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Flow of Patients Through the Trial Nissen SE, et al. JAMA 2008;299:1561-73

Flow of Patients Through the Trial Nissen SE, et al. JAMA 2008;299:1561-73

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Baseline and On-Treatment Vital Signs and Laboratory Values in Participants Completing the Trial (n=360) a Nissen SE, et al. JAMA 2008;299:

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Page 1: Flow of Patients Through the Trial Nissen SE, et al. JAMA 2008;299:1561-73

Flow of Patients Through the Trial

Nissen SE, et al. JAMA 2008;299:1561-73

Page 2: Flow of Patients Through the Trial Nissen SE, et al. JAMA 2008;299:1561-73

Baseline Demographic Characteristics and Medications at the Time of Randomization

Nissen SE, et al. JAMA 2008;299:1561-73

Page 3: Flow of Patients Through the Trial Nissen SE, et al. JAMA 2008;299:1561-73

Baseline and On-Treatment Vital Signs and Laboratory Values in Participants Completing the Trial (n=360)a

Nis

sen

SE

, et a

l. JA

MA

200

8;29

9:15

61-7

3

Page 4: Flow of Patients Through the Trial Nissen SE, et al. JAMA 2008;299:1561-73

Changes in Mean Hemoglobin A1c, Fasting Plasma Glucose Levels, High-Density Lipoprotein Cholesterol, and C-Reactive Protein During the Trial (n = 360)

Nis

sen

SE

, et a

l. JA

MA

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Page 5: Flow of Patients Through the Trial Nissen SE, et al. JAMA 2008;299:1561-73

Baseline, Follow-up, and Change From Baseline in Intravascular Ultrasound End Points

Nissen SE, et al. JAMA 2008;299:1561-73

Page 6: Flow of Patients Through the Trial Nissen SE, et al. JAMA 2008;299:1561-73

Primary Efficacy Parameter (Percent Atheroma Volume) in Prespecified Subgroups

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SE

, et a

l. JA

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Page 7: Flow of Patients Through the Trial Nissen SE, et al. JAMA 2008;299:1561-73

Change From Baseline in Intravascular Ultrasound End Points Using Imputed Values for Noncompleters

Nissen SE, et al. JAMA 2008;299:1561-73

Page 8: Flow of Patients Through the Trial Nissen SE, et al. JAMA 2008;299:1561-73

Clinical End Points, Adverse Events, Laboratory Abnormalities, and Reasons for Discontinuing Participation (Safety Population, n = 543)

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SE

, et a

l. JA

MA

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8;29

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61-7

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