Integumentary 2 t

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    The Integumentary System

    Chapter 6

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    • Organs are two or more tissues whichtogether perform a specialized function.

    • Epithelial membranes are thin structures

    that usually contain both epithelial andconnective tissue.

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    Three types of epithelialmembranes

    • Serous Membranes – ine cavities and cover organs – Simple s!uamous epi. over loose connective

    tissue – "arietal and visceral portions – Secrete a serous #watery$ fluid for lubrication

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    • Mucous membranes – ine cavities that open to the e%terior – ayer of epithelium over connective tissue&

    epithelium varies with location – Tight 'unctions and goblet cells

    • Cutaneous membrane is the s(in – the ma'or organ of the integumentary system

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    • Integumentary system is the s(in and theorgans derived from it #hair) glands) nails$

    • *ne of the largest organs – + s!uare meters& ,- ,, lbs. – argest sense organ in the body

    • The study of the s(in is Dermatology

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    /unctions0,. 1egulation of body temperature

    – Cellular metabolism produces heat as a waste product .

    –2igh temperature• 3ilate surface blood vessels

    • Sweating

    – ow temperature• Surface vessels constrict• shivering

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    +. "rotectionphysical abrasiondehydrationultraviolet radiation

    4. Sensationtouchvibration

    paintemperature

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    5. %cretion

    7. Immunity8 1esistance

    6. 9lood 1eservoir : ,- ; in a resting adult

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    =natomy

    • pidermis S(in• 3ermis

    • Subcutaneous layer or hypodermis

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    pidermis

    • Stratum basale #stratum germinativum$ – Single layer of cuboidal to columnar cells – Stem cells that produce (eratinocytes – >elanocytes ? the same for all races

    • >elanin produced in a melanosome

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    • Stratum spinosum #thorn li(e) pric(ly$ – : ,- layers attached by desmosomes – See spines when cell is stained for

    microscopy – @eratinocytes ta(e in melanin by cytocrine

    secretion

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    • Stratum granulosum – 4 7 layers

    – @eratinization begins here – @eratohyalin found in granules – Cells beginning to die

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    • Stratum lucidum #lucid A clear$ – >ore apparent in thic( s(in – 4 7 layers of clear cells – leidin

    • Stratum corneum #corneum means horny$ – 3ead) flat cells full of (eratin – @eratin is waterproof – Cells are shed

    • 9asal cell to surface – about + 5 wee(s

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    3ermis

    • Connective tissue layer • Collagen and elastic fibers) nerves) blood

    vessels) muscle fibers) adipose cells) hair

    follicles and glands.• "apillary layer

    – ,87 of dermis – loose areolar connective

    tissue – 2ighly vascular – 3ermal papillae fingerprints

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    • 1eticular #net$ layer – 3ense irregular connective tissue – Sebaceous #oil$ glands – 2air follicles – 3ucts of sudoriferous #sweat$ glands – Striae or stretch mar(s – >eissnerBs corpuscles and "acinian

    corpuscles

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    2ypodermis

    • =ttaches the reticular layer to theunderlying organs

    • oose connective tissue and adiposetissue

    • >a'or blood vessels – rete cutaneum

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    =ccessory organs or epidermalderivatives

    • 2airs – pidermal growths that function in protection – Shaft) root) and folllicle – Sebaceous glands) arrector pili muscle) and

    hair root ple%us #touch$ – 2air growth and replacement have a cyclical

    pattern – male patternB baldness

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    Dails

    • "lates of highly pac(ed) (eratinized cells• "rotection) scratching) E manipulation

    • /ormed by cells in nail bed called thematri% # in area of lunula$• , mm 8 wee(

    • ponychium cuticle

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    S(in Flands

    • Sebaceous (oil) glands – Gsually connected to hair follicles – 2olocrine glands – /ats) cholesterol) proteins) salts) and cell

    debris – >oistens hair and waterproofs s(in

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    • Sweat (sudoriferous) glands – Eccrine sweat glands

    • Merocrine glands• Water, salt, wastes• unction is to cool the body (also ner!ous)

    – "pocrine sweat glands• #arger, merocrine glands• "ssociated with hair follicles

    • More !iscous $ fatty acids and proteins• Odor occurs when bro%en down by bacteria

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    • Ceruminous glands – >odified sudoriferous glands – Secrete cerumen #ear wa%$

    • Mammary glands – Secrete mil(

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    S(in color

    • Fenetic factors – Same number of melanocytes – =lbinism

    • nvironmental factors – Gv light or % rays

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    • "hysiological factors

    – =mount of blood – =mount of o%ygen

    • Cyanosis• Carotene accumulation• Haundice – liver disorder

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    ound healing

    • Inflammation – 9lood vessels dilate and become permeable

    • 2eat) redness) swelling and pain

    • Shallow cuts – pithelial cells migrate

    – Contact inhibition

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    3eeper wounds

    • Inflammatory phase – /ibrin forms clot

    • >igratory phase – /ibroblasts ma(e granulation tissue

    • "roliferative phase

    • >aturation phase• Scars – hypertrophic scar – (eloid

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    9urns

    • /irst degree or partial thic(ness burn – *nly epidermis is damaged – rythema) mild edema) surface layer shed – 2ealing – a few days to two wee(s – Do scarring

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    • Second degree deep partial layer burn – 3estroys epidermis – 9listers form – 2ealing depends on survival of accessory

    organs

    – Do scars unless infected

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    • Third degree or full thic(ness burn – 3estroys epidermis) dermis and accessory

    organs of the s(in – 2ealing occurs from margins inward – S(in grafting may be needed

    • =utograft• 2omograft

    • 1ule of Dines

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