Lesions in the Atria Using a Multielectrode RfSystem 148Panescu, Dorin, Mangrum, Michael, Everett, Thomas H

, Li, Hiu, Haines, David E, Boston Scientific

Session 1.3.2: Defibrillation Therapy I: Simulation and ModelingDorm Panescu, Boston Scientific, Wayne Mcdaniel, University of Missouri

Friday Sep-19-2003, 13:30 - 15:30 (Coral Kingdom I, Slide)

1. Effect of Acute Global Ischemia on Cardiac Vulnerability to Electrical Shocks 151Rodriguez, Blanca, Eason, James C , Tice, Brock, Ferrero, Jr, Jose M

, Trayanova, Natalia, Tulane University

2. Energy Adjustment Method Based on Transthoracic Impedance for a Biphasic Defibrillator 155Portela, Alejandro E , Folgueras, Jose, Colorado, Osmam ,

Central Institute for Digital Research

3. A Simulation Study of Ventricular Rate Smoothing During Atrial Fibrillation 159Lian, Jie, Mussig, Dirk, Lang, Volker, Micro Systems Engineering, Inc

4. Paroxysmal Atrial Fibrillation Prediction Using Isolated Premature Atrial Events and Paroxysmal Atrial

Tachycardia 163fhong, I ran, McNames, James, Aboy, Mateo, Goldstein, Biahm, Oregon Health & Science University

5. Shock Energy for Successful Defibrillation of Atrial Tissue during Vagal Stimulation 167Plank, Gemot, Vigmond, Edwaid J

, Leon, Louis J, University ofGraz

6. Restitution of Action Potential Duration during Sequential Activation: a Simulation Study 171Wti, Run/e, Abhijit, Patwardhan, University of Kentucky

Session 1.3.3: Defibrillation Therapy II: In Vivo Studies

Wayne Mcdaniel, University of Missouri; Dorin Panescu, Boston Scientific

Saturday Sep-20-2003, 8:00 - 10:00 (Coral Kingdom I, Slide)

1. A System for In-Vivo Cardiac Defibrillation Current Density Imaging in a Pig 175

DeMonte, Tim P, Yoon, Richaid S

, Jorgenson, Dawn B, Joy, Michael L G , University of Toronto

2. Rapid Current Switching with an Endovascular Electrode Configuration Significantly Decreases ImplantableDefibrillator Thresholds 179

Dosdall, Deiek J, Sweeney, J<tmes D , Brandon, Tedd A , Arizona State University

3. Comparison of the Efficacy of Two Biphasic Waveiorm Defibrillators m a Model of Simulated Higher ImpedancePatients 183

McDamcl, Wayne C , Gancll, Michael, Burke, Martin C, Arzbaecher, R, University of Missoun

Contents - 3

4. Comparative Effects of Bipolar Single Site and Bipolar Linear Triple Site Pacing on Atrial Activation - Studies in

Canine Models 186

Ryu, Kyungmoo, Waldo, Albert L,Khrestian, Celcen M , Goldstein, Robert N

, Sahadevan, Jayakumar, Doiostkar, Parvin C,

C asc

Western Reserve University

5. Preliminary Results on the Performance of a Biphasic Cuban Defibrillator in Swine 190

Folgueras-Mendez, Jose, Portela, Alejandio E, Milane's, Alejandro A , Colorado, Osmam, Guevara, I uis I

, Tomes, I ranusco J,

Druyet, Dahlys, Dominguez, Eberto, Central Institute for Digital Research

6. A Comparison between Transthoracic Impedance and Body Mass Index as Indicators of the Energy for

Cardioversion 193

Folgueras-Mendez, Jose, Portela, Alejandro E,Colorado

, Osmam, Central Institute toi Digital Research

7. Nonlinear Analysis of Failed Ventricular Defibrillation 196

Simonotto, Jennifer D, Furman, Michael D

, Ditto, William L, Spano, Maik L, Lui.Gang, Kavanagh, Kathcunc M, University ol

Florida

Track 1.4: Heart Rate Variability and Control of Blood Pressure

Sergio Cerutti, Polytechnic University; Hartmut Dickhaus, University ofHeidelberg

Session 1.4.1: Heart Rate Variability: Methods of AnalysisSergio Cerutti, Polytechnic University; Hartmut Dickhaus, University of Heidelberg

Saturday Sep-20-2003, 10:30 - 12:30 (Coral Kingdom I, Slide)

1. Discrimination Power of Long-Term Heart Rate Variability Measures 200

Asyah, Musa H, King Faisal Specialist Hospital & Research Center

2. Instantaneous Monitoring of Heart Rate 204

Barbien, Riccardo, MGH-Harvard Medical School

3. Frequency Domain Analysis of Heart Rate Variability in Sleep Disordered Breathing 208

Vijendra, Sridhar, Behbeham, Khosrow, Burk, John R, Lucas, Edgar A ,Dao, Dzu H

, Nazeran, Homer, University of Texas at

Arlington

4. Reliability and Accuracy of Heart Rate Variability Metrics Versus ECG Segment Duration 212

McNames, James, Thong, Tran, Goldstein, Brahm, OHSU

5. Robust Extraction of Autonomous Nervous Profile Using a Non-Invasive Method 216

Vetter, Rolf, Virag, Nathalie, Renevey, Philippe, Krauss, Jens, CSEM

6. Time-Frequency Assessment of Heart Rate Variability under Valsalva and Mueller Maneuvers 220

Mendez, Martin O, Gaitan, Mercedes J.; Carrasco, Salvador, Universidad AutOnoma Metropolltana-Izlapalapa

7. Time-Frequency Mapping of the Magnitude Squared-Coherence for Intra-QRS Potentials Detection 224

Barbosa, Paulo R B., Bernardino, Jr, Luiz C , Barbosa-Filho, Jose; Cordovil, Ivan; Nadal, Jurandir, COPPE/ UFRJ

8. Heart Rate Variability in Rats with Aldosterone-Induced Chronic Heart Failure 228

Raphisak, Pisut; Curry, Amy de Jongh; Malkin, Robert A ; Schuckers, Stephanie C, Clarkson University

Session 1.4.2: Heart Rate Variability: Posters

Sergio Cerutti, Polytechnic University; Hartmut Dickhaus, University of Heidelberg

Saturday Sep-20-2003, 16:00 - 18:00 (Coral Gallery, Poster)

1. Comparison of Indexes of Respiratory Sinus Arrhythmia 232

Mantaras, Carla; Carrasco, Salvador; Gaitan, Mercedes J, Gonzalez, Ram6n, Universidad Autonoma Mctropohlana - Iztapalapa

2. Toward Quantitative Monitoring of Human Cardiotocography during Labor 236Cao, Hanqing, Lake, Douglas E., Chisholm, Christian A

, Ferguson, James E, Griffin, M Pamela, Mooiman, J Randall, University of

Virginia

3. Evaluation Method for the Metabolic and the Autonomic Nervous Systems Link Response Using Indirect

Calorimetry and Heart Rate Variability 240

Cadena, Miguel M ; Infante, Oscar V ; Ramirez, Evelin, Lerma, Claudia, Lscalanlc, Boris, Sanchez, Gustavo, UNIVLRSIDADAUTONOMA METROPOLITANA

4. Reconstruction of Underlying Heart Rate from Integrated Pulse Frequency Modulated Heart Pulses with l/fFluctuations 244Kishida, En, Kato, Yoichi, Mizuta, llirohisa, Yana, Ka/uo, Kyoso, Masaki, Ishijima, Masayuki, Ishihara, Yoko, llo, Isuyoshi, lamuu,

