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Off.: Plot-36, Shramsafalya, RSC -11, Veer Savarkar Nagar, Thane (W) – 400606 Maharashtra (INDIA). Tel.: 91- 22 – 2582 8524, 0250-6454728/29 Telefax: 91 – 22 -2583 3896 Website: Email: [email protected] www.paanpharmatech.com Pharmatech Engineers Pvt. Ltd. PAAN Pharmatech Engineers Pvt. Ltd. PAAN RAPID MIXER GRANULATOR I. Salient Features for production scale ? ? ? ? ? ? ? ? ? ? Homogeneous binder distribution. Short batch time and reduce cleaning time. Maximize CIP effectiveness. Air purging system for both agitator. PLC based operating panel for precise control of process automation. A high-speed granulator is to assist blending of powder and to break the product to the granules of required size All moving parts of the machine are totally enclosed. The machine cannot be started unless and until the mixer cover is properly closed. All contact parts are made out of SS316. Geometrically bowl and impeller shall be same so as to set all mixing parameters as per R&D version. DESCRIPTIONS The PAAN'S RMG working principle is based on two decisive factors essential for the mixing systems. Rapid Mixer Granulator was developed in close co-operation with pharmaceutical industry. With the help of RMG wet sifting is generally no longer necessary. After the mixing of the dry components, subsequent wet granulation occurs (without transfer of dry mixture) producing loose granules in RMG. Better mixing and closed control of granule size leads to faster tableting speeds with improved quality and least rejections. Dry mixing and Wet Granulating in the same bowl in only few minutes. The entire operation including discharge is fully automatic. Spinning close to the bottom of the mixing bowl. The impeller sets the entire mixture in a whirling-rising tumbling motion ensuring a quick and even distribution of all dry components, which leads to an even wetting of every granule. The large lumps occurred during wet mixing are broken up, by the strategically located chopping tool rotating at 1440/2880 RPM. The mix can be discharged with the impeller through the outlet flush to the bottom. The mixing tool is easily removed. II. Salient Features for Lab scale ? ? ? ? ? ? Portable self contained unit, Process flexibility. Quick changeover for all parts without any tools. Interchangeable bowl facility, speed regulator for chopper and main anchor. Optional- I) Solution addition facility, II) Jacketed. Geometrically well engineered shape and beater. PLC control system in R&D unit which will be very easy for scale up the production.(all parameters are well defined at R&D level). MODEL C-BD 20 C-BD 30 Product inlet DIA 10'’ 12’’ Throut inlet DIA 8’’ 12’’ Product outlet DIA 12’’ 20’’ Screen Round hole type Round hole type Impeller Standard Standard Drive 5 kw 1500 rpm motor with gear 10 hp 1100 rpm motor with gear Output (kgs / hrs) 100 -1200 250 - 3000 Discharge Quick release, swing away, collar at discharge end for easy bag fixing, grid mesh for added safety protection. Spindle Assembly Sanitary pharmaceutical GMP grade, pre