MUCLUC. .

ChU'O'ng1. SI)' TU'O'NG TAc COA SONG f>leN Tlr vA V~T CHAT1.1. Buc x~ di~n tu 51.2. Cac d~c trung cua buc x~ di~n ill 51.3. MQt s6 vi d\l 61.4. Vung ph6 di~n ill 71.4. Tuang tac cua buc x~ di~n tu va v~t chfrt 81.5. S\1hfrp th\l va S\1buc x~ 91.6. D~c trung cua cac bang hfrp th\l trong ph6 d6 91.7. Chi s6 thi~u h\lt hydro hay qui t~c Yang. Qui t~c 13 11

ChU'O'ng2. PHO Tlr NGO~I vA KHA KIEN2.1. Ma dAu 142.2. Djnh lu~t hfrp th\l 142.3.Ph6k€UV-VIS 152.4. Ban chfrt cua cac kich thich electron 152.5. S\1t~o thanh cac bang song hfrp th\l 182.6. Ki hi~u cac bang song hfrp th\l 192.7. Qui t~c chQn l\1ava cucyogdQ 192.8. Chromophor va auxochrom 202.9. Ph6 d6 222.10. Dung moi 232.11. Hi~u ung dung moi d€n vi trf va wOng dQC\1Cd~i hfrp th\l 252.12. Nguyen If Frank-Condon va hinh d~ng ducyoghfrp th\l 262.13. Ph6 ill ngo~i va kha ki€n cua hQ'Pchfrt huu cO' 282.14. Ph6 kha ki€n: mau s~c cua hQ'pchfrt 572.15. Ung d\lng cua phuang phap ph6 UV-VIS 582.16. PhuO'ng phap giai thich ph6 UV-VIS 62Bai t~p

ChU'O'ng3. PHO HONG NGO~I vA PHO RAMANPhan 1. Ph6 hOng ngo~i

3.1. CO'So' If thuy€t cua ph6 IR 72

3.2. Phuo'ng phap ghi ph6 IR3.3. Ph6 k~ h6ng ngo?i3.4. SI,fh&p thl,l IR3.5. SU dl,lng ph6 IR3.6. Tinh ch&t lien k~t va khuynh huang h&p thl,l buc X? IR3.7. Bi~u d6 tuong quan va bang tAn s6 d~c trung3.8. Cac y~u t6 anh huong d~n tAn s6 nh6m3.9. Ph6 IR cua hQ'p ch&t huu co3.10. Phuong phap giai thich ph6 IR

PhAn 2. Ph6 Raman3 .11. Hi~u ung Raman va ngu6n g6c cua phuong phap ph6 Raman3.12. Li thuy~t cua hi~u ung Raman va ph6 Raman3.13. Ph6 quay Raman thuAn tuy3.14. D?ng phan tu va ph6 quay Raman3.15. Ph6 dao dQng-quay Raman3.16. SI,fphan CI,fCcua cac v?ch Raman3.17. Qui t~c lo?i tric qua I?i3.18. May ph6 Raman3.19. Ch~ t?O mfiu do3.20. (fng dl,lng cua ph6 Raman3.21. SI,f khac nhau giii'a ph6 Raman va ph6 huynh quang3.22. SI,f khac nhau gifra ph6 Raman va ph6 IRBai t~p

7576808182878896

141

143145149151152152153153155155158159163

ChU'O'ng4. PHO CQNG HU'ONG Tll H~ T NHANPhAn 1. Khili ni~m cO' 560

4.1. MadAu4.2. Celu truc cua nguyen tu4.3. H?t nhan trong tu truemg4.4. SI,fkich thich va Sl,fh6i phl,lC4.5. Phep thl,fc nghi~m xung hoa4.6. SI,fche ch~n va dQ chuy~n dich hoa hQc4.7. SI,ftuong duang hoa hQc4.8. Ph6 k~ cQng hucrng tic h?t nhan4.9. Cuemg dQ pic help thl,l va duang cong tich phan4.10. M6i truang hoa hQCva dQ chuy~n dich hoa hQC4.11. Cac y~u t6 anh huang d~n dQ chuy~n dich hoa hQc4.12. SI,f phan tach spin-spin. Qui t~c (n+ 1)4.13. So sanh ph6 NMR o· wang dQ tic truemg th&p va cao4.14. Ph6 IH NMR cua cac hQ'p chelt huu co