Kumiko, Hosei University

5. Detection of Inspiratory Efforts by Complex Demodulation of Pulse Transit Time in Children 248

Calcagnini.G.Censi, F, Pagan i, J, Vannucci, F

, Villa, M P, Ronchctn, R, Baitohm, P

,Baibaio, V

,Istuuto Supenorc di Sumta

Contents - 4

Session 1.4.3: Control of Arterial Blood Pressure

Hartmut Dickhaus, University of Heidelberg, Sergio Cerutti, Polytechnic University

Saturday Sep-20-2003, 13:30 - 15:30 (Coral Kingdom I, Slide)

1. Linear and Nonlinear Interaction Analyses of Heart Rate and Blood Pressure in Pregnancy Induced Hypertension 252Voss, Andreas, Baumert, Mathias, Baier, Vico, Stcpan, Holger, Walther, Thomas, Faber, Renaldo, University of Applied Sciences Jena

2. Characterization of Baroreflex Response under Head-Up Tilting 256Nakao, Mitsuyuki, Tohoku University

3. Semi-automatic System Developed to Quantify Arterial Baroreflex Sensitivity 260Macedo, Adnana R; Rocha, Nazaerth N ; OliveiraLeonardo, P. J

, Nobrcga, Antonio C. L ; Souza, Marcio N,Federal University of

Rio de Janeiro

4. Use of Skin Resistance to Detect Steady-State Rest Condition in a Subject During Cardiovascular Measurements 264

Piccini, Luca; Castighoni, Paolo, Usee', Laura, Zanctti, Luisa; Andreoni, Giuseppe; Di Ricnzo, Marco, Fondazionc Don C Gnocchi,Politecmco di Milano

Track 1.5: Vascular and Valve Mechanics, and HemodynamicsCraig Hartley, Baylor College of Medicine; Christopher Quick, Texas A&M University

Session 1.5.1: Hemodynamic AnalysisChristopher Quick, Texas A&M University; Craig Hartley, Baylor College ofMedicine

Thursday Sep-18-2003, 13:30 -15:30 (Coral Kingdom II, Slide)

1. Estimating Arterial Properties from Doppler Signals in Mice 268

Hartley, Craig J, Reddy, Anilkumar K ; Michael, Lloyd H ; Pocius, Jennifer S ; Pham, Thuy T, Entman, Mark L, Taffet, George E.

, Baylor College of Medicine

2. Noninvasive Detection of Atherosclerosis by Arterio-Oscillo-Gram 272Pouladian, Majid; Golpayegani, Mohammad R H

,Sceince and Research Branch ofAzad University

3. Indices of Aoric Stiffness in Mice 276

Reddy, Anilkumar K., Li, Yi-Heng, Pham, ThuyT., Taffet, George E, Michael, Lloyd H

, Entman, Mark L; Hartley, Craig J., BaylorCollege of Medicine

4. Robust Algorithm to Extract Systoles and Diastoles from Continuous Blood Pressure Signal 279

Perfetto, Juan Carlos, Ruiz, Aurora; Mazzeo, Jorge; D'Attellis, Carlos, Buenos Aires University

6. Hemolab: a Custom Built Diagnostic Tool for Non-Invasive, Synchronized Recording and Real-Time Monitoring of a

Doppler Spectrogram, an Electrocardiogram and Arterial Tonometry 285

Matthys, Koen S, Segers, P ; Vanhercke, D.; Carher, S G ; Verdonck, P. R

,Ghent University

Session 1.5.2: Vascular Mechanics

Craig Hartley, Baylor College of Medicine, Christopher Quick, Texas A&M University

Thursday Sep-18-2003, 16:00 - 18:00 (Coral Kingdom II, Slide)

1. Endovascular Embolization of Aneurysms with ALGEL®: an in Vitro Study of Delivery Techniques and ResultingGel Stability 289

Becker, Timothy A , Kipke, Daryl R.; Brakora, Kaylan M , University of Michigan

2. Chronic Assessment of ALGEL® for Endovascular Embolization of an Arteriovenous Malformation Model in Swine 293

Becker, Timothy A.; Kipke, Daryl R.; Preul, Mark C, Bichard, William D.; McDougall, Cameron G., University of Michigan

3. Enhanced Venous Compliance Sensibility at Physiological Ranges of Pressure: Experimental Validation of a

Biphasic Model 297

Molas, Maria C; Armentano, Ricardo; Bia, Daniel, Z6calo, Yanina; Craicm, Damian; Risk, Marcelo, Favaloro Umveisity

4. Isobaric Elastic Mismatch Among Native Arteries And Conduits Used In Systemic Vascular By-Pass 301

Molas, Maria C, Armentano, Ricardo, Bia, Daniel, Z6calo, Yanina, Lavina, Guillermo, Craiem, Damian, Voliovici, Eduaido, Bonilla,

Fernando, Cabrera-Fischei, Edmundo I., Favaloro University

5. Vasorelaxant Effect of Total Flavones from Dendranthema Morifolium on Rat Thoracic Aorta 305

Jin, I longfeng, Zhejiang University School of Medicine

6. Novel Temperature Based Technique for Measurement of Endothelial Dysfunction 308

Kharalkai, Nachiket, Valvano, Jonathan, Naghavi, Morteza; Wei, Chia-Ling, University of Texas at Austin

7.1-D Blood Vessel Modeling: Vessel Area and Flow Rate Control 312

Pourlahcn, Navid ,Duke University

Contents - 5

Session 1.5.3: Myocardial and Vascular Mechanics: Posters

Craig Hartley, Baylor College of Medicine; Christopher Quick, Texas A&M University

Friday Sep-19-2003, 10:30 - 12:30 (Coral Gallery, Poster)

1. Time-Frequency Distribution Applied to Blood Flow Velocity Profiles 316

Rubio Acosta, Ernesto, Medina, Lucia, Rodriguez, Alfredo O, IIMAS, UNAM

2. The Application Of Polarization Microscopy To The Development Of A Non-Staining Technique For Measuring The

Divergence Angle Of Myocardial Collagen Cleavage Planes 320

Baba, Justin S., Texas A&M University

3. Applying the Time-Varying Elastance Concept to Determine the Optimum Coordination of Lymphangion

Contraction in a Lymphatic Vessel 323

Vcnugopal, A M ; Stewart, R H ; Rajagopalan, S, Zawieja, D C, Lame, G A

, Quick, C M,Texas A&M University

4. Evaluating the Time-varying Elastance Concept for Lymphangions 327

Rajagopalan, S ; Stewart, R. H., Venugopal, A. M.; Lame, G A , Zawieja, D. C; Quick, C M,Texas A&M University

Track 1.6: Current Issues in Sleep ApneaMichael Khoo, University of Southern California

Session 1.6.1: Sleep Apnea I: Analysis of Cardiorespiratory VariabilityMichael Khoo, University of Southern California; Sergio Cerutti, Polytechnic University

Friday Sep-19-2003, 8:00 - 10:00 (Coral Kingdom II, Slide)

1. Study of Cardiovascular and Respiratory Signals During Sleep 331

Bianchi, Anna M.; Cerutti, Sergio , Polytechnic University

2. Rhythm or Morphology? Which Information in the ECG Is More Useful with Respect to Detection of Sleep Apnea? 334

Dickhaus, Hartmut, University of Heidelberg

3. Computer-Based Analysis of Heart Rate Variability Signal for Detection of Sleep Disordered Breathing in Children 338

Nazeran, Homayoun; Pamula, Yvonne, Gradziel, Aldona; Ung, Kavin; Vijendra, Sridhar; Behbehani, Khosrow, University of Texas at

El Paso

4. Detecting Pediatric Obstructive Sleep Apnea Using Ecg 342

Pu, Yachuan, Patterson, Robert; Bomcmann, Michel, University of Minnesota

5. Nonlinear Assessment of Autonomic Function in Obstructive Sleep Apnea during Long-Term Cpap Therapy 346

Jo, Javier A.; Khoo, Michael C. K.; Blasi, Anna; Baydur, Ahmet; Juarez, Ricardo,Cedars-Sinai Medical Center