lubricated sealed bearing viton O-ring, two shaft seal & single leap seal in SS 316 casing it can be used for Vacuum application. MOC Contact parts SS 316 & Non contact parts Ss304 Finish Non contact parts -150 Grit (RA 1.06) Contact parts- 300 Grit (RA 0.53) TECHNICAL SPECIFICATION FOR BOTTOM DRIVEN Cone Mill is suitable for dry granulation & wet granulation. To satisfy the need of size reduction, conical screen mill concept is developed. The key to the co-mill's superior performance is, the engineered combination of low velocity operation and the highly evolved design & geometry of the conical screen & impeller.(i.e. milling components) DESCRIPTIONS CONEMILL BOTTOM-DRIVEN BOTTOM DRIVEN HSMG (RMG) ? ? ? ? ? ? ? ? ? ? ? ? ? F so bet n f re a l t sa ro ssem ully cu t miza l o ma y dif e nt pp ica ion ndp ce s tr a s. p dd i nal w i h re y t at n ro c Low s ee es g lo ing for n e ntl gen le c ion o the p du t sln i t m ail ra l ri re u ti g n Op imu p rtceg nu a ty. Hi hc a i sc sse ih u t dp u g ap cite on i t nt, hg -q aliyen rod ct o h e o c le t re ci n a sn ie Lw eat gen rati n, ex e l n for size du to of he t e sit v pou i n u a a r d ct n de se h mid re . Ca v d s , oc kn a ig olm nbeo er o edn ho i g &j mmn pr be . o ie e, ii u L w nos lev l l d t ni n na fri n mnm m ro ow us- e vro me t l e dly p duct ls o s. g e p ut te tio c s t p r c n Ne ligibl rod c re n n with on isten erfo man e a d p t y re ea abilit . Es p rai n s la, o i te n , q s e a y for o e to - ea y ce n l w man na ce uick cre n a v ch ngeo er. l bl y – Ca ct n ail i tr ti n a aa o Sca a i it pa iies a d p rtce size ds ibu o re sc l ble t l rg ui a er n ts. ag di ete R s 0 h c a a L r e feed am r e ults in to 5 % hig er ap city th n ov t a ie c n en ion l mach n s. S fp d ta e / c sn a uai nat r izingo ro uc ft r FBD pro es i gwet gr n l to f e RMG. l A se &i p e em ehg g q ym A l PA N i ves m ell r ar ad i h rade ualit aterial. bs u ts a t e re n o i i te d For e t res l g p be we n sc en a d r tor s ma n ne . FEATURES ? ? ? ? Gr r ou e zi g & si f w anulation of d y powders for s l bl s, si n Uniform zing o et ulation actu gran in tablet manuf ring. S uci an ng d pr ize red ng d milli of wet or soake oducts to produce liquid ih et nde ar w t W suspe d p ticulates. ge & e l nding e is em Lump-free homo neous w t b e to pr c e size requir ents. i , ve e nt Reducing d fficult, sticky heat-sensiti agglom rates i o pieces, m ntinu e ive cru bs or powders of uniform size, co ously without exc ss at i or scr a he bu ld-up een block ge. T P CA A PL CATI S YI L P I ON Compliance certificates & DQ, IQ, OQ. Documents are available to make your validation process easier. Documentation The Bottom-driven PAAN CONEMILL is based on the same technology as the Top-driven. It has the same capabilities as the Top-driven PAAN CONEMILL with some additional benefits. It has a compact, inline design, which allows for easy integration into processing environments where head room is limited. It is available in three models which are scalable in capacity up to 1800 kg/hr. PRODUCT DESCRIPTION

