Megha Kamath3 Warwick Street, Apt 2, Boston, MA 02120. 617-602-2888. kamath.me@husky.neu.edu

Profile:Highly proficient research engineer with three years’ experience developing cell culture techniques, extensive immunostaining, and imaging expertise. Interested in working in the biomedical and biotechnology industries utilizing experience to design engineering and biological solutions for drug delivery systems.

Technical skills: Chemical vapor deposition, Cortex Motion Analysis, Critical point drying, Electrophoresis, Engauge Digitizer, Experimental design, Flowcytometry, Imaging (SEM, E-SEM, fluorescence, confocal) Immunostaining, Origin software, Particle size analyzer, MATLAB, Microsoft Office, Mimics, Mammalian cell-culture

Education:Northeastern University, Boston, MAPhD: Candidate, Pharmaceutical Sciences, Interdisciplinary Anticipated graduation 2018Northeastern University, Boston, MAMS: Pharmaceutical Sciences, Drug Delivery systems May 2015Drexel University, Philadelphia, PABS: Biomedical Engineering, Tissue Engineering June 2011

Research Experience: Northeastern University January 2014 - present

Research and Teaching Assistant: Development of an in-vitro model of the small intestine as a platform to study Inflammatory Bowel Disease (IBD) Cultured CaCo-2, HT29, primary mouse and human intestinal stem cells, and human derived peripheral blood

mononuclear cells (PBMCs) to mimic epithelial cell growth representative of the small intestine Chemical vapor deposition (CVD) of parylene and PDMS on tissue samples to obtain crypt-villi structures of the

intestine and study the effect of topography on cell growth and proliferation Characterization of hydrogels as a substrate for the model system Growth and expansion of primary intestinal stem cells on ECM-coated transwells to characterize cell phenotype

native to the intestine Isolated peripheral blood mononuclear cells from human blood and differentiated into dendritic cells to

represent the immune system in the model Contributed expertise used in grant writing and industry publications Responsible for preparing learning material, class lectures, and dissection technique demonstrations related to

anatomy, physiology and biochemistry for over 50 students

Northeastern University September-November 2013 Research Assistant: Development of nanosensors for monitoring changes in disease Developed and quantified sodium nanosensors for working within the intracellular concentration range Used Origin software to quantify research data allowing for a clearer understanding of nanosensor optimization

Drexel University November 2011- August 2012 Researcher: Analysis of physiological functions that are affected in scoliosis Contributed to quantification of spine and thoracic cage structure and its correlation to pulmonary function in

scoliosis patients using Engauge Digitizer software Quantified vertebral and rib sections using Mimics software for cross comparison of scoliosis between species Analyzed kinematics of dynamic cars to study the seat-belt system during car crashes

Megha Kamath BARD Holding, Inc. March-September 2011 Research and development: Technical Assistant

Analyzed algal cultures using a flowcytometer for lipid and chlorophyll production Engineered process flow of cultures for optimum algal growth and high lipid content Constructed quality protocols and standard operating procedures for proper application of reagents, media, and

instrumentation for a start-up laboratory

National Center for Biological Sciences, TIFR Bangalore, India December 2009-March 2010Research trainee: Behavioral and Neurobiology Laboratory Studied native navigation patterns of Drosophila melanogaster larvae for comparison across varied stimuli Used MATLAB to develop tracking data and quantified movement parameters between larvae Modeled a real time system for the behavior of larvae in their natural environment

Publications:Complex, multi-scale small intestinal topography replicated in cellular growth substrates fabricated via chemical vapor deposition of Parylene C . Abigail N. Koppes, Megha Kamath, Courtney A. Pfluger, Daniel D.

Burkey, Mehmet Dokmeci, Lin Wang, Rebecca L. Carrier. Biofabrication, 2016 (in print).

Abstracts for conferences

Hydrogels Containing Biomimetic Topographical Features for Small Intestinal Model Systems. Megha Kamath1,2, Abigail. N. Koppes1, Rebecca Carrier1. Materials Research Society, 2014

Biomimetic Topographical Replicas of Small Intestine For Regenerative Medicine and Drug Delivery Platforms. Abigail Koppes, Robert Montgomery, Megha Kamath, David Breault, Rebecca Carrier. American Institute of Chemical Engineers 2014

Reviewed articles

Biomimetic Intracellular Matrix Materials and Functions from Gel Membrane Electrodes. Toribio F. Otero and Jose G. Martinez.1 Center for Electrochemistry and Intelligent Materials (CEMI), Universidad Politécnica deCartagena, Cartagena, 30203, Spain. MRS 2014 Fall Proceedings.

Leadership/ Mentorship:

Trained fellow graduate and undergraduate students in cell culture techniques and microscopy Mentored high school students on the use of a motion analysis hardware to track changes in heart rate, muscle

involvement and muscle tension while performing an activity Judged the Northeastern University wide RISE competition 2 consecutive years as a peer-judge and gave critical

input towards award-winning graduate students