6. Time-Varying Analysis of Autonomic Control during Arousal from Sleep in Obstructive Sleep Apnea Syndrome 350

Blasi, Anna; Jo, Javier A.; Valladares Edwin; Juarez, Ricardo; Baydur, Ahmet; Khoo, Michael C. K., University of Southern California

7. Heat Rate Variability during Sleep and the Development of Ptsd Following Traumatic Injury 354

Knorr, Bethany R.; Akay, Metin; Mellman, Thomas A., Dartmouth College, Thayer School

Session 1.6.2: Sleep Apnea II: Recent Advances in Diagnostic and Therapeutic Modalities

Thomas Penzel, Hospital of Philipps University; Michael Khoo, University of Southern California

Friday Sep-19-2003, 10:30 - 12:30 (Coral Kingdom II, Slide)

1. Problems in Automatic Sleep Scoring Applied to Sleep Apnea 358

Penzel, Thomas; Kesper, Karl; Gross, Volker; Becker, Heinrich F.; Vogelmeier, Claus, Hospital of Philipps University

2. The Assessment of REM Sleep Homestat ic Regulation Using An Automated Laboratory for Sleep Studies 362

Vivaldi, Ennio A., Universidad de Chile

Automatic Snoring Signal Analysis in Sleep Studies 366

Jane, Raimon; Fiz, Jos6 A, Sola-Soler, Jordi, Blanch, Silvia, Arils, Pere; Morera, Jos<£, Umversitat Polit6cmca de Catalunya

A Computational Model of Upper Airway Collapslbllity 370

Huang, Yaqi, Malhotra, Atul, White, David P, Bngham and Women I lospilal,Harvard Medical School

.In-Vitro Study of Pharyngeal Pressure Losses at the Origin of Obstructive Sleep Apnea 371Van Ilirtum, Annemic, Chouly, Franz, Teul6, Alexis; Payan, Yohan; Pelorson, Xavier, ICP

. Development of Asynchronous, Intralingual Electrical Stimulation to Treat Obstructive Sleep Apnea 375Tran, Winston II

, Locb, Gerald E ; Richmond, Francis J R., Duponl, Anne C, Mahuttc, Kecs C ; Sassoon, Catherine S II

, Dickel,Michael J

, University of Southern California

Contents - 6

Track 1.7: Cardiopulmonary Engineering and Critical Care MedicineMichael Khoo, University of Southern California; Akhil Bidani, Ut Health Science Center at Houston

Session 1.7.1: Cardiopulmonary and Cerebrovascular ModelingMichael Khoo, University of Southern California, John Clark, Rice University

Friday Sep-19-2003, 13:30 -15:30 (Coral Kingdom II, Slide)

1. Modeling the Respiratory Depressant Effect of Opioids: Application to Fentanyl 379

Magosso, Ehsa, Ursino, Mauro; van Oostrom, Hans, University of Bologna

2. Pressure Transfer Functions to Study Ventricular-Arterial Interaction in Systemic and Pulmonary Circulation 383

Craiem, Damian 0, Armentano, Ricardo, Gngnola, Juan C; Bia, Daniel; Molas, Maria C

, Gmts, Fernando, Universidad Favaloro

3. A Multi-Element Nonlinear Model of Human Circulatory-Respiratory System and Its Application in High-G Study 387

Lu, Hongbing, Bai.Jing, Zhang, Li-Fan, Wang, Shu-Yi, Fourth Military Medical University

4. Acute Cardiovascular Response to High Altitude in Healthy and Anemic Subjects: a Mathematical Model 391

Magosso, Ehsa, Ursino, Mauro, University ofBologna

5. Cerebral Autoregulation and Gas Exchange Studied Using A Human Cardiopulmonary Model 395

Lu, Kun; Clark, J W., Ghorbel, F Ii, Robertson, C. S., Ware, D L; Zwischenberger, J B., Bidani, A., Rice University

6. Nonlinear Analysis of Dynamic Cerebral Autoregulation in Humans under Orthostatic Stress 398

Mitsis, Georgios D.; Mahahngam, Aarthi, Zhang, Rong, Levine, Benjamin D.; Marmarehs, Vasihs Z., University of Southern

California

7. Modeling Intracranial Fluid Flows and Volumes During Traumatic Brain Injury to Better Understand Pressure

Dynamics 402

Wakeland, Wayne; McNames, James; Aboy, Mateo.; Hollemon, Desiree; Goldstein, Brahm, OHSU

Session 1.7.2: Bioengineering Aspects of Mechanical Ventilation

Rob Chatburn, University Hospitals of Cleveland; Steven Conrad, Louisiana State University Health Sciences Center

Saturday Sep-20-2003, 8:00 - 10:00 (Coral Kingdom II, Slide)

1. Engineering Principles Applied to Mechanical Ventilation 406

Chatburn, Rob, University Hospitals ofCleveland

2. Expiratory Flow Limitation in Mechanically Ventilated Patients: a Simulation Study 411

Bnghenti, Chiara ;Gnudi, Gianni, Cevenim, Gabriele, Barbini, Paolo, University of Bologna

3. Reliable Procedure to Switch from Volume Controlled to Pressure Controlled Ventilation Assuring Tidal Volume

during Anesthesia 415

Tamburrelh, Vincenzopio, Silvestn, Sergio, Sciuto, Salvatore A., University Campus Bio-Medico

4. Closed-Loop Control of a Continuous Positive Airway Pressure Device 419

Favre, Andre S., Jandre, Fredenco C, Giannella-Ncto, Antonio, Federal University ofRio de Janeiro

Session 1.7.3: Cardiopulmonary Critical Care EngineeringSteven Conrad, Louisiana State University Health Sciences Center; Akhil Bidani, Ut Health Science Center at Houston

Saturday Sep-20-2003, 10:30 - 12:30 (Coral Kingdom II, Slide)

1. Finite Element Mathematical Model of Fluid and Solute Transport in Hemofiltration Membranes 423

Conrad, Steven A. and Akhil Bidani, Louisiana State University Health Sciences Center

2. Development of a Universal Second Generation Pneumatic Ventricular Assist Device and Drive Unit 427

Sacristan, Emiho; Corona, Farah; Suarcz, Bibiana; Rodriguez, Georgina; Duefias, Benjamin; Gorzelewski, Alicia; Calder6n,

Moisis, Universidad Autonoma Metropolitana

3. Using MicroBubbles to Oxygenate Blood: Possible? 431

Schubert, Roy W ; Conrad, Steven A ; Kim, Sung Sam, Louisiana State University Health Sciences Center

4. Assessing Pulmonary Congestion in Left Sided Heart Failure Using Pulmonary Gas Exchange Parameters 435

Rces, Stephen E ; Malczynski, Jerzy; Korup, Eva, Kjsrgaard, Sorcn, Thorgaard, Per, Andrcassen, Stcen, Toft, Egon, Aalborg

University

Contents - 7

Session 1.7.4: Cardiopulmonary Systems: Posters

Steven Conrad, Louisiana State University Health Sciences Center

Saturday Sep-20-2003, 16:00 -18:00 (Coral Gallery, Poster)

1. Identifying Physiologically Significant Pumping States in Implantable Rotary Blood Pumps Using Non-Invasive

System Observers 439

Lovell, Nigel H , Ayre, Peter J, University of New South Wales

2. Electromyogram Recording of the Diaphragm: Modeling, Simulation, and Experimental Comparison 443

Awada, Ah, Sawan, Mohamad, Bellemare, rrancois, Ecole Polytcchmque de Montreal

3. Effect of Pressure Support Ventilation on the Respiratory Pattern Variability 447

Giraldo, Beatnz F, Chaparro, Javier, Benito, Salvador, Caminal, Peie, technical University ol Catalonia