CONEMILL BOTTOM-DRIVEN RAPID MIXER GRANULATOR · 2019. 11. 5. · TE CHN IAL SP FON R BOTTOM DRIVEN Cone Mill is suitable for dry granulation & wet To satisfy the need of size reduction,

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Page 1: CONEMILL BOTTOM-DRIVEN RAPID MIXER GRANULATOR · 2019. 11. 5. · TE CHN IAL SP FON R BOTTOM DRIVEN Cone Mill is suitable for dry granulation & wet To satisfy the need of size reduction,

Off.: Plot-36, Shramsafalya, RSC -11, Veer Savarkar Nagar, Thane (W) – 400606 Maharashtra (INDIA).

Tel.: 91- 22 – 2582 8524, 0250-6454728/29 Telefax: 91 – 22 -2583 3896

Website: Email: [email protected]

Pharmatech Engineers Pvt. Ltd.PAAN

Pharmatech Engineers Pvt. Ltd.PAAN

RAPID MIXER GRANULATOR

I. Salient Features for production scale

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Homogeneous binder distribution.

Short batch time and reduce cleaning time.

Maximize CIP effectiveness.

Air purging system for both agitator.

PLC based operating panel for precise control of

process automation.

A high-speed granulator is to assist blending of

powder and to break the product to the granules of required size

All moving parts of the machine are totally

enclosed.

The machine cannot be started unless and until the

mixer cover is properly closed.

All contact parts are made out of SS316.

Geometrically bowl and impeller shall be same so

as to set all mixing parameters as per R&D version.

DESCRIPTIONS

The PAAN'S RMG working principle is based on two decisive factors essential for the mixing systems. Rapid Mixer Granulator was developed in close co-operation with pharmaceutical industry. With the help of RMG wet sifting is generally no longer necessary. After the mixing of the dry components, subsequent wet granulation occurs (without transfer of dry mixture) producing loose granules in RMG.

Better mixing and closed control of granule size leads to faster tableting speeds with improved quality and least rejections. Dry mixing and Wet Granulating in the same bowl in only few minutes. The entire operation including discharge is fully automatic.

Spinning close to the bottom of the mixing bowl.

The impeller sets the entire mixture in a whirling-rising tumbling motion ensuring a quick and even distribution of all dry components, which leads to an even wetting of every granule. The large lumps occurred during wet mixing are broken up, by the strategically located chopping tool rotating at 1440/2880 RPM. The mix can be discharged with the impeller through the outlet flush to the bottom. The mixing tool is easily removed.

II. Salient Features for Lab scale

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Portable self contained unit, Process flexibility.

Quick changeover for all parts without any tools.

Interchangeable bowl facility, speed regulator for

chopper and main anchor.

Optional- I) Solution addition facility, II) Jacketed.

Geometrically well engineered shape and beater.

PLC control system in R&D unit which will be very

easy for scale up the production.(all parameters are well defined at R&D level).

MODEL C-BD 20 C-BD 30

Product inlet DIA 10'’ 12’’

Throut inlet DIA 8’’ 12’’

Product outlet DIA 12’’ 20’’

Screen Round hole type Round hole type

Impeller Standard Standard

Drive 5 kw 1500 rpmmotor with gear

10 hp 1100 rpmmotor with gear

Output (kgs / hrs) 100 -1200 250 - 3000

Discharge Quick release, swing away, collar atdischarge end for easy bag fixing, gridmesh for added safety protection.

Spindle Assembly Sanitary pharmaceutical GMP grade, prelubricated sealed bearing viton O-ring, twoshaft seal & single leap seal in SS 316casing it can be used for Vacuum application.

MOC Contact parts SS 316 & Non contact parts Ss304

Finish Non contact parts -150 Grit (RA 1.06)

Contact parts- 300 Grit (RA 0.53)

TECHNICAL SPECIFICATION FORBOTTOM DRIVEN

Cone Mill is suitable for dry granulation & wet

granulation. To satisfy the need of size reduction,

conical screen mill concept is developed.

The key to the co-mill's superior performance is,

the engineered combination of low velocity

operation and the highly evolved design &

geometry of the conical screen & impeller.(i.e.

milling components)

DESCRIPTIONS

CONEMILL BOTTOM-DRIVEN

BOTTOM DRIVEN HSMG (RMG)?

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F s o b e t n f re a l t s a ro s s e mully cu t miza l o ma y dif e nt pp ica ion nd p ce s tr a s.

p d d i n a l w i h re y t a t n ro cLow s ee es g l o ing for n e ntl gen le c ion o the p du t

s l n i t m a i l ra l rire u ti g n Op imu p rt c e g nu a ty.

Hi h c a i s c s s e i h u t d p ug ap cit e on i t nt, h g -q ali y en rod ct

o h e o c l e t re c i n a s n i eL w eat gen rati n, ex e l n for size du t o of he t e sit v

p o u i n u a ar d ct n de se h mid re .

Ca v d s , o c k n a i g o l mn be o er o ed n ho i g & j mm n pr b e .

o i e e , i i uL w no s lev l l d t n i n n a fri n m n m m roow us - e v ro me t l e dly p duct

l so s.

g e p u t te tio c s t p r c nNe ligibl rod c re n n with on isten erfo man e a d

p t yre ea abilit .

