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LeptospirosisLeptospirosis
An Emerging Infectious DiseaseAn Emerging Infectious Disease
Dr. dr Sahala Panggabean. Sp.PD KGHDr. dr Sahala Panggabean.
Sp.PD KGH
Christian University of Indonesia,
Faculty of Medicine
Jakarta 12 April 2016Jakarta 12 April 2016
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Synonyms
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Over View
Most common, underdiagnosed zoonosis India cases are reported
!rom Kerala, "amil
#adu, $P, Karnata%a, Maharashtra, Gu&arat '$ndamans.
Source $nimals (rodents and domesticanimals)
*pidemiological !actors
+ontaminated enironment, -ain!all
High ris% groups, endemic in all states o! India
irst description b/ 0eil in 1223
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Over View continued
-ural 4 5rban
Male 4 emale (16 7 1)
+linical eatures mild to seere li!e
threatening
Mimics man/ common !ebrile illnesses
Diagnosis di8cult to con9rm
"reatment e:ectie, i! started earl/ (; +on&unctial
su:usion@hemorrhage$nterior ueitis, Iritis,
Iridoc/clitis,chorioretinitis
Bccurs in F =ee%s to 1 /r. (aerage 3 months)
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)iff
erential)ia"nosis
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La+oratory Tests
"+ @ D+ @ *S- @ Hb @ Platelet count
Serum ilirubin @ SGB"@ SGP"
lood 5rea, +reatinine ' *lectrol/tes
+hest -a/> *+G"ests !or diagnosis o! Eeptospirosis
+ulture !or Eeptospira7 Positie
M$"> Sero conersion or L !old rise@ high
titer *EIS$ @ MS$" 7 positie
M$"7 Microscopic agglutination test
(M)S$"7 Microscopic slide agglutination "est
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(ro+lems in )ia"nosis
DipS"ic%s (Panio, Inc> altimore,Mar/land)
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Interretation of Tests
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Interretation of Tests
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Time #elationshi of Tests
ELI%A or %AT
$AT
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'O %uide - Faine.s
Criteria
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*roach to )ia"nosis
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Treatment
Bral "reatment to 16da/
IC "reatment < to da/s
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Secial Measures
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(ro"nosis and Mortality
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(revention
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