4. A Physical Model of the Human Lung and Its Application to Mechanic Ventilation Tests 451

Vilcahuaman, Luis, Castillon, Claudio ,Pontificia Universidad Catolica del Peru

5. A System for Automatic Adjustment of the Inspired Oxygen in Mechanically Ventilated Premature Infants 454

Claure, Nelson, Ozdamar, Ozcan, Bancalan, Eduardo, University of Miami

6. Multimedia Database "marburg Respiratory Sounds (mars)" 456

Gross, Volker, University of Marburg

7. An Overview of Heart-Noise Reduction of Lung Sound Using Wavelet Transform Based Filter 458

Hossain, Inna, Moussavi, Zahra, University ofManitoba

8. Nonlinear Control of Microvascular Blood Flow Against Tissue Po2 462

Shibata, Masahiro, Ichioka, Shigeru, Ando, Joji, Kamiya, Akira, Togawa, Tatsuo, University of Tokyo Medical School

9. Physiologic Analysis of Breathing Signals of Cerebral Palsy Characterization 464

Rojas, Rodngo, Gonzalez, Carlos H,Bravo Ricardo

,Universidad Sim6n Bolivar

11. The Phenomenon of Breathing Pattern of Weaning for Success and Failure Groups 467

Hsueh, Meng-Lun ,Institute ofElectrical National Taiwan University

Theme 2. Imaging and Image ProcessingZhi-Pei Liang, University of Illinois at Urbana-Champaign, Yongrrun Kim, University of Washington

Track 2.1: Magnetic Resonance ImagingSteven Wright, Texas A&M University

Session 2.1.1: Magnetic Resonance Imaging I

Zhi-Pei Liang, University ofIllinois at Urbana-Champatgn

Friday Sep-19-2003, 13:30 -15:30 (Coral Garden II, Slide)

1. In Vivo Rabbit Gastrointestinal Wall Imaging Using Endoluminal Coil 470

Beuf, Olivier, Pilleul, Frank, Armencan, Mircea, Armenean, Cnstina, Perrin, Emmanuel, Samt-Jalmes, llervi, Laboratoire de RMN,

Univ Claude Bernard LYON 1

2. Dual Frequency Coil and MRIS Method for the Characterization of Ischemic Injury in the Intestinal Wall 474

Sacristan, Emilio, Baheza, Richard A, Rodriguez, Alfredo O

,Does, Mark, Damon, Bruce, Gore, John

,Universidad Autonoma

Metropolitana

3. An Improved MRI Method for Dynamic Contrast-Enhanced Imaging of Tumors 478

Ji, Jim X, Ma, Jingfei, Aref, Michael, Wiener, Erik, Liang, Zhi-Pei, Texas A&M Umvensty

4. Reliable In vivo Lactate and Lipid Estimation in Glioma Patients 482

Li, Xiaojuan , UC San Francisco/UC Berkeley

5. Evaluation of Noise Effects in Spiral MRI Image Reconstruction Using the Perceptual Difference Model (pdm) 486

Huo, Donglai, Wilson, David L , Salem, Kyle A , Monguchi, Hisamoto,, Case Western Reserve University

S. Identifying Micro-Anatomical Compartments of Mammalian Optic Nerve Based on Nmr T2-Rclaxation Analysis 490

Bonilla, Isidro, Wachowicz, Keith, Snyder, Richard E , University of Alberta

7. Study of Current Density Distribution for a Non-Invasive Breast Cancer Detection Device 494

Yoon, Richard, DeMonte, Tim, Organ, Leslie, Joy, Michael, University oCIoionto

Contents - 8

Session 2.1.2: Magnetic Resonance Imaging II

Joaquin Azpiroz-Leehan, Universidad Autonoma Mctropolitana-Iztapalapa

Friday Sep-19-2003, 16:00 - 18:00 (Coral Gallery, Poster)

1. Folded Crossed-Ellipse Coil for Hand Magnetic Resonance Imaging 497Hernandez, R ; Rodriguez, A ; Salgado, P., Barrios, F.A

,Universidad Autonoma Metropolitan -Izlapalapa

2. Rf Induced Temperature Elevation Near Metallic Wires in Clinical Magnetic Resonance Imaging 501Armenean, Cristina, Perrin, Emmanuel, Armenean, Mircea, Beuf, Olivier; Pilleul, Frank; Samt-Jalmes, Herve, Laboraioirc de RMN,Univ Claude Bernard LYON 1

3. Evaluation of Chemical Shift Imaging Using a Two-Dimensional Presscsi Sequence: Work in Progress 505Wu, Ren H

, Mikuhs, David J.; Ducreux, Denis; Crawley, Adrian, Lin, Rui, Rao, Hai B ; Kong, Kang M , l.ang, Zhi J, terBrugge,Karol, Shantou University Medical College

4. PETal Resonator Band Coil 509

Hidalgo, Silvia, Rodriguez Alfredo 0 ; Rojas, Rafael; Barrios, Fernando A,Universidad Autonoma Metropohtana -lztapalapa

5. Automated Quantitation of Proton Magnetic Resonance Spectroscopic Imaging 513Rao, Sajja B , He, Renjie, Mehta Meghana, Narayana, Ponnada A

,Univ ofTexas Medical School at Houston

Track 2.2: Image Display and VisualizationChristian Roux, Enst Bretagne - Inserm

Session 2.2.1: Image Display and Visualization I

Thursday Sep-18-2003, 13:30 -15:30 (Grand Coral 2, Slide)

1. Projecting Cardiac-Current Images Onto a 3-D Standard Heart Model 517Ogata, Kumomi, Kandon, Akihiko, Miyashita, Tsuyoshi; Tsukada, Keiji, Yamada, Satsuki; Shimizu, Wataru, Nakatani, Satoshi,Miyatake, Kunio; Yamaguchi, lwao, Hitachi Ltd., Central Research Laboratory

2. Surface Reconstruction of Complex Contour Lines by Means of Chain Code Matching Technique 521Jiang, Xiao Tong; Shu, Hua Zhong; Toumouhn, Christine, Gu, Jia, Luo, Li Ming, Laboratory ofImage Science and Technology

3.3D Representation of Acupoints Based on the Visible Human 525

Zhao, Jing, Zheng, Lei; Zhuang, Tiange; Yan, Zhenguo; Riemer, Martin, Tiede, Ulf, Hfthne, Karl Heinz, Shanghai Jiao tong University

4. Virtual Images of Lung Structures 529

Neves, Leandro A, Frtre, Annie F.; Nascimento, Augusto V , Santos, Clayton E., Universidade de S3o Paulo

5.3D Reconstruction of Coronary Artery using Biplane Angiography 533

Law, Albert K. W, Zhu, Hui, Chan, Francis H. Y., The University of Hong Kong

6. Interactive Virtual Environments for Behavioral Therapy 537

Algorri, Maria-Elena,ITAM

Session 2.2.2: Image Display and Visualization II

Friday Sep-19-2003, 10:30 -12:30 (Coral Gallery, Poster)

1. Base Surface Definition for the Morphometry of the Ear in Phantoms of Human Heads 541

Marquez, Jorge A; Bloch, Isabelle, Schmitt, Francis, CCADET, UNAM

2. Comparison of Eye and Lip Measurements Obtained Using Single and Stereo Photogrammetry 545

Douglas, Tama S ; Memtjcs, Ernesta M.; Vaughan, Christopher L, Viljoen, Denis L, University of Cape Town