E s p ra i n s l a , o i te n , q s ea y for o e t o - ea y c e n l w ma n na ce uick cre n

a vch ngeo er.

l b l y – Ca c t n a i l i tr ti n a a a oSca a i it pa i ies a d p rt c e size d s ibu o re sc l ble t

l rg u ia er n ts.

a g di ete R s 0 h c a aL r e feed am r e ults in to 5 % hig er ap city th n

o v t a i ec n en ion l mach n s.

S f p d t a e / c s n a u a i n a t r izing o ro uc ft r FBD pro es i g wet gr n l t o f e RMG.

l A s e & i p e e m e h g g q y mA l PA N i ves m ell r ar ad i h rade ualit aterial.

b s u ts a t e re n o i i te dFor e t res l g p be we n sc en a d r tor s ma n ne .

FEATURES

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?

Gr r o u e zi g & si f w anulation of d y powders for s l bl s, si n Uniform zing o et

ulation actugran in tablet manuf ring.

S uci an ng d prize red ng d milli of wet or soake oducts to produce liquid

i h et nde arw t W suspe d p ticulates.

ge & e l nding e is emLump-free homo neous w t b e to pr c e size requir ents.

i , ve e ntReducing d fficult, sticky heat-sensiti agglom rates i o pieces,

m ntinu e ive cru bs or powders of uniform size, co ously without exc ss

at i or scr ahe bu ld-up een block ge.

T P CA A PL CATI S Y I L P I ON

Compliance certificates & DQ, IQ, OQ.

Documents are available to make your

validation process easier.

Documentation

The Bottom-driven PAAN CONEMILL is based on the same

technology as the Top-driven. It has the same capabilities as

the Top-driven PAAN CONEMILL with some additional

benefits.

It has a compact, inline design, which allows for easy

integration into processing environments where head room

is limited.

It is available in three models which are scalable in capacity

up to 1800 kg/hr.

PRODUCT DESCRIPTION

Page 2: CONEMILL BOTTOM-DRIVEN RAPID MIXER GRANULATOR · 2019. 11. 5. · TE CHN IAL SP FON R BOTTOM DRIVEN Cone Mill is suitable for dry granulation & wet To satisfy the need of size reduction,

CONEMILL(Innovative Sieving & Milling Technology)

MODEL C-TD 01 C-TD 02 C-TD 03 C-TD 04

Product inlet DIA 10'’ 14'’ 20’’ 15'' x 22'’

Throut inlet DIA 3’’ 6’’ 8’’ 11’’

Product outlet DIA 6’’ 10’’ 14’’ 26’’

Screen Round hole type Round hole type Round hole type Round hole type

Impeller Standard Standard Standard Standard

Drive 2 hp 1440 rpmmotor with timingbelt & pulley

5 hp 1440 rpmmotor with timingbelt & pulley

10 hp 1440 rpmmotor with timingbelt & pulley

20 hp 1440 rpmmotor with timingbelt & pulley

Output (kgs / hrs) 50 – 450 100 – 1000 200- 1800 300 -2000

Discharge Quick release, swing away, collar at discharge end for easy bag fixing,grid mesh for added safety protection.

Spindle Assembly Sanitary pharmaceutical GMP grade, pre lubricated sealed bearing viton O-ring, twoshaft seal & single leap seal in SS 316 casing it can be used for Vacuum application.

MOC Contact parts SS 316 & Non contact parts Ss304

Finish Non contact parts -150 Grit (RA 1.06)

Contact parts- 300 Grit (RA 0.53)

TECHNICAL SPECIFICATION FOR TOP DRIVEN

CONEMILL TOP-DRIVEN

Control Panel is made up of S. S. sheet metal.

It is with special feature DISPLAY SYSTEM and MICROPROCESSOR with member keys.

