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COMPANY CONFIDENTIAL COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC ORBITAL THERAPY, LLC

COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

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Page 1: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

Design Review MeetingMay 16, 2007

ORBITAL THERAPY, LLCORBITAL THERAPY, LLC

Page 2: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

AGENDAAGENDA

OrganizationOrganization

MammoKnife ProjectMammoKnife Project

ClearVue ProjectClearVue Project

Discussion PointsDiscussion Points

Physics ReviewPhysics Review

Page 3: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

Garage days are over….Garage days are over….

Page 4: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

8 Alfred Circle, Bedford MA8 Alfred Circle, Bedford MA

Page 5: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

Recent AdditionsRecent Additions

Natalya Koshnitsky – Regulatory & Marketing

Chas Burr – Regulatory Affairs (Quality Systems)

Michael Barenboym – Mechanical Engineering/ Industrial Design

Page 6: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

AGENDAAGENDA

OrganizationOrganization

MammoKnife ProjectMammoKnife Project

ClearVue ProjectClearVue Project

Discussion PointsDiscussion Points

Physics ReviewPhysics Review

Page 7: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

UpdateUpdate

Linear Accelerator• LOI received from Siemens• Mevex (Ottawa) interested in working with us

Multi-Leaf Collimator• Radionics MLC not ideal (old technology, wrong geometry)• Topslane coming for a visit on Monday• Buy vs. Make decision to be made this Quarter

Shielding Experiment• Design completed• Fabrication under way• Experiment scheduled for June at NEVOG (Waltham)

Page 8: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

Design SelectedDesign Selected

MammoKnifeTM

Page 9: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

PRODUCTPRODUCT

MammoKnifeTM

Page 10: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

AGENDAAGENDA

OrganizationOrganization

MammoKnife ProjectMammoKnife Project

ClearVue ProjectClearVue Project

Discussion PointsDiscussion Points

Physics ReviewPhysics Review

Page 11: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

MARKETMARKETEmergence of Prone-Based RT Table TopsEmergence of Prone-Based RT Table Tops

Page 12: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

CLEAR-VUECLEAR-VUE

Page 13: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

CLEAR-VUECLEAR-VUEErgonomic Design Table

Page 14: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

AGENDAAGENDA

OrganizationOrganization

MammoKnife ProjectMammoKnife Project

ClearVue ProjectClearVue Project

Discussion PointsDiscussion Points

Physics ReviewPhysics Review

Page 15: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

Field SizeField Size

Maximum Field Size

Y = ?

X = ?

Page 16: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

MLC QuestionsMLC Questions

• Leaf resolution at isocenter?

• Leaf material W vs. ???

• Overtravel – how much?

• Desired Penumbra?

Page 17: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

EnergyEnergy

4MV vs. 6MV

Page 18: COMPANY CONFIDENTIAL Design Review Meeting May 16, 2007 ORBITAL THERAPY, LLC

COMPANY CONFIDENTIALCOMPANY CONFIDENTIAL

AGENDAAGENDA

OrganizationOrganization

MammoKnife ProjectMammoKnife Project

ClearVue ProjectClearVue Project

Discussion PointsDiscussion Points

Physics ReviewPhysics Review