3. Projector-Based Augmented Reality in Surgery Without Calibration 548

Tardif, Jean-Philippe; Roy, Sebastien, Meunier, Jean , Universite de Montreal

4. Experimental Optimization of Detector Pixel Size for Stent Visualization in X-Ray Fluoroscopy 552

Jiang, Yuhao; Huo, Donglai, Wilson, David L, Case Western Reserve University

5. Pre-Compcnsation for High-Order Aberrations of the Human Eye Using On-Screen Image Deconvolution 556

Alonso, Jr, Miguel, Barreto, Armando B

, Florida International University

6. A New Method of Image Indexing and Retrieval Using Gabor Wavelet and Legendre Moments 560

Ahmadian, Alneza, Faramarzi, Esmaeil, Sayadian, Abolghasem, Tehran University of Medical Sciences

7. Virtual Images for Assisting the Assessment of X-Ray Equipments 564

Santos, Clayton E, Frere, Annie F ; Silva, Marcia A ; Inta, Ricardo T.; Neves, Leandro A,Universidade dc Sao Paulo

8. Fast Reconstruction of Volumetric Models of Anatomical Structures 568

Archip, Neculai, Rohling, Robert, The University of British Columbia

9. Towards Statistical Inferences of Successful Prostate Surgery 572

McKenzic, Ficdcnc D, Diaz, Jose, Schellhammer, Paul, Hussein, Rama, Old Dominion University

Contents - 9

10. Comparative Study of Two Calibration Methods on Fundus Camera 576

Xu, Juan, Chutatape, Opas, Nanyang Technological University

Track 2.3: Image Segmentation and Registration

Session 2.3.1: Image Registration

Saturday Sep-20-2003, 8:00 -10:00 (Grand Coral 2, Slide)

1. 3D Segmentation and Characterization of Lower Limb Vessels in Multi-Slice Computed Tomography 580

Boldak, Cezaiy, Toumouhn Christine, Coatneux, Jean-Lotus, LTSI, Umversite de Rennes 1

2. Spatio-Temporal Registration in Coronary Angiography 584

Gu, Jia, Toumouhn, Christine, Shu, H, LTSI, Umversite de Rennes 1

3. Multi-Line Matching for Vessel Formation in X-Ray Coronarography: a Comparison of Three Algorithms 588

Bellanger, Jean-Jacques; Bricva, Jorge, Toumouhn, Christine , LTSI - Bat 22 - Umversite de Rennes

4. Automatic Registration and Fusion of High Resolution Micro-Ct and Lung Perfusion Spect Images of the Rat 592

Fei, Baowci; Wietholt, Christian; Clough, Anne V ; Dawson, Christopher A ; Wilson, David L,Case Western Reserve University

5. A Hierarchical Nonrigid Image Registration Technique Based on Local Deformations 595

Castellanos, Norma P., UAMI

6. Optimization Methods for Registration of Multimodal Images of Retina 599

Kubecka, Libor; Skokan, Martin, Jan, Jin, Brno University of Technology

7. Automatic Integration of PET/ct Images for Clinical Use in Radiotherapy 603

Rizzo, Giovanna, Arienti, Roberto, Castigliom, Isabella; Cattaneo, Giovanni M ; Castellone, Pietro; Landoni, Claudio; Ceresoli,

Giovanni; Messa, Cnslina; Gilardi, Mariacarla; Cerutti, Sergio, Fazio, Ferruccio, Italian National Research Council

8.2d and 3D-Superimposition of Cardiac SPECT and Coronarography Data 607

Sanchez, Stiphane, Valet, Gaelle; Lopez-Hemadez, Juan M.; Wolf, Didicr; Daul, Christian; Karcher, Gilles, CRAN - INPL

Session 2.3.2: Image SegmentationSaturday Sep-20-2003, 13:30 -15:30 (Grand Coral 2, Slide)

1. Robust Segmentation of the Left Ventricle from MRI 611

Medina, Veronica; Garza, Maria, Lerallut, Jean-Francois; Meer, Peter; Yanez-Suarez, Oscar; Valdes, Raquel, UAM-lztapalapa

2. Optimal Feature Combination for Automated Segmentation of Prostatic Adenocarcinoma from High Resolution

MRI 614

Madabhushi, Anant, Fcldman, Michael; Metaxas, Dinntris; Chute, Deborah; Tomaszewcski, John, University ofPennsylvania

3. Cortical Gray Matter Segmentation Using an Improved Watershed Transform 618

Grau, Vicente; Kikinis, Ron; Alcaniz, Mariano; Warfield, Simon K., Brigham and Womens Hospital

4. Velocity-Aided Cardiac Segmentation 622

Cho, Jinsoo; Brummer, Marijn; Benkeser, Paul J., Georgia Institute ofTechnology

5. Segmentation of Cardiac MR Images Using the EM Algorithm with a 4D Probabilistic Atlas and a Global

Connectivity Filter 626

Lorenzo-Valdes, Maria, Rueckert, Daniel; Mohiaddin, Raad; Sanchez-Ortiz, Gerardo I., Imperial College

6. Segmenting Cardiac MRI Tagging Lines using Gabor Filter Banks 630

Qian, Zhcn; Montillo, Albert; Metaxas, Dimitris N.; Axel, Leon, Rutgers University

7. Unsupervised Tissue Classification in Medical Images using Edge-Adaptive Clustering 634

Pham, Dzung L, Johns Hopkins University

8. Multiscale Segmentation of the Aorta in 3D Ultrasound Images 638

Krissian, Karl,Harvard Medical School

Session 2.3.3: Image Registration and Segmentation I

Saturday Sep-20-2003, 10:30 -12:30 (Coral Gallery, Poster)

J. New Frameless Patient Positioning Algorithm in Conformal Radiotherapy Using 3D-Data Registration 642

Posada Gomez, Ruben, Daul, Christian, Wolf, Didici,Centre de Recherche en Aulomatiquc de Nancy (INPL)

2. Thrce-Dimensional Automatic Volume Registration of Carotid MR Images 646

Fei, Odown, Zhang, Shaoxiong, Savado, Olivier, Sun, Jasjit, Ixwin, Jonathan S, Wilson, David I., Case Weslcm Reserve University

3. The Generation of Feature Map in High Dimensional Feature Space 649

lie, Renjie, Naiayana, Ponnada A , Univ of Texas Medical School at Houston

Contents - 10

4. A Parabola Fitting Edge Operator by the Moments653

Xu, Danhua, Shu, Huazhong, Bao, Xudong, Zhang, Hui, Dillenseger, Jean Louis; Luo, Limin, Laboratory of Image Science andTechnology

5. Segmentation of Ultrasound Images by Using Wavelet Transform 657Kuma/, Mchmet N

, Dokur, Z, Olmez, r,Istanbul Technical University

6. Eigcnspace Normalization of Multi-Spectral Magnetic Resonance Images 660Valdes-Ciistema, Raquel, Mcdina-Bafiuelos, Veronica, Yartez-Suarez, Oscar, Universidad Autonoma Metropohtana-lztapalapa

7. Computerized Diagnosis of Facial Nerve Palsy Based on Optical Flow Analysis of Facial Expressions 663Minamitani, llaruyuki ,

Kcio University

8. Evaluation of Multiparameter Micrograph Analysis with Synthetical Benchmark Images 667Nattkemper, I im W, Saalbach, Axel, Tv-ellmann, Thorsten, Bielefeld University

9. Movement Quantification during Epileptic Seizures: a New Technical Contribution to the Evaluation of SeizureSemiology 671Cunha, Jo3o Paulo S , Vollmar, Chistian, Li, Zhanjian, Femandes, Jose, Feddersen, Berend, Noachtar, Soheyl, University of Aveiro