185185188194197199200201209210213217228229

Phin 2: Ph6 Carbon-13, s" ghep c,p vai cae h,t nhin khac4.15. H~t nhan carbon-I 3 2454.16. D¢ chuy~n dich hoa hQCcarbon-I 3 2464.17. Ph6 13C ghep c~p proton: S\l phan tach spin-spin cua cac tin hi~u carbon-13 2484.18. Ph6 13C NMR xoa ghep c~p proton 2504.19. Hi~u (mg Overhauser h~t nhan (NOE) 2514.20. S\l phan C\lCcheo: Ngu6n g6c cua hi~u (mg NOE 2534.21. Cac qua trinh h6i ph\lC phan tir 2564.22. S\l xoa ghep off-resonance 2584.23. Khai luQ'cv~ ph6 DEPT 2594.24. Ph6 13C NMR cua hQ'PchAt v6'i m~ch hydrocarbon no - Cac carbon tuong 261duong4.25. Cac hQ'PchAt chua vong tham 2634.26. Dung moi cho ph6 carbon-I 3 NMR - S\l ghep c~p cua carbon v6'i deuteri 2654.27. S\l ghep dj h~t nhan cua carbon-13 v6'i fluor-19 2684.28. S\l ghep dj h~t nhan cua carbon-I 3 v6'i phosphor-31 2704.29. Phuong phap gilii ph6 carbon-13 va proton NMR d~ xac djnh cAu truc 271

Phin 3. S" ghep c,p spin-spin4.30. H~ng s6 ghep c~p: Ki hi~u va ccrch~ 2734.31. S\l tuong duong v~ m~t tir 2854.32. Ph6 cua cac M diastereotopic 2904.33. S\l khong tuong ducrng trong m¢t nh6m 2954.34. Xac dinh cac h~ng s6 ghep c~p tir ph6 b~c m¢t 2974.35. Ph6 b~c hai. S\l ghep c~p m~nh 3044.36. AIken 3134.37. Phan tich h~ ph6 allylic 3164.38. Cac hQ'PchAt tham 3204.39. S\l ghep c~p trong cac h~ dj vong 327

Phin 4. MQt s6 hi~u(Png d,c bi~ttrong ph6 1-0 NMR4.40. Proton tren oxy: Alcohol 3304.41. S\l trao d6i trong H20 nu6'c va trong 020 3334.42. Cac d~ng trao d6i khac: Hi~n luqng tautomer 3364.43. Proton tren nitrogen 3384.44. Cac amid 3424.45. Hi~u (mg clia dung moi d8n d¢ chuy~n dich hoa hQc 3454.46. Cae tac nhan chuy~n djch hoa hQC 348

Phin 5. Ph6 NMR tU'O'ngquan va ph6 2-0 NMR4.47.DEPT 3514.48. Ccr So' Ii thuy~t 3554.49. Ph6 tuong quan 358Bili t~p 396

ChU'O'ng5. PHO KHOI LU'Q'NG5.1. M6' dAu 4265.2. Qua trinh phan manh 4265.3. Cac phuong phap ion hoa 4285.4. Phan tich ph6 4395.5. Phat hi~n va dinh lUQ11g 4495.6. Xac dinh trQng lUQ'ngphan tfr 4535.7. Xac dinh cong thuc pMn tfr 4555.8. Phan tich cAu truc va cac ki~u phan manh 4605.9. Ph6 kh6i lUQ11gclia cac hQ'PchAt 4655.10. Phuong phap pMn tich ph6 MS . 5355.11. S\f phil hQ'Pclia ph6 v6'i cac thu vi~n ph6 536BAi~p 537

ChU'O'ng6. PHO NMR CUA MQT sO H~ T NHAN QUAN TRQNGKHAc c6 SPIN Yz

6.1. Ph6 1~ NMR 5556.2. Ph6 19F NMR 5586.3. Ph6 29Si NMR 5616.4. Ph6 31p NMR 563

ChU'O'ng,7. K~T HQ'P cAc PHU'O'NG PHAp PHO TRONG xAc elNHcAu TRUe

7.1. Vi d\l 1 5677.2. Vi dv2 5687.3. Vi dv3 570BAi~p 572

flap an va lai giai 616

Phin Ph••.•I••.•c 621

Tai Ii,u tham khao 667