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Copyright 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Principles of Pharmacology The Pathophysiologic Basis of Drug Therapy Slide 2 Copyright 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 6 Pharmacogenomics Chapter 6 Pharmacogenomics Slide 3 Copyright 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins CYP2D6 Pharmacogenetics Figure 6-1 Slide 4 Copyright 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Tamoxifen Pharmacogenetics Figure 6-2 Slide 5 Copyright 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins TPMT Pharmacogenetics Figure 6-3 Slide 6 Copyright 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Warfarin Pharmacokinetics and Pharmacodynamics Figure 6-4 Slide 7 Copyright 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Genome-Wide Association Study of Statin-Induced Myopathy Figure 6-5