10. Segmentation of Microarray CDNA Spots Using Mrf-Based Method 674Demirkaya, Omer, Asyah, Musa H , Shoukn, Mohamed M

, Abu-Khabar, Khaled S, King Faisal Specialist Hospital & Research

Center

11. Monitoring and Modeling of Pupillary Dynamics 678Tilmant, Chnstophe, Sarry, Laurent, Gindre, Guillaume, Boire, Jean-Yves, Faculty of Medicine

12. An EM Framework for Segmentation of Tissue Mixtures from Medical Images 682Liang, Jerome Z ,

State University of New York

13. An Application of Multimodal Image Registration and Fusion in a 3D Tumor Simulation Model 686Zachaiaki.E I, Malsopoulos, G K.Nikita, K S

, Stamatakos, G S .National Technical University of Athens

14. 3D Trajectory Assessment of an IVUS Transducer from Single-Plane Cineangiograms: a Phantom Study 690Shcrknies, Denis, Meumer, Jean, Mongrain, Rosaire, Tardif, Jean-Claude, University of Montreal

,

15. An Efficient Multiscale Approach to Level Set Evolution 694Zhang, Hongmei,, Xi an Jiaotong University

16. Segmentation of Surgical Needles for Fluoroscopy Servoing Using the Insight Software Toolkit (itk) 698

Cleary, Kevin, Ibanez, Luis, Navab, Nassir, Stoianovici, Dan; Patnciu, Alexandra, Corral, Gabnela, Georgetown University Medical

Center

Session 2.3.4: Image Registration and Segmentation II

Saturday Sep-20-2003, 16:00 -18:00 (Coral Gallery, Poster)

1. Automatic Segmentation of Scanning Electron Microscopy Images for Molecular Aggregation Profiling 702Ounque, rabncio, Licks, Vmicius, Jordan, Ramiro, Pattichis, Marios, The University of New Mexico

2. A New Method for Dynamic Road Mapping of Coronary Angiography Cardiac Catheterization Cine Loops 706Shoura, Mohamed S

, Alexandria Univ- Egypt

3. A Novel Endoscopic Image Analysis Approach using Deformable Region Model to Aid in Clincal Diagnosis 710Tjoa, Malta P

, Krishnan, S M ; Zheng, M M , Nanyang Technological University

4. Faster Image Dendrogram Creation: An Efficient Algorithm for the Detection of Tumours in Digital Mammography 714

Nguyen, HungT, University of Technology, Sydney

5. 4-D Active Contour Snake Model for Object Representation from Medical Images 717Rodiiguez-Asomoza, Jorge, Rosas-Romero, R., Universidad de las Americas, Pucbla

6. An Image Processing Method for Improved Pupil Size Estimation Accuracy 720

Kim, Jicun, Park, Kyungmo , Kyunghee University

7. MR Brain Image Segmentation Using an Enhanced Fuzzy C-Mcans Algorithm 724

Szilagyi, Uszlo, Bcnyo, Zoltan, Szilagyi, Sandor M , Adam, Hatem S, Budapest Univ ofTechnology and Economics

8. Registration of Brain MRI of Patients with a Tumor 727

Gon/alc/, Ailuro, Marroquin, Jose Luis, Bolello, Salvador, Calderon, Telix, Valdes, Pedro, Aubel, Eduardo, Bosch, Jorge, Fcrnandcz-

lkiu/as, Antonio, Harmony, rhaha, CIMAT

9. Pattern Analysis Of Cell Mlcronuclei Images To Evaluate Their Use As Indicators Of Cell Damage 731

I o/anc), Antonio, Maiquc/, Joigc A Buenfil, Ana L,Gonsebatt, Mana E , CCADET, UNAM

10. Hough Transform Based Method for Air Bubbles and Oil Drops Segmentation in Dispersions Ocurring in Stirred

Biorcactors '"

Vega-Alvarado, 1 ctiua, Taboada, Blanca, Galindo, Enrique, Corkidi, Gabnel, instituto de Biotecnologla-UNAM

Contents - 11

11. Object Tracking in Medical Imaging Using a 2D Active Mesh System 739

Lautissier, J6r6mc, Legrand, Louis, Lalande, Alain, Walker, Paul, Brunotte, Francois, UFR Mcdccinc

12. A Semi-Automated Algorithm for Quantification of Vessel Wall Angiogencsis Associated with Early Atherosclerosis

Using Magnetic Resonance Imaging 743

Morawski, Anne, Winter, Patrick M, Caruthers, Shelton D

, Williams, Todd A, Allen, John S

, Tuhihop, Ralph W ,I an/a, Gregory

M, Wickline, Samuel A

, Washington University in St Louis

13. Fuzzy Clustering Based Applications to Medical Image Segmentation 747

Shen, S , Sandham, William A, Granat, Malcolm II

, Dempsey, Maty F, Pattcison, James, University ol Stiathclydc

14. A Simplified Fuzzy Connectedness Method Used for Segmentation of Vessel Images 751

Luo, Shuqian , Capital University of Medical Sciences

Track 2.4: Image Filtering, Compression and AnalysisJasjit Sun, Cwru

Session 2.4.1: Image Filtering and Processing

Friday Sep-19-2003, 8:00 -10:00 (Coral Garden II, Slide)

1. Interactive Ellipse Fitting in Ultrasound Images 754

Lamard, Mathieu, Hamitouchc-Djabou, Chafiaa, Develay Monce, Jean Eric, Bressolette, Luc, Roux Christian,CI IU Moivan I .a 1IM

2. Extraction of Temporal Motor Activity Signals from Video Recordings of Neonatal Seizures by Improved Feature

Tracking Methods Based on Translation Motion Models 758

Karayiannis, Nicolaos B, Xiong, Yaohua, University of Houston

3. Joint Analysis of Heart Geometry and Kinematics with Spatiotemporal Active Region Model 762

Wong, Alexandra, Shi, Pengcheng, Liu, Huafeng, Sinusas, Albert, Hong Kong University of Science & Technology

4. Extraction ofTemporal Motor Activity Signals from Video Recordings of Neonatal Seizures by Feature TrackingMethods Based on Rigid Motion Models 766

Karayiannis, Nicolaos B,Sami, Abdul, University of Houston

5. The Trade-Offs Between Manual and Computer-Based Stereology/classification: Application to Estimates of Volume

Fraction 770

Markowitz, Zvi, Loew, Murray H , George Washington University

6. Optimization Method for Isodensity Surface Models Obtained with Electron Microscope Tomography 774Ress, David; Harlow, Mark L, Marshall, Robert M

, McMahan, Uel J, Stanford University

7. Parametric Sensitivity Analysis of Human Respiratory Impedance 778Lorandi, Ludovico, Diong, Bill, Nava, Patricia, Sohs, Francisco, Menendez, Roger, Ortiz, Gabriel, Nazeran, Homayoun, University of

Texas at El Paso

8. Multlscale Denoising and Enhancement of3D Rotational X-Ray Imaging for Percutaneous Vcrtebroplasty 782

Jin, Ympeng; Angelini, Elsa; Mangla, Sundeep, Choi, In Sup, Kemkers, Richard; Timmer, Jan, Lame, Andrew, Columbia University

Session 2.4.2: Image AnalysisThursday Sep-18-2003, 10:30 -12:30 (The Grand Coral Ballroom, Slide)

1. Finding Intersections of Curvl-Linear Structures in Mammograms Using Oriented Local Energy Feature Detection 786Schenk, Veit U B ; Brady, Michael, Oxford University

2. Automatic Counting of Immunocytochemically Stained Cells 790Arambula Cosio, Fernando, Marquez Flores, Jorge A , Padilla Castafleda, Miguel A

, Solano, Sandra, Tato, Patricia, ("CADET, UNAM

3. Corneal Endothelium Analysis by Means of Bayesian Shape Modeling 794

Foracchia, Marco, Ruggen, Alfredo, University of Padova

4. Automatic Classification of Mammography Parenchymal Patterns: a Statistical Approach 798Petroudi, Styliani, Kadir, Timor, Brady, Michael, University of Oxford

