Thursday, August 3, 2017 • APG News B7

DID YOU KNOW?

Born Aug. 3, 1922, John Sheldon DoudEisenhower was the second child of Dwight D.Eisenhower and his wife, Mamie. Their oldest child,a son named Doud, died of scarlet fever at age 3.John Eisenhower served in the Army like his fatherand was a cadet at West Point, graduating June 6,1944, the day of the Normandy landing.

Eisenhower served during World War II and theKorean War, and then left active duty in 1963 toserve in the Army Reserve until his retirement in1975. Though he attained the rank of brigadiergeneral and earned several awards anddecorations, Eisenhower felt his career wasthwarted by concerns for his safety. He felt leadersdid not want his death or capture to distract hisfather, who was the Supreme Allied commander.He protested profusely, when while serving in Koreaas a major in 1952, he was reassigned from acombat unit to a desk job while his father ran forPresident and he shared his feelings in a 2008“New York Times” opinion piece titled, “PresidentialChildren Don’t Belong in Battle.”

During his father’s presidency, John Eisenhowerserved as Assistant Staff Secretary in the WhiteHouse, on the Army’s General Staff, and in theWhite House as assistant to NATO Supreme AlliedCommander Gen. Andrew Goodpaster.

He later served in the administration of PresidentRichard Nixon, who was his father’s Vice President,and as the 45th U.S. Ambassador to Belgium. Inaddition, President Nixon appointed EisenhowerChairman of the Interagency Classification Review

Committee in 1972 and in 1975 he served PresidentGerald Ford as chairman of the President’sAdvisory Committee on Refugees.

Eisenhower and his wife, the former BarbaraJean Thompson, had four children:

Dwight David Eisenhower II, born 1948, apresidential grandson who married Julie Nixon,herself a presidential daughter; (Barbara) AnneEisenhower born 1949; Susan Elaine Eisenhowerborn 1951; and Mary Jean Eisenhower, born 1955.

John Eisenhower and his wife divorced in 1986

after 39 years together. In 1988, Eisenhowermarried Joanne Thompson. They lived in Trappe,Maryland, where he died Dec. 21, 2013. He is buriedon the grounds of the U.S. Military Academy atWest Point. From the death of John Coolidge in2000 until his own death, Eisenhower was theoldest presidential child.

Eisenhower was the author of several books,which included “The Bitter Woods,” a study of theBattle of the Bulge, and “So Far from God,” a historyof the U.S.-Mexican War.

The son of President DwightEisenhower rose to the rank ofbrigadier general, served in theadministration of President RichardNixon and as U.S. Ambassador toBelgium.

This photo of John Eisenhower was taken during a 1990tour of the nulear-powered aircraft carrier USS Dwight D.Eisenhower (CVN 69), which was named for his father, theformer president.

COURTESY PHOTO

Johns Eisenhower’s son, David, at age 12, poses at thepresidential retreat in Western Maryland that was namedfor him and his great-grandfather by his grandfather, Presi-dent Dwight D. Eisenhower.

COURTESY PHOTO

narcotic usage and the defense communi-ties. Feasel has proposed studies at ECBCto research such effects of removing thedrug from cell receptors using substancessuch as naloxone.

“Higher potency versions of naloxoneare available, however the Food and DrugAdministration has not seen a need to getthem approved for human use, until now.These ultra-potent opioid exposures arenot only a chemical defense issue, but theyare also a public health issue,” Feaselreported.

Feasel, who recently received a Ph.D. intoxicology at the University of Maryland,Baltimore School of Medicine, ap-proached principal investigator MarilynA. Huestis, Ph.D., then-chief of chemistryand drug metabolism at the NationalInstitute on Drug Abuse’s (NIDA) Intra-mural Research Program about a collabo-ration on identifying carfentanil metabo-lites.Huestis recognized the epidemic andneed to research carfentanil, and agreed tocollaborate with Feasel and Robert Kris-tovich, Ph.D., ECBCMolecularToxicologybranch chief.

Feasel worked in NIDA’s labs for weeksincubating hepatocytes, commonly re-ferred to as human liver cells, in atwo-dimensional (2D) platform. Twelvemetabolites were identified in total andthe hepatocyte incubations showedslower clearance, providing some insightinto the duration of carfentanil’s effects onthe human body. Recent biological studieshave shown cells forming on their ownadhere to each other forming spheroids.Feasel conducted a follow-on study incu-bating carfentanil with three dimensional(3D) liver spheroids. In this instance thespheroids closely resembled ahuman liverorgan versus the 2D platform which wassimilar to an individual cell. “Byusing a 3D

subculture we are enabling the access torealistic data or in vivo metabolism,”observed Feasel.

Conclusions on this study have not yetbeen made as Feasel and his team are inthe process of analyzing the data.

As carfentanil continues to make head-lines the research being done at ECBC isvital as more information is brought tolight about the substance.

“My goalwith this studywas to not onlyto understand this opioid, but to also bring

the process and techniques of generatingmetabolite libraries to ECBC” remarkedFeasel. “ECBC could apply the techniqueto unknown compounds which may be ofinterest to the CB defense community.”

ECBCFrom page B1

Dr. Mike Feasel (right) and Acting Edgewood Chemical Biological Center Director Dr. Eric Moore discuss effects of carfentanil exposureand its relation to warfighters.

U.S. ARMY PHOTO

administrative data systems analysis. Thepurpose of the survey and administrativedata analysiswas to identify thewho,whatand when of the problem, while the focusgroup aimed to identify the why and howof the problem.

“The surveys really help you get a senseof trends of issues, whether (or notthey’re) trends in behavioral health and

substance misuse,” said Maj. Donell Bar-nett, BSHOP chief of Field Investigationsand Program Evaluation. Barnett alsoexplained the importance of focus groups,saying they can help provide the story toexplain the numbers, allowing the team tobe better informed and able to intervene ifthere is a problem.

The survey covered topics such asdemographics, social support and person-al experiences. The focus group discussedgroupdynamics, living and social environ-ments, and the Soldier’s basic week.

“Behavioral health allows Soldiers towork on issues and get the assistance theydeserve,” Barnett said. “I think it’s a goodthing for Soldiers and readiness, and itallows them to focus better on themission.”

The BSHOP team is part of the APHC’sClinical Public Health and EpidemiologyDirectorate and is made up of publichealth and behavioral health profession-als. After identifying the problems,BSHOP will make suggestions to Armycommanders tohelp themsolve problems.

These recommendations could lead tochanges in policies and procedures.

For more information on the APHC’sBSHOP Program, contact:

Army Public Health Center, http://phc.amedd.army.mil

Military Crisis Hotline, 1-800-273-TALK (8255)

Military One Source , 1-800-342-9647The Defense Center of Excellence,

1-866-966-1020

HEALTHFrom page B1

51. Protect fragile items before storing them or sending them in the mail.

2. Line pet cages or litter boxes to keep them tidy.

3. Save the counter from a gluey, glittery mess during your next craft project.

4. Clean glass or windows for a streak-free shine.

5. Make a weed barrier in a flower bed or garden before laying new topsoil.

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