Display system consists of indicator lamps for compressed air supply, main motor, chopper motor, bowl lid limit switch and for closed / open status of discharge valve.

In case of insufficient compressed air supply pressure switch contained in the panel will prevent the machine from starting.

Limit switch is provided on main bowl lid, and discharge valve, which will de-energies the system when the lid is open.

CONTROL PANEL

TOP DRIVEN HSMG (RMG)

Top driven High shear mixing granulator is most suitable for dry and wet granulation. Main features are easy cleaning & maintenance so user-friendly. Faster processing time with interchangeability bowl facility allows increasing more productivity with consistent quality .

The SS bowl has no seals, blades or crevices and can be

easily cleaned.

The mixing arm and chopper are top mounted and do not

require to be opened for cleaning. Vertical-Shaft Chopper for Improved Granulation.

Small amount of air is required to purge seals located above

the product hence pressure builds up and aeration is minimised.

Space saving.

The mixing and chopper drives use hydraulic motor instead

of electric motors, thereby drastically reducing the HP load and power consumption and do not require VFD.

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ADVANTAGES

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Constant Power Transmission efficiency, Reduced

Power cost: Hydraulics is a very efficient Power transmission system. We use the unique power matching design; in such a system the torque delivery varies with different Anchor speed, hence optimizing the installed power, subsequently, a huge saving in power cost.

Hydraulic transmission is low noise.

Hydraulic Transmission is shock absorbing; this

reduces maintenance.

Hydraulic drive is a direct drive system, such a power

train eliminates gearbox, pulleys/v belts, sprocket/chain,

and this feature reduces a huge maintenance concern.

The Power to weight ratio of Hydraulics is excellent,

this reduces the typical machine weight.

Hydraulic component: a) Average life expectancy,

particularly in this application is as high as 10 to 15 years.

b) Changing is very easy. c) Are reasonably priced and

most components commonly available in the open market.

SPECIFIC ADVANTAGES OF USING HYDRAULIC DRIVE OVER ELECTRIC DRIVE

The Top-driven PAAN CONEMILL is used for a wide range of

products and applications. It can be used for mixing and

dispersing, size reducing, separating and reclaiming, and

bulk density adjustment in pharmaceutical, food and

chemical industry.

The typical particle size distribution (PSD) is tightly contained

with the 125 micron to 1000 micron range (120 mesh to

18 mesh), depending on the screen and impeller

choices. Traditional milling technologies do

not have the same control over the PSD

resulting in more fines and a flatter curve

and less control over quality and

repeatability.

PRODUCT DESCRIPTION

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Portable self contained unit for R&D.

Quick changeover for all parts without any tools.

Process flexibility. Interchangeable bowl facility, Mixer

and Chopper blade speed is well defined.

Integrated Storage Area for spares for R&D models.

Optional- I) Solution addition facility, II) jacketed facility.

Geometrically well engineered bowl and beater shape.

PLC control system can be offered in R&D unit which

will be very easy for scale up the production (all parameters are well defined at R&D level) Multiple end-point detection parameters:a.) Mixer Powerb.) Granulation Timec.) Solution Amount Delivered

Homogeneous binder distributiona.

Short batch time and reduce cleaning time. Maximize CIP

effectiveness.

The seal housing and drive shaft may be flushed with

cleaning water, which is then drained away from the machine through built in drain tubes.

All moving parts of the machine are totally enclosed.

The machine cannot be started unless and until the

mixer cover is properly

Contact parts are made out of Ss316. All internal contact

parts are polished to the mirror finish.

Flush wall type discharge valve eliminates pockets at

the port of discharge valve.

Geometrically bowl and impeller shall be same so as to

set all mixing parameters as per R&D equipment.

SALIENT FEATURES

PLC CONTROL SYSTEM

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Multiple End-Point Detection Parameters

Mixer Power

Granulation Time

Solution Amount Delivered

Data Collection Port to PC or Printer (Optionalz