5. Spatlal-Textural Medical Image Indexing Based on Vector Quantization 802Ordonez, John R

,GET - ENST Brctagne

6. Design of Gabor Wavelets for Analysis of Texture Features in Cervical Images 806Van Raad, Viara

,The University of New South Wales

7. Detection of Spiculated Lesions in Mammograms 810

Sampat, Mchul P ,Bovik, Alan C, University oflexas at Austin

8. Robust Recovery of Volumetric Cardiac Motion with Physically Constrained ll-lnfty Filtering 814I.o, Edward W B

, Shi, Pengcheng, Liu, Huafeng ,Hie Hong Kong Umveisity ol Science and lc.chnoli>gy

Contents- 12

Session 2.4.3: Image Reconstruction, Compression, Coding and TransmissionThursday Sep-18-2003, 13:30 -15:30 (Coral Gallery, Poster)1. Multi Rate/resolution Control in Progressive Medical Image Transmission for the Region of Interest (roi) Using Ezw 818Dilmagham, Reza S., Ahmadian, A

, Ghavami, M ; Oghabian, M, Aghvami, II, Centre for Telecommunications Research

2. A Subpixel Algorithm for the Reconstruction of Kinematics from Video Sequences in Orthostatic Postural Tests 821Schmid, Maunzio, Conforto, Silvia, Gmnta, Gaetano, D'Alessio, Tommaso, Universita Roma Tre

3. Fast Image Reconstruction Algorithms for Electric Tomography 825Grebennikov, Alexandre I, Benementa Universidad Autonoma de Puebla

4. Fast Scaled Gradient Decomposition Methods for Maximum Likelihood Transmission Tomography 829De Pierre, Alvaro R

, Yamagishi, M,State University of Campinas

5. Study on Medical Ultrasonic Echo Image Compression by Jpeg2000 - Optimization and the Subjective Assessment ofthe Quality-

833Hamamoto, Kazuhiko

,School of IT and Elec

, Tokai University

6. Closed-Form Quality Measures for Compressed Medical Images: Statistical Preliminaries for Transform Coding 837Li, Dunlmg; Loew, Murray, George Washington University

7. Roi Coding with Integer Wavelet Transform and Unbalanced Spatial Orientation Trees 841Cuhadar, Aysegul, Carleton University

8. A Two-Step Method for Compression of Medical Monitoring Video 845Liu, Qiang, Sclabassi, Robert J.

, Scheuer, Mark L.; Sun, Mingui, University of Pittsburgh

9. Secure Medical-Image Transmission Using Independent Component Analysis 849Park, Sungjin; Ham, Frcdnc M., Florida Institute ofTechnology

10. A Lossless Data Embedding Scheme for Medical Images in Application of e-Diagnosis 852Luo, Xuanwen

, Wayne State University

11. A Medical Image Watermarking Scheme Based on Wavelet Transform 856Giakoumaki, Aggeliki, Pavlopoulos, Sotins, Koutsouris, Dimitns, National Technical University of Athens

12. Wavelet-based Compression of Angiography Sequences on a Shared-Memory System 860Moyano.E.; Quiles, F J, Orozco-Barbosa, L., Universidad de Castilla-La Mancha

14. A Novel Method for the Automatic Evaluation of Retinal Vessel Tortuosity 866Gnsan, Enrico, Foracchia, Marco; Ruggeri, Alfredo, University of Padova

Session 2.4.4: Image Processing and AnalysisFriday Sep-19-2003, 16:00 -18:00 (Coral Gallery, Poster)

1. A New Approach to Brain Tumour Diagnosis Using Fuzzy Logic Based Genetic Programming 870Shen, Shan; Sandham, William A ; Granat, Malcolm H ; Dcmpsey, Mary F.; Patterson, James, University of Strathclydc

2. Extraction of Temporal Motion Velocity Signals from Video Recordings of Neonatal Seizures by Optical FlowMethods

874

Karayiannis, Nicolaos B.; Tao, Guozhi , University of Houston

3. Topography-Based Screening for Previous Laser Correction of Hyperopia 878Lahbertc, Jean-Francois, Brunette, Isabelle; Meumer, Jean, Maisonneuve-Rosemont Hospital

4. Filtering of Ultrasound Echo Signals with the Fractional Fourier Transform 882

Bennett, Michael J.; Anderson, Tom; McLaughlin, Steve; McDicken, Norman, University of Edinburgh

5. Characterization of Architectural Distortion in Mammograms 886Ayres, Fabio J.; Rangayyan, Rangaraj M , University of Calgary

6. A Divide Et Impera Strategy for Automatic Classification of Retinal Vessels into Arteries and Veins 890Gnsan, Enrico; Ruggeri, Alfredo, University ofPadova

7. Deep Venous Thrombosis Screening System Using Numerical Measures 894

Guenero, Julian, Salcudean, S E, McEwen, James A ; Masri, Bassam A

, Nicolaou, Savvas, University of British Columbia

8. Distance Transformation Function for Minimization of Differences Between Three Dimensional Objects from

Medical Images 898

Rosas-Romero, Roberto, Rodriguez-Asomoza, Jorge, Universidad de las Amencas-Puebla

9. Detecting the Optic Disc in Retinal Images by Means of a Geometrical Model of Vessel Network 902

Ruggeri, Alfredo, Foracchia, Maico, Gnsan, Enrico, University of Padova

10. Automatic Tracking and Analysis System for Free - Swimming Bacteria 906

I'aboada, Blanca I, Poggio, Sebastian, Camaiena, Laura, Corkidi, Gabriel, IBTdc la UNAM

Contents- 13

11. A Voxel-Based Measure of Discrete Compactness for Brain Imaging 910

Bribiesca, E ; Jimenez, J. R, Medina, V ,

Valdes, R,Yanez, 0 ,

Universidad Autonoma Metropolitana

12. Interpolation of Tomographic Data Using a Self-Similar Approach 914

Asvestas, Pantelis A., Skevofilakas, Marios, Matsopoulos, George K.; Nikita, Konstantma S., National T echmcal University of Athens

13. A Threc-Dimentional Gazing Point Detection System For Communication Analysis 918

Michio, Miyakawa, Takashi, Kosugi , Graduate School of Nngata Umvcrsiry

14. Pupil Edge Detection and Morphological Identification from Blurred Noisy Images 922

lacoviello, D , Censi, F , Lucchetti, M , Calcagnmi, G ,Istiluto Supcriore di Samui

15. An Image Processing and Analysis Systems For Automatic Classification of Cigarette Filter Blockage 926

Stitt, Joseph P, O'Connor, Richard J

, Kozlowski, Lynn T., The Pennsylvania State University

16. An Efficient Texture Classification Algorithm using Gabor Wavelet 930

Ahmadian, Alireza, Mostafa, Akbar, Tehran University of Medical Sciences

17. A Study of the Most Important Image Quality Measures 934

Kinape, Rog^rio M.; Amonm, Mardson F,PUCPR

18. Subtraction of Images for Automatic Determination of Center of the Radiation Field 937

Nascimento, Marcelo Z; Frdre, Annie F ; Marques, Marcio A., Rodngues, Silvia C. M,Universidade de SSo Paulo

19. Chromosome Classification for Karyotype Composing applying Shape Representation on Wavelet Packet

Transform 941

Guimaraes, Leticia V.; Schuck, Jr, Adalberto, Elbem, Alwin, Universidade Federal do Rio Grande do Sul

20. The Simplified Spine Modeling by 3-D Bezier Curve Based on the Orthogonal Spinal Radiographic Images 944

Lin, Hong ,Texas Scottish Rite Hospital

Track 2.5: Functional Imaging

Session 2.5.1: Functional ImagingThursday Sep-18-2003, 16:00 -18:00 (The Grand Coral Ballroom, Slide)

1. Correlations Between Cardiac Data and FMRI Data as a Function of Spatial Frequency and Time 947

McNamec, Rebecca L ; Eddy, William F., Univensty of Pittsburgh

2. Experiment Result and the Evaluation in Block Paradigm and Single Paradigm 951

Takeuchi, Yusuke ,Tokai University

3. Multiresolution Meg (magnetoencephalography) Imaging by Adaptive Beamformer Scanning 955

Hwang, DoSik, University of Utah

4. A New Method for the Quantitative Study of Neurotransmission 959Frenoux, Emmanuelle; Barra, Vincent; Boirc, Jean-Yves; Habert, Marie-Odile

, Faculty of Medicine

5. Detecting Discriminative Functional MRI Activation Patterns Using Space Filling Curves 963Kontos, Despina; Megalooikonomou, V.; Ghubade, N.; Faloutsos, C, Temple University

6. Functional Image on Glucose Metabolism In Brain Using PET with Short Time Scan 967

Kimura, Yuichi, Tokyo Metropolitan Institute ofGerontology

Session 2.5.2: Image Acquisition and ProcessingFriday Sep-19-2003, 16:00 -18:00 (Coral Gallery, Poster)

1. Blood Volume Measurements by Videodcnsitometric Analysis of Ultrasound-Contrast-Agent Dilution Curves 971Mischi, Massimo; Kalker, Ton A.; Korsten, Erik H., Technical University Eindhoven

2. Improving PET Image Spatial Resolution by Experimental Measurement of Scanner Blurring Properties 975De Bcmardi, Elisabetta, Zito, Felicia, Michclutti, Luisa; Mainardi, Luca, Gerundim, Paolo, Baselli, Giuseppe , Polytechnic Universityof Milano

3. Small-Field Angiographic Imaging ofTumor Blood Vessels in Rabbit Auricle Using X-Ray Saticon Camera and

Synchrotron Radiation 978

Umelam, Kciji, Yainashita, Takenon, Machara, Nobunao, Tokiya, Ryoji, Imai, Shigcki, Kajihara, Yasumasa, Japan SynchrotronRadiation Research Institute

4. Results of an Eit Prototype Able to Supply Static Images 982da Silva, Bruno L P

, Avila, Flavio R, Sou/a, Marcio N , Federal University of Rio de Janeiro

5. A New Information-Theoretical Model for the Performance Evaluation in Breast Cancer Imagery 986Grutiwald, Sonn, Neagoe, Victor-Emil, 7.0NARE Medical Systems Inc

6. A Computer Simulation System of the Electric Activity in Brains 990

Wu.Qmg, Wang, 1 ei, I i, Ying, lie, Shijuan, Yan, Weill, llebei University of! echiiology

Contents - 14

7. The Electrical Properties of Real Head Model Based on Electrical Impedance Tomography 994Xu, Guizhi, Yang.Qingxin, li, Ying, Wu.Qmg, Yan, Weill, Hebei University of Technology

8. Design of a Dual-Modality, Digital Positron Emission Tomography/Computed Tomography (PET/CT) Scanner forSmall Animal Imaging

oggFontaine, Rcjcan, Michaud, Jean-Baptiste, Belangcr, Francois, Cadoiette, Jules; Leroux, Jean-Daniel, Pratte, Jean-Francois, Robert,Stefan, 1 ecomlc, Roger, Utmersuy of Shcrbrooke

9. Predicting the Effect of Film Processing on Optical Density Formation by Computer Simulation 1002Silva, Marcia A

, frere, Annie F., Araki, A T , Universidade dc Mogi das Cruzes

10. Independent Component Analysis for Processing of Retinal Responses to Patterned Stimuli 1006Barriga, E S., fso, D Y

, Pattichis, M S,Soliz, P

,The University of New Mexico

Track 2.6: Optical, Microwaves and other Imaging ModalitiesStephen Boppart, University of Illinois at Urbana-Champaign

Session 2.6.1: Optical, Microwaves and Other Imaging Modalities I

Saturday Sep-20-2003, 8:00 -10:00 (Grand Coral 1, Slide)

1. Image Reconstruction of Eit Using Differential Evolution Algorithm 1011Li, Ying; Rao, Liyun, He, Renjie, Xu, Guizhi, Wu, Qing, Ge, Manling; Yan, Weill, Hebei University of Technology

2. Nonparametric Analysis of Time-Resolved Fluorescence Data Based on the Laguerre Expansion Technique 1015Jo, Javier A.; Fang, Qiyin, Papaioannou, Thanassis, Marcu, Laura

, Cedars-Sinai Medical Center

3. Multi-Spectral Light Interaction Modeling for Imaging of Skin Lesions 1019Dhawan, Atam P., Patwardhan, Sachm V., Reluc, Patricia A

,NJIT

4. Conductivity and Current Density Image Reconstruction in Mreit Using Harmonic BzAlgorithm and RecessedElectrodes

1023Woo, Eung Je

, Kyung I lee University

5. Mueller Matrix Imaging for Cancer Detection1027

Baldwin, Angela M , Chung, J. R.; Baba, J S., Spiegelman, C. H.; Amoss, M. S ; Cot6, G. L,Texas A&M University

6. Chirip Pulse Microwave Computed Tomography(CP-MCT) Equipped with a Fan Beam Scanner for High-SpeedImaging of a Biological Target 1031Miyakawa, Michio, Harada Emiko, Wu, Jing, Nngata University

Session 2.6.2: Optical, Microwaves and Other Imaging Modalities II

Saturday Sep-20-2003, 10:30 - 12:30 (Coral Gallery, Poster)

1. Extraction of Temporal Motor Activity Signals from Video Recordings of Neonatal Seizures by Feature TrackingMethods Based on Dcformable Motion Models 1035Kaiayiannis, Nicolaos B., Xiong, Yaohua, University of Houston

2. Inverse Problem Solutions for Contactless Conductivity Imaging 1039Tek, Mchmet N., Shafai, Bahram, Northeastern University

3. Application of Combined Methods of Imaging in Minimally Invasive Surgery 1043Cysewska-Sobusiak, Anna, Sowier, Aleksander; Skrzywanek, Pawel, Poznan University of Technology

4. Simultaneous Measurement of Ciliary Beat Frequency and Wave Disorder on Respiratory Epithelial Cells 1047

Yi, Won-Jin; Park, Kwang-Suk; Lee, Chul-Hee, Rhee, Chae-Seo, College of Medicine, Seoul National University

5. Usefulness of Ultrasonic Strain Measurement-Based Mechanical Properties Imaging Technique - TowordRealization of Combined Short Time Diagnosis/treatment 1050Sunn, Chikayoshi .Sophia University

6. Rbc Flow Imaging and Po2 Measurement in Cerebral Microcirculation: Effect of Hemodilution on Oxygen Supply to

Brain Cortical Arterioles 1054Arai, I'atsuya ,

Kcio Univcrsily

7. X-Ray Micro-Computed Tomography System: Novel Applications in Bone Imaging 1058

I also'n, 1-arry, Kuban, Barry; Bryan, Jason; Siredney, Don, Davros, William, Midura, Ron, Apte, Suneel, Powell, Kim, Cleveland

Clinic I oundalion

8. Speckle Noise Reduction and Segmentation on Polarization Sensitive Optical Coherence Tomography Images 1062

Choi, llyohoon, Milner, Thomas E, Bovik, Alan C

, University ofTexas at Austin

9. Precision Constant Current Source for Electrical Impedance Tomography 1066

I ee, Jcong Whan, Kyung I lee University

